Finasteride: Crushing pills, "parachuting" low dose, pill coatings

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  • BigThinker
    Senior Member
    • Oct 2012
    • 1507

    Finasteride: Crushing pills, "parachuting" low dose, pill coatings

    So, this may come off as asinine or naive, but I'm willing to open myself up to criticism here.

    Is it feasible to crush a 5 mg pill of finasteride and, using a high-sensitivity electronic scale, portion the pill into very low doses (0.25 mg, let's say), and "parachute" them? For those unaware, parachuting is the act of taking a drug in powder form, wrapping it in a small amount of toilet paper, and consuming like a normal pill (typically chased with water).

    I know that the portioning aspect is viable. What I'm concerned about is if crushing the pills, which is effectively mechanical digestion, causes them to absorb too early or too easily into the blood stream (if that's even a prospective concern). Pills typically have coating, and I'm not sure if the coating is purely to keep from topical absorption or to aid in the delay of the digestion.

    I know it's coming off as shady using terms like "parachuting", because it is typically associated with illegal, controlled substance consumption. But, please use integrity with any responses and keep nauseating politically correct responses at bay (unless they are based on concrete scientific evidence, of course.) My main interest is to explore options for micro-dose consumption, and I can't imagine it very easy to cut a 5mg pill smaller than quarters.

    Regards and thanks for consideration.
  • Aames
    Inactive
    • Nov 2012
    • 626

    #2
    May I ask why you are interested in microdosing in the first place? I've seen countless people recommend this but never explain why. Since the DHT inhibition isn't incredibly different between 0.25 and 1 mg, there's no point in cutting pills other than to save money? I doubt 50% vs 70% DHT inhibition would make a difference in you getting sides. It's just a crap shoot imo.

    Comment

    • BigThinker
      Senior Member
      • Oct 2012
      • 1507

      #3
      Originally posted by Aames
      May I ask why you are interested in microdosing in the first place? I've seen countless people recommend this but never explain why. Since the DHT inhibition isn't incredibly different between 0.25 and 1 mg, there's no point in cutting pills other than to save money? I doubt 50% vs 70% DHT inhibition would make a difference in you getting sides. It's just a crap shoot imo.
      I've just seen so many contradicting testimonies and science-based evidences that I'm really confused on the efficacy/sides probabilities with respect to biological gradient.

      Due to this, I'm thinking I would prefer to error on the side of caution. I realize I'm being hyper-analytic with this, but I value my health and choose to be as educated as possible when self-medicating.

      If you have any literature on hand to link, I'd be not only interested, but grateful.

      Comment

      • Aames
        Inactive
        • Nov 2012
        • 626

        #4
        Google "finasteride dht inhibition by dose" and look for the topic on hrn (can't link as it's censored). The topic is called "Finasteride: dosage, frequency & conception."
        Check out that link, it has a few graphs that show the DHT inhibition by dosage. Essentially, 0.2 mg inhibits almost as much as even the 5 mg dose does. I imagine it's always a good idea to taper onto medications but I just don't see how doing so would minimize potential sides. I guess it really doesn't matter then in terms of hair retention either, given the fact that small doses are still effective. If you want to taper on, I would just quarter the damn things and be done with it. No need to crush them and parachute.

        Comment

        • elnino
          Senior Member
          • Sep 2012
          • 149

          #5
          Originally posted by BigThinker
          So, this may come off as asinine or naive, but I'm willing to open myself up to criticism here.

          Is it feasible to crush a 5 mg pill of finasteride and, using a high-sensitivity electronic scale, portion the pill into very low doses (0.25 mg, let's say), and "parachute" them? For those unaware, parachuting is the act of taking a drug in powder form, wrapping it in a small amount of toilet paper, and consuming like a normal pill (typically chased with water).

          I know that the portioning aspect is viable. What I'm concerned about is if crushing the pills, which is effectively mechanical digestion, causes them to absorb too early or too easily into the blood stream (if that's even a prospective concern). Pills typically have coating, and I'm not sure if the coating is purely to keep from topical absorption or to aid in the delay of the digestion.

          I know it's coming off as shady using terms like "parachuting", because it is typically associated with illegal, controlled substance consumption. But, please use integrity with any responses and keep nauseating politically correct responses at bay (unless they are based on concrete scientific evidence, of course.) My main interest is to explore options for micro-dose consumption, and I can't imagine it very easy to cut a 5mg pill smaller than quarters.

          Regards and thanks for consideration.

          i have read a lot of reports that say .25 is as effective as 1mg with the advantage of fewer side effects, however i honestly dont know how concrete these reports are. im currently cutting proscar in 5s and thats tricky enough let alone 8s or what ever man! but timescale wise, i would say give yourself the small doseage for a month or two and if nothing, gradually increase because whether people say .25 or not, i STILL would rather taking the recommended dose of 1mg.

