-
-
This is what's winding me up with your posts Ironman - why're you doing this whole thing with making people 'tell you stuff'? You wanna make some comment just make it already! But just to stop this stupidness - he says it's the combination of injuring and a compound. But why are you bringing this up? That was Follica's approach - Follica's dead! Are you saying that Histogen needs to injure the scalp and then apply HSC?Comment
-
Thanks - I just wanted to hear this from another user. Okay, now back to my questions:
1) Histogen is BASED ON everything what Dr. Cotsarelis is talking about in this (posted) video. That's simply a fact, and Histogen mention this in their papers, presentations etc.Can someone do me a favor, please?
starting at 02:00>>what exactly is Dr. Cotsarelis saying in this video?
He is talking about a "combination". Combination of WHAT exactly created the hairs on the mouse's back - and what's the reason why you shouldn't try this at home?
And finally, 1) what has this to do with Histogen, 2) Histogen's presentation at the ISHRS meeting and finally, 3) Dr. Cole's report? I will tell you this thereafter...
1a) Histogen just produces the mentioned "compound" (HSC=hair stimulating complex) in their labs, which can improve such results as Dr. Cotsarelis got them in his mouse-study with a similar COMPOUND (Wnt's based etc) - in addition to WOUNDING (=full thickness wound) of the skin.
2/3) This threads TOPIC:
Dr. Cole reported in a video, that she, Dr. Gail Naughton, mentioned at the meeting something like "HSC can even grow hair in 'scar tissue'!" and Dr. Cole said something like (not 1:1 transcript!) "If this stuff works so great even in scar tissue - why there is the need to show us pics with lots of hairs in the BEFORE photos??" - or something - right?
Anyway, I think this has been a misunderstanding at the meeting, and Dr. Naughton meant actually "This stuff could produce/helped growth of hairs even in WOUNDS" - and thought about their own mouse-studies and Dr. Cotsarelis findings. Period. There is simply a difference between freshly created full thickness WOUNDS and old SCAR TISSUE.
And now the easy to understand point:
Without FULL THICKNESS WOUNDING, und just injecting such stuff into the skin, this works just like injection of water or cat piss into the skin - USELESS for creating brand new mini-organs like hair follicles or "rejuvenation" of existing hair follicle structures, simply because this "window", as mentioned by Dr. Cotsarelis in his study, doesn't happen/exist with just injectioning such stuff. This is well known among research-scientists. This "window" just happens in the event of "full thickness wounding" and works better or not at all "species-related" - among lots of other different conditions. In simple words - Histogen's HSC, is just based on "hot air" and that's THE reason why they can't show you any LEGIT photos since so many years.Comment
-
Ok so all this fuzz for this post above? Your speculations and deductions don't affect those of us who have decided to remain cautiously optimistic. We'll see what happens with Histogen, few of us expected the ultimate cure, most of us were hoping for some better version of Rogaine to hang on to our hair for a few years, hopefully with less Finasteride.Comment
-
not coming, they'll give us more by around march/april final IIa results.Originally posted by koolxComment
-
Sure. Histogen says HSC can even grow brand new hairs in scar tissue...
...so why not on the temples/hairline, where there is no scar tissue?
I mean, perhaps it doesn't work for you, perhaps not for me and perhaps for nobody, but it has at least the potential to work for somebody or something - like Propecia or TRX-2.Comment
-
In their last trail they stated that it for sure works on the temples.Sure. Histogen says HSC can even grow brand new hairs in scar tissue...
...so why not on the temples/hairline, where there is no scar tissue?
I mean, perhaps it doesn't work for you, perhaps not for me and perhaps for nobody, but it has at least the potential to work for somebody or something - like Propecia or TRX-2.Comment
-
They also provided photographs as well, there was a HUGE response on the hairlosshelp forums praising Histogen for their achievements. I don't remember the density of the temple regrowth... this was also a while back so they could have only made greater progress since. Hard to turn down Histogen at that point.Comment
-
There was obvious photographic evidence that it worked in the temple region.
Also, dr. ziering is a very well respected doctor who isn't going to ruin his reputation by lying to the hair loss community. He has nothing to gain by lying. With that being said, we just need to see what histogen releases this april and I think then we will know for sure which way they are headed.Comment
Tweet
Comment