S-equol again

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  • cthulhu2
    Member
    • Jun 2014
    • 71

    Originally posted by thechamp
    So who's going to try topical s eqoul can we just Pop a few in minoxdill ?
    depends on the molecular weight(Dalton). Typically, chemicals need to have a molecular weight of 500 Daltons or less to penetrate the skin.

    Comment

    • PinotQ
      Senior Member
      • May 2010
      • 188

      Originally posted by cthulhu2
      depends on the molecular weight(Dalton). Typically, chemicals need to have a molecular weight of 500 Daltons or less to penetrate the skin.
      The molecular weight of s-equol is 242.27 g/mol. Not sure exactly how the conversion works but I believe equol is well under 500 Daltons and is classified as a small molecule. This link suggests 1 Dalton is equol to 1 g/mol: https://thetfp.com/tfp/tilted-knowle...ons-g-mol.html

      Comment

      • NeedHairASAP
        Senior Member
        • Jul 2011
        • 1410

        get some of desmond's vesapro creme and try it. Its like 20 bucks for a tube.

        Comment

        • thechamp
          Senior Member
          • Jan 2011
          • 1770

          Does any one think s eqoul will be effective as a topical and how would I make it in to a topical ?

          Comment

          • ItchForTheCure
            Junior Member
            • Sep 2014
            • 7

            Hey guys,

            So it has been about 2 months since I started taking 54mg equol per day. Here are some updates:

            I am still shedding like the family dog.
            The wrinkles on my forehead are nearly gone and my skin looks a lot smoother
            More importantly, I am seeing new hairs growing out on the front. Some of the hairs are vellus, but many of them appear to be terminal black hair coming out. The new hairs starting coming out about 1-2 weeks ago.

            As for any sides I haven't experienced any. My body weight is unchanged and everything in the pants is functioning normally.

            I'll update you guys again at the 3 month mark.

            Comment

            • thechamp
              Senior Member
              • Jan 2011
              • 1770

              Originally posted by ItchForTheCure
              Hey guys,

              So it has been about 2 months since I started taking 54mg equol per day. Here are some updates:

              I am still shedding like the family dog.
              The wrinkles on my forehead are nearly gone and my skin looks a lot smoother
              More importantly, I am seeing new hairs growing out on the front. Some of the hairs are vellus, but many of them appear to be terminal black hair coming out. The new hairs starting coming out about 1-2 weeks ago.

              As for any sides I haven't experienced any. My body weight is unchanged and everything in the pants is functioning normally.

              I'll update you guys again at the 3 month mark.
              Did you gain weight with propecia ? Because i did ?

              Comment

              • kaz007
                Junior Member
                • Oct 2014
                • 2

                I guess the next step is for Adaaku and Itch to take a free DHT test. Adaaku, why don't you create a PayPal account and post the email address here? Each person giving $10 to $20 each should quickly get the test funded. Guys, skip that $6 Starbucks coffee a couple of times for science and your hair!

                Comment

                • kaz007
                  Junior Member
                  • Oct 2014
                  • 2

                  Originally posted by thechamp
                  Did you gain weight with propecia ? Because i did ?
                  From http://techtransfer.byu.edu/products...weight-control

                  "Equol is also involved in weight control, preventing obesity and stimulating fat (adipose) tissue loss."

                  Comment

                  • ItchForTheCure
                    Junior Member
                    • Sep 2014
                    • 7

                    Originally posted by thechamp
                    Did you gain weight with propecia ? Because i did ?
                    I didn't gain weight on propecia. I only took propecia once and experienced all the cognitive side effects and muscle weakness over night. I couldn't lift up my smart phone in the morning with one hand. I also lost the function what's in my pants for about 1.5 months. There might have been an "adjustment" period, but getting those sides made me drop it after one pill. I am totally fortunate I was able to make a full recovery. Guys those pills are no joke.

                    If equol was going to give me sides, I should have gotten them by now. I think this alone proves that equol works differently than propecia, aka doesn't mess with your neurosteriods. Whether it is working, I'll let time decide that.

                    Comment

                    • bananana
                      Inactive
                      • Feb 2012
                      • 525

                      Originally posted by ItchForTheCure
                      Hey guys,

                      So it has been about 2 months since I started taking 54mg equol per day. Here are some updates:

                      I am still shedding like the family dog.
                      The wrinkles on my forehead are nearly gone and my skin looks a lot smoother
                      More importantly, I am seeing new hairs growing out on the front. Some of the hairs are vellus, but many of them appear to be terminal black hair coming out. The new hairs starting coming out about 1-2 weeks ago.

                      As for any sides I haven't experienced any. My body weight is unchanged and everything in the pants is functioning normally.

