ACell, a Current Review of Applications in Hair Transplant Surgery

[HairTalk]

Thanks for the Feedback Dr Hitzig, its sometimes good to get a backup when people really starting to crawl under my skin in terms of the overly negative thinking"

I have some questions, hope you answer them.

1) Do you have plans for going one step beyond like performing FUE with the twist to "transsect" hairs that they will grow back in the donor area and also in the recipient area (this could solve the time and tedious problem to some point)

2) Have you ever tried different states of hair characteristics during the plucking session like

- wet hair vs dry hair
- medium trimmed hair
- tweeze them clockwise
- tweeze them counter clockwise
- curl them around the tweezer like spaghettis and then pull the tweezer southward
- etc
- reprogrammed NeoGraft machine ( i dont think its beneficial to FUE but could be for plucking) which could perform the plucking part consitently

I am just thinking abou those things because more often its just a little detail nobody has accounted so far which decides the important factors

What difference do you feel the nature of the plucking might make with regard to the procedure? It's what's at the end of the hair shaft that's of concern, and I fail to see how "twisting clockwise" vs. doing so counter-clockwise — or curling the hair, or trimming it, or wetting it — would have any bearing on the result.

[RichardDawkins]

Thanks for the Feedback Dr Hitzig, its sometimes good to get a backup when people really starting to crawl under my skin in terms of the overly negative thinking"

I have some questions, hope you answer them.

1) Do you have plans for going one step beyond like performing FUE with the twist to "transsect" hairs that they will grow back in the donor area and also in the recipient area (this could solve the time and tedious problem to some point)

2) Have you ever tried different states of hair characteristics during the plucking session like

- wet hair vs dry hair
- medium trimmed hair
- tweeze them clockwise
- tweeze them counter clockwise
- curl them around the tweezer like spaghettis and then pull the tweezer southward
- etc
- reprogrammed NeoGraft machine ( i dont think its beneficial to FUE but could be for plucking) which could perform the plucking part consitently

I am just thinking abou those things because more often its just a little detail nobody has accounted so far which decides the important factors

[Gary Hitzig MD]

Autocloning

Remember guys that Dr. Kim showed well before me that if you cut out a complete hair (FU) then transect it below the bulb, and then transplant both "pieces" to the same person (in his case his arm), he grew 2 hairs.
This is what started me on the road to "Autocloning". Other studies showed that rat whisker hair would do the same whereas body hair (on rodents) would not. When you try laser hair removal of body hair it is not a problem; however beard laser hair removal just doesn't work well at all. I postulated that beard hair is like weeds- they are stonger than body hair. This proved itself to be true in the early trials. Despite this, there was something missing to help stabilize the "take" in autocloning. ACell seems to be that missing puzzle piece.
Richard has really got it in terms of understanding that we are nearing the answer but need to improve the method. Your suggestions help fuel our ideas.

[RichardDawkins]

Do you refer to the 2007 fact sheet? Well i can almost clearly say, that those autocloned hairs are an indicator for the new born follicle from donor material. Because if you see like this

"How possible is it, that one single plucked hair could create or animate other follicles or cells to create other hairs in an area where DHT is "deadly" for hairs"

Another possible aspect could be, when you lance the skin in the recipient are, you cause damage and at this point when tissue gets repaired it "accidentally" uses cell material from the donor area.

Both explainations could show why the hairs Dr Hitzig plucked years ago, are still cycling.

Also its high likely that the moment you pluck the hair, different cell material is still present also DP material and this is transplanted in the recipient area.

And thanks to acell as an enhancement its pretty quick "multiplying"

But all this doesnt change the fact that a lot of efficancy has to be done to make this technique faster and les labor intensive.

[plopp]

Have I understood it right if you say that the dp in the recipient is an exact replica of those in the donor? Any sources? Cooley has shown pics before demonstrating a certain degree of recipient dominance, so I'm not sure that's entirely true.

[RichardDawkins]

When your plucked hair grows, it grows from the FULL material of the dht resitant here itself. The hair itself creates its surrounding as you know the cells are formed then.

Cause even if this hair actually connects to a DP, the DP will take this genetic material especially when its dormant. The DP is actually capable of stimulate other cells to develop hair follicles. Thats why sometimes autocloned hairs come up.

But the key is the material from the hair which connects to the dp. The material around the hair itself has to be sufficiant enough to create another follicle, thats why thie technique right now is tedious.

And those autocloning hairs are nothing other the somethings direct copies of the follicles where the hair was plucked.

You see how strong the genetic material around the hair is it also contains the information " Is my origin a single hair follicle or a multi hair follicle"

[plopp]

Ok some people here doubt that plucked hairs actually survive and are dht resistant. We all know that the most important thing is the follicle right.

Then just look at this picture and search where exactly the "follicle" is and you got your answer if you compare the fotos of plucked hairs with this picture :-)

http://en.wikipedia.org/wiki/File:Skin.jpg

Enjoy ^^

Nice one Rich

One thing that bothers me though in terms of dht resistance is that the dermal papilla, which is waht actually controls hair growth (as is my understanding), is derived from the recipient. The plucked hair - correct me if I'm wrong - only contain the root sheath (i.e. epithelial cells). I'm no MPB expert, but it seems to me that the dermal papilla if anything should be the DHT sensitive part of the follicle.

Nevertheless, even if dht resistance turns out to be a problem, I think autoplucking can find its way as a repair procedure (let's just hope the scar issue gets resolved..)

[RichardDawkins]

the problem is simply and sad : Yes its working and could solve our problems but the how to be efficient side is another story

[SilverSurfer]

What is hard to understand is why all of the sudden the docs are not giving anymore feedback on their findings and are trying to build some sort of mystery around the subject.

Yes I get it, the business perspective; but if it is working, why aren't succesfully treated patients with the autoplucking coming forward?

[SilverSurfer]

I hope that's right

[RichardDawkins]

Ok some people here doubt that plucked hairs actually survive and are dht resistant. We all know that the most important thing is the follicle right.

Then just look at this picture and search where exactly the "follicle" is and you got your answer if you compare the fotos of plucked hairs with this picture :-)

http://en.wikipedia.org/wiki/File:Skin.jpg

Enjoy ^^

[KeepHoping]

I've seen those, I mean pictures of all the people with good results that have been reported by these doctors. I don't mean to sound rude, I just don't understand why we aren't seeing more before and afters, makes no sense to me, would only boost their profits with the amount of patients it would bring in.

[montrose]

There a few pics of what they call "robust growth"

http://www.***************/hair-loss...ell-matristem/

substitute regrowhair

[KeepHoping]

No pictures?

I've asked the question before but I'll ask again. With the reports of "Robust Growth" and seeing cloned hairs appear after transplanting why would they not show the pictures of the recipient areas? In theory, if the growth is robust and they are actually getting more hairs then transplanted by a huge margin why would they not be all over the place?

[RichardDawkins]

I also dont think that his outcome was negative because 7 days ago he said "Many grow" but the rest of his posting was short.

Maybe he is used as one of the test patients for major plucking sessions.