TAKEAWAY FROM WCHR 2013 Edinburgh, UK @ Dr. NIGAM

[drnigams]

Made New...... Star Research Friend's

Dr. Nigam with Dr. Gerd Lindner & Ken Washniek, CEO, Aderans, at WCHR2013, Edinburgh, UK


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Dr. Nigam with Mike Philpott, at WCHR2013, Edinburgh, UK


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Dr. Nigam with Dr. George Cotsarelis, at WCHR2013, Edinburgh, UK


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Dr. Nigam with Valerie Randall, Chair person of Scientific Committee, & Dr. Costarelis, at WCHR2013, Edinburgh, UK


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Dr. Nigam with Annika Vogte, at WCHR2013, Edinburgh, UK


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She is focusing on nano and virus like particles to deliver specific molecules to targeted areas in hair follicle in vivo and specifically treating hair stem cells by targeted nano molecular therapies.

Dr. Nigam with Elaine Fuchs & Valeria Randall, at WCHR 2013, Edinburgh, UK


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Dr. Nigam with Rajesh Thangapazham at WCHR2013, Edinburgh, UK


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He is a very promising young researcher and he may become consultant to our Lab shortly. He has presented his paper at WCHR20103 tittled "Enhancing hair follicle neogenesis in bioengineered human skin substitute". His company has a collaboration with Dr. Cotsarelis. He is from Pennsylvania, USA

Dr. Nigam with Colin Jahoda, at WCHR2013, Edinburgh, UK


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Dr. Nigam with Kurt Stenn, MD Vice President and Chief Scientific Officer, Aderans Research, at WCHR2013, Edinburgh, UK


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[UK_]

What a legend!!!

[clandestine]

Well, I'm impressed.

[bald fighter]

w0000000w what a superstar


now go back to your work with photoshopping

[drnigams]

And they were very kind and open to share and support , as i mail them my findings with new miniclincal experiments on 3D spheroidal DP culture,growth factors etc.
Jahoda corrected me by asking me to use dermal sheath cells rather dermal papilla cells alone with my HM and doubling.
I invited washniek to India,we will meet again at Sanfrancisco,USA at ISHRS,2013 ,may be i will be ready with my presentation by then.
Dr Gerd should be consultant to my lab, by next month.
Found a yound innovative researcher from pennsylvania Dr Rajesh(who presented his paper titled..Enhancing hair follicle neogenesis in bioengineered human askin substitutes) who's company has a collabration with cotsarelis.

Hellouser,i conveyed to most of them ,till how long it will be only research..it is high time we reach somewhere near cure.
Some other TAKE AWAYS...
1)How to work on topical finasteride with special carriers to have consistent high local scalp concentrationand targetted delivery ,thus avoiding oral finasteride and it's side effects in the near future.
2)Follicle testing research moving towards in vitro lab with follicle kept alive for atleast 15days,thus allowing the researchers to see effects of vrious molecules on the follicle growth,as against just (alien) mouse studies..As ralf paus from uk said mouse originated from asia and humans from africa..
Also more research experiments now carried with human skin created in lab,grafted into SICD mouse and implantation of pluripotent mouse keratinocytes and human cultured dp cells ..with successfull follicle regen in 6 weeks.
3)Donor doubling ,now confirmed by independent study by LIN,HUANG of Shantou university ,china...confirming that a bisected follicle with outer root sheath can grow it's own dermal papilla back in vitro in lab (with specail culture medium) and mouse..These guys have developed a special instrument to cut the follicle in vivo with a scissor like structure as punch.
I was fortunate to see major part of congress being focussed on DP culture models ..3d spheroidal,culture mediums with supplements..layered models,hanging drop models,capsules,scaffolds etc. This would help our lab move forward with respect to trichogenic dp culture.

Will share many other take aways soon..

What a legend!!!

[UK_]

Topical finasteride looks good, 71% scalp DHT reduction with low systemic absorbtion, any ideas when this will be available Dr Nigam and where we can get our hands on it?

I think the dermal sheath cells is a good shout from Jahoda, do you think you could apply the 3D spheroidal DP culture with Dermal SHEATH cells?

[Henkeh91]

Thanks Dr! I have the same question as UK_ regarding topical finas.

[Arashi]

Thanks Dr! I have the same question as UK_ regarding topical finas.

It depends on what they negotiate with the FDA. A single Phase III study mainly to show efficacy could be enough. If I remember correctly from the abstracts it were researchers in Asia who did the test, maybe that can be used in the negotiations with FDA.

Either way, this should be available within 2 years, maybe sooner.
See: http://www.targethealth.com/PDF/Post...OralDrugsv.pdf

[Arashi]

Probably the more interesting question would be: is it easy to make this yourself ?

[Artista]

Dr Nigam, we are all so very appreciative of your efforts to educate us here on BTT. You have proven yourself to be a person of interest and I look forward to more of your experiences at the Conference ..Im very GLAD to hear that you will be at the San Fransisco Conference in October!!
Dr , I would like to have a private conversation with you regarding the October Conference at your earliest convenience. Thank you.

[hairy]

Dr. Nigam you are the Amitabh Bachchan of the hair loss world!

Thanks for all your efforts posting here, and collaborating with all these researchers. Seems like the researchers and scientists have less ego then HT surgeons on average.

[Conpecia]

Dr. Nigam: Thanks for your efforts!! Your work ethic is nothing short of phenomenal, and I commend you for your diligence and attempts to keep us informed.

Very excited about topical fin; if we can minimize systemic sides (particularly feminization) and maintain most of the efficacy of oral fin, I'll be back in business!! Do you happen to know a timeframe for topical fin?

Also: killer shades!

[UK_]

I think it's true that a lot of the HT surgeons are not interested in better treatments because it may impact their profession, I also think this is sickening and disgraceful behaviour, it's not just people with MPB that will benefit but burn victims and individuals with other forms of alopecia including people undergoing chemotherapy!

[DepressedByHairLoss]

I think it's true that a lot of the HT surgeons are not interested in better treatments because it may impact their profession, I also think this is sickening and disgraceful behaviour, it's not just people with MPB that will benefit but burn victims and individuals with other forms of alopecia including people undergoing chemotherapy!

Bro, I've been echoing these sentiments for the longest time and this statement is so obviously true to me. It's all driven by money.

Also, on another topic, I do not even believe that topical finasteride would need FDA approval at all since it is already approved as a hair loss treatment. It's kind of similar to how Spencer had a pharmacy make him a topical minoxidil concoction before it was approved by the FDA for hair loss (since minoxidil was already FDA-approved for another condition).

[UK_]

Yep, I really hope Dr Nigam can give us some information on where we can obtain the topical fin they've developed - I understand Dr Nigam was given some samples to test too!