Dr Nigam, my own experience

[534623]

IM..your railway tracks..is half the story..inside the scalp the base of the follicles with the root are splayed out..and not..straight..

Excuse me, but what part exactly of the content of your link ...

http://www.bernsteinmedical.com/hair-transplant/follicular-unit-extraction/pros-and-cons-fue/a-challenge-of-fue/

... concerning follicle splay and how to overcome this problem ...

Right: "The principle behind Follicular Unit Extraction (FUE) is that, in order to avoid this injury, follicular units would not be totally excised (cut) from the scalp, but rather “extracted” or pulled out of the scalp, so that the lower part of the follicles would not be cut off. Figure B (above right) shows the instrument going partially down the follicular unit. Once the upper part of the unit is separated from the surrounding tissue, the entire follicular unit is then “extracted” (pulled out) of the skin."

... don't you understand??

According to Dr. Gho, they don't cut deeper than 2-3 mm to separate just the upper part of the unit from the hair shafts surrounding FOLLICLE tissue (NOT surrounding SKIN tissue as with FUE!), and then they simply pluck/pull out the lower parts of the unit, which include the DP containing follicle bulbs.

even the round fue punch, uses the hair shaft of bundles of follicles as guide..nothing new what hst does with their triple wave fue punch..
lesser the diameter of round punch or triple wave needle/punch(.5mm/.6mm..more the chances of transection..that is what the fue docs want to avoid..to prevent damage to hair bulb..

How do you know how Dr. Gho's invented sharp/blunt combined triple waved needle works??
Can you please take a photo with your own camera/microscope of such an extraction needle?

But let me guess: Dr. Gho invented such a special needle just for fun ...

the picture on your left is after the graft is extracted..not when it is inside the scalp..do not misguide members with dramatic visual presentations..

hmmm, did I say anywhere that Dr. Gho's pic on the left (which you can also find in his published HST study) shows a graft "inside the scalp"???
Even an idiot can see that the pic shows an extracted HST graft.

ahhh, I forgot - you mean it is a rather "straight" graft with rather "straight" follicles and that this graft doesn't show "splayed apart" lower halfs - right?

As long as the grafts are not in such an extreme curved configration in the skin ...

... as you can see this in the pic on the right - "no problem at all" to extract HST grafts even if there is 1) follicle splay in general or 2) the follicles are curved somewhat, as you can see this in the pic in the middle.

oops, sorry, I forgot - I shouldn't "misguide members with dramatic visual presentations" ...

Sorry Dr. Nigam, but I'm not the guy who tried already SEVERAL TIMES to mislead people with PHOTOSHOPED before/after photos!!

[Arashi]

I found a good comparison between Dr. Nigam and Dr. Gho technique in Hair Site website, this clarified everything to me between the hair doubling techniques of these two reputed surgeons.

Its the following:-

"LET US COMPARE THE ONLY TWO HAIR CLINIC IN THE WORLD FOR HOUR DOUBLING / DONOR DOUBLING –

Our friend Dr. Gho’s - Donor doubling & Dr. Nigam Hair Doubling with activated Stem Cells and DP cells:-
H
1G. Dr. Gho bisects the follicular unit and not single follicle longitudinally in Vivo (when the follicle already exist in the scalp), hence it is a blind technique. (As per Dr. Gho’s published paper he himself mentioned there are unsuitable or damaged grafts at the donor area. He bisects using a inner diameter, 0.6 mm triple waved tipped partially blunt FUE punch (he calls it triple wave punch). Since Dermal Papilla is embedded in sub-cutaneous fat cells hence it is unlikely Dermal Papilla cells would be present in the extracted bisected follicular unit or maybe he is able to extract part of Dermal Papilla. As per Dr. Cole’s website Dr. Gho tries to bisect the follicle at the line of Auber which he found difficult and was worried about loss or damage caused to the grafts. Although even if 1/3 proximal that is a root with outer root sheath and 2/3 distal which contains bulge stem cell and part of outer root sheath stem cells, generate hair up to 60% to 70% which has been shown in the earlier studies of Toscani, Rossi, Erjin, Jahoda, Roy and Micali. This also shows that if there is such a partial FUE or transacted FUE with proximal and distal stem cells it can still grow both the bisected follicles. Although the character and diameter of the hair may differ. Remember Dr. Gho is not cutting follicle unit into two but a folliclular unit(refer to his histo slide in his paper and not the picture mentioned in his paper) into two. Kindly refer his article donor hair follicle preservation by partial follicular unit extraction a method to optimize hair transplantation.

