Sm04554

[machi]

after the disappointment of yesterday the results of CB- 03-01 , is it possible to get samumed in the same way that we can use CB- 03-01 ? I mean if we can get samumed in Kane or another laboratory.
I can not wait any longer , I 'm going bald and I can not go outside without toppik .

[Hemo]

How often does this chemical get applied? Once a day?

I believe the trials have been once per day but who knows until it's potential release.

[allTheGoodNamesAreTaken]

How often does this chemical get applied? Once a day?

[rdawg]

Does anyone think that SM could potentially have worse side effects than finasteride? What kind of side effects could we expect from this type of drug?

Nothing has been found to be dangerous with this drug yet from the 1.5 years it's been in trial.

Cancer is a major related possibility, but there is no evidence of this drug causing that yet at all, they believe the molecule does not stay in the system long enough to cause something like that.

Believe me they would discover something like that before it's release, you would notice that after 3 years or so of trials.

[IvanXproject]

Cancer

That is way worse than the finasteride side effects..

[s991]

Does anyone think that SM could potentially have worse side effects than finasteride? What kind of side effects could we expect from this type of drug?

Cancer

[IvanXproject]

Does anyone think that SM could potentially have worse side effects than finasteride? What kind of side effects could we expect from this type of drug?

[Trouse5858]

Is one year the average length trial for a phase III? I feel like I've read about some that were upwards of 2 years. And what's the latency period in terms of getting it to market, like what's the final step after this trial?

[rdawg]

I think results equal to minox if just by a different method would still be worth pursuing. Regrowing hair is so hard to do I think anything remotely significant is worth going after. You could always stack this and minox and get double the results. Just have your wallet ready the stuff wont be cheap

Minoxidil is borderline garbage, it was worth selling back in the 80's-90's as there were literally zero alternatives and it maybe gave you a 10% improvement(more on very few patients).

it did nothing for me and numerous others, gives a slight thickening affect if anything.

there is no way to sell a product like minoxidil, at the very least this is 10-20% better going by that article from december, but we dont know how much better.

and yes as above said, Everything revolving around this drug has been good so far, and we know it's better than minox(they said they achieved results on late stage hairloss guys, not early stage like minox) but safety is a massive concern which will take at least a year long trial to figure out with a product like this which affects the WNT pathway.

hopefully they pursue a phase III right away though, meaning this product would be 2 years away max.

[burtandernie]

I think results equal to minox if just by a different method would still be worth pursuing. Regrowing hair is so hard to do I think anything remotely significant is worth going after. You could always stack this and minox and get double the results. Just have your wallet ready the stuff wont be cheap

[Tomtom21]

I think we all need to just take a minute and take a deep breathe bc we are all getting ahead of ourselves. We are going to find out in 11 days so patience people. It is hard to believe that the trial did not produce at the very least superior results to minoxidil, but all at this time is pure speculation. We are all hoping for the crap your pants, mind blowing results, but time will tell. If it is one thing we have learned from AGA, with all these treatments and hopes, is hope for the best, but expect the worst.
Lastly, I really think that they have something (I wont speculate as to what I think that is), but we also need to be circumspect bc wnt pathway is a/w cancer risks. This supplemental trial will further support a safety profile or **** the product all together (similar occurrence with the product from curis years ago - it was effective but carcinogenic and therefore trashed). So everybody keep their heads on their shoulders and lets just wait and see.

[Hemo]

I'm slightly confused.. I read that study that was published In December just now, and it says , to sum it up, positive results on Norwood 4 and greater. So why is there hype now, and not directly after the hairless conference? I've read somewhere they are posting something in early March, is this the actual hair % increase and density growth, pictures, or what ?

That was a preliminary release within 2 weeks of the conclusion of their trial. They since did more thorough analyses, which are being presented on 3/5.

[Hubris]

The exact results will be heard in less than two weeks, we know it's good, but how good is the question!

I think we have to assume that the results are at least better than minoxidil. If the results were less than or equal to minoxidil, it would be unlikely that they would wish to pursue further clinical trials. Thus, there is definitely room here for cautious optimism.

[rdawg]

I'm slightly confused.. I read that study that was published In December just now, and it says , to sum it up, positive results on Norwood 4 and greater. So why is there hype now, and not directly after the hairless conference? I've read somewhere they are posting something in early March, is this the actual hair % increase and density growth, pictures, or what ?

No it was just a preview back in december, there was hype back then as well(cautious optimism for the most part)

The fact that they were near the end of the trial and seeing positive results, then stating they were going to review the results further and right away releasing those results is an incredibly good sign.

usually when it's been bad news, there has always been a delay, but with this product they have been vocal for a few months about it, and that article just mentions that they are seeing very positive results.

The exact results will be heard in less than two weeks, we know it's good, but how good is the question!

[BrianH123]

I'm slightly confused.. I read that study that was published In December just now, and it says , to sum it up, positive results on Norwood 4 and greater. So why is there hype now, and not directly after the hairless conference? I've read somewhere they are posting something in early March, is this the actual hair % increase and density growth, pictures, or what ?