George Cotsarelis and upenn new article today

[moore]

http://www.utrend.tv/v/one-second/

Have you ever imagined the face you would do when you get such ridiculous volume on your head!?
Come on researchers!

[hellouser]

http://www.utrend.tv/v/one-second/

Have you ever imagined the face you would do when you get such ridiculous volume on your head!?
Come on researchers!

Now how about some REAL hair for bald/balding men and women?

Forget these ultimately useless youtube campaigns trying to make everyone feel warm and fuzzy, JUST RELEASE A GOD DAMN PRODUCT!!!

[CAlex]

Hellouser I actually like most of your posts and thoughts but recently your just ranting mate. I dont mean to offend you with this comment but just relax.

Your acting as if there is a treatment that could be released already. I realize we all have our good and bad days on here and sometimes its hard keep from going off. I also know everyone's sick of hearing this but we are getting closer to real treatments, whether thats 5-10 or more years away no one knows.

At least we are living in a time where the researchers have the tools to better understand and create better treatments. If you look back just 20 years ago I dont think it would have even been possible to come up with a treatment.

we dont need any one or company to want to cure us or make our lives better to get a cure. thats not how the world works. All we need is for there to be continued breakthroughs so eventually a whatever is needed for a cure is just known and then investors will flock to invest in companies like histogen. In a few years we might know exactly what has to be done to cure/reverse hair loss and that makes coming up with a treatment much easier. Right now were still guessing a bit.

throwing temper tantrums saying someone needs to cure us or care about us is just sad. How many people care about curing cancer? How many Billions have gone into cancer research? they are no further along then we are.

[hellouser]

Hellouser I actually like most of your posts and thoughts but recently your just ranting mate. I dont mean to offend you with this comment but just relax.

Your acting as if there is a treatment that could be released already. I realize we all have our good and bad days on here and sometimes its hard keep from going off. I also know everyone's sick of hearing this but we are getting closer to real treatments, whether thats 5-10 or more years away no one knows.

At least we are living in a time where the researchers have the tools to better understand and create better treatments. If you look back just 20 years ago I dont think it would have even been possible to come up with a treatment.

we dont need any one or company to want to cure us or make our lives better to get a cure. thats not how the world works. All we need is for there to be continued breakthroughs so eventually a whatever is needed for a cure is just known and then investors will flock to invest in companies like histogen. In a few years we might know exactly what has to be done to cure/reverse hair loss and that makes coming up with a treatment much easier. Right now were still guessing a bit.

throwing temper tantrums saying someone needs to cure us or care about us is just sad. How many people care about curing cancer? How many Billions have gone into cancer research? they are no further along then we are.

And isn't that just one sad pathetic FAILURE? Forget all the money thats been dumped into a cancer cure... look at all the man hours that have been put in. THATS where the biggest problem is. The same goes for the hair loss solution. At this point... or even years ago, all the results have been and still are unacceptable. If I hear '5-10 years isnt far away' one more time I'm going to vomit. How is that supposed to be positive, for myself and many others to get the false hope that ANOTHER 5-10 years may give us a cure. It was 'in 5-10 years' 5-10 years ago too! Someone at the top needs a kick in the teeth. If youre not angry, you SHOULD be angry. The whole damn hair loss industry has taken us for a ride and the rest of society has turned balding individuals into a JOKE. I'm effing tired of it.

[Scientalk56]

And isn't that just one sad pathetic FAILURE? Forget all the money thats been dumped into a cancer cure... look at all the man hours that have been put in. THATS where the biggest problem is. The same goes for the hair loss solution. At this point... or even years ago, all the results have been and still are unacceptable. If I hear '5-10 years isnt far away' one more time I'm going to vomit. How is that supposed to be positive, for myself and many others to get the false hope that ANOTHER 5-10 years may give us a cure. It was 'in 5-10 years' 5-10 years ago too! Someone at the top needs a kick in the teeth. If youre not angry, you SHOULD be angry. The whole damn hair loss industry has taken us for a ride and the rest of society has turned balding individuals into a JOKE. I'm effing tired of it.

Personally the only thing i had faith in is Histogen. Sadly, things are just getting worse..

The only thing we can do is interviewing Gail Naughton, and get some answers. I have no idea how to get to Spencer. BUT WE HAVE TO.