1N. Dr. Nigam bisects the hair follicle / follicular unit transversely in vitro under 50x magnification with special fine blades and also collects the spilled out approximately 1000 to 1200 DP cells and injects it back in to the bisected follicles along with autologus activated epithelial and dermal papilla cells, outer root sheath, stem cells through 25 to 50 separately extracted follicular units in Vitro (when the follicle is not existing in the scalp but the cutting is done under microscope with full vision hence there is no chance for unsuitable or damaged grafts). The bisection is done at the particular level on the follicle wherein the Dermal Papilla cells & outer root sheath cells are present in both the bisected parts of the follicle. Due to patent pending neither Dr. Nigam nor Dr. Gho has not mentioned that at what level they bisect the follicle.

2G. Dr. Gho’s technique utilized only preservative media which does not have stem cell or isolated stem cell for boosting and survival of bisected follicle & no growth factor, no stem cells were utilized. Dr. Gho claims in his website that stem cell is been extracted from the donor area and implanted in the recipient area which is false and misleading because bisected follicle unit is extracted and implanted in the recipient area.

2N. Dr. Nigam’s technique involves addition of isolated activated stem cells with growth factors isolated Dermal Papilla cells injections extra cellular matrix and 250 arterial PRP, Epidermal growth factor, follistation,, KGF, FGF and other (can’t disclose all as patent is under process)

3G. Dr. Gho claims that since he keeps the bisected follicular unit in the preservative medium (The medium is composed of the following ingredients: sodium chloride, potassium chloride, magnesium sulphate, sodium phosphate, calcium chloride, glucose, sodium bicarbonate, sodium lactate, sodium pyruvate, human serum albumin, insulin, bis(maltolato)oxovanadium (BMOV) and
a-tocopherol (vitamin E)) of nutritional factors hence this technique should not be claimed as stem cell hair transplant (Because no isolation of stem cell is done in a regenerative lab, hence the technique cannot claim any manipulation of stem cells. Although it is true even in a normal hair fall when a new hair grows it is because of the inherent multiplication of the stem cell present in the hair follicle. Any isolation or multiplication of stem cell is possible only in a FDA or European authority certified lab which our friend Dr. Gho does not have at present.

3N. Since Dr. Nigam has his own Lab he can extract few grafts from the body or from the donor area and isolate stem cell from the grafts, Dermal Papilla and Dermal Sheath cells, plus isolate and cultured with inducible Dermal Papilla cells and inject the solution into both the bisected units so that they are nourished with the required nutrition to develop.

4G. Unfortunately regulation in Europe are very strict for isolation, multiplication, activation of even adult stem cells not to mention embryonic stem cell or allogeneic stem cell, the use of which is legally 25 years away. Hence our dear Dr. Gho has shifted his lab and opened one unit in Indonesia to catch up fast and may be introduced activated stem cells into his present techniques.

4N. Luckily in India for Dr. Nigam research and therapy on adult autologus stem cell with minimal manipulation is legal and cleared by 3 regulatory authorities in India (Dr. Nigam has a clearance from these 3 authorities in India) and since he utilizes the activated stem cells in his medical procedure with monthly follow up with his all patients with a special consent form. Dr. Nigam’s technique is only be legal in few countries as on today across the globe including India.

5G. Dr. Gho has patented his process of longitudinally bisection of donor hair follicle, preservation by partial follicular unit extraction a method to optimize hair transplantation (kindly confirm the same with the patent authority and through his published paper in journal of Dermatological Treatment, 2010, 21:337-349. Since Dr. Gho himself calls his technique partial follicular extraction it is misleading to named it as stem cell hair transplant. This nomenclature of stem cell hair transplant is not usually objected by patent authorities but can be objected very well by European authorities of stem cells because claiming of stem cells therapy or its used is not legal in Europe. The word stem cell for hair transplant can only be used if it is isolated in FDA certified regenerative lab and / or activated and then injected back into the scalp. Unfortunately this is not the case of in Dr. Gho. Hence if this will come to the notice of Stem Cells authority they might take action against it but patent authority will not object for the same. Infact it is the inherent property of the existing stem cells in a hair follicle to denovo on its own to get activated and multiply to regenerate a bisected hair follicle if all the different type of stem cells is present in the bisected the follicle to regenerate a new hair follicle. Dr. Gho bisected graft are minimal outside the scalp by 4 to 5 hrs including 2 hrs in the preservative medium.

