Taking .05mg finasteride effective with fewer side effects?
Collapse
X
-
win200
You can make up your own mind if someone had working links to wherever "buddha" (author of the webpage linked in post #1) got his Merck data. It's too late right now for me to search through journals, sorry. I will however give you a summarise to the best of my memory (though you should note - i'm not sure i've seen the ostrogen data the dude quoted).
The study shows 0.05mg inhibits very little less scalp DHT than 1mg (a few %, whilst inhbiting 20% less serum DHT (the big question - less chance of side effects? Not that simple based on pharmacological accumulation of drugs meaning dose could be useless), and causes less increase in testosterone (another big question - less conversion to oestrogen and chance of developing gyno? Another not simple question, as testosterone might balance out long-term, in addition to other factors).
On the face of it, the data seems significant. HOWEVER, you're welcome to disagree, but the data to me seems debunked by the fact that the 0.2mg dose did not provide "expected" values for these 3 measures above between 0.5mg and 1mg dose. Thus, can we really draw any reliable conclusions from the data provided?
To summarise, 0.05mg is much cheaper (20x), MAY have a reduced chance of causing side effects. However, it inhibits DHT slightly less, and trying to get a 0.05mg dose from a 1/5mg pill is highly inconvenient and likely inaccurate.
Also important, Desmond (a self-reported pharmacologist - no offence Desmond, I've got to stay objective here!) mentioned the difference between a plasma half-life (the ~6 hours usually reported for finasteride), and a biological half-life (what we are actually interested in - how long the pharmacological effects of a drug remain before another dose is required). Correct me if i'm wrong Desmond, but based on some studies of a single dose of finasteride given to people (again, you'll have to get these yourself I'm afraid), along with how half-lives of drugs alter with prolonged use (the longer you take a drug, the more build-up and the longer clearance takes), YOU SHOULD DOSE BEFORE EVERY 3RD DAY.
Personally, I'm just taking any dose I see fit, every other day.
/sleepComment
-
I'd stick with it for a while and monitor your sides
Hey Desmond what do you think about dissolving the fin tablet in an alcohol? Also, could a 1mg fin pill be cut 8 ways by a pill cutter? I may just take little bites off the pill, I recall a member saying he still got mild sides from doing that. For me, as long as I take between 0.05-0.2 mg every 3-5 days I would be good. Im using RU on the front of my scalp and hairline so all I am really hoping for with fin is some stability in the crown and to knock my DHT down a little.Comment
-
fair enough, plus Allergan(bimatoprost) is fairly close to release so that may be a good alternative growth factor down the line if you're not interested in Min.(not super close, but 2 years or so.)
The best anyway we can do right now is maintain or slightly thicken anyway, Min doesnt exactly do all that much, but at least we can do something now, couldnt say the same thing 15 years or so ago.
I actually managed to get my hands on the Allergans Phase I results for Bimatoprost in AGA. They found that 60% of patients did show signs of pigmentations on their skin. So, I guess I was right
This stuff would be useless once Histogen comes out!Comment
-
win200
Also important, Desmond (a self-reported pharmacologist - no offence Desmond, I've got to stay objective here!) mentioned the difference between a plasma half-life (the ~6 hours usually reported for finasteride), and a biological half-life (what we are actually interested in - how long the pharmacological effects of a drug remain before another dose is required). Correct me if i'm wrong Desmond, but based on some studies of a single dose of finasteride given to people (again, you'll have to get these yourself I'm afraid), along with how half-lives of drugs alter with prolonged use (the longer you take a drug, the more build-up and the longer clearance takes), YOU SHOULD DOSE BEFORE EVERY 3RD DAY.
Personally, I'm just taking any dose I see fit, every other day.
/sleepComment
-
Got good news and bad news. I got my fin today which is the good news, but the bad news is - the pills are in capsule form. The pharmacy where I filled my Rx compounds the 5mg fin. Meaning they crush the tablets and fill the tablets into 1mg pre-measured capsules. I'm sure you're asking what's the big deal - now I have to start with 1mg fin compared to the 0.5mg fin.
What do you guys suggest?Comment
-
Comment
-
Made it my self
Made it bought a pill crusher a funnel put 10 mg in to 60 mls of spectral dnc, to early to say things are looking good,also I'm going to buy proscar a d up to 25 mg to 60 mills,also guys check out cutting edge future treatments conpecia people having success with topical hay fever tablets blocking pgn2!!Comment
-
we do need more people to join in though, chemists, pharmicists, the more opinions the better.
No guarentees this product will actually work, but if it's safe to use, it's worth a try.Comment
-
Either way I was never all that excited for BIM, seemed to me like a transition drug/topical until something better comes out a couple years later.Comment
-
yes I know this is a dead tropic, but please someone respond. I just turned 22, took fin for about a year and didnt see a problem, now I feel like my erections are not there! I switched over to 1mg tablets of Fin and still see this problem with my erection. I have just for the first time tonight cut the 1mg in half and took half! after reading every page I decided to cut the 1mg into 4 pieces and take one every mon,wed, fri. no matter how little I take this stops my hairloss so I'm not afraid of losing hair, I'm afraid of losing my manhood! do you guys recommend trying this new regiment of mon,wed,fri? also I don't take any minox, what's the best one? thanks and someone please help me! hopefully one of the pharmacists or someone who is just trying to help this 22 year olds life :/Comment
Comment