RepliCel Reports Progress on Shiseido Technology

[Thinning87]

I could go, it's near my house. But I highly doubt it's worth it.

However if you want the experts could prepare some questions for me to read and I could ask if I have the chance to. Kind of what Desmond did in Korea, I can record the answers with my phone and post it on YouTube.

We might even make a thread about it in the cutting edge directory as not many people view this thread

[hellouser]

Someone should go attend this meeting

There's gotta be someone in California that can go to the presentation. Truthfully, I don't think anything NEW will come out of the presentation.

[hairlosskills]

Someone should go attend this meeting

[sascha]

Hello guys. Since the CEO of replicel David Hall is travelling around like crazy, I think a regular caller of the BaldTruth should call in and ask Spencer what kind of news he was supposed to share with us. Somebody mentioned in a comment, that some time ago Spencer Korben said something like this. By the way, we probably will get the next piece of news about Replicel on the 7th October. If somebody is interested in attending the meeting: http://www.replicel.com/october-7th-...ia-conference/
I am not the best when it comes to geographie, but I believe this meeting is near San Diego, CA.

[sdsurfin]

the trials were safety and proof of concept. if their theory works(which is that the number of DSC is responsible for hair length and diameter and injection of cultured DSC can add to that number in balding scalp and can induce hair follicle formation) then I expect they would have great results in dosing trials. they have some science and some results to go further. it may totally fail. it may be a huge success. we can't judge from initial safety trials where the dose is minimized. replicel is based on 10 years of science and research. now shiseido acquired the license and they opened a research facility. they will run their own trial and the research facility is dedicated to hair regeneration. they might tweak the technology.
take a look: http://www.nature.com/jid/journal/v1.../5602058a.html
it has the potential to be a cure but it may also fail. we can only wait .

thanks, your posts are intelligent. And I hope you're correct that it has the potential to do great things. To me it seems a bit strange and disappointing that it was their lead product and now has taken a backseat and will be tested later than for tendinosis.

[hgs1989]

I'm not sure why shiseido got into it, their preliminary results seemed pretty garbage, but shiseido probably has a lot of money to throw around, and if they can keep charging people 5000 or so a pop and you have to refresh then it'll be a great business for them

the trials were safety and proof of concept. if their theory works(which is that the number of DSC is responsible for hair length and diameter and injection of cultured DSC can add to that number in balding scalp and can induce hair follicle formation) then I expect they would have great results in dosing trials. they have some science and some results to go further. it may totally fail. it may be a huge success. we can't judge from initial safety trials where the dose is minimized. replicel is based on 10 years of science and research. now shiseido acquired the license and they opened a research facility. they will run their own trial and the research facility is dedicated to hair regeneration. they might tweak the technology.
take a look: http://www.nature.com/jid/journal/v1.../5602058a.html
it has the potential to be a cure but it may also fail. we can only wait .

[sdsurfin]

Wasn't there some kind of news of them switching up their culturing method to 3D? That could be key...

Replicel has never been about DP cells. They culture DSC cells, which can be cultured in 2D. I bet their treatment works for a little while, but if you have to keep getting re-ups of a 5000 dollar treatment then that is pretty ludicrous for most. I doubt theres any way that even a good exposure to healthy DSC cells will save your hair for good, you still have all this DP and other cells that are prone to balding. If it is not too cost prohibitive it might be great as a bridge until they can inject whole follicle seeds. I'm not sure why shiseido got into it, their preliminary results seemed pretty garbage, but shiseido probably has a lot of money to throw around, and if they can keep charging people 5000 or so a pop and you have to refresh then it'll be a great business for them

[hellouser]

I don't think so.

Replicel has not yet even taken advantage of the new technology to produce iSP DP cells so that means that they will have to culture DP cells so a lot of trichogenicity will be lost. The company Replicel may ultimately produce a treatment that works but the treatment that they are presently studying will need more tweaks before it's a breakthrough. Those new tweaks aren't even discovered yet. And once they're discovered, Replicel will add those new tweaks which means that Replicel will have to start all over with new clinical trials since the new tweaks means it's a new treatment so clinical trials have to start all over.

Wasn't there some kind of news of them switching up their culturing method to 3D? That could be key...

[nameless]

I think RepliCel is gonna do it for us all.

I don't think so.

Replicel has not yet even taken advantage of the new technology to produce iSP DP cells so that means that they will have to culture DP cells so a lot of trichogenicity will be lost. The company Replicel may ultimately produce a treatment that works but the treatment that they are presently studying will need more tweaks before it's a breakthrough. Those new tweaks aren't even discovered yet. And once they're discovered, Replicel will add those new tweaks which means that Replicel will have to start all over with new clinical trials since the new tweaks means it's a new treatment so clinical trials have to start all over.

[efedrez]

I think RepliCel is gonna do it for us all.

Yes, they will!

[FearTheLoss]

I think RepliCel is gonna do it for us all.

[FearTheLoss]

I'd pay 15k to have a treatment that stopped hair loss for a good portion of time, but I'm saying it's useless to worry about price or anything yet if we don't even know it works or if it will come to market.

That being said, I'm thinking they really have something here due to their investments and the quotes I posted a page back from David Hall's interview yesterday.

[hellouser]

Let's not speculate on prices at all when we don't even know the potential of the treatment yet.

Well its safe to say it'll be a similar amount considering the biopsy is done from the back of the head and cultured similarly. The price difference for the tendonosis treatment vs. baldness shouldn't be TOO great. As long as it's under 10k, I'd be satisfied... if it's 5k, I'd be ecstatic.

[FearTheLoss]

3000 for 11% is not cheap and you will feel like robbed for nothing. now if replicel technique really works, the effect on the hair follicles(the one that can be repaired) is not limited by anything except dosing. it will be compoundable. many injections can do wonders (again if it work as said by repairing and also creating new follicles). we can't do many injections at 3000$ a 1000 to 1500 is good. combine that with histogen and we will have good times again. a hair tranplant to fi the hair line and cb for maintenance. gosh can 2017 come any closer

Let's not speculate on prices at all when we don't even know the potential of the treatment yet.

[hellouser]

3000 for 11% is not cheap and you will feel like robbed for nothing. now if replicel technique really works, the effect on the hair follicles(the one that can be repaired) is not limited by anything except dosing. it will be compoundable. many injections can do wonders (again if it work as said by repairing and also creating new follicles). we can't do many injections at 3000$ a 1000 to 1500 is good. combine that with histogen and we will have good times again. a hair tranplant to fi the hair line and cb for maintenance. gosh can 2017 come any closer

Aderans treatment was able to halt further loss. I'd pay that much to do just that. We'll see how things go. I've emailed Tammey George asking about Replicel's initiative to roll out the treatment during Phase 2 trials in Japan in accordance with Japan's new legislation for stem cell treatment.