The fact is, the "cure for hair-loss" has been "five or ten years away" for at least as long as I can remember — it was the general feeling in the air certainly as far back as the 1990s. Every now and then, someone has successfully cloned something in vitro, or grown a hair on the back of a mouse, and The Balding have gotten their hopes up that the answer has been unearthed and that it's now only a matter of time before clinical trials are completed and the F.D.A. approves this marvelous new therapy to safely, effectively, and permanently reverse androgenic alopecia. The thing is, clinical trials are what determine the safety and efficacy of a drug, and all the preemptive rejoicing of people around the prospect of something just makes them bitter when, year after year, "promising" old studies are never again heard from, and new ones crop up that sound very much like those forgotten.
Early in 2011, we're all very excited about Histogen and Aderans (some of us, maybe about Trichoscience, as well). Truthfully, Histogen's H.S.C. has completed stage 1 trials — most drugs that pass stage 1 testing go on to fail by stage 3. Optimism is nice, but hopes that scrape the heavens are likely to shatter to shit if they fall. Given the track-record this field of study has, let's at least practice very, very cautious optimism. As for Aderans and Trichoscience, they're simply companies that are trying to accomplish what many others already have tried, and failed, to; I don't believe there's any more reason to be excited about them than one would be upon hearing, "People would like to cure baldness."
Finally, regarding ACell, I'm hopeful, yes, that it might give some credence to the notion of "autocloning" (which, of course, is not a "cure" for balding, but could greatly facilitate its current surgical treatment of transplantation), but Dr. Cooley's images have hardly knocked me off my ass. With many of them, if I hadn't read the caption, I'd've never guessed I should feel ACell effected a positive outcome (and, sorry, "images don't do it justice; you have to see it, in person" is not encouraging). Further, his work, to date (March, 2011), has given us no meaningful numbers. How many F.U.E. extractions were made (with transection), and how many grew back, without use of ACell? How many did, with ACell? How many plucked hairs grew in the recipient area, without ACell? With ACell? How many plucked hairs regrew in the donor region, without Acell? With? Ultimately, I'm unsure how much sense it makes to be euphoric about this product based on uncertain images and no useful quantitative data. Now, don't get me wrong: I'll be thrilled if it work out — I just don't believe it's very sensible for us all to just yet hold our breaths, once more...
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Who is talking about Histogen here? I am referring to the use of Acell, not Histogen's work which is totally separate to this discussion
Autocloning works on a small scale? - Fair enough, so does Emu Oil n' Saw Palmetto; my point is that there is nothing to get excited about until you can match/better the likes of Propecia/Minoxidil otherwise they wont even market this technique. Nobody here can show me results, and your assumption that the results will suddenly start flying across these boards in some kind of wild frenzy due to the introduction of a better plucking "technique" is at least - a very very long shot, given what we have seen so far.
The basis of the current results rests on the efficacy of the the actual compound, not the plucking technique, I am here to see if ACELL grows hair, and so far, I have seen nothing convincing, that is literally as simple as it gets. Histogen is a totally different story, I am one of the most negative people when it comes to hair loss promises, but Histogen is probably the only company I can honestly say I hold genuine promise/excitement for.Leave a comment:
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Ok guys then lets just agree that we dont agree.
I think my bubble of optimism is very cosy and comfortable :-) You just have to look at one thing, what makes hairloss dicktits? Right when it affects our psyche.
And i wont let that happen because those kind of things wont go away easy, even when you have your hair back in the near future, just simple as that.
Iam optimistic for several reasons
1) Autocloning works on a small scale so with improvement this can be made even more succesfull
2) Even Dr Coles really hardcore "bashing" has gone to moderate
3) People begin to understand the real problems of hairloss or what causes it its not the same old "Grab Minox and you can enjoy it" story anymore
4) They even created artificial hairfollicles a somehow "new" thing
5) Histogen created cosmetically significant regrow (permanent after one year) and yes i believe their words and only their words, iam stupid right :-)
6) More clinics are experimenting with acell
Well but thats just my opinions and no i dont think that we are all on the same side, i highly doubt it.
Anyway what you call "No progress" is very easy explained, hair doesnt grew ten centimeters a day
But to make things short, should i really discuss with people who call me "stupid" for believe in something "without evidence" (the without evidence part is btw very funny)
So end of story iam more optimistic and enjoy my life while you guys do what suits you best ^^Leave a comment:
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We are all on the same side here, literally all of us, a debate on these forums is never anything personal.
I'd too love to sit in the bubble of optimism regarding the developments currently being made with regard to Acell, but the harsh truth is that barely anything is happening...Leave a comment:
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How can you be so stupid to base your opinions on no evidence?
Dr Cole's picture is the only piece of evidence that when I look at it I can't immediately find 15 questions that doubt whether its real or not. So that is all we have, 1 photo.Leave a comment:
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To Quote the Dude : "Thats your opinion man, thats your opinion"
You say Acell failed, i say it doesnt. Lets agree we dont agree
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Yes, that's all we are doing, bolstering our "opinons" and until I can see what I asked for (solid regrowth of new terminal hairs in donor in c90%+ of patients) I continue to ask the question: where is the progress? Acell has clearly not lived up to its initial hype, it has not produced the results to date. Regarding your comment about "improving efficiency over time" (by the way we are looking at efficacy not efficiency) what type of method, process or component in this procedure do you believe will bring us from a stage of barely any progress/no results to a stage that can better the results of the likes of Histogen/Aderans or even Propecia?
Any ideas? I really doubt twisting pulling or yanking hairs out in any which way possible will do it, the compound does not work, it has failed. Move on.Leave a comment:
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I dont think that i have to justify my personal impressions here to you guys. Lets stick with it here. You guys are more pessimistic and iam more optimistic but i dont wanna convince you to become optimistic because its your opinion.
@UK: Your statement ".....an ad hoc one-off transplant that regrew a few fine hairs in donor isnt a result....." is pure effin comedy gold.
This technique is in its beginnings and provided some "fine regrown hairs in the donor are" so those results can obviousy be made more efficient.
But dont discuss this its fruitless because you guys have your opinion and i have mine, lets agree that we dont agreeLeave a comment:
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Well but i do because there is obvious progress so thats my opinion, to be more optimisticLeave a comment:
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Ok seems Acell works to well, thats of course very good to hear but sad that you cant inject it in the frontal area.
Good job so far iam really looking forward to 2013Leave a comment:
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