Complete RU58841 Usage Guide

[Paul73]

Cancer most funny thing i have heard.. Anti androgens are used for anti-cancer generally, makes much sense!

Start here;

http://en.wikipedia.org/wiki/Discovery_and_development_of_antiandrogens

If you can't research general information and draw logical conclusions from it and put effort into it, don't even start on any experimental is my advice really.
You don't even know that it was tested in humans even till phase 2.

I confess that I expected a more polite and convincing answer. Instead, you chose to be ironic. And you know why? Because nobody knows the answer to the risk of cancer involving UK.

The answer will always be without foundation and logic. Precisely because there is insufficient data to eliminate what you think is very funny.

I'm not the first to mention the possibility of cancer with the use of RU. If you are as well informed as suggest, you should know that there are tons of articles and threads talking about cancer risk on RU. So i am not the first to make this claim. If you really have not read about this before, i suspect that you are the one who needs to do a better research.

I researched a lot in different sources. Read all threads at this and other websites regarding RU. I even talked to doctors personally. And they agree that cancer is a possibility in the long run since we do not have complete human tests done.

As pointed out by Duke in his post

I would really like to start with RU right away but I also have problems using a chemical that was not tested on humans at all!

Especially that it increases cellular replication rate worries me a bit since this is what I would imagine causes cancer (uncontrolled cellular growth)


Desmond commented about it in a recent post too:

It is important to know the difference between CB & RU . Although They are both anti - androgens , RU is an active ingredient with 20-30 % systemic absorption after topical application .

CB on the other , is only active When applied to the skin . By the Time It Reaches into the lower skin layers and enters the bloodstream , specific enzymes have broken it down to que inactive chemicals are rapidly excreted from the body .

That is why so many ppl still report adverse sexual effects after using RU . So in my opinion either take micro - doses of Finasteride orally ( 0.25mg/twice per week ) or crush it up and dissolve it in the vehicle and apply it topically . At least you know the safety record of finasteride and possible long term effects . The member said earlier with the RU you are playing russian roulette or the RU Roulette LOL .


Still think it's funny? I find disturbing and i was just trying to alert you and other guys about it. I was planning to use RU and after many weeks researching i still didn't find the answer to this question:

Could RU cause cancer in the long run?

Since we don't have the answer (and will never know because the project was abandoned), the YES to this question is also a possibility.

I hope I'm not being rude in my answer. I admire your posts and all the excellent information you bring to this forum. But again, I expected a better response from you.

[Swooping]

First of all you do know how cancer works a bit don't you? If not first watch this video, it is explained easy; https://www.youtube.com/watch?v=Qja4z1HGDQo&feature=kp

Btw, sorry I did not mean to offend you. There are many people who use bro- science on the forums. Let's take these 2;

"I would really like to start with RU right away but I also have problems using a chemical that was not tested on humans at all!

Especially that it increases cellular replication rate worries me a bit since this is what I would imagine causes cancer (uncontrolled cellular growth)"

First of all it was tested in humans. Secondly you do know it is completely damn obvious that the cellular replication rate is going to increase (profileration of the cells) when we block the AR. We who have AGA actually lack the profileration rate in our cells (miniaturized hair) against non-aga control. Here just a movie posted about it of the hair congress, you'll understand;

https://www.youtube.com/watch?v=IEbLm_cgJKI

Although you will find tons more if you search for it. Even finasteride will increase your profileration rate because androgens (DHT) will have less chance to increase paracrine signalling alteration etc through the AR. Same with minoxidil, although through other mechanisms. For instance minoxidil, actually DECREASES P53. We know that androgens induce ROS damage through the AR and P53 gets activated and is overexpressed bald scalp. Go look up on P53 i bet you'll be insanely scared to use minoxidil now lol. We actually want to have more profileration rate in our cells, if you don't want that you better stay bald. I can link you to studies about it if you want.

If you don't want cancer I suppose you better stop drinking, don't go outside without completely covered in UV protection, don't ever smoke, dont use fin, minox etc. But even then you ain't safe because most of it is genetically predisposed anyway. I always amaze myself, some people who live completely healthy and die at a young age of cancer and some people who smoke like a chain monster, drink every day and do drugs still do not develop cancer when they are 80+ years old. Don't you?

Again RU action is of a anti-androgen go look up on other anti-androgens. They are used AGAINST cancer. That would be ironic if molecules for anti-androgens would induce cancer, wouldn't it?

About Desmond this 20-30% systemical approach of RU, i have never read this. Show me the proof for this. I have read every study of RU pretty thoroughly and never have read this 20-30% systematical thing. But prove me wrong if this is true, ill def lower my RU dosage lol. Sorry for spelling mistakes btw wrote this pretty fast.

[g0910]

Two questions please.

Have any of you long time RU users experienced any other symptoms such as muscle loss or androgen/body hair thinning (beard, armpits, chest/stomach, pubic, arms & legs)? I really would like to know how systemic this topical is.

I know that long-term Propecia use causes body hair loss because I'm a prime example. I've been on Propecia for over 10 years and lost almost all of my body hair where I used to be as hairy as a bear before hand... chest hair - stomach hair... all gone. My head hair has held up fairly well though.

Also, I have had a hard time gaining muscle where before starting propecia, I was able to gain muscle mass so easily. Some of the reason may be age, but I think it's mostly due to the lack of DHT. (My Total T and Free T are good )

For these reasons, in the last couple of years I've been starting to wean my Propecia dose(1mg) from every day to 3x/week to 2x/week and now to 3/4 mg 2x/week. Does anyone think that using RU, will pickup the slack at all? I'm 50 and I'm at a NW3V/4.

I've never tried Minox or any other special shampoos or topicals. Would like to try RU only if it's not too systemic. Any advice is welcome. Thanks.