5N. Since Dr. Nigam has his own FDA licensed regenerative Lab in Mumbai (the license is already posted on the forum) Dr. Nigam’s Bio-Techs first isolate the adult hair stem cells present in a hair follicle, sorted out by magnetic beading system and then they activate (not multiplied which takes one and half a month) with serum free growth factors within 4 hrs of time and then they inject it into the bisected follicles. This hair doubling has been trademarked in India and Patent application is under process. We believe this is a actual stem cell Hair Doubling. At Dr. Nigam’s we do not keep the follicles outside the scalp for more than 50 min in any of the hair transplant procedure including Hair Doubling.
We make Patient lie-down in a lateral position and one Doctor extract and other Doctor implants the grafts simultaneously (most of the transplant elsewhere are done in supine or prone position where the surgeon has to first extract the graft which takes few hours and then implant the grafts except in DHI technique. We use PRP growth factor and extra cellular matrix to increase the graft survival. We make recipient incisions prior to the extraction of grafts to promote granulation of tissues and minimizing scalp.

6G. Dr. Gho’s technique of Donor Doubling or preservation can transform the NW7 to NW2 in 2 years of time and that also at a very high cost because on an average 1500 grafts can be replicated only after 6 to 7 months.

6N. Dr. Nigam’s technique of Donor Doubling or Hair Doubling are effective because in this technique both the bisected part of the grafts can be implanted at the recipient area hence through this technique NW7 can be transformed to NW2 in 10 – 15 days from the procedure.

7G. The cost and time to transform NW7 to NW2 (10000 grafts) through Dr. Gho’s technique will cost very high (approximately USD $13000 for 2000 Grafts which means US $50000 for 10000 Grafts) and this transformation will take atleast 5 years.

7N. The cost for 10000 Grafts with Dr. Nigam’s Hair Doubling technique for 2000 Grafts in one day is USD $5000 and USD $10000 (All Inclusive) for 10000 Grafts. The total time period required for 10000 Grafts is 10 – 15 days.
You must be wondering that the NW7 patient can donate only 2000 to 3000 follicular unit maximum. We can extract 3000 follicular unit from NW7 and we can double it to 6000 follicular units and can be implanted into the recipient scalp. The Balance 2000 / 3000 grafts can be taken from the body or beard and similarly can be doubled to 4000 /6000 grafts as body hair are single follicular Graft.

8G. Both Dr. Gho is using surrounding tissues with the bisected follicular unit

8N. Dr. Nigam is also using surrounding tissues with the bisected follicle

9G. Dr. Gho is using 0.6 mm inner diameter which means 0.7 mm FUE punch of outer diameter. Although his punch is triple waved tipped, which is partially blunt.

9N. Dr. Nigam uses the same 0.6 mm inner diameter which means 0.7 mm FUE punch.

10G. Blindly longitudinal bisection in vivo has a disadvantage since the hair follicles angles at the skin surface is different from the placement angles of the bottom part of the hair follicle with the root. Hence higher number of transected or unsuitable grafts are possible and it’s a time consuming process

10N. Since at Dr. Nigam’s the bisection of follicle / follicular unit is done under high magnification in vitro which is outside the scalp, negligible chances of transected or unsuitable grafts. Kindly go through Dr. Cole explanation of the same in his post on the forum

11G. Healing of the donor area with Dr. Gho’s technique is also better than traditional FUE.

11N. Healing of the donor area is exceptionally fast in Dr. Nigam’s technique due to the use of activated stem cells, growth factors, isolated DP cells, extra-cellular matrix and PRP. Some of the forum member has already commented that they have not seen such exceptionally fast healing of both donor as well as recipient area with complete healing bring the scalp to the normal state without dot marks.

Challenges for both Dr. Gho & Dr. Nigam:-
Dr. Gho and Dr. Nigam both have to get their documentation of Donor Doubling / Hair Doubling atleast on 5 patients independently by informed and computer skilled consumer or by a independent hair transplant Doctor and / or by independent editor of top credible hair loss forum. Dr. Nigam has already agreed for the above procedure for free of cost in Mumbai and similar response from Dr. Gho is awaited. Both these techniques are promising and can change the hair loss industry in better way before the real Hair Multiplication, Dermal Papilla implantation or macro follicle Organoid hair implantation becomes a reality in next 1 to 5 years as it is the next and may be the final breakthrough in the HT industry for MPB. Neither of their technique can claim multiplication but it can be classified as Donor Doubling & Hair Doubling respectively."