[Arashi]

And isn't that just one sad pathetic FAILURE? Forget all the money thats been dumped into a cancer cure... look at all the man hours that have been put in. THATS where the biggest problem is. The same goes for the hair loss solution. At this point... or even years ago, all the results have been and still are unacceptable. If I hear '5-10 years isnt far away' one more time I'm going to vomit. How is that supposed to be positive, for myself and many others to get the false hope that ANOTHER 5-10 years may give us a cure. It was 'in 5-10 years' 5-10 years ago too! Someone at the top needs a kick in the teeth. If youre not angry, you SHOULD be angry. The whole damn hair loss industry has taken us for a ride and the rest of society has turned balding individuals into a JOKE. I'm effing tired of it.

It makes me sad to see how all this is getting to you man. It seems you're getting more and more depressed. We all hate baldness and we're all frustrated with the slow progress to some extend but it shouldn't effect your daily wellbeing that much. I'm no psychiatrist but I think you should ask yourself: what difference will a full head of hair make and are there other ways to attain those goals ? Cause honestly, we're years from a cure man. I really think you should go talk to someone, your doctor for example. Nobody needs to suffer like you seem to do from getting bald. There's so much more in life. Good luck man, I really wish you all the best

[hellouser]

It makes me sad to see how all this is getting to you man. It seems you're getting more and more depressed. We all hate baldness and we're all frustrated with the slow progress to some extend but it shouldn't effect your daily wellbeing that much. I'm no psychiatrist but I think you should ask yourself: what difference will a full head of hair make and are there other ways to attain those goals ? Cause honestly, we're years from a cure man. I really think you should go talk to someone, your doctor for example. Nobody needs to suffer like you seem to do from getting bald. There's so much more in life. Good luck man, I really wish you all the best

I have my good weeks and then I have my bad weeks. Sometimes I feel like my hair is doing better and this feeling lasts for a while and then other times when I see myself in the mirror I feel its doing terrible. Those emotions can change rapidly; today I'll feel like my hair has improved with my regimen, the next I'll feel like shit thinking its going down the crapper.

I'm not talking to anyone except for people on the hair loss forums. Why? Because doctor's couldn't give a single shit about you. My mom nearly destroyed her knee last year, her doc kept her waiting with MRI's and advice for months and DISREGARGED physiotheraphy. She's got TWO torn ACL's, torn meniscus, one torn MCL and damaged cartilage. It took her THREE visits over three months and begging to get sent to a specialist. Previously it took 4 months to get an MRI. The system in Canada is bullshit. And given that everyone sees hair loss as a chance for mockery and self superiority, talking to someone WILL make matters worse. You think you or I will get any sympathy out of this? You think any of their meaningless crap they spew out at me will give me hair or anything? They're paid to do that. If my money is going ANYWHERE it will be for hair.... ONLY.

Anyway, I'm *somewhat* lucky. Here's why: Apart from my hairline, you can't tell I have hair loss. I specifically asked my hair stylist to try and differentiate my hair at the top from the back and sides, she said she couldn't really tell much of a difference in terms of density. Where I am now, its basically taken me about 7-10 years to reach and visually hasn't got much worse in the last 4-6 years. I could easily go in for a simple 1,400-1,800 graft hair transplant and get back down to a SOCIALLY TOLERABLE NW2 level. I say socially tolerable, because most, if not damn near all people privileged to HAVE hair, subconsciously have GIMPED those without. THATS why I'm so pissed off. I'm TIRED of feeling as if I'm always on the shit end of the stick. I've got other issues too but I'm not going to get into them. Essentially my life's been one struggle after another. Nothing seems to work out for me.

I have the money to drop on an HT, but given FUT's long stupid scar at the back, FUE's moth eaten scars and Dr Gho's dubious claims of 85% regeneration (yet still limiting his patients to three maximum procedures?! DAFUQ?!)... I'm hesitant to do it. If any HT is going to be a necessity for me, I'm more likely to go with Dr. Wesley and see how HIS claims of regeneration pan out.

This disease is long overdue for a cure. PERIOD. There's no excuse for the stage we're at one month away from 2014.

