Aderans hopefully soon

[UK_]

We have already established that the Aderans reps at the international meetings will not be discussing their trials (and they never have). Further, what was released today is all of the information to be discussed at the meeting (they issue it beforehand).

Can you provide me the source of information that shows Aderans will not be discussing their trials at the International Investigative Dermatology Meeting? Also, I'm a little confused, are you saying the shareholder release (what you just linked me) is all of the information to be discussed at the International Investigative Dermatology Meeting in May?

[Pentarou]

Half of the time I worry whether AGA hair loss can ever be treated.
What we do have doesn't work well at all, those few drugs weren't even designed for hairloss, and it's be over twenty years with nothing new, apart from Avodart, which is off-label, unproven and riskier than finasteride.

[Thinning87]

Well, yes, true. Lots of possible reasons behind that. Fake substances, inappropriate chemical vehicles, substances which are too weak (cetirizine), it's all failure by amateurs, often well meaning amateurs. Not expecting a cure from all this, but some new treatments that could be bought in any regular pharmacies, that would be nice.

yeah well I agree that that would be nice...

[Pentarou]

I don't know that but keep in mind all we have seen is the failure (and some positive results in some cases) of a lot of home made chemical solutions...

Well, yes, true. Lots of possible reasons behind that. Fake substances, inappropriate chemical vehicles, substances which are too weak (cetirizine), it's all failure by amateurs, often well meaning amateurs. Not expecting a cure from all this, but some new treatments that could be bought in any regular pharmacies, that would be nice.

[Thinning87]

I don't know that but keep in mind all we have seen is the failure (and some positive results in some cases) of a lot of home made chemical solutions... I don't think that's very meaningful, at the same time we haven't heard much from Cots so I really don't know, although you can't expect the guy to find a cure in a year and a half.

I think there's a lot of positive stuff out there and the best thing to do right now is maintain (if you can tolerate finasteride) while working to improve your life in other ways, which doesn't mean being at the gym everyday, but committing yourself to other things that make you passionate and keep you active, whatever they may be for you.

I have also trimmed my head to nearly a zero in January and I have been able to accept my self that way. It really wasn't so bad, I didn't get as many looks from girls but I could tell some definitely liked it.

Another thing I find great is going for a swim at 5:30 AM every day (quick 20 laps), and then doing sauna and cold showers. I feel amazing, work really well, and then have the best sleep at night, which really helps.

Try new things: try to meet new people and do new stuff, I joined a soccer league and play every Sunday for example, and met some new people which is interesting. Break away from the routine, try new bars/pubs/clubs, and always say yes when you have a chance to hang out in different environments. I have a friend who has been balding since when he was 18 and he's gonna take me speed dating lol...

Also get out there and definitely hit on girls! I know it may sound illogical, but when I trimmed I tended to care less about a girl's reaction because I felt like I was the way I was and she could go **** her self if she didn't like it. I went through my phone book, selected 4 girls to have a date with to see their reaction to my new look, and one of them ended up becoming my girlfriend while another one still shows interest...

I also have been working really well in the office, being the first one in (as I get to work at around 7 AM every day) and dedicating my self to my career. I already locked in a new higher paying-job that will start in a couple months at one of the best companies in my industry...

The point is, shit happens but if you react positively it might be a blessing in disguise as you might stabilize your life with respect to other things that matter to you... and then there's always the chance that they actually find a way to make us look decent relatively soon... not saying a cure, but something that will have some decent effect... and then later on a cure, since as I have repeated here many times I don't know how all this research that is yielding good results can lead to nothing.

[Pentarou]

So you think that we were far too premature and unrealistic in our expectations for prostaglandin treatments? I hope that is right.

[Thinning87]

Yeah man it's too bad it didn't turn out into what we all thought but there is plenty of research being carried out right now and I can't see how every single one of these advanced studies can lead to nothing.

Remember stem cell research was in its infancy just a few years ago and look at the studies being posted constantly nowadays.

[Pentarou]

I remember a year ago when Prostaglandins were the thing, and people were scrambling to find existing formulas that could be used to treat hairloss.

Didn't work out, it seems.

[Thinning87]

No - he's a serious guy in a serious university - it's just not that easy, but they continue to try, and that is good enough right now.

[Pentarou]

Cotsarelis is still working, check out the list of presentation abstracts planned for the conference

Not working on Prostaglandins then? I'm wondering if Cots is just a patent troll at this stage.

[Thinning87]

http://www.nature.com/jid/journal/v133/n1s/full/jid201397a.html

[Thinning87]

Honestly, at this stage unfortunately I wouldn't be surprised if ARI goes the way of Follica.

Cotsarelis is still working, check out the list of presentation abstracts planned for the conference

[Pentarou]

The Aderans parent company published the yearly synopsis for their shareholders meeting today. It didn't even mention the Aderans Research Institute (in prior years, ARI is usually mentioned). That seems like a bad sign. I wish Spencer would get on this. He said over a year ago that Washenik agreed to talk to him, and continually intimates that progress is being made in this area, but honestly I think he's wrong about this one. ARI, by all objective and observable measures, is not a healthy company. There is no official indication that the technology is headed for Phase 3, and Washenik has been presenting the same data (from the first series of clinical studies) since June 2010. Spencer, can you throw us a lifeline or give us a clue here? Things aren't looking good... I wish Dr. W would grant an interview or ARI would publish a press release or something.

Honestly, at this stage unfortunately I wouldn't be surprised if ARI goes the way of Follica.

[Thinning87]

You're asking me to prove a negative, which is essentially impossible. There is no way to guarantee that the engjre structure of the meeting may change at some future point. Having said that, only one notice of the shareholder meeting is oublished each year (here: http://www.aderans.com/english/ir/library/meeting.html). Last year's at least mentions commercialization, etc. This one does not. It's not a difficult inference to make.

mhmhm I don't know if this means the end of ARI, but this certainly isn't a positive sign.

I think their recent discovery may prolong their phase 2 studies as they have to improve efficacy (assuming what we have discovered about their efficacy results in this forum is actually true).

I doubt they'd just completely shut down after all these years and this knowledge, but who knows, stuff like that happens all the time, if a division of a company is not going to yield reasonable ROI it must be shut down, it's just business basics

[Joker]

You're asking me to prove a negative, which is essentially impossible. There is no way to guarantee that the engjre structure of the meeting may change at some future point. Having said that, only one notice of the shareholder meeting is oublished each year (here: http://www.aderans.com/english/ir/library/meeting.html). Last year's at least mentions commercialization, etc. This one does not. It's not a difficult inference to make.