This really is a horrible comparison. The way it was written it surely seems like it was nigams who wrote it ? I disagree with a lot of it. But regardless, i think it makes you look quite bad dr nigams, claiming all kinds of stuff regarding gho while you dont even exactly know what he does and without him being able to defend himself. I personally think this makes you look unprofessional. Why not focus on your own technique. If its as good as you claim it is then why try to attack gho ? All his patients will come to you anyway if youre as good as you claim you are. Hence act a bit more profesional.

[drnigams]

Dear im,
Your replies are helping me to ..clear your own contradictions..

1)Dr HARRIS INTRODUCED THE TECHNIQUE OF 3 STEP FUE,WHEREIN..
first a sharp punch with lesser diameter is used to create the wound hole..than ,the skin opens up wider..now in the second step..the blunt punch is used with wider diameter..to avoid transection..the wider punch goes 2/3 deep and than the follicle/graft is tweezed out..this process is called..3step fue..and is used by most of the top fue surgeons.routienly..

so, when you talk about that hst goes upto 2/3mm deep and plucks the follicle..is no different from fue..

2)Till today hst and you have been saying that you extract the follicle longitudnally as abiseted folilcle..which is seen by no body ,except in graphics,
not even in the left pic you provided..

Today for the first time you said..hst also bisects the graft horizontally..in addition to longitudnally..(contradiction).

Till before this post..you were claiming that,you take the help of hair shaft,like railway tracks and go longitudnally and extract grafts ..which is also shown in the HST WEBSITE..

BUT CONTRADICTORY TO YOUR STATEMENT,now you say that you go deep ONLY upto 2/3mm IN THE SKIN(WHERIN THE FOLLICLE BULB LIES AT APPROX.4.12MM DEPTH FROM SKIN SURFACE)
and pluck the graft..which means you are removing part of the graft....by plucking the graft.. amazing and precise way to bisect..wow..!!
such a bisection by plucking the graft(which is undesirable and happens accidently in fue).... is called transected fue by the surgeons..which you call hst graft..

and how do you do longitudnal and horizontal..bisection invivo..when your rocket science,triple wave needle..does not go deeper than 2/3mm into the skin..that means ..you actually do longitudnal/horizontal bisection...by plucking and pulling the graft...wow..that is amazing.. precise..

FUE surgeons use the pull to avoid injury to the bulb..and you use the pull to bisect the graft...wow...!

3)Surgeons across the world, mention that the whole graft and especially the bulb..should be covered with surrounding tissue..
hence they say.. in fut grafts..their is surrounding tissue protection around bulb..the quality and survival of the graft is better in fut grafts..than fue..as in fue the bulb is not much protected with the sorrounding tissue and hence prone to damage....

Kindly check TOM'S graft(WHITE COTTON LIKE SORROUNDING TISSUE AND HST GRAFTS(WITH MINIMAL TISSUE) ..WHO HAS MORE SURROUNDING TISSUE FOR BETTER SURVIVAL OF GRAFTS..

If you are not taking sorrounding dermis tissue..it is bad for graft survival..and if you are not taking even follicle tissue..it is worse for the grafts survival..

4)Majority of the grafts are splayed at the bottom half...the grafts are bunched together till middle of their depth in the skin..and than they start splaying..especially in doubles,triples,quadriplets..
even in single graft the angle is not perpendicular contrary to your graphic claim..there is mostly some angular deviation even in singles..

This are the two main reasons..why fut is still being performed..
1)the angulation of grafts at the root in the dermis/fat layer..blind fue makes it prone to higher transection.hence advisable to use wider punch..
2)as the graft is plucked with the bulb..it does not have sorrounding dermal tissue protection which can lead to damage to the bulge on exposure and during extraction ,leading to lesser yield/hair diametre...

Kindly post all the pics from the link i posted..it will help me contradict your own theory....


!

Excuse me, but what part exactly of the content of your link ...

http://www.bernsteinmedical.com/hair-transplant/follicular-unit-extraction/pros-and-cons-fue/a-challenge-of-fue/

... concerning follicle splay and how to overcome this problem ...

