Pantostin (Alfatradiol)

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  • Desmond84
    Senior Member
    • Oct 2012
    • 987

    Pantostin (Alfatradiol)

    How do we not know about this? It's been available for many years in Germany!

    __________________________________________________ _________________

    Alfatradiol is a 5α-reductase inhibitor used topically for the treatment of androgenic alopecia (hair loss) in men and women.

    A clinical study performed in Germany seemed to reveal that Alfatradiol may perform well at slowing down or stopping the progression of hair loss whereas minoxidil proved to increase hair density and overall hair shaft thickness.

    __________________________________________________ _______________

    For those that can NOT tolerate Finasteride, they should definitely try this Pantostin! Due to its mechanism of action...it is most probably as effective as Finasteride...

    Furthermore, apart from a slight itching, NO adverse effect has been reported with this drug!!!
  • Jens1986
    Junior Member
    • May 2013
    • 24

    #2
    Originally posted by Desmond84
    How do we not know about this? It's been available for many years in Germany!

    __________________________________________________ _________________

    Alfatradiol is a 5α-reductase inhibitor used topically for the treatment of androgenic alopecia (hair loss) in men and women.

    A clinical study performed in Germany seemed to reveal that Alfatradiol may perform well at slowing down or stopping the progression of hair loss whereas minoxidil proved to increase hair density and overall hair shaft thickness.

    __________________________________________________ _______________

    For those that can NOT tolerate Finasteride, they should definitely try this Pantostin! Due to its mechanism of action...it is most probably as effective as Finasteride...

    Furthermore, apart from a slight itching, NO adverse effect has been reported with this drug!!!
    Have you found more than this one study?

    BACKGROUND:

    Two drugs which are approved for the treatment of androgenetic alopecia in women in Germany were compared with regard to their influence on hair growth.

    PATIENTS AND METHODS:

    Patients were randomized to group I (n = 52) who used 2% minoxidil solution twice daily for a period of 12 months or to group II (n = 51) who used 0.025% alfatradiol solution once daily for 6 months and were then switched to 2% minoxidil solution for months 7-12. Changes in hair growth parameters were determined using the TrichoScan.

    RESULTS:

    Topical treatment with 2% minoxidil solution for 6 months resulted in a significant increase of cumulative hair thickness (p < 0.0001) and absolute hair density (p < or = 0.0025), whereas these parameters of hair growth remained nearly unchanged after 6 months of treatment with alfatradiol solution. Evaluation of the same parameters from month 7 to month 12 demonstrated that 12 months minoxidil treatment resulted in an increasing stabilization (group I). After the alfatradiol –>minoxidil switch in group II a significant increase in cumulative hair thickness (p < 0.0001) and absolute hair density (p < 0.0001) was achieved. Both study medications were well tolerated.

    CONCLUSIONS:

    Treatment with minoxidil can induce an increase in hair density and hair thickness, whereas treatment with alfatradiol results in deceleration or stabilization of hair loss.

    Comment

    • UK_
      Senior Member
      • Feb 2011
      • 2691

      #3
      Where can we obtain this? Any safety issues?

      Fin is the most effective treatment for hair loss.

      Comment

      • TO YOUNG TO RETIRE
        Senior Member
        • Mar 2013
        • 638

        #4


        here uk,

        i want to try it too because i dont have a dht blocking agent i think if it is equal to fin then thats the way to go

        Comment

        • Desmond84
          Senior Member
          • Oct 2012
          • 987

          #5
          Yeah Jens..that's the study I was reading

          UK, can you believe this product has been available for over 10 years and no one knows about it!!! My mind is literally blown?!?!

          This is exactly what everyone have been waiting for...Should members be risking their health using RU and CB sourced from black market without knowing their potential long-term side effects when we have this product sitting right under our nose?

          This might tie everyone over till we get Histogen & CB come to fruition

          Comment

          • Desmond84
            Senior Member
            • Oct 2012
            • 987

            #6
            Originally posted by TO YOUNG TO RETIRE
            http://superhumangear.com/store_wp/s...male-baldness/

            here uk,

            i want to try it too because i dont have a dht blocking agent i think if it is equal to fin then thats the way to go
            Nice find brother

            Let's give this a shot

            Comment

            • Dazza
              Senior Member
              • Jun 2012
              • 264

              #7
              Pantostin was talked about on ************ and HLH awhile back. People jumped from Pantostin to cetirizine as Pantostin was apparently to weak. The threads should still be on those websites if you fancy a read through.

