Dermarolling Community Trial

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  • goldbondmafia
    Senior Member
    • Oct 2011
    • 406

    Originally posted by chimera
    Dude, in ebay you can find dermarollers for like $9 or so.
    what if some jackass decided to sell a used one? I don't trust ebay on buying shiet like this or technology lol

    Comment

    • john2399
      Senior Member
      • Jan 2012
      • 521

      Originally posted by TO YOUNG TO RETIRE
      nooooooooooooooooooo no no no no stop and restart it now. it is not about minox absortion BUT

      minox property elevating pgd2 while the wound heals.


      please do it correctly, we dont know that ketoconazole 2% does the same
      Arent you the one that said i dont use minox? So i guess your back on it for the study?

      Comment

      • bigentries
        Senior Member
        • Dec 2011
        • 465

        Originally posted by goldbondmafia
        what if some jackass decided to sell a used one? I don't trust ebay on buying shiet like this or technology lol
        Doubtful, since they come packed and supposedly "sterilized"

        I'm sterilizing mine first in boiling water, then dipping it in alcohol, and then letting it sit for 20 minutes in a betadine solution

        Comment

        • clandestine
          Senior Member
          • Aug 2011
          • 2002

          Originally posted by bigentries
          Doubtful, since they come packed and supposedly "sterilized"

          I'm sterilizing mine first in boiling water, then dipping it in alcohol, and then letting it sit for 20 minutes in a betadine solution
          Where do you buy betadine?

          Also, I remember it mentioning betadine and saline(?) or something?

          Comment

          • bigentries
            Senior Member
            • Dec 2011
            • 465

            Originally posted by clandestine
            Where do you buy betadine?

            Also, I remember it mentioning betadine and saline(?) or something?
            I guess they use saline solution because it is sold sterile, it is sometimes used to wash wounds

            Betadine is povidone-iodine, as far as I know most solutions are sold over the counter

            Comment

            • clandestine
              Senior Member
              • Aug 2011
              • 2002

              Originally posted by bigentries
              I guess they use saline solution because it is sold sterile, it is sometimes used to wash wounds

              Betadine is povidone-iodine, as far as I know most solutions are sold over the counter
              Okay, thanks bigentries.

              I ordered 1.5mm derma roller today, and will be starting Minox when it arrives in a couple weeks.

              Comment

              • Tracy C
                Senior Member
                • Sep 2011
                • 3083

                Originally posted by goldbondmafia
                I am wondering this same thing. Does it last for 3 months if its used daily or weekly?
                When the needles are dull, it's time to get a new one. Maybe it's about three months if it is used daily - maybe a lot longer if it's used weekly. I am betting the three months is based on daily use since Dr. Roller's instructions are to use it daily.



                Originally posted by goldbondmafia
                I want to get a dermaroller but if they cost $40 every 3 months then im not so sure.
                I bought a generic one from Amazon.com. It was somewhere around $10.00 (US) with shipping give or take a few bucks.



                Originally posted by goldbondmafia
                what if some jerk decided to sell a used one? I don't trust ebay on buying stuff like this or technology lol
                Don't blame you there. I would not risk buying a used one either.



                Originally posted by clandestine
                Where do you buy betadine?
                It is inexpensive and readily available anywhere and everywhere bandages and other first aid supplies are sold.

                Comment

                • goldbondmafia
                  Senior Member
                  • Oct 2011
                  • 406

                  Originally posted by Tracy C



                  I bought a generic one from Amazon.com. It was somewhere around $10.00 (US) with shipping give or take a few bucks.
                  do you have the link???

                  Comment

                  • Tracy C
                    Senior Member
                    • Sep 2011
                    • 3083

                    Originally posted by goldbondmafia
                    do you have the link???