Right: "The principle behind Follicular Unit Extraction (FUE) is that, in order to avoid this injury, follicular units would not be totally excised (cut) from the scalp, but rather “extracted” or pulled out of the scalp, so that the lower part of the follicles would not be cut off. Figure B (above right) shows the instrument going partially down the follicular unit. Once the upper part of the unit is separated from the surrounding tissue, the entire follicular unit is then “extracted” (pulled out) of the skin."

... don't you understand??

According to Dr. Gho, they don't cut deeper than 2-3 mm to separate just the upper part of the unit from the hair shafts surrounding FOLLICLE tissue (NOT surrounding SKIN tissue as with FUE!), and then they simply pluck/pull out the lower parts of the unit, which include the DP containing follicle bulbs.



How do you know how Dr. Gho's invented sharp/blunt combined triple waved needle works??
Can you please take a photo with your own camera/microscope of such an extraction needle?

But let me guess: Dr. Gho invented such a special needle just for fun ...



hmmm, did I say anywhere that Dr. Gho's pic on the left (which you can also find in his published HST study) shows a graft "inside the scalp"???
Even an idiot can see that the pic shows an extracted HST graft.

ahhh, I forgot - you mean it is a rather "straight" graft with rather "straight" follicles and that this graft doesn't show "splayed apart" lower halfs - right?

As long as the grafts are not in such an extreme curved configration in the skin ...

... as you can see this in the pic on the right - "no problem at all" to extract HST grafts even if there is 1) follicle splay in general or 2) the follicles are curved somewhat, as you can see this in the pic in the middle.

oops, sorry, I forgot - I shouldn't "misguide members with dramatic visual presentations" ...

Sorry Dr. Nigam, but I'm not the guy who tried already SEVERAL TIMES to mislead people with PHOTOSHOPED before/after photos!!

[534623]

IM..your railway tracks..is half the story..

Okay - if you don't like my "dramatic visual railroad presentations" and if you would like to see the whole story - here is the whole story...


So now you can see a combined Dr. Bernstein (FUE)/IronMan (HST) presentation.

[drnigams]

Arashi..if im keeps posting..misleading theories..i will have to clarify..

don't you think..it is better to clarify and give my opinion,when asked for..from the members..

i am not attacking in person..but debating the technique..only when asked for.

are my theories not contradicted..did i raise objection .... that my techniques should not be questioned..

i am not interested in negativity..but im keeps coming to the thread..and if i am silent..which may seem ..i agree to him or have no explanation..
i bdo not feel it is unprofessional to scrutinize wrong claims..bringing to light any misleading claims...does not mean seeking patients..

[gc83uk]

Dr Nigam,

Are you familiar with this set of questions and answers with Dr Gho back in 2005:

http://www.baldnessbattlers.com/JBInterviewGho.htm

I'd be interested to hear your thoughts on what you've read there.

[didi]

Okay - if you don't like my "dramatic visual railroad presentations" and if you would like to see the whole story - here is the whole story...


So now you can see a combined Dr. Bernstein (FUE)/IronMan (HST) presentation.

and what do we see here?



Labeled as singles by by hasci experts, how can you have one bulb and one bulbless hair and call it single when it was originally double?



answer is this

[didi]

and this is what Gho is saying, needle goes straight though the middle of bulb

Very different than what IM is claiming in his dramatic picture

[drnigams]

gc,
yes,on hairsit..i discussed this interview..with the forum member..james bond and others..

1) again the same old story..preservation media..multiplies stemcells ...i will have to explain the whole story again..no preservation media on the planet earth can multiply stemcells..they can only keep the grafts alive...for few extra days..

All the researchers , study effects of various compounds on intact hair follicle IN THE LAB..IN THE DIFFERENT TYPES OF CULTURE MEDIUM..

If the soaking in culture medium..could create new hair,or activate stemcells,or multiply stemcells....
than mpb would have been cured by now..

no further need for biotech labs,world congress on hair/stemcell research....

One has to first isolate or extract the stemcells from different types of cells in a hair follicle..in the lab under CO2 incubation, at specific temperatures,with enzymatic digestion...by loosening up the cell membrane,opening potassium channels..etc...

once isolated..these are progenitor stemcells... stemcells are confirmed with their respective markers like cd200,cd34,k19 etc...and kept for atleast 6 weeks to have significant cell division..with multiple passages...to have any significant dosage of active stemcells to have any effect on hair generation or multiplication...