                      I'll update you guys again at the 3 month mark.
                      Great post, keep updating us.
                      I'm waiting for mine to arrive.

                      Comment

                      • brunobald
                        Senior Member
                        • Jul 2013
                        • 172

                        Im good for $10 to test free DHT in sombody using s-equol.

                        This could be an effective treatment, judging by some of the comments it appears to do something. Tests show it does not effect serum DHT so the next logical step is to test free DHT. We complain about scientists but we rarely ever take things into our own hands, lets crowdfund this experiment, we are talking buttons to do this.

                        Comment

                        • cthulhu2
                          Member
                          • Jun 2014
                          • 71

                          Originally posted by kaz007
                          I guess the next step is for Adaaku and Itch to take a free DHT test. Adaaku, why don't you create a PayPal account and post the email address here? Each person giving $10 to $20 each should quickly get the test funded. Guys, skip that $6 Starbucks coffee a couple of times for science and your hair!
                          I too would be happy to make a contribution in the name of science(bro science).

                          Comment

                          • PinotQ
                            Senior Member
                            • May 2010
                            • 188

                            My second blood test is back. As I am on Finasteride, my values don't have much relevance to those taking only equol, however, on a relative basis my results may give a few more clues as to what equol is doing.

                            The normal ranges for each item are Total Testosterone 250-1100 ng/dl; Free Testosterone 35-155 pg/ml; Total DHT 30-85 ng/dl; Free DHT 1-6.2 pg/ml; SBHG 22-77 nmol/L

                            While I was on 144 mg per day of equol Total and Free Testosterone were 390 & 56.9 respectively; Total & Free DHT were 9 & .66 respectively; SBHG was 35.3

                            After I went off of equol for 14 days, Total and Free Testosterone were 627 (up 61%) & 114.3 (up 101%) respectively; Total & Free DHT were 12 (up 33%) & 1.012 (up 55%) respectively; SBHG was 41 (up 16%)

                            On a percentage basis, equol appeared to have the most noticeable impact on Total and Free Testosterone . Not sure if that really means anything since the results remained In Range.

                            On a percentage basis, equol did appear to have a significant impact on Total and Free DHT. However, given my numbers are either out of or at the low end of the normal range to begin with (because I am on Finasteride), I'm not sure how much that really means either. Also, keep in mind that I am on a mega dose of equol. Therefore, it may be that very large doses of equol are sequestering a relatively small amount of DHT. It would be interesting to see the comparative impact on someone that is not on Finasteride.

                            Given what one of the patent holders told me (see post above), it may be that the most effective use of equol would indeed be as a topical. I hope this helps.

                            Comment

                            • bananana
                              Inactive
                              • Feb 2012
                              • 525

                              I've started taking approx. 0.5 grams of equol daily. (2X 0.25 )
                              I have enough for 150-200 days. I'll give you my detailed report on any changes.

                              Comment

                              • Shinobi
                                Member
                                • Oct 2014
                                • 34

                                Originally posted by PinotQ
                                My second blood test is back. As I am on Finasteride, my values don't have much relevance to those taking only equol, however, on a relative basis my results may give a few more clues as to what equol is doing.

                                The normal ranges for each item are Total Testosterone 250-1100 ng/dl; Free Testosterone 35-155 pg/ml; Total DHT 30-85 ng/dl; Free DHT 1-6.2 pg/ml; SBHG 22-77 nmol/L

                                While I was on 144 mg per day of equol Total and Free Testosterone were 390 & 56.9 respectively; Total & Free DHT were 9 & .66 respectively; SBHG was 35.3

                                After I went off of equol for 14 days, Total and Free Testosterone were 627 (up 61%) & 114.3 (up 101%) respectively; Total & Free DHT were 12 (up 33%) & 1.012 (up 55%) respectively; SBHG was 41 (up 16%)

                                On a percentage basis, equol appeared to have the most noticeable impact on Total and Free Testosterone . Not sure if that really means anything since the results remained In Range.

                                On a percentage basis, equol did appear to have a significant impact on Total and Free DHT. However, given my numbers are either out of or at the low end of the normal range to begin with (because I am on Finasteride), I'm not sure how much that really means either. Also, keep in mind that I am on a mega dose of equol. Therefore, it may be that very large doses of equol are sequestering a relatively small amount of DHT. It would be interesting to see the comparative impact on someone that is not on Finasteride.

                                Given what one of the patent holders told me (see post above), it may be that the most effective use of equol would indeed be as a topical. I hope this helps.
                                This is very interesting.. Balding people always have low level of serum DHT. Instead saliva DHT is very high. Thanks to share your result with us

                                Comment

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