                    Comment

                    • brooks1089
                      Junior Member
                      • Nov 2012
                      • 12

                      I have relatively long hair with loss at the temples. I plan to target my temples, but was wondering if it would be beneficial to roll over my existing hair for future maintenance/added thickness? Basically, can you roll over scalp that isn't bald? Thanks guys and good luck!

                      Comment

                      • hellouser
                        Senior Member
                        • May 2012
                        • 4419

                        I've been reading more about the dermarolling method in regards to the wounding theory from follica, I think theres a lot more to explore but I think it NEEDS to be pointed out that we're very, VERY close to finally cracking it. We just need to keep pushing experimentation with wounding of all sorts of devices. Dermarolling with some wounding with 1.5mm microneedles most likely wont get us anywhere near NW0 but it should help. I think we need to wound more. One member on another forum pointed out this:

                        For Follica style wounding you need a wound that is deep enough to remove the epidermis and reach the dermis. It has to large enough so that it can't close on itself. The skin faces a decision, "Do I become a follicle or do I become skin?". By promoting the correct molecular signals, the idea is that we can push the intrafollicular epithelial stem cells (Not HF bulge cells btw). Two are known to upregulate this process - Wnt and FGF9.
                        Which is more or less what mitosis is: cell splitting, but not actually splitting cells in half, but the cells actually replicate themselves. If you cut yourself, cells in your skin should multiply to cover up the damaged area. But here's the problem: we're not doing enough of that at the follicle level!! All we're doing is making small little pricks. I've got a feeling that we need to TRICK our body into making it think it needs to create skin *AND* follicles. Those follicles will probably only replicate where existing terminal hairs are, going back to my observation that hair regrowth always happens in areas closer to existing follicles as those follicles that produce terminal hairs can emit split cells that can replicate their own hair. Which perhaps its why a bald spot is NEVER filled in completely on any treatment, but only tightened up.

                        I'm sure whatever growth factors we throw at the wounded area will help this, for example the growth factors lilpauly has mentioned from Kane, but safety is key. I'm going to watch *very closely* what happens with the guys trialing this... this could be some SERIOUS SHIT finally.

                        This is kind of, KIND OF more exciting than Aderans news before they got their funding pulled.

                        Comment

                        • Tracy C
                          Senior Member
                          • Sep 2011
                          • 3083

                          Originally posted by brooks1089
                          Basically, can you roll over scalp that isn't bald?
                          That's what I plan to do and I'm a girl so I have long hair. I was concerned about my hair tangling up in the roller but I think I have a solution. I can't try it out till my roller arrives though.

                          Look up how wigs are made on Youtube. See how the wig maker puts plastic wrap on her head. That should work to keep hair from getting tangled up in the roller.

                          Comment

                          • gainspotter
                            Senior Member
                            • Aug 2013
                            • 135

                            So from what other just completed my first roll, it is very uncomfortable, especially at the temples, but I don't care about that.
                            From what I've been reading it sounds as though we do need to roll firmly to wound deep enough so the cells can repair. This must mean no blood is not good enough.

                            Comment

                            • hellouser
                              Senior Member
                              • May 2012
                              • 4419

                              Originally posted by gainspotter
                              So from what other just completed my first roll, it is very uncomfortable, especially at the temples, but I don't care about that.
                              From what I've been reading it sounds as though we do need to roll firmly to wound deep enough so the cells can repair. This must mean no blood is not good enough.
                              Yup, mitosis at the follicular level doesn't happen and therefor, no hair. Perhaps elevated levels of WNT may stimulate growth but not to the degree we would ideally want (full NW7 to NW0).

                              Time will tell

                              Comment

                              • Tracy C
                                Senior Member
                                • Sep 2011
                                • 3083

                                Originally posted by gainspotter
                                This must mean no blood is not good enough.
                                Just a reminder that the methodology in the pilot study was to roll firm enough to achieve mild erythema. Erythema is defined as abnormal redness of the skin due to capillary congestion. It does not mean to break through the skin enough to cause bleeding. Just say'in...

                                Comment

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