WCHR 2014 Presentations (Community-funded)

[Thinning87]

it says channel does not exist

[David7]

New videos https://www.youtube.com/channel/UCJn...bGaoOWFS6kRxDQ

[nameless]

Histogen and CB have a good chance of coming out in a few years. I think Histogen will give really good results. Just check out the results from the adipose derived stem cell paper, which is a very similar therapy.

Replicel I'm 50/50 about. But their results must have been pretty good for Shisheido to fund them.

I don't know what to make of Follica since what Cots said just now is at odds with what the company said last year (that they were making substantial new hairs in humans). The optimist in me says that Cots was just playing coy.

*Creating hair follicles in vitro and then implanting them onto the scalp seems like a really backasswards way of doing things, but unfortunately that seems to be the aim of most research right now. I'm not sure why you'd want that. It's not even hair restoration, but another kind of hair transplant. The results will never look natural and will depend on surgeon skill, etc.

* I also think that Histogen might turn out to be a great treatment if you do follow up treatments every few weeks until you get your hair back and then maybe once every 3 months or so to preserve it.

* I also don't know what to make of Replicel and I wonder why Shisheido funded them if they haven't made progress over their first trial. I think they must have made some progress or else they would have withered away like Aderans.

* I also don't know what to make of Follica. They've got a treatment that would only take a few years to get to market but it won't cure everyone. But it's significantly better than the minox + propecia regimen that's available now. I think that if they want to make money in hair growth they should bring this treatment to market asap because other scientific groups will be bringing total cures to market in about 7 years or so, and then Follica's plans to make money by curing hair loss will be lost. If they bring their treatment to market asap then they could retire minox and propecia, and take over the hair growth market for themselves for the next 7 years or so. And that market would be a lot bigger than it is now since everyone knows that minox + propecia profits are hindered by poor efficacy efficacy and disconcerting side effects. If Follica really has a better treatment that they could get to market in a year or two then they could make greater profits because Follica would get more customers since their treatment works better.

[hiko]

sigh, these presentations are depressing. There is still so much they have no idea about, and it doesn't seem like anyone is even close to making a new therapy. I really hope the stem cell guys crack the inductivity issues soon, because short of making brand new follicles, I don't think anyone is going to figure out or start treating the pathways that cause baldness. It's crazy that blocking androgen production is so effective for baldness prevention, but none of these downstream pathways are yielding any good results. I don't think anyone is ever going to reverse complete baldness without actually implanting new follicles. the whole wounding thing is a joke, it's so far behind what people what lauster and gardner are doing, who the hell would want to figure out how to initiate a new follicle from wounding when you can just make a new one in vitro? I'm guessing this is why follica is having funding issues.

Let's keep our fingers crossed that these regeneration teams pull something amazing in the next two years, i think if they can make new follicles then things like histogen and replicel will be very effective as a supplemental treatment. It would be really nice if we had something other than ****ing propecia right now, it really sucks that no one has pushed a safe anti androgen through, because I think once the scalp gets too bald, i think it's going to be very difficult to make good hair. I think hair doctors are assholes for promoting propecia as a safe drug, it's so obviously far from that.

Histogen and CB have a good chance of coming out in a few years. I think Histogen will give really good results. Just check out the results from the adipose derived stem cell paper, which is a very similar therapy.

Replicel I'm 50/50 about. But their results must have been pretty good for Shisheido to fund them.

I don't know what to make of Follica since what Cots said just now is at odds with what the company said last year (that they were making substantial new hairs in humans). The optimist in me says that Cots was just playing coy.

Creating hair follicles in vitro and then implanting them onto the scalp seems like a really backasswards way of doing things, but unfortunately that seems to be the aim of most research right now. I'm not sure why you'd want that. It's not even hair restoration, but another kind of hair transplant. The results will never look natural and will depend on surgeon skill, etc.

TL;DR: the point is, if you value your hair, jump on treatments now, because new therapies are years away at best. It's why I jumped on Dut 7 months ago after noticing hairline thinning and some recession. You can't wait until you lose a lot of hair and then go on treatments. Starting Fin or Dut early gives the best chance at regrowth and thickening.

[artika]

Hey Desmond,

First of all, thanks for the amazing work you have done!

Secondly, what's the situation with the Dr Lindner/ Beren Atac interview?
You maybe said that's the most promising, so when do you think you will be able to post that?

Thanks for everything!