[lilpauly]

Have any of you long time RU users experienced any other symptoms such as muscle loss or androgen/body hair thinning (beard, armpits, chest/stomach, pubic, arms & legs)? I really would like to know how systemic this topical is.

I know that long-term Propecia use causes body hair loss because I'm a prime example. I've been on Propecia for over 10 years and lost almost all of my body hair where I used to be as hairy as a bear before hand... chest hair - stomach hair... all gone. My head hair has held up fairly well though.

Also, I have had a hard time gaining muscle where before starting propecia, I was able to gain muscle mass so easily. Some of the reason may be age, but I think it's mostly due to the lack of DHT. (My Total T and Free T are good )

For these reasons, in the last couple of years I've been starting to wean my Propecia dose(1mg) from every day to 3x/week to 2x/week and now to 3/4 mg 2x/week. Does anyone think that using RU, will pickup the slack at all? I'm 50 and I'm at a NW3V/4.

I've never tried Minox or any other special shampoos or topicals. Would like to try RU only if it's not too systemic. Any advice is welcome. Thanks.

I think u should try Minox first!

[g0910]

I think u should try Minox first!

Thanks. I guess it's not a bad idea. It's definitely a lot cheaper than RU. AND, I can always add RU later.

I've really been out of the loop and didn't realize until a few weeks ago that there where so many topical anti-androgen products and special shampoos. That's good news.

Is taking .75 mg of propecia twice a week unheard of? Thx.

[g0910]

I think u should try Minox first!

lilpauly, do recommend I try Minox in combo any other topical to speed results? Saba? But I still plan on introducing RU later if results from Minox are not sufficient. Thx.


Oh, One more thing. Should I expect initial shedding from Minox if I've been on Propecia?

[hellouser]

Oh, One more thing. Should I expect initial shedding from Minox if I've been on Propecia?

Yup.

[michaelmyersnyc]

Yup.

question.
say you bought: RU solution 50ML, 8% strength, with select carrier KB solution. how much of this stuff would you use a day for effectiveness?
would a vet please get back to me, thanks.

[lilpauly]

question.
say you bought: RU solution 50ML, 8% strength, with select carrier KB solution. how much of this stuff would you use a day for effectiveness?
would a vet please get back to me, thanks.

Buy the powder it's much cheaper

[lilpauly]

It will also buy much longer and u can adjust the dose , I recommend not to go over 5%

[lilpauly]

It will also last much longer and u can adjust the dose , I recommend not to go over 5%

[michaelmyersnyc]

Buy the powder it's much cheaper

lol i know that now but the deed is already done lol...im just looking for the answer to the question if u can help?

[lilpauly]

lol i know that now but the deed is already done lol...im just looking for the answer to the question if u can help?

It all depends really , most people they apply 1ml of ru , sometimes it's a little more , a little less if u target areas . If u bough kb apply it last ,

[Paul73]

First of all you do know how cancer works a bit don't you? If not first watch this video, it is explained easy; https://www.youtube.com/watch?v=Qja4z1HGDQo&feature=kp

Btw, sorry I did not mean to offend you. There are many people who use bro- science on the forums. Let's take these 2;

"I would really like to start with RU right away but I also have problems using a chemical that was not tested on humans at all!

Especially that it increases cellular replication rate worries me a bit since this is what I would imagine causes cancer (uncontrolled cellular growth)"

First of all it was tested in humans. Secondly you do know it is completely damn obvious that the cellular replication rate is going to increase (profileration of the cells) when we block the AR. We who have AGA actually lack the profileration rate in our cells (miniaturized hair) against non-aga control. Here just a movie posted about it of the hair congress, you'll understand;

https://www.youtube.com/watch?v=IEbLm_cgJKI

Although you will find tons more if you search for it. Even finasteride will increase your profileration rate because androgens (DHT) will have less chance to increase paracrine signalling alteration etc through the AR. Same with minoxidil, although through other mechanisms. For instance minoxidil, actually DECREASES P53. We know that androgens induce ROS damage through the AR and P53 gets activated and is overexpressed bald scalp. Go look up on P53 i bet you'll be insanely scared to use minoxidil now lol. We actually want to have more profileration rate in our cells, if you don't want that you better stay bald. I can link you to studies about it if you want.

If you don't want cancer I suppose you better stop drinking, don't go outside without completely covered in UV protection, don't ever smoke, dont use fin, minox etc. But even then you ain't safe because most of it is genetically predisposed anyway. I always amaze myself, some people who live completely healthy and die at a young age of cancer and some people who smoke like a chain monster, drink every day and do drugs still do not develop cancer when they are 80+ years old. Don't you?

Again RU action is of a anti-androgen go look up on other anti-androgens. They are used AGAINST cancer. That would be ironic if molecules for anti-androgens would induce cancer, wouldn't it?

About Desmond this 20-30% systemical approach of RU, i have never read this. Show me the proof for this. I have read every study of RU pretty thoroughly and never have read this 20-30% systematical thing. But prove me wrong if this is true, ill def lower my RU dosage lol. Sorry for spelling mistakes btw wrote this pretty fast.

Thank you for answering with so many details. I understand your view on it. But the truth is that we will only be 100% sure about RU safety regarding cancer if any company restarts the trials and conclude them.

Like Pate commented on another thread, it is still an unaproved substance. This fact makes cancer a possibility.

[hellouser]

Thank you for answering with so many details. I understand your view on it. But the truth is that we will only be 100% sure about RU safety regarding cancer if any company restarts the trials and conclude them.

Like Pate commented on another thread, it is still an unaproved substance. This fact makes cancer a possibility.

I think the LARGE number of people having used RU58841 over the years should be taken into account.