Dr Nigam, my own experience

[Desmond84]

Oh also Tom could you please take a lot of photos NOW or in the next few days, so we can see if these injections had any effect in the next few months! And btw I didn't get to say this before, thank you so much for all your efforts brother...I have a lot of respect for ppl like you and Boldy who are actually trying actively to find a cure rather than sitting at home sobbing over this mess!

I'm wishing you the very best and really hope these treatment protocols work out

Looking forward to seeing your mohawk brother

[Desmond84]

Desmond84, what do you think about the safety of Dr. Nigams procedure?

In terms of safety, there are TWO concerns:

1) Safety of DP cells expanded in culture and reintroduced in the dermal layer: as Mario mentioned the 2D DP expansion method has been tested in humans by Intercytex and Aderans since 2004 with no serious adverse events reported and both companies managed to finish both their Phase 1 and 2 trials without any major concerns...which is GREAT NEWS The jury is still out there on the 3D spheroidal method

2) Safety of Dr Nigam's DP expansion: This is where Boldy's expertise come into play...when dealing with Biological therapies 60% of a therapy's efficacy and risk of side effects is based on method of manufacture! As long as we can be assured by Boldy (and hopefully other Doctors such as Dr Cole) that Dr Nigam's laboratory is state of the art with up to date GMP and GLP practices then we can be almost certain that there is NOT much risk of doing it in Mumbai! The "Good Manufacturing Practice" and "Good Laboratory Practice" guidelines have just been updated to include manufacturing of biologicals which is a very complex process, where slight changes in storage or culturing method may lead to a completely different final product.

About the patent i've linked i have noticed that has been registered more than 2 yrs ago under Alvi Armani who is (was?) a HT surgeon and show a complete temporal restoration (in terms of quantity, i don't know about density) so why they don't have never offered to their patients? Maybe the HT business is more profitable, we should remember before start complain about Nigam every time

How sad is this! But don't worry guys, if the science is right and it actually works, it will happen one way or another...

Indeed mari0s, the thing is, why would you invest, and take ricks, if you have already a successful running clinic? regarding arvid, he has a very successful clinic line, nigams, has already 2 full clinics with 6-8 patients per day, however he still invests allot in improving the current techniques.

People don't seem to see this fact.

3d culture is to time consuming(the process would be approximately 8-10 weeks per patient), calculated per hour, its much smarter to make money with a HT... very sad that. the business are there just for money.. something we should not forget.


also, not to forget, in india you wont have the regulations issues, that you have in europe/us.

I have received my pics from nigams, and I think I will have time today to make my post, about my temporal hairline restoration, we used some different approach, than what he used to its a experiment that looks good so far.


Boldy

Dr Nigam's efforts should be watched very closely...it is the most interesting story to happen in the past 5 years at least!

I personally love his charismatic attitude...time will also tell if his efforts will work...the 3D DP culturing combined with beard DP culturing is a radical idea that definitely points to the fact that he's here to be taken seriously and wants to offer something better!

And I say, good on this guy...let's give him a chance and not de-fame him before he even gets a chance to produce the results...

July 2014 will be make or break for a lot of these upcoming treatments such as Replicel, CB-03-01 and most probably Dr Nigam's efforts...

We just have to be patient once more and see what comes of these efforts.

I dont know how much.. cant say.. ith such a protocol you are "half sleep" as you know.. But it was a lot and slowly injected. The patent dont learn us anything.. they just took a large range.

Actually I feel also very concern about the injection protocol, especially for the dp but we would need to

Any idea desmond ?

Tom...Aderans came up with a refined technique for injection of DP cells and got their "pen" system approved! I think you can even purchase it....let me do a bit of research...I'll get back to you

[tom vercetti]

Tom just of curiosity how many injections did you take? I was reading on this patent
http://www.google.com/patents/US20110305671 that in their protocol the made until 100 injection for cm2!! (i was so naive to think it would be at max 1 for cm2)

assuming 10 injections for cm2 and a scalp of 80cm2 we talk of 800 injections and more, to be onest the numbers is quite scared.

"In one aspect of the invention, the number of injections is 5 to 100 injections per square centimeter of the scalp, optionally 10 to 50 injections per square centimeter. In another aspect, 10 or 15 injections per square centimeter are performed. In another aspect of the invention, up to 50 or 60 injections per square centimeter are performed"

I dont know how much.. cant say.. ith such a protocol you are "half sleep" as you know.. But it was a lot and slowly injected. The patent dont learn us anything.. they just took a large range.

Actually I feel also very concern about the injection protocol, especially for the dp if there is a specialist in pharma here maybehe can give his mind about is it possible to make a vehicule and then reach a large area every injection.

Any idea desmond ?

@Arashi, yes for sure, I will post macro pics as you want no problem. But result is the same than before.

[Boldy]

so why they don't have never offered to their patients? Maybe the HT business is more profitable, we should remember before start complain about Nigam every time

Indeed mari0s, the thing is, why would you invest, and take ricks, if you have already a successful running clinic? regarding arvid, he has a very successful clinic line, nigams, has already 2 full clinics with 6-8 patients per day, however he still invests allot in improving the current techniques.

People don't seem to see this fact.

3d culture is to time consuming(the process would be approximately 8-10 weeks per patient), calculated per hour, its much smarter to make money with a HT... very sad that. the business are there just for money.. something we should not forget.



also, not to forget, in india you wont have the regulations issues, that you have in europe/us.