              Comment

              • Jens1986
                Junior Member
                • May 2013
                • 24

                #8
                Originally posted by Desmond84
                Yeah Jens..that's the study I was reading
                So thats the only study out there? I havent found enything else than that one

                Comment

                • Desmond84
                  Senior Member
                  • Oct 2012
                  • 987

                  #9
                  Originally posted by Dazza
                  Pantostin was talked about on ************ and HLH awhile back. People jumped from Pantostin to cetirizine as Pantostin was apparently to weak. The threads should still be on those websites if you fancy a read through.
                  Really! Still worth a shot though and worse comes to worse if you can't tolerate fin and this is not strong enough for you, you can still try taking Fin ONCE A WEEK and apply Pantostin every other day of the week! This way, your sides should be minimal and hair loss should significantly slow down!

                  It's important for ppl to know that there are still options out there as Histogen and other future treatments are still a fair while away and keeping the hair you already have should be your first priority!

                  Comment

                  • Dazza
                    Senior Member
                    • Jun 2012
                    • 264

                    #10
                    Originally posted by Desmond84
                    Yeah Jens..that's the study I was reading

                    UK, can you believe this product has been available for over 10 years and no one knows about it!!! My mind is literally blown?!?!

                    This is exactly what everyone have been waiting for...Should members be risking their health using RU and CB sourced from black market without knowing their potential long-term side effects when we have this product sitting right under our nose?

                    This might tie everyone over till we get Histogen & CB come to fruition
                    You have to remember Des, if this was truely a great thing and worked it would be around the web and doctors would be proscribing this. If something has been around for 10years and still not heard of, that kinda speaks for itself.

                    Comment

                    • UK_
                      Senior Member
                      • Feb 2011
                      • 2691

                      #11
                      Originally posted by Desmond84
                      Yeah Jens..that's the study I was reading

                      UK, can you believe this product has been available for over 10 years and no one knows about it!!! My mind is literally blown?!?!
                      This is exactly what everyone have been waiting for...Should members be risking their health using RU and CB sourced from black market without knowing their potential long-term side effects when we have this product sitting right under our nose?

                      This might tie everyone over till we get Histogen & CB come to fruition
                      I know, it's a similar story for RU58841 - makes me wonder if we're just going round in circles.

                      Comment

                      • Desmond84
                        Senior Member
                        • Oct 2012
                        • 987

                        #12
                        Originally posted by Dazza
                        You have to remember Des, if this was truely a great thing and worked it would be around the web and doctors would be proscribing this. If something has been around for 10years and still not heard of, that kinda speaks for itself.
                        Very true Dazza, and you may be right indeed. Unfortunately the study I read was very minimalistic...reminded me of LOREAL studies which is disappointing...there's no mention of plasma / scalp DHT levels, etc

                        But, it may help some ppl particularly those that are really scared of using fin and that's something in itself I suppose...

                        Comment

                        • Dazza
                          Senior Member
                          • Jun 2012
                          • 264

                          #13
                          Originally posted by Desmond84
                          Very true Dazza, and you may be right indeed. Unfortunately the study I read was very minimalistic...reminded me of LOREAL studies which is disappointing...there's no mention of plasma / scalp DHT levels, etc

                          But, it may help some ppl particularly those that are really scared of using fin and that's something in itself I suppose...
                          absolutely

                          Comment

                          • UK_
                            Senior Member
                            • Feb 2011
                            • 2691

                            #14
                            All of this confusion and fear of taking anti-androgens is resting on the misconceived notion that DHT has no use in the male body, an assertion actually made by Merck in their "2% side effect study" - I'm going state the obvious; if it's existed in the human body for millions of years of evolution then it HAS a ****ing purpose.

                            Comment

                            • Desmond84
                              Senior Member
                              • Oct 2012
                              • 987

                              #15
                              For some reason, pharmaceutical companies gave up on the idea of topical hairloss drugs as soon as Propecia came out!

                              They assumed tablets are so much easier to use and very effective! What they didn't take into account was the fin sides which is why we're in the situation we are today!

                              Cosmo pharmaceutical has finally caught on to that and is trying to get CB on the market. The sad thing is CB-03-01 was discovered in the late 90's...it was shelved since Propecia was assumed to be good enough!

                              Enough of the past though..its just depressing

                              Let's focus on what we can do today!

                              Comment

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