Link to Topical Finasteride

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  • yan
    Senior Member
    • May 2013
    • 156

    #46
    Originally posted by Conpecia
    Is there any news on this? After the Histogen letdown this is absolutely number 1 on my list of treatments that might actually exist in the near future. All of us who are looking to maintain and cannot take oral fin due to sides need to research this and see what the deal is with the chitosan film, what the timeline is on an official release, whether we can get it made at a lab, make it ourselves, economics, etc. This and RU are pretty much all we have atm and I'd rather go with the more proven treatment.

    We should contact Kane about this. As well as Mpbtreatments.
    But you understand that topical fin will reduce serum dht by nearly the same amount as oral fin? Its useless if you cant tolerate fin oral...
    Topical fin is just for those who want to reduce scalp dht even further than with fin oral.

    Comment

    • Pentarou
      Senior Member
      • Apr 2013
      • 482

      #47
      Thought: could topical fin be better for preserving hairlines than oral fin?

      Could topical fin keep working for longer than the 5 or so years that oral fin gives you?

      Comment

      • thechamp
        Senior Member
        • Jan 2011
        • 1763

        #48
        Cob

        Originally posted by Cob984
        This, One day im like lets just continue with Kar, the 2nd day RU, the third topical Fin, the 4th some Spectral product. FML,
        the worst part is inspite of all the combinations there is nothing that really helps my hair w/o sides, feel like im cursed
        Cob try promox I'm going to give it a go you can order combinations I'm going to order topical fin without azelic acid doesn't agree with me

        Comment

        • thechamp
          Senior Member
          • Jan 2011
          • 1763

          #49

          Comment

          • goldbondmafia
            Senior Member
            • Oct 2011
            • 406

            #50
            has anyone on here actually been using topical fin for a while and seen results?

            Comment

            • Conpecia
              Senior Member
              • Sep 2011
              • 904

              #51
              Originally posted by yan
              But you understand that topical fin will reduce serum dht by nearly the same amount as oral fin? Its useless if you cant tolerate fin oral...
              Topical fin is just for those who want to reduce scalp dht even further than with fin oral.
              No this is a new patent on a new vehicle that inhibits systemic absorption. This is not topical fin like crushed up propecia in a pg vehicle or whatever.

              Comment

              • yan
                Senior Member
                • May 2013
                • 156

                #52
                Originally posted by Conpecia
                No this is a new patent on a new vehicle that inhibits systemic absorption. This is not topical fin like crushed up propecia in a pg vehicle or whatever.
                Serum DHT was reduced by
                69.3–74.0% with P-3074 b.i.d., 67.6–80.4% with P-3074 o.d., and
                69.7–76.1% with the oral formulation.

                Comment

                • Desmond84
                  Senior Member
                  • Oct 2012
                  • 987

                  #53
                  Hey guys...I did a few calculations and realised that each 100ml bottle will contain 250mg of finasteride. That's 50 x 5mg finasteride tablet or 250 x 1mg finasteride tablets you'll be using in 1 month!

                  Now if you use 2ml per day that means you applied 5mg of finasteride on your skin. On average 10% gets absorbed which means 0.5 mg enters your bloodstream!

                  I really doubt this would reduce the risks of sides and wanted to warn those that are particularly sensitive to finasteride!

                  This kind of explains why plasma dht was reduced by the same amount compared to oral tablets...

                  Hope it helps...

                  Comment

                  • rdawg
                    Senior Member
                    • Jun 2012
                    • 996

                    #54
                    Originally posted by Desmond84
                    Hey guys...I did a few calculations and realised that each 100ml bottle will contain 250mg of finasteride. That's 50 x 5mg finasteride tablet or 250 x 1mg finasteride tablets you'll be using in 1 month!

                    Now if you use 2ml per day that means you applied 5mg of finasteride on your skin. On average 10% gets absorbed which means 0.5 mg enters your bloodstream!

                    I really doubt this would reduce the risks of sides and wanted to warn those that are particularly sensitive to finasteride!

                    This kind of explains why plasma dht was reduced by the same amount compared to oral tablets...

                    Hope it helps...
                    An interesting question was raised earlier and i'm not sure if it was answered.

                    Because this is localised to the hair, would it be better at causing maintenance/growth to the hair??

                    Comment

                    • Conpecia
                      Senior Member
                      • Sep 2011
                      • 904

                      #55
                      Originally posted by Desmond84
                      Hey guys...I did a few calculations and realised that each 100ml bottle will contain 250mg of finasteride. That's 50 x 5mg finasteride tablet or 250 x 1mg finasteride tablets you'll be using in 1 month!

                      Now if you use 2ml per day that means you applied 5mg of finasteride on your skin. On average 10% gets absorbed which means 0.5 mg enters your bloodstream!

                      I really doubt this would reduce the risks of sides and wanted to warn those that are particularly sensitive to finasteride!

                      This kind of explains why plasma dht was reduced by the same amount compared to oral tablets...

                      Hope it helps...

                      Guys, this makes no sense! Why are they developing a topical product if it doesn't reduce side effects?! Do they think it will work even better than oral finasteride? So confused!!

                      Comment

                      • Jcm800
                        Senior Member
                        • Jan 2011
                        • 2614

                        #56
                        Originally posted by oscar32
                        I've had a lot of success with topical finasteride by crushing up the tablets from this site Saferonlinepharmacy.com and making a solution
                        out of my shampoo. You don't need a doctors script to get it from them but it works great.
                        Sure it does Mr low post count who mentions sellers..

                        Comment

                        • Kiwi
                          Senior Member
                          • Mar 2011
                          • 1087

                          #57
                          Originally posted by Jcm800
                          Sure it does Mr low post count who mentions sellers..
                          LOL - exactly what I was thinking...

                          Comment

                          • kmit028
                            Member
                            • Feb 2013
                            • 30

                            #58
                            Fin is a type II 5α-reductase inhibitor!

                            Fin is a type II 5α-reductase inhibitor. 5α-reductase is an enzyme that converts testosterone to dihydrotestosterone (DHT).

                            So FIN does not react with or affect DHT directly. It only inhibits the chemical (5α-reductase) that creates DHT from Testosterone.

                            So if you have FIN in your scalp but not in your blood, wouldnt it be useless as the enzyme 5α-reductase will still make DHT???

                            Could someone confirm this as not sure my science is quite right

                            Comment

                            • thechamp
                              Senior Member
                              • Jan 2011
                              • 1763

                              #59
                              Originally posted by oscar32
                              I've had a lot of success with topical finasteride by crushing up the tablets from this site Saferonlinepharmacy.com and making a solution
                              out of my shampoo. You don't need a doctors script to get it from them but it works great.
                              How many tablets did you crush in your shampoo ? Maybe I can avoid systematic absorbstion like this!!

                              Comment

                              • doke
                                Senior Member
                                • Jun 2009
                                • 1464

                                #60
                                Topical spironolactone works at the site and not in the blood as it is good for skin acne and i think that dutas and finast will be systemic and that was the same for topical flutamide which caused side effects.
                                Thats why people try ru58841 as it was supposed to be non systemic and work at the site of application although there have been some success with topical progestorone and cyclosporin topical combined with minoxidil but i think some clinics using this also use oral finasteride as well and you may have to have regular blood tests to check hormon levels.
                                I have been using hairagain which has some natural progestorone in it as well as regrowth agents and i must say the gel is very nice to use its available in uk and us as im using with the igrow laser helmet.

                                Comment

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