KÉRATENE Alphactive ® Retard

[Jasari]

Not to rain on anyone parade, but the size of the study they had was like 13 guys. That is way too small to find sides if they do exist for some men. The sides from fin are directly from lowering DHT levels so if this actually lowers DHT levels to a real degree your going to get sides just as if you took weaker doses of finasteride.
Just because their small study did not find sides does not mean there are not any especially given how new it is with small evidence in comparison to propecia.

I've actually ordered tablets; but I have been unable to find how the mechanism differs from that of finasteride i.e. The reason they believe sexual sides will not occur with Keratene.

If they are in fact a lower strength version of Finasteride I wouldn't touch it.

[HARIRI]

I've actually ordered tablets; but I have been unable to find how the mechanism differs from that of finasteride i.e. The reason they believe sexual sides will not occur with Keratene.

If they are in fact a lower strength version of Finasteride I wouldn't touch it.

I got these answers from the Keratene main company (HAIRCLINICS). Please read them.

How does it work?

The molecules works not by inhibiting the production of 5ard enzyme or by regulation the secretion of hormones, but rather by attaching itself by electro-chemical valence to the 5ard enzyme and acting as an insulating factor.
As such, the transfer of atoms of hydrogen to the testosterone molecule happens in a lower ratio.
This leads in turn to an overall reduction of DHT.
As such, the 5ard enzyme production and the testosterone hormone are left untouched.
The only thing which happens in a lesser amount, is the transformation of T into DHT.

Are there differences between KaR and finasteride?

Yes. Kératene alphactive Retarde is completely different than finasteride.
Finasteride is a synthetically engineered molecule, with specific chemical properties.
Kératene alphactive Retarde is an organic compound, not synthetically engineered.
Finasteride has the chemical potential to penetrate the blood brain barrier (see latest FDA updates on fda.gov) and has the bio-chemical potential to influence the pineal gland, the processes that coordinate the production of lutropin, the correlation of the sex-binding hormone globulin, dhea, and many other related factors.
In addition, it may increase on the long run the risk on malign prostate neoplasm with roughly 1.6%.
Because the body perceives its molecule as a foreign chemical, the metabolic processes employed by the body to follows the same pathways as any other medication (see cytokine reduction), whereas in regard to KaR, the body process the substance as an organic element.

[Jcm800]

Since taking this, has anyone noticed any changes for better or worse?

[burtandernie]

Things are never simple with this stuff, but propecia works because it lowers DHT not the way it lowers it such as the 5 ar 2 enzyme. So if this lowers DHT its giving you the same sides probably even if it does it in a different way.
I think lowering DHT to a much lesser extent then propecia could be good though but then of course you might not slow down hair loss as much.

[Jasari]

I got these answers from the Keratene main company (HAIRCLINICS). Please read them.

How does it work?

The molecules works not by inhibiting the production of 5ard enzyme or by regulation the secretion of hormones, but rather by attaching itself by electro-chemical valence to the 5ard enzyme and acting as an insulating factor.
As such, the transfer of atoms of hydrogen to the testosterone molecule happens in a lower ratio.
This leads in turn to an overall reduction of DHT.
As such, the 5ard enzyme production and the testosterone hormone are left untouched.
The only thing which happens in a lesser amount, is the transformation of T into DHT.

Are there differences between KaR and finasteride?

Yes. Kératene alphactive Retarde is completely different than finasteride.
Finasteride is a synthetically engineered molecule, with specific chemical properties.
Kératene alphactive Retarde is an organic compound, not synthetically engineered.
Finasteride has the chemical potential to penetrate the blood brain barrier (see latest FDA updates on fda.gov) and has the bio-chemical potential to influence the pineal gland, the processes that coordinate the production of lutropin, the correlation of the sex-binding hormone globulin, dhea, and many other related factors.
In addition, it may increase on the long run the risk on malign prostate neoplasm with roughly 1.6%.
Because the body perceives its molecule as a foreign chemical, the metabolic processes employed by the body to follows the same pathways as any other medication (see cytokine reduction), whereas in regard to KaR, the body process the substance as an organic element.

Thanks mate - My hair is actually starting to thin in the crown for the first time since I started thinning; I should be able to get a clear idea of whether this works.

[ajays]

Not sure from where you are getting this info. Propecia is a direct 5ard enzyme inhibitor (lookup Wikipedia and other places),which in turn causes drop in DHT. The side effects from propecia (especially libido related) are from 5ard reduction, not specifically dht reduction. If Keratene claims are true i.e. they don't interfere with amount of 5ard, then it's very plausible that there are no major side effects.

In any case, every person has to make their own decision based on what they are comfortable with.

Having said that, I think taking Keratene is much better than taking saw palmetto as atleast there have been couple of clinical studies and HT doctor reviews for KaR compared to saw palmetto. I have decided to go the organic route with KaR for at least 6 months and then decide whether to switch to Fin or maybe Gin

Things are never simple with this stuff, but propecia works because it lowers DHT not the way it lowers it such as the 5 ar 2 enzyme. So if this lowers DHT its giving you the same sides probably even if it does it in a different way.
I think lowering DHT to a much lesser extent then propecia could be good though but then of course you might not slow down hair loss as much.

