2013

[simba]

God Hariri, I really thought we'd be hearing some amazing news by now!

Did you hear about Rooney! He didn't take Fin after his HT back in 2011 and now he's got these massive bald patches in his crown...so he's gone in for another $30,000 HT! So far he's wasted something like $70,000 to fix his hair and he still looks like he's balding! I mean imagine what you can do with $70,000!

We really need some new breakthroughs ASAP

I think Fin is a banned substance for athletes because it can be used as a masking agent for PEDS.

[Desmond84]

God Hariri, I really thought we'd be hearing some amazing news by now!

Did you hear about Rooney! He didn't take Fin after his HT back in 2011 and now he's got these massive bald patches in his crown...so he's gone in for another $30,000 HT! So far he's wasted something like $70,000 to fix his hair and he still looks like he's balding! I mean imagine what you can do with $70,000!

We really need some new breakthroughs ASAP

[HARIRI]

OK guys,

We are now in September 2013 and the cutting edge forum seems to have taken a dive slowly and bit by bit since March!

When I look back, 2012 was definitely the year of HOPE The positive energy on this forum was just magnificent. Aderans was about to enter Phase 3, while Histogen's Dr Ziering was talking about regrowing hair in the donor zone for new harvestation, and simultaneously Tokyo's Tsuji lab managed to create hair germs that could regrew hairs on skin to its complete natural density (in mice). Cosmo announced it will proceed with approval of CB-03-01 and Histogen's interim results were truly inspiring!

Then came 2013 and by May we all had our eyes set on the Hair Congress So much information was being filtered through the forum and we could smell the cure from miles away! God that was so exciting! Joe from Staten Island had so much to talk about almost every week

But then we took a nose-dive! Allegran's Bimatoprost trial results turned out to be unsatisfactory, Histogen's progress came to a snail's pace, and Aderans went into liquidation in a heartbeat! We've had a rough year with small glimmers of hope...

Replicel managed to get more funding for a 2b trial and Histogen has finally gathered enough resources to do some mini-trials in Taiwan by December. Follica came back from the grave but no date has been announced for their next set of trials.

All in all...we are NOT exactly where we wanted to be BUT there are still players in the game with new ones entering! Incentis pharmaceuticals is one example which has just began its preclinical trials (although we know nothing about their therapy)...

Tsuji lab still has a lot to work out before a human trial, while Lauster/Gerd are looking for a potential investor to begin their work for the first in man trial...Dr Gerd agreed to work with Dr Nigam, but Dr Nigam is NOT ready yet to proceed.

So, I guess that's my summary of the last 2 years for all those infrequent visitors and the newcomers

To a better time when we rock our mohawks like a BOSS

Cheers

- Des

Great Recap Desmond84

What are your thoughts about members going to use the CB-03-01 formula ordered from Iron Dragon or Kane and mixed with Ethanol/PG?

[Desmond84]

OK guys,

We are now in September 2013 and the cutting edge forum seems to have taken a dive slowly and bit by bit since March!

When I look back, 2012 was definitely the year of HOPE The positive energy on this forum was just magnificent. Aderans was about to enter Phase 3, while Histogen's Dr Ziering was talking about regrowing hair in the donor zone for new harvestation, and simultaneously Tokyo's Tsuji lab managed to create hair germs that could regrew hairs on skin to its complete natural density (in mice). Cosmo announced it will proceed with approval of CB-03-01 and Histogen's interim results were truly inspiring!

Then came 2013 and by May we all had our eyes set on the Hair Congress So much information was being filtered through the forum and we could smell the cure from miles away! God that was so exciting! Joe from Staten Island had so much to talk about almost every week

But then we took a nose-dive! Allegran's Bimatoprost trial results turned out to be unsatisfactory, Histogen's progress came to a snail's pace, and Aderans went into liquidation in a heartbeat! We've had a rough year with small glimmers of hope...

Replicel managed to get more funding for a 2b trial and Histogen has finally gathered enough resources to do some mini-trials in Taiwan by December. Follica came back from the grave but no date has been announced for their next set of trials.

All in all...we are NOT exactly where we wanted to be BUT there are still players in the game with new ones entering! Incentis pharmaceuticals is one example which has just began its preclinical trials (although we know nothing about their therapy)...

Tsuji lab still has a lot to work out before a human trial, while Lauster/Gerd are looking for a potential investor to begin their work for the first in man trial...Dr Gerd agreed to work with Dr Nigam, but Dr Nigam is NOT ready yet to proceed.

So, I guess that's my summary of the last 2 years for all those infrequent visitors and the newcomers

To a better time when we rock our mohawks like a BOSS

Cheers

- Des

[JJJJrS]

I don't think there's any point worrying about things like release dates or cost when we don't even know if these treatments are effective. At these point, almost all the numbers and figures that have been released have been underwhelming.

