(CB-03-01 Vehicle Research) PhD Student in Chemistry

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  • adam k
    Member
    • Aug 2013
    • 78

    Originally posted by yan
    "Rapidly converted to its inactive metabolite, Cortexolone, after passing through the skin"
    I know lol that is also confusing the f out of me. How the hell did Ionto manage such few applications.

    Maybe they used the word 'rapid' loosely when they were trying to propose this drug.

    Comment

    • adam k
      Member
      • Aug 2013
      • 78

      Or how plausible is it that Cosmo are using once/twice daily applications from the start of the trials so they can sell it for more usage to increase sales once its marketed? haha

      Comment

      • yan
        Senior Member
        • May 2013
        • 156

        Originally posted by adam k
        Or how plausible is it that Cosmo are using once/twice daily applications from the start of the trials so they can sell it for more usage to increase sales once its marketed? haha
        Haha I have no idea... But we will for sure find out through trial & error. Same as with fin, people found out that even a very small dose can maintain..

        Comment

        • lilpauly
          Senior Member
          • Feb 2012
          • 1084

          "My impression of Kanes CB is that it is ultra pure, compared to the stuff I was using.



          Ive been using it for a couple of weeks now, and everything feels just like CB. No sides at all, and a powerful numbing of the scalp when applied". gk wh has used cb for over 2 years

          Comment

          • hellouser
            Senior Member
            • May 2012
            • 4419

            I got my CB from Kane today, 2grams in total with another 4 grams coming in later on from another source. If used at 10mg/day it would last me almost two years (6000mg / 10 = 600 applications). I'm gonna be using about 15mg/day most likely at 1.5ml per application, at a 10% concentration. I want to make sure I'm protecting my ENTIRE head from DHT hence the 1.5ml but also create regrowth at the hairline and HOPEFULLY fill in the corners.

            First things first;

            Payment with Kane went fine. Cost was $450 with shipping for only 2 grams. Payment was made through Western Union at a kiosk and then provided Kane the MTCN number via email. CB was shipped the next day and CB arrived in under a week, a day ahead of schedule actually, was supposed to arrive tomorrow according to the tracking number. I'm happy.

            Packaging looks like this:



            Opened up and theres another small package inside:



            Opening up the smaller package lead to this:



            I put this away for a few hours (in the freezer) and did more reading on wounding and all that. So now, lets get dissolving!

            The setup and CB, which arrived in an airtight silver pouch:



            As you can see the CB powder is in another small zip lock bag. Up close you can see the refined powder:



            Again, the CB powder is provided in ANOTHER zip lock bag (looks like Kane tries pretty hard to keep it airtight)



            Here's the CB in raw form in the bag:



            So for my first batch I'm going to premix about 50mg of it in 2ml of ethanol with 2ml of propylene glycol for a total of 4ml. Therefor the 50mg in 4ml makes it a 12.5% concentration. A little below my desire 15% target, but it should do.



            Here's the CB completely exposed on my digital scale:



            I'm first going to use an Ethanol/PG vehicle, I'll try Oleyl in the coming days. However, the next photo is the CB in my really small glass jar which holds about 8-9ml total. In this photo, the CB has only been in the Ethanol (Everclear, 95%) for about 15-30 seconds and its ALREADY dissolving:



            Here's the CB in the ethanol from outside the jar:



            And after a 5-10 second light shake, the CB has dissolved COMPLETELY:



            I gotta say, this stuff dissolves even faster than my RU58841. It looks pure as the driven snow.

            I hope this helps!

            Comment

            • clandestine
              Senior Member
              • Aug 2011
              • 2002

              hellouser; incredible post.

              Sorry if you've mentioned, but what vehicle are you using?

              Comment

              • hellouser
                Senior Member
                • May 2012
                • 4419

                Originally posted by clandestine
                hellouser; incredible post.

                Sorry if you've mentioned, but what vehicle are you using?
                I'm first going to try ethanol (everclear) with PG in a 50/50 mix. I've used 49mg in total as you can see on my scale. I dumped that into 2ml of ethanol and 2ml of PG, for a total of 4ml which 50mg in 4ml makes a 12.5% concentration. This is slightly above Cosmo's 1% concentration which gave incredible results.

                I've got Oleyl as well, I'll try that in a few days, see how it goes with itching and shedding.

                Comment

                • DanWS
                  Member
                  • Jul 2013
                  • 68

                  Terrific pics hellouser! Will you be using a dropper to apply the solution or will you be doing it another way? Please keep us updated... any chance you could make a separate thread to regularly document your progress?

                  Comment

                  • hellouser
                    Senior Member
                    • May 2012
                    • 4419

                    Originally posted by DanWS
                    Terrific pics hellouser! Will you be using a dropper to apply the solution or will you be doing it another way? Please keep us updated... any chance you could make a separate thread to regularly document your progress?
                    Yup, I've already got an RU/CB/Minoxidil etc) thread going. I've somewhat dropped RU so the results going forward will be attributed almost exclusively to CB and Dermarolling/Wounding and Minoxidil. Nothing more. No more systemic effects from RU (if I had any) and no Finasteride. Fvck Merck and Fvck Finasteride! Its a GOOD day!

                    And yes, I'm using a dropper, the same one as in my RU Guide/Tutorial thread.

                    Comment

                    • UK_
                      Senior Member
                      • Feb 2011
                      • 2691

                      Hellouser, another great post!

                      You could bump it up to 60mg to get the full 15% later on I guess, but I think 12.5% should be okay considering you're also on RU.

                      What device(s) are you going to use to apply the CB to the scalp? I heard you really need good scalp contact with this stuff.

                      Comment

                      • Westonci
                        Senior Member
                        • Feb 2010
                        • 251

                        Hellhouse your the man!

                        Keep up the good work!

                        Comment

                        • adam k
                          Member
                          • Aug 2013
                          • 78

                          Just got into the office and seen this. Absolutely great stuff Hellouser, you are the man! And brilliant pictures also. From the pictures I can see the CB appears to be of a very good quality (crystalline and shiny). It is also promising to see that it dissolved very quickly in ethanol.

                          Again great post!

                          Comment

                          • adam k
                            Member
                            • Aug 2013
                            • 78

                            Guys regarding the 12.5% concentration. How are you working this out?

                            Comment

                            • StayThick
                              Senior Member
                              • Oct 2012
                              • 624

                              Hellouser: Another great write-up. Your contribution on this forum and helping others with these experimental treatments is amazing. Thanks brotha.

                              It looks like you are utilizing the same vehicle as Iron Dragon at the moment. Although I do not know how pure there CB is.

                              Haven't you already tried CB from Kane in the past but the wrong form?? Correct me if I am wrong. I'm also thinking about pulling the trigger on this as well. It's this and the GF's that have me excited at the moment.

                              Thanks for breaking it down man.

                              Comment

                              • Jens1986
                                Junior Member
                                • May 2013
                                • 24

                                @Hellouser how often will you apply the 12.5% CB?

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