I have received my pics from nigams, and I think I will have time today to make my post, about my temporal hairline restoration, we used some different approach, than what he used to its a experiment that looks good so far.


Boldy

[Arashi]

So Tom, on HS, you stated that Dr Nigams was 'too busy' to make pictures. Can you maybe shoot some pictures yourself then of your recipient and post them ? Thanks !!

[mari0s]

Yeah Mario, if Histogen, Replicel or Aderans ever come out we will need over 1000 injections to cover the NW5 area!

I know some patients received those numbers in the Intercytex trials, which is scary to say the least...no pain no gain!

I'd do it though if it proves to be safe though...half an hour of suffering for a decade of happiness

Hi, nor Tom nor Wesley have spoken about this number so i was curios of how many have actually taken. :P
I wish it would be required only half an hour but i'm afraid at least two days. Replicel have develop a new kind of syringe but i don't know if could be really useful in this kind of matter.

http://rls.redrocketblastoff.com/product-pipeline/rci-02-injector/

About safety, here in Italy a huge mess happen when Stamina Foundation has been allowed to use mesenchymal cells from bone marrow, so far no one showed problems of any kind. Replicel and aderans use mesenchymal cells form DP which have proven to be safe so far (they have more than 10 years of trials on their back)

About the patent i've linked i have noticed that has been registered more than 2 yrs ago under Alvi Armani who is (was?) a HT surgeon and show a complete temporal restoration (in terms of quantity, i don't know about density) so why they don't have never offered to their patients? Maybe the HT business is more profitable, we should remember before start complain about Nigam every time

[veca]

Yeah Mario, if Histogen, Replicel or Aderans ever come out we will need over 1000 injections to cover the NW5 area!

I know some patients received those numbers in the Intercytex trials, which is scary to say the least...no pain no gain!

I'd do it though if it proves to be safe though...half an hour of suffering for a decade of happiness

Desmond84, what do you think about the safety of Dr. Nigams procedure?

[Desmond84]

Yeah Mario, if Histogen, Replicel or Aderans ever come out we will need over 1000 injections to cover the NW5 area!

I know some patients received those numbers in the Intercytex trials, which is scary to say the least...no pain no gain!

I'd do it though if it proves to be safe though...half an hour of suffering for a decade of happiness

[mari0s]

Tom just of curiosity how many injections did you take? I was reading on this patent
http://www.google.com/patents/US20110305671 that in their protocol the made until 100 injection for cm2!! (i was so naive to think it would be at max 1 for cm2)

assuming 10 injections for cm2 and a scalp of 80cm2 we talk of 800 injections and more, to be onest the numbers is quite scared.

"In one aspect of the invention, the number of injections is 5 to 100 injections per square centimeter of the scalp, optionally 10 to 50 injections per square centimeter. In another aspect, 10 or 15 injections per square centimeter are performed. In another aspect of the invention, up to 50 or 60 injections per square centimeter are performed"

[tom vercetti]

I wasn't suggesting he treat patients for free. He could charge for procedures, but still ask for a deposit that will be returned when patient comes back to have pictures taken of the results or supplies the doctor
those pictures. This isn't some bizarre new practice. Other HT doctors do this.

I have a tough time believing that Nigam's patients are all so blissed out over their results and newfound self-confidence that they can't be bothered to return for pictures or update the community on their progress.

I know what you was suggesting.. But I replied you that dr nigam thought make a system of deposit wasnt necessary.. I would have done the same anyway. just few people are just asshole.

[Thinning@30]

Originally Posted by Thinning@30 View Post
If Dr. Nigam is confident in his treatment, why doesn't he just ask patients to pay a deposit that will be released when they provide him with updated results?

because NSN was a "senior member" of forum, and trusty person, until he get his free treatment.

I wasn't suggesting he treat patients for free. He could charge for procedures, but still ask for a deposit that will be returned when patient comes back to have pictures taken of the results or supplies the doctor
those pictures. This isn't some bizarre new practice. Other HT doctors do this.

I have a tough time believing that Nigam's patients are all so blissed out over their results and newfound self-confidence that they can't be bothered to return for pictures or update the community on their progress.

[tom vercetti]

Just to give some news from dr nigam:

He is developing a new technique of hair doubling and has even tested on boldy his first version. In the coming months, we will see impressive result in terms of doubling. The difference will be that he will be able to have graft of 3 and 4 hairs.. as in fue.. If you remember this was the only problem of the hair doubling and dr gho pocedure.. Now dr nigam can go ahead of that. And this time I advised him to not disclose anuthing on the forum as many HT Professional are around.

Really guy sky is more and more clear

[tom vercetti]

If Dr. Nigam is confident in his treatment, why doesn't he just ask patients to pay a deposit that will be released when they provide him with updated results?

because NSN was a "senior member" of forum, and trusty person, until he get his free treatment.

[Thinning@30]

If Dr. Nigam is confident in his treatment, why doesn't he just ask patients to pay a deposit that will be released when they provide him with updated results?

[tom vercetti]

Wait are you saying NSN came back to DR nigam asking for further treatment? IF thats the case and I was Dr Nigam I'd tell him to post his results or get lost haha

Yes I'm serious as im often in contact with dr nigam.. I really asked him to not accept.. I know it's crazy but this NSN is really a shame. He didnt give his feedback / pictures he should have been, just disappear, but 5 months later he got result more and more and just want continue as he wanted to do initially (if you remember at the beginning he planned to do that until he get full head of hair). As I said I cant accept injustice, and in that case it is.