I hope you understand now,that soaking in illusionary preservation media..if it could have multiplied stemcells or activated them..mpb would have been cured..and all ht surgeons would keep their extracted grafts in the culture medium and multiply stemcells....

just google and find out..isolation and culture of hair follicle stemcells ..you will yourself..than it will make you understand better..that stemcells do not get activated or multiplied in keeping for 2 hours in preservation media...

RALF PAUS..LAUGHINGLY SAID..AT WCHR,UK..THAT SURGEONS COME TO HIM..AND ASK IS THERE ANYTHING THEY CAN HAVE TO KEEP THE GRAFTS IN THE MEDIA..FOR HAIR MULTIPLICATION..

2)AGAIN,ONLY DONOR REGEN PICS SHOWN FOR EXPLANATION..NO PIC OF RECIPIENT SHOWN OF THE SAME PATIENTS OTHER BISECTED HALF..

3)IN QUESTION NUMBER 4,HST SAYS..PARTIAL DONOR REGROWTH.... IN FOLLICULAR MULTIPLICATION TECHNIQUE...

NOW GC PLEASE EXPLAIN TO ME ,WHEN YOU CAN SEE INTACT PARTIAL FOLLICLE WITH IT'S BLOOD SUPPLY..WHY WILL NOT BE NEAR 100% DONOR REGROWTH...WITH PARTIAL FOLLICULAR UNIT EXTRACTION..WITH ITS BULB AND BLOOD SUPPLY INTACT..ALL MY INVIVO SHOWS THE SAME..JUST PLUCK YOUR HAIR ..LIKE AN EYEBROW PLUCK..THE EYEBROW GROWS BACK..NO ROCKET SCIENCE ..REQUIRED TO EXPLAIN THIS TO A LAYMAN...

3)Compare yourself,the diagrammatic pics they show..and actual grafts in the petri dish...why these two should be different...there should not be the transected follicles seen in their doubles..as they claim they go deep(as against im's claim that they go 2/3mm deep,and than pluck)nd bisect longitudnally...the follicle..and not the follicular unit(if they are bisecting follicular unit,longitudnlly,than it is follicle splitting..)

4)When an fue /fut graft is extracted,it carries with it,INHERENT..dermal sheath,outer root sheath,sorrounding tuissue of follicle and dermis..nothing new..but hst says ,since we carry the tissue(dermal sheath/outer root sheath) around the graft, (which infact i.e the dermal sheath etc. is inherently extracted with fue/fut grafts anyway..)
this means we carry stemcells of the follicle in our grafts...and they go one step further in their claims..on their website...that infact ,this process is called not graft extraction..but stemcell extraction and stemcell implantation...what can i say now....
LOOK AT IM'S EXPLAINATION OF HST GRAFT BISECTION..THAN A DIFFERENT PICTURISED EXPLANATION IN THE INTERVIEW/WEBSITE..AND DIFFERENT GRAFTS SEEN IN PETRI DISH....

Dr Nigam,

Are you familiar with this set of questions and answers with Dr Gho back in 2005:

http://www.baldnessbattlers.com/JBInterviewGho.htm

I'd be interested to hear your thoughts on what you've read there.

[gc83uk]

Forgive me Dr Nigam, but I found your comments almost impossible to comprehend in your previous comment.

As for Ghos storage medium, in my mind this is just to keep the grafts alive and that is simply it vs the old fashioned saline solution. I seriously doubt that hairs are multiplying in the petri dish, I'd also be surprised if anybody believed this, so I don't understand why this nonsense keeps being brought up.

The way I see it, when hairs are transected with missing bulbs like the pictures in this thread then it will obviously not grow in the recipient.

To summarise, if a 2 hair FU is extracted from the donor and there is a missing bulb (now becomes a single HST graft), it will be implanted and expected to grow as a single graft in the recipient. However the good news is the bulb that was missing will of course still be in the donor and grow as normal, but more importantly the bulb that was taken to be implanted in the recipient will also regrow in the donor area because there is still the surrounding cells which will allow the bulbless part of the graft to regrow. So in effect the 2 hair FU will regrow and a 1 hair graft will grown in the recipient. So in this scenario there is a net increase of 1 hair.

So not quite doubling, but turning 2 hairs into 3 is an improvement on FUE.