[hiilikeyourbeard]

I have my good weeks and then I have my bad weeks. Sometimes I feel like my hair is doing better and this feeling lasts for a while and then other times when I see myself in the mirror I feel its doing terrible. Those emotions can change rapidly; today I'll feel like my hair has improved with my regimen, the next I'll feel like shit thinking its going down the crapper.

I'm not talking to anyone except for people on the hair loss forums. Why? Because doctor's couldn't give a single shit about you. My mom nearly destroyed her knee last year, her doc kept her waiting with MRI's and advice for months and DISREGARGED physiotheraphy. She's got TWO torn ACL's, torn meniscus, one torn MCL and damaged cartilage. It took her THREE visits over three months and begging to get sent to a specialist. Previously it took 4 months to get an MRI. The system in Canada is bullshit. And given that everyone sees hair loss as a chance for mockery and self superiority, talking to someone WILL make matters worse. You think you or I will get any sympathy out of this? You think any of their meaningless crap they spew out at me will give me hair or anything? They're paid to do that. If my money is going ANYWHERE it will be for hair.... ONLY.

Anyway, I'm *somewhat* lucky. Here's why: Apart from my hairline, you can't tell I have hair loss. I specifically asked my hair stylist to try and differentiate my hair at the top from the back and sides, she said she couldn't really tell much of a difference in terms of density. Where I am now, its basically taken me about 7-10 years to reach and visually hasn't got much worse in the last 4-6 years. I could easily go in for a simple 1,400-1,800 graft hair transplant and get back down to a SOCIALLY TOLERABLE NW2 level. I say socially tolerable, because most, if not damn near all people privileged to HAVE hair, subconsciously have GIMPED those without. THATS why I'm so pissed off. I'm TIRED of feeling as if I'm always on the shit end of the stick. I've got other issues too but I'm not going to get into them. Essentially my life's been one struggle after another. Nothing seems to work out for me.

I have the money to drop on an HT, but given FUT's long stupid scar at the back, FUE's moth eaten scars and Dr Gho's dubious claims of 85% regeneration (yet still limiting his patients to three maximum procedures?! DAFUQ?!)... I'm hesitant to do it. If any HT is going to be a necessity for me, I'm more likely to go with Dr. Wesley and see how HIS claims of regeneration pan out.

This disease is long overdue for a cure. PERIOD. There's no excuse for the stage we're at one month away from 2014.

god this hits home for me

i'm so sorry we all have to go through this.

[greatjob!]

I have my good weeks and then I have my bad weeks. Sometimes I feel like my hair is doing better and this feeling lasts for a while and then other times when I see myself in the mirror I feel its doing terrible. Those emotions can change rapidly; today I'll feel like my hair has improved with my regimen, the next I'll feel like shit thinking its going down the crapper.

I'm not talking to anyone except for people on the hair loss forums. Why? Because doctor's couldn't give a single shit about you. My mom nearly destroyed her knee last year, her doc kept her waiting with MRI's and advice for months and DISREGARGED physiotheraphy. She's got TWO torn ACL's, torn meniscus, one torn MCL and damaged cartilage. It took her THREE visits over three months and begging to get sent to a specialist. Previously it took 4 months to get an MRI. The system in Canada is bullshit. And given that everyone sees hair loss as a chance for mockery and self superiority, talking to someone WILL make matters worse. You think you or I will get any sympathy out of this? You think any of their meaningless crap they spew out at me will give me hair or anything? They're paid to do that. If my money is going ANYWHERE it will be for hair.... ONLY.

Anyway, I'm *somewhat* lucky. Here's why: Apart from my hairline, you can't tell I have hair loss. I specifically asked my hair stylist to try and differentiate my hair at the top from the back and sides, she said she couldn't really tell much of a difference in terms of density. Where I am now, its basically taken me about 7-10 years to reach and visually hasn't got much worse in the last 4-6 years. I could easily go in for a simple 1,400-1,800 graft hair transplant and get back down to a SOCIALLY TOLERABLE NW2 level. I say socially tolerable, because most, if not damn near all people privileged to HAVE hair, subconsciously have GIMPED those without. THATS why I'm so pissed off. I'm TIRED of feeling as if I'm always on the shit end of the stick. I've got other issues too but I'm not going to get into them. Essentially my life's been one struggle after another. Nothing seems to work out for me.