[burtandernie]

The reason inhibiting the 5 ar 2 enzyme does anything for hair loss is because it lowers your DHT levels. Lowering the DHT levels is why finasteride works. Whether you do it this way or that way if your DHT levels are lowered enough to affect MPB then its all the same.
Of course its always possible through some unknown of which there are plenty of it does work differently somehow.

[ajays]

Agree that fin works because of DHT is lowered. From what i have read so far, the benefits are because DHT is lowered and side effects are because 5ard is lowered.

The reason inhibiting the 5 ar 2 enzyme does anything for hair loss is because it lowers your DHT levels. Lowering the DHT levels is why finasteride works. Whether you do it this way or that way if your DHT levels are lowered enough to affect MPB then its all the same.
Of course its always possible through some unknown of which there are plenty of it does work differently somehow.

[burtandernie]

Agree that fin works because of DHT is lowered. From what i have read so far, the benefits are because DHT is lowered and side effects are because 5ard is lowered.

I would say both the benefits and sides are directly from the DHT being lowered regardless of how its done. DHT is the most potent male hormone so by lowering it your going to have sides whether you do it through their claimed process or through the enzyme that switches T to DHT.
Just my opinion that in theory they should be the same if this product reduced DHT the same amount as fin. I could certainly be wrong with how complex it all is and all the unknowns anything is possible.
I am just interested in this if it turns out to work because I want to keep the hair I have now, but I want to inhibit less DHT then what propecia does. Propecia makes a big change in DHT levels which is certainly not a wise move for some men.

[LongWayHome]

Dear balding friends, I just wanted to inform you that there was a man
back in the 60's that was balding and wrote a song called "while my hair gently weeps" but then George harrison came and no one ever heard of that song.

Now for real:
I'm back on 1 capsule a day, at nights, for a few months to wait and see what happens. Still using the topicals, adding RU premixed 5% from mpb's which probably won't work and minox 15%.
"So, how will you know what's working there and what's not?"

Well...I'm desperate.

"What's your worst fear?"
Being bald, of course...

"What's your favorite color?"
Brown, as my hair.

"What is your favorite food?"
Keratene capsules.

"What's your favorite song?"
While my hair gently weeps.

"You mean 'while my guitar gently weeps' "
No.

I'll keep you updated.

[HARIRI]

I'm back on 1 capsule a day, at nights, for a few months to wait and see what happens. Still using the topicals, adding RU premixed 5% from mpb's which probably won't work and minox 15%.

LongWayHome, I feel for you Bro. Just a brotherly advice, Avoid using 15% minoxidil, you will have terrible sides such as itching, some rapid heart beats and dark eye circles. 15% is too much even if applied once a day. You can try the 10% if you insist. I'm a victim of the 15% Minoxidil before.

Also regarding the mild sexual sides, The RU could lead you to some mild one is it plays with Androgen receptors as well. My advice is that you start with 1% then upgrade to 2% and slowly go up to 5%. Im actually planning to start the 1% RU from Mpb along with my Minoxidil 5% once a day before bed time.

I wish you all the growth Buddy

[thechamp]

Blocking dht

So what's the reason behind blocking dht and weight gain I'm booking a doctors appointment tommrow, going to check that my thyroid is fine and a hormone test any one take fin and worked out why some gain weight?

[LongWayHome]

LongWayHome, I feel for you Bro. Just a brotherly advice, Avoid using 15% minoxidil, you will have terrible sides such as itching, some rapid heart beats and dark eye circles. 15% is too much even if applied once a day. You can try the 10% if you insist. I'm a victim of the 15% Minoxidil before.

Also regarding the mild sexual sides, The RU could lead you to some mild one is it plays with Androgen receptors as well. My advice is that you start with 1% then upgrade to 2% and slowly go up to 5%. Im actually planning to start the 1% RU from Mpb along with my Minoxidil 5% once a day before bed time.

I wish you all the growth Buddy

Actually man, I took minox 15% for like 6 months in the past and then stopped due to price.
Now when I'm not in the military and I work I got the money so I'm going to get back. I used 1ml and nothing bad happened before.
BTW, I talk to someone from Keratene daily, asking question and everything in the email, and when I asked him what is profession is, he told me "One question too much". Why would he tell me that unless they're killing people and making capsules from them? He's probably even watching this now,
so, man, I don't understand the big secret.

[HARIRI]

Actually man, I took minox 15% for like 6 months in the past and then stopped due to price.
Now when I'm not in the military and I work I got the money so I'm going to get back. I used 1ml and nothing bad happened before.
BTW, I talk to someone from Keratene daily, asking question and everything in the email, and when I asked him what is profession is, he told me "One question too much". Why would he tell me that unless they're killing people and making capsules from them? He's probably even watching this now,
so, man, I don't understand the big secret.

Which brand are using for Minoxidil 15%? Could you please tell me?

[LongWayHome]

I'm using Minoxidil................Max.
I think it's the stronget minox for now.