So how close are we to a new 'cure'

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  • KO1
    Senior Member
    • Jan 2012
    • 805

    #31
    Originally posted by TravisB
    http://www.replicel.com/wp-content/u...ts_Dec2012.pdf

    Here Replicel wrote that their procedure has potential to become PERMANENT solution for hair loss.

    So it means that maybe effects of the treatments will not diminish in time

    How? The native DP cells are still sensitive to androgens. This also does nothing to address the progenitor cell deficit.

    Replicel has never even demonstrated that they can generate new follicles, the most I expect them to do is revitalize miniaturized follicles.

    If the above is the case, then you will still need finasteride for good results.

    Comment

    • sausage
      Senior Member
      • Jan 2012
      • 1063

      #32
      Even if Replicel can create new follicles - can they survive the attack of DHT?

      Comment

      • hellouser
        Senior Member
        • May 2012
        • 4419

        #33
        Originally posted by sausage
        Even if Replicel can create new follicles - can they survive the attack of DHT?
        Likely, the cells will be taken from a patients DHT-Free zone.

        Comment

        • sausage
          Senior Member
          • Jan 2012
          • 1063

          #34
          Originally posted by hellouser
          Likely, the cells will be taken from a patients DHT-Free zone.
          You know what will happen, as soon as they slice my head open in the surgery room someone will announce a cure has been created and I'll be shouting "SEW ME BACK UP"

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          • hellouser
            Senior Member
            • May 2012
            • 4419

            #35
            Originally posted by sausage
            You know what will happen, as soon as they slice my head open in the surgery room someone will announce a cure has been created and I'll be shouting "SEW ME BACK UP"
            I don't think Replicel's method is that intense. Aderans I heard is supposed to take a 1cm x 1cm sample though.

            Comment

            • sausage
              Senior Member
              • Jan 2012
              • 1063

              #36
              Originally posted by hellouser
              I don't think Replicel's method is that intense. Aderans I heard is supposed to take a 1cm x 1cm sample though.
              no, i mean when I go for a hair transplant....as I am having it done a proper cure will probably be announced knowing my luck.

              Comment

              • hellouser
                Senior Member
                • May 2012
                • 4419

                #37
                Originally posted by sausage
                no, i mean when I go for a hair transplant....as I am having it done a proper cure will probably be announced knowing my luck.
                Well, if you want results NOW, I'd say go for it. But its a safe bet nothing will be out for at least another year. 2 years imo is the earliest. But if Aderans got up to speed next year could be possible, and if SkinMedica didn't have shitheads at their company, their failed lawsuit would have enable Histogen to release a product by now.

                Comment

                • KO1
                  Senior Member
                  • Jan 2012
                  • 805

                  #38
                  IF they create new follicles, I suspect yes, they will be DHT resistant.

                  Comment

                  • Pentarou
                    Senior Member
                    • Apr 2013
                    • 482

                    #39
                    Originally posted by hellouser
                    Your belief is wrong.
                    KO1 is easily one of the most knowledgeable people here, so unfortunately he is most likely right about this. These new treatments are a long way away.

                    Originally posted by hellouser
                    Another reason why finasteride should be a FOOTNOTE in hair loss history.
                    I don't think it will be for a very long time, even when/if CB-03-01 is widely available. I'm well aware of its severe limitations, but it works, and has plenty of data behind it, so it going to be part of the hair loss battler's arsenal for the foreseeable future.

                    Comment

                    • Conpecia
                      Senior Member
                      • Sep 2011
                      • 904

                      #40
                      Originally posted by KO1

                      Finasteride is a great treatment for hairloss, and every man who is losing his hair should seriously consider it, ideally before that hairloss becomes visible. Side effects are overblown and exaggerated, and it remains THE gold standard for treatment, and nothing has surpassed it yet.

                      this is an insult to a lot of guys on this forum. myself included. i'd appreciate it if you just wouldn't speak on stuff you clearly know little about.

                      Comment

                      • Pentarou
                        Senior Member
                        • Apr 2013
                        • 482

                        #41
                        Originally posted by KO1
                        NW3 and below don't need any new treatments. If they can tolerate fin (or Dut or CB) an HT would set them up very well for many years. Someone less than NW3 can't even be noted as balding.
                        Respectfully, I strongly disagree. A NW2 can still look genuinely balding if diffuse, and the existing treatments can do little to thicken their hair. Also, diffuse balders cannot get hair transplants at present. New treatments are sorely needed for low Norwoods, although I do agree with you that unfortunately that won't be any time soon.

                        Comment

                        • KO1
                          Senior Member
                          • Jan 2012
                          • 805

                          #42
                          Originally posted by Pentarou
                          Respectfully, I a disagree. A NW2 can still look genuinely balding if diffuse, and the existing treatments can do little to thicken their hair. Also, diffuse balders cannot get hair transplants at present. New treatments are sorely needed for low Norwoods, although I do agree with you that unfortunately that won't be any time soon.
                          Maybe I just have low standards then.

                          Comment

                          • Pentarou
                            Senior Member
                            • Apr 2013
                            • 482

                            #43
                            Also, don't forget that finasteride doesn't work forever, so even if a NW1 guy with very, very early visible hair loss isn't "cured" by fin no matter how long they take it.

                            Comment

                            • hellouser
                              Senior Member
                              • May 2012
                              • 4419

                              #44
                              Originally posted by Pentarou
                              KO1 is easily one of the most knowledgeable people here, so unfortunately he is most likely right about this. These new treatments are a long way away.


                              I don't think it will be for a very long time, even when/if CB-03-01 is widely available. I'm well aware of its severe limitations, but it works, and has plenty of data behind it, so it going to be part of the hair loss battler's arsenal for the foreseeable future.
                              Vast knowledge or none at all, its a joke to say we're a long way away... whats that supposed to mean anyway, several generations away, as in, not in our lifetime? We *are* close. When in history have we ever been able to create skin and follicles? Lauster's already done it. Case closed.

                              Comment

                              • hellouser
                                Senior Member
                                • May 2012
                                • 4419

                                #45
                                Originally posted by Pentarou
                                Also, don't forget that finasteride doesn't work forever, so even if a NW1 guy with very, very early visible hair loss isn't "cured" by fin no matter how long they take it.
                                It doesn't work for everyone either.

                                Comment

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