I have the money to drop on an HT, but given FUT's long stupid scar at the back, FUE's moth eaten scars and Dr Gho's dubious claims of 85% regeneration (yet still limiting his patients to three maximum procedures?! DAFUQ?!)... I'm hesitant to do it. If any HT is going to be a necessity for me, I'm more likely to go with Dr. Wesley and see how HIS claims of regeneration pan out.

This disease is long overdue for a cure. PERIOD. There's no excuse for the stage we're at one month away from 2014.

If you think you're on the "shit end of the stick" try loosing your hair when you're 12 years old. I reached your level of loss when I was in high school.

[strife91]

I feel for u hell, my quality of life has gone to shit from this bs.

[Hicks]

If you need 1500 graphs go get 800-1000 to feed the beast. Yes the medical system is crap but what else is there?

[Thinning87]

As I'm about to go in the shower to get ready for tonight I have a thought about Follica I wanted to share.

I think they might be closer than all us pessimists believe. Reading more into what they are doing, it seems like by now they are testing fgf9 in preclinical and, if successful, they will go to human clinical trials with it. It's been six months since their article actually, so potentially they already have a good idea.

Anyways, it seems like even without fgf9 they had a pretty good idea of how to "consistently" create follicles. It was just a matter of producing a result that was cosmetically significant, and fgf9 seems to be the key to this.

But the fact that they have been able to create new follicles consistently is extremely positive because it shows an understanding of the genesis process. All they need to do now is figure out protocols to efficiently yield significant results that people will pay for, or in other words, a full head of hair.

The investigation has therefore turned to proteins and molecular pathways to up regulate follicular genesis from wounding. As I understand, for how complex it might be, it seems to me like it's only a waiting game until they can find the right combination of proteins to up/down regulate in order to achieve the results we dream of. A waiting game because there is only a finite number of these potential pathways that need to be investigated, for how complex it might be to do so.

This, in perspective, is huge.

[hellouser]

As I'm about to go in the shower to get ready for tonight I have a thought about Follica I wanted to share.

I think they might be closer than all us pessimists believe. Reading more into what they are doing, it seems like by now they are testing fgf9 in preclinical and, if successful, they will go to human clinical trials with it. It's been six months since their article actually, so potentially they already have a good idea.

Anyways, it seems like even without fgf9 they had a pretty good idea of how to "consistently" create follicles. It was just a matter of producing a result that was cosmetically significant, and fgf9 seems to be the key to this.

But the fact that they have been able to create new follicles consistently is extremely positive because it shows an understanding of the genesis process. All they need to do now is figure out protocols to efficiently yield significant results that people will pay for, or in other words, a full head of hair.

The investigation has therefore turned to proteins and molecular pathways to up regulate follicular genesis from wounding. As I understand, for how complex it might be, it seems to me like it's only a waiting game until they can find the right combination of proteins to up/down regulate in order to achieve the results we dream of. A waiting game because there is only a finite number of these potential pathways that need to be investigated, for how complex it might be to do so.

This, in perspective, is huge.

Here's another perspective:

Dr. Cotsarelis has been working on a cure/treatment for hair loss for about a decade. Follica included.

What do they have to show after all this time?

[BDDFreak]

Here's another perspective:

Dr. Cotsarelis has been working on a cure/treatment for hair loss for about a decade. Follica included.

What do they have to show after all this time?

Lol I wish there was a company who had all bald/balding employees working on a cure. The incentive factor alone would get us the cure in no time. I'm with u man. They should have a viable treatment by now, but it's also good to remember they don't owe us anything. We haven't personally invested in their product (unless u have then im extremely sorry). Whatever they're working on still seems to have financial backing as far as investors go so there has to be something there for them to show. It's just a matter of when.

Honestly though putting all frustration aside, I can't say I'm mad even if they are just beating around the bush and trying to keep their research position because everyone just trying to eat. They have families I'm sure they have to provide for. But I'm sure they also understand how much money they'd be rolling in if they did bring a cure to light.

[Kiwi]

Here's another perspective:

Dr. Cotsarelis has been working on a cure/treatment for hair loss for about a decade. Follica included.

What do they have to show after all this time?

Boom! Nadda!

I think the Israeli stuff seems the most promising for 2014 :-/