This is just my opinion!

[Arashi]

Forgive me Dr Nigam, but I found your comments almost impossible to comprehend in your previous comment.

As for Ghos storage medium, in my mind this is just to keep the grafts alive and that is simply it vs the old fashioned saline solution. I seriously doubt that hairs are multiplying in the petri dish, I'd also be surprised if anybody believed this, so I don't understand why this nonsense keeps being brought up.

The way I see it, when hairs are transected with missing bulbs like the pictures in this thread then it will obviously not grow in the recipient.

To summarise, if a 2 hair FU is extracted from the donor and there is a missing bulb (now becomes a single HST graft), it will be implanted and expected to grow as a single graft in the recipient. However the good news is the bulb that was missing will of course still be in the donor and grow as normal, but more importantly the bulb that was taken to be implanted in the recipient will also regrow in the donor area because there is still the surrounding cells which will allow the bulbless part of the graft to regrow. So in effect the 2 hair FU will regrow and a 1 hair graft will grown in the recipient. So in this scenario there is a net increase of 1 hair.

So not quite doubling, but turning 2 hairs into 3 is an improvement on FUE.

This is just my opinion!

I've also always understood the 'preservation medium' to be a medium for just that: to keep the grafts from dying while outside the body. The way I understand how his technique works is simply that he transplants part of the grafts, including some tissue, which always contains stem cells (cause these stem cells are located next to the graft). One part of the graft remains in donor, other part gets transplanted to recipient, both parts have access to stem cells and both parts try to regenerate themselves with stem cells, it's just how the human body works. So Gho doesn't even have to understand the complex signalling, he just takes advantage of what human nature already does: repair wounds.

[Arashi]

But Dr Nigam, haven't you read the paper Dr Gho has written in the British Journal of Science ? If you disagree with what's in there, then why don't you write a paper too and send it to them ? I think it would be much more effective than writing some stuff here on these forums, wouldnt you agree ? Cause:
1) Gho can't defend himself here
2) Pretty much nobody here is a professional dermatologist so we just lack the knowledge to agree/disagree to what you or Gho is saying
3) The British Journal of Dermatology on the other hand is a peer reviewed academic magazine. If they approve of what you're saying, then we know that at least it's not BS
4) Gho can then go ahead and write another article there too if he wants.

The biggest problem with your theories here regarding Gho is that we have seen for example the cases from GC83UK. Although we still don't know exact regrowth numbers, at least we DO know that regrowth is happening. His donor was very bad to begin with, he's gotten 3 transplants already and is going back for the 4th. Something that would have been impossible if regrowth wasn't even happening at all.

[gc83uk]

But Dr Nigam, haven't you read the paper Dr Gho has written in the British Journal of Science ? If you disagree with what's in there, then why don't you write a paper too and send it to them ? I think it would be much more effective than writing some stuff here on these forums, wouldnt you agree ? Cause:
1) Gho can't defend himself here
2) Pretty much nobody here is a professional dermatologist so we just lack the knowledge to agree/disagree to what you or Gho is saying
3) The British Journal of Dermatology on the other hand is a peer reviewed academic magazine. If they approve of what you're saying, then we know that at least it's not BS
4) Gho can then go ahead and write another article there too if he wants.

The biggest problem with your theories here regarding Gho is that we have seen for example the cases from GC83UK. Although we still don't know exact regrowth numbers, at least we DO know that regrowth is happening. His donor was very bad to begin with, he's gotten 3 transplants already and is going back for the 4th. Something that would have been impossible if regrowth wasn't even happening at all.

I completely agree with this mate, but I don't think Dr Nigam 100% understands what Dr Gho is doing (No offense intended to Dr Nigam).
Challenging the paper without knowing e.g the % per ingredient in the pres medium is impossible surely.

[Arashi]

Challenging the paper without knowing e.g the % per ingredient in the pres medium is impossible surely.

And this is EXACTLY my point ! I think it not only makes no sense to do it, it also makes Dr Nigams look bad. Normally a doctor doesn't speak bad of another doctor anyway. Nigams says he kind of is forced to do it because of Ironman, but come on dr Nigams, if Ironman bothers you, then fight back to Ironman, but what does that have to do with Gho ?

[KO1]

I don't think there is any point in Dr Nigam trying to refute Gho. Who is Gho anyways that he must be refuted? Gho is barely involved in modern hair research, and is simply not in the picture.