          Comment

          • Ktownmatti
            Member
            • Oct 2012
            • 81

            #6
            I'm assuming your reasoning here is simply to save money as you could easily buy 1mg propecia tablets and cut them into quarters with a razor (what i did when tapering on)
            I don't see anything wrong with your idea other than it seems like a lot of work to save 15 bucks a month

            Comment

            • BigThinker
              Senior Member
              • Oct 2012
              • 1507

              #7
              Originally posted by Ktownmatti
              I'm assuming your reasoning here is simply to save money as you could easily buy 1mg propecia tablets and cut them into quarters with a razor (what i did when tapering on)
              I don't see anything wrong with your idea other than it seems like a lot of work to save 15 bucks a month
              You're exactly right. And, I've actually recently regretted ordering 5 mg instead of 1 mg for that reason. It might be reasonable for me to buy 1 mg to quarter, and save to later utilize the 5 mg.

              Comment

              • nativer
                Member
                • Aug 2012
                • 36

                #8
                I feel your idea is sound. From everything I have read, I would not think crushing up the pill somehow dilutes or makes the medication ineffective.

                With the sides.. again from the forums i have visited. You either get the sides or you do not. If you do not, Joy!

                If you get them, then no amount of reduction in the medication makes them go away. You also can not "power on" through the sides. If you get sides on Finn, stop put it away.

                OR you can try something that has not been done. Like 1mg a week, or 1mg every two weeks. Or .25 a week or .25 every two weeks. I have yet to read anyone that experienced sides trying that.

                Comment

                • BigThinker
                  Senior Member
                  • Oct 2012
                  • 1507

                  #9
                  Originally posted by nativer
                  I feel your idea is sound. From everything I have read, I would not think crushing up the pill somehow dilutes or makes the medication ineffective.

                  With the sides.. again from the forums i have visited. You either get the sides or you do not. If you do not, Joy!

                  If you get them, then no amount of reduction in the medication makes them go away. You also can not "power on" through the sides. If you get sides on Finn, stop put it away.

                  OR you can try something that has not been done. Like 1mg a week, or 1mg every two weeks. Or .25 a week or .25 every two weeks. I have yet to read anyone that experienced sides trying that.
                  I'm definitely starting with intermittent doses. My hair quality is good enough that I have time to taper on extremely slow. Further, I value my libido and boners.

                  Comment

                  • baldesswonder
                    Member
                    • Dec 2012
                    • 50

                    #10
                    Originally posted by nativer
                    I feel your idea is sound. From everything I have read, I would not think crushing up the pill somehow dilutes or makes the medication ineffective.

                    With the sides.. again from the forums i have visited. You either get the sides or you do not. If you do not, Joy!

                    If you get them, then no amount of reduction in the medication makes them go away. You also can not "power on" through the sides. If you get sides on Finn, stop put it away.

                    OR you can try something that has not been done. Like 1mg a week, or 1mg every two weeks. Or .25 a week or .25 every two weeks. I have yet to read anyone that experienced sides trying that.
                    no crushing tablets does not effect the potency of the drug

                    Comment

                    • nativer
                      Member
                      • Aug 2012
                      • 36

                      #11
                      So here is what you do. Crush up Propecia and then smoke it.

                      Any record of anyone doing this
                      1mg or 0.25 a week
                      1mg or 0.25 every two weeks
                      1 mg or 0.25 every three weeks.
                      1 mg or 0.25 once a month.

                      Comment

                      • d2001chen
                        Junior Member
                        • Nov 2012
                        • 24

                        #12
                        Some doctors say that the effects of propecia (1mg finasteride) stay for 48-72 hrs. So they recommend taking it on alternate days instead of daily. That is alternatively to taking a smaller dose everyday.

                        Comment

                        • dex89
                          Senior Member
                          • Jul 2012
                          • 808

                          #13
                          Originally posted by nativer
                          So here is what you do. Crush up Propecia and then smoke it.

                          Any record of anyone doing this
                          1mg or 0.25 a week
                          1mg or 0.25 every two weeks
                          1 mg or 0.25 every three weeks.
                          1 mg or 0.25 once a month.
                          Smoke it? haha what's next, snorting it?
                          Originally posted by d2001chen
                          Some doctors say that the effects of propecia (1mg finasteride) stay for 48-72 hrs. So they recommend taking it on alternate days instead of daily. That is alternatively to taking a smaller dose everyday.
                          Really, do have any proof?

                          Comment

                          • dex89
                            Senior Member
                            • Jul 2012
                            • 808

                            #14
                            douple post.

                            10char

                            Comment

                            • d2001chen
                              Junior Member
                              • Nov 2012
                              • 24

                              #15
                              Dex89,

                              I think Dr. Cooley recommends propecia on alternate days.
                              I can understand you doubting it, and I too would like some clarification on this.
                              I am surprised why this has not been mentioned in the forums till now.

                              Does anyone else in the forums have more information on this?

                              Comment

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