TAKEAWAY FROM WCHR 2013 Edinburgh, UK @ Dr. NIGAM

[534623]

Hahahaha those pictures are hilarious. All the people Nigam is taking pictures with have that WTF look on their faces. Like "who the **** is this guy and why am I taking a picture with him?"

Are you sure?


Oh well, they will regret these (marketing-)snapshots [to impress kids] soon ...

By the way - is Dr. Cotsarelis losing his hair or is it just the lightning?
Anyway, it doesn't matter. The guy who will cure him is next to him...lol

[Kiwi]

Hahahaha those pictures are hilarious. All the people Nigam is taking pictures with have that WTF look on their faces. Like "who the **** is this guy and why am I taking a picture with him?"

Most conference photos are like that.

Good job Nigram. I hope you blow Dr Gho's technique to smithereens - if your technique becomes the gold standard you'll be our hero!!!

You can always move to a country like New Zealand that doesn't recognise archaic American patent laws ;P

Oh wait. You already do!!! Hazah!!!!

[534623]

Most conference photos are like that.

No - that is not true ...

[Arashi]

Hahahaha those pictures are hilarious. All the people Nigam is taking pictures with have that WTF look on their faces. Like "who the **** is this guy and why am I taking a picture with him?"

LOL. But then again, it IS nice that he actually went there and fed back some things to this forum.

[Conpecia]

[QUOTE=drnigams;121938]http://www.google.com/patents/EP2153836A1?cl=en
The above link to patent for topical finasteride should help.
You can contact the company directly.
If we have any pharmacist ,skin permeation expert as forum member..they can be of help.
I will work on it..give me some time .

Topical finasteride looks good, 71% scalp DHT reduction with low systemic absorbtion, any ideas when this will be available Dr Nigam and where we can get our hands on it?

I think the dermal sheat cells is a good shout from Jahoda, do you think you could apply the 3D spheroidal DP culture with Dermal SHEAThttp

Looks like we could see a topical blend of minox and fin with this new "film" as a vehicle. That'd make things so easy just apply it and move on. Man this can't come soon enough.

[rdawg]

Would topical fin have to go through the same regulations being as finasteride is already proven safe?

wouldnt it just need a 1 year phase III kind of trial?

someone tell me how this would work, would love to get topical fin, not that i'm having issues with regular fin.

Wouldn't it work better too since it would be more localised/direct to the scalp?

[FearTheLoss]

Would topical fin have to go through the same regulations being as finasteride is already proven safe?

wouldnt it just need a 1 year phase III kind of trial?

someone tell me how this would work, would love to get topical fin, not that i'm having issues with regular fin.

Wouldn't it work better too since it would be more localised/direct to the scalp?

Hasson and Wong already get it for their patients....not sure what we can do in the USA

[DepressedByHairLoss]

No - that is not true ...

Haha, that cracked me up. People like her have been tinkering with mice for decades but have not done a damn thing to benefit humans.

[DepressedByHairLoss]

I really do salute Dr. Nigam very much though. He is really trying to give us less-invasive and just better options to regrow hair, and not just simply offering the same old tired FUT surgery.

[drnigams]

rdawg,
Doctors can prescribe off label use of topical finasteride since it is approved by FDA for oral use..
Like doctors prescribe lattise(a product of allergan) off label as it has been approved by FDA,USA for growing eyelashes.
Silicion fillers have been cleared by FDA for opthalmic use,and doctors in USA are using it for permanent fillers for face through microdroplet technique.
In INDIA,doctors can compound and dispense a new formulation,provided every ingredient has an FDA approval and bought from FDA registered supplier.But cannot keep this formulation in the pharmacy for general public unless cleared by FDA for it's claims.
That means ,i can compound and dispense to my patients from my clinic or by courier once i find the right solution and vehicle of topical finasteride.
Although this has to be for use of individual patient and not for sale in the market..
If a company launches this product as a drug than minimum it has to do,is prove it's efficacy with trials before FDA allows it's claim...

Would topical fin have to go through the same regulations being as finasteride is already proven safe?

wouldnt it just need a 1 year phase III kind of trial?

someone tell me how this would work, would love to get topical fin, not that i'm having issues with regular fin.

Wouldn't it work better too since it would be more localised/direct to the scalp?

[MrBlonde]

rdawg,
Doctors can prescribe off label use of topical finasteride since it is approved by FDA for oral use..
Like doctors prescribe lattise(a product of allergan) off label as it has been approved by FDA,USA for growing eyelashes.
Silicion fillers have been cleared by FDA for opthalmic use,and doctors in USA are using it for permanent fillers for face through microdroplet technique.
In INDIA,doctors can compound and dispense a new formulation,provided every ingredient has an FDA approval and bought from FDA registered supplier.But cannot keep this formulation in the pharmacy for general public unless cleared by FDA for it's claims.
That means ,i can compound and dispense to my patients from my clinic or by courier once i find the right solution and vehicle of topical finasteride.
Although this has to be for use of individual patient and not for sale in the market..
If a company launches this product as a drug than minimum it has to do,is prove it's efficacy with trials before FDA allows it's claim...

So you will do your own testing to find the right solution? We are talking months of testing and patient results then before you send out your own topical Fin?

How quickly do you think you can have batches ready to send?

[Arashi]

rdawg,
If a company launches this product as a drug than minimum it has to do,is prove it's efficacy with trials before FDA allows it's claim...

Yup. Minimum is a phase III trial to prove efficacy. So probably a 2 year timeframe before we'll see it on the market.

[drnigams]

Blonde, my major focus of work at present is donor doubling and injections of growth factors,stemcells,and dp cultured cells..whatever time will be left ..i will work on thsi..but any guy into phd on skin permeation will be a better bet to prepare than me..i will also be discussing with experts in skin permeation,the swiss company and also annika voidt from germany ,who's research work is into targetted drug delivery... to prepare the formulation.

So you will do your own testing to find the right solution? We are talking months of testing and patient results then before you send out your own topical Fin?

How quickly do you think you can have batches ready to send?

[drnigams]

Arashi,did you have a look at three studies i posted at hs proving our hypothesis of donor doubling...wherein lower follicle if amputated can regenerate it's own dermal papilla...infact there was a paper on unlimited follicle hair transplant at WCHR...these findings confirm til HM comes doubling is the best solution...

Yup. Minimum is a phase III trial to prove efficacy. So probably a 2 year timeframe before we'll see it on the market.

[rdawg]

Yup. Minimum is a phase III trial to prove efficacy. So probably a 2 year timeframe before we'll see it on the market.

essentially for on label yes, but off label we can get this stuff much sooner than that.

that's still not that far, but i'm not sure I got an answer to my other question, would the efficacy be better(at least in theory) than regular oral fin since it's more localised to the hair? or would it essentially have the same effect?