[young]

What I don't understand is why the FDA is having such a big part in this. There are far more advanced and efficient countries than the US...

And what about the ones that arent? Surely, all these brilliant scientists could have labs in an obscure country where they can try out this stuff without all the bullshit.

Now there's a thought... Lol. Some shady island... Go there to join the Hair Club. Just like Fight Club, except you get a NW0 instead of an ass whooping. 50k.

No problemo!!!!

Just please someone find the solution so we can make you the richest person alive! I am not demanding anything like I am entitled to anything... But just think about it. Richest person alive. Richest person ever.
Go on!!! You can do it!!

[StinkySmurf]

yeah right

it depends on what you want to call a libertarian I guess. If your definition is someone who wants a less cumbersome FDA, then I would say the chances are better than 50/50 that a libertarian is elected to the white house in 2016.

I think the rules even relaxed under Obama for life threatening conditions so it's not a shocker

[rdawg]

FDA rules while understandable are just a little too slow.

IMO should be a two phase(maybe 2.5) system, 1st phase is safety and efficacy for one year, second phase 1.5 years tested similar to a phase III.

then limited release for a year for safety purposes(say in select big markets), then full release after that.

right now it's alot of phase I/II, then IIb, the IIb again! then III and bam 5 years go by with barely anything done!!!

[Thinning87]

libertarians are gaining ground very quickly in the USA right now. if they win control of the white house in 2016, it could mean more rapid changes to the FDA.

yeah right

[StinkySmurf]

The THREE phase trial system is the result of a 20th century methodology, which although is very sound and robust has considerably slowed down release of 1000's new therapies to the market, due to the cost of conducting such trials!

libertarians are gaining ground very quickly in the USA right now. if they win control of the white house in 2016, it could mean more rapid changes to the FDA.

[DepressedByHairLoss]

We need a maverick Scandinavian country to come up with a new way to test for Drug Safety and abolish the pain staking task of conducting a 10 year pre-clinical and then clinical Phase I, II, III trials!

Hopefully, with Dr Lauster's microchip technology pre-clinical studies can be conducted at a much more rapid pace!

The THREE phase trial system is the result of a 20th century methodology, which although is very sound and robust has considerably slowed down release of 1000's new therapies to the market, due to the cost of conducting such trials!

The rate of NEW drug molecules being approved has declined by over 70% since the early 90's due to this very problem many Pharmaceutical companies are facing.

I personally don't blame Gail's frustration with sourcing funds to continue with her trials....

Maybe Dr. Nigam's new technologies for hair regrowth can be released in India without these retardedly extensive clinical trials. I would travel to India in a second if there was proof that my hair could be regrown without surgery.

[drnigams]

DESMOND,
Gerd and his company partners are into similar ambitious project..to create mini body organ systems with minimum cells and tissue with blood vessels in lab ,in microchip with bioreactors...i had a look at it when i was at thier lab..

They are right now developing blood vessels in vitro in lab..rest they
have..and than it is upto fda to recognise this is safe model..for testing clearance..for humans or atleast avoid animal testing...

Once we can grow organs in a lab...Pharma labs should be allowed to simply have Kidney, Liver, Heart, Lung models that they get to test their products on! If all is good, there is no need for Phase I and II trials!

A Pharma company should conduct a small 6 month dose range finding study followed by a 12 month large scale Phase 3 study!

All in all...human trials should NOT exceed 2 years

[Desmond84]

Once we can grow organs in a lab...Pharma labs should be allowed to simply have Kidney, Liver, Heart, Lung models that they get to test their products on! If all is good, there is no need for Phase I and II trials!

A Pharma company should conduct a small 6 month dose range finding study followed by a 12 month large scale Phase 3 study!

All in all...human trials should NOT exceed 2 years

[Desmond84]

We need a maverick Scandinavian country to come up with a new way to test for Drug Safety and abolish the pain staking task of conducting a 10 year pre-clinical and then clinical Phase I, II, III trials!

Hopefully, with Dr Lauster's microchip technology pre-clinical studies can be conducted at a much more rapid pace!

The THREE phase trial system is the result of a 20th century methodology, which although is very sound and robust has considerably slowed down release of 1000's new therapies to the market, due to the cost of conducting such trials!

The rate of NEW drug molecules being approved has declined by over 70% since the early 90's due to this very problem many Pharmaceutical companies are facing.

I personally don't blame Gail's frustration with sourcing funds to continue with her trials....

[UK_]

Big pharma wont listen, it's taken people close to a century to convince them that marijuana has medicinal properties.