[hellouser]

Desmond... you'll need to look at the youtube video's ID number;

https://www.youtube.com/watch?v=TN5H01HGaVI

Then wrap it around like so:

[youtube2]TN5H01HGaVI[/youtube2] 

And you'll get this:

[Desmond84]

Hey guys can someone help me lol..

How do you embed a YouTube video in your post?

[Thinning87]

sigh, these presentations are depressing. There is still so much they have no idea about, and it doesn't seem like anyone is even close to making a new therapy. I really hope the stem cell guys crack the inductivity issues soon, because short of making brand new follicles, I don't think anyone is going to figure out or start treating the pathways that cause baldness. It's crazy that blocking androgen production is so effective for baldness prevention, but none of these downstream pathways are yielding any good results. I don't think anyone is ever going to reverse complete baldness without actually implanting new follicles. the whole wounding thing is a joke, it's so far behind what people what lauster and gardner are doing, who the hell would want to figure out how to initiate a new follicle from wounding when you can just make a new one in vitro? I'm guessing this is why follica is having funding issues.

Let's keep our fingers crossed that these regeneration teams pull something amazing in the next two years, i think if they can make new follicles then things like histogen and replicel will be very effective as a supplemental treatment. It would be really nice if we had something other than ****ing propecia right now, it really sucks that no one has pushed a safe anti androgen through, because I think once the scalp gets too bald, i think it's going to be very difficult to make good hair. I think hair doctors are assholes for promoting propecia as a safe drug, it's so obviously far from that.

Well, don't you think the researchers developing these methods would take these factors in consideration? They must know it's hard to work with all these pathways.

[sdsurfin]

also desmond, where's the team germany presentation? that's really the only one I'm interested in, except for maybe garza's. Curing baldness chemically looks like a pretty insurmountable task if we don't just use something lke propecia which basically takes an axe to your vital pathways. let's get someone 3D printing new follicles asap, i think once they make new inductive hair germs or new whole follicles, then adapting their environment will be a much easier way to go.

[sdsurfin]

sigh, these presentations are depressing. There is still so much they have no idea about, and it doesn't seem like anyone is even close to making a new therapy. I really hope the stem cell guys crack the inductivity issues soon, because short of making brand new follicles, I don't think anyone is going to figure out or start treating the pathways that cause baldness. It's crazy that blocking androgen production is so effective for baldness prevention, but none of these downstream pathways are yielding any good results. I don't think anyone is ever going to reverse complete baldness without actually implanting new follicles. the whole wounding thing is a joke, it's so far behind what people what lauster and gardner are doing, who the hell would want to figure out how to initiate a new follicle from wounding when you can just make a new one in vitro? I'm guessing this is why follica is having funding issues.

Let's keep our fingers crossed that these regeneration teams pull something amazing in the next two years, i think if they can make new follicles then things like histogen and replicel will be very effective as a supplemental treatment. It would be really nice if we had something other than ****ing propecia right now, it really sucks that no one has pushed a safe anti androgen through, because I think once the scalp gets too bald, i think it's going to be very difficult to make good hair. I think hair doctors are assholes for promoting propecia as a safe drug, it's so obviously far from that.

[David7]

2 new video's , check Desmond's channel .

https://www.youtube.com/channel/UCJn96v_HIbGaoOWFS6kRxDQ

[Thinning87]

sounds like a pretty good presentation but can someone explain what the heck he's saying

[David7]

New video.

[Swooping]

Looks like Desmond posted a new video!

Elaine Chew: Transcriptosome differences between Balding and Non-Balding DP Cells

Link:
https://www.youtube.com/watch?v=IEbLm_cgJKI

Man I do feel like that was a pretty straightforward and not interesting presentation at all? Especially the link with minoxidil (vascularization > vegf) come on, could have been more in depth! Keep posting them desmond, gj!

[Thinning87]

Every little bit helps:

"Mechanical stimulation:
Mechanical stimulation of angiogenesis is not well characterized. There is a significant amount of controversy with regard to shear stress acting on capillaries to cause angiogenesis, although current knowledge suggests that increased muscle contractions may increase angiogenesis. This may be due to an increase in the production of nitric oxide during exercise. Nitric oxide results in vasodilation of blood vessels."

Resistance scalp exercises can't hurt.

35YrsAfter also posts as CITNews and works at Dr. Cole's office
forhair.com
Cole Hair Transplant
1070 Powers Place
Alpharetta, Georgia 30009
Phone 678-566-1011
email 35YrsAfter at chuck@forhair.com
The contents of my posts are my opinions and not medical advice
Please feel free to call or email me with any questions. Ask for Chuck

What does that imply