Histogen show "cosmetic" results oct 2012 update

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  • yeahyeahyeah
    Senior Member
    • Nov 2011
    • 1776

    Originally posted by 534623
    So, who plays the dice?
    I think guys like Sir Evans play the dice ...
    Whatever.

    You always find an answer to everything.

    You do know the scientists at histogen aren't exactly amatures.

    Comment

    • Dan26
      Senior Member
      • Jul 2012
      • 1270

      Originally posted by 534623
      So, you're talking about stem cell cures/treatments for (complex) organs like hair follicles - right?
      Histogen is talking about embryonic stem cells and Replicel tries to cure hair loss with dermal sheath cup cells (DSCC) - right?

      Nope – this is not what British geneticist and stem cell researcher Sir Martin J. Evans predicted in an interview recently.

      Or do you think that, instead of Sir Evans, the people behind Histogen and Replicel should get

      1) The Nobel Prize

      2) and the Queen should confer a knighthood on them??

      In other words, you trust them more than in so-called "Superstars of Science" ??
      I didn't even read the article, but ain't it more about $$$ and business then science???

      Comment

      • clarence
        Senior Member
        • Sep 2012
        • 278

        Originally posted by hairysituation
        Wishful thinking, my friend. Histogen could work with maintaning, but they are years away. Aderans won´t work, reallstically. I will not start a Gho debate here, but let´s just say I don´t believe it for a second.

        However, OC seems promising, some users on ************ have reported good effects. But the safety profile is not yet established (topically), and there are very few people who have tried it.

        I say the best approach today is a transplanted juvenile hairline with a hairpiece behind. I will use this approach, and get away from these forums. Of course it´s given that my transplant is sucessful, which is not certain at all.

        It´s not a perfect solution, but beggars can´t be choosers.
        Why do so many want to have a juvenile hairline? To look like a caveman? To make the nose look bigger? Or just to look weird? Why so hirsute? How would a mature hair line alone inhibit you from leaving these forums?

        Comment

        • 25 going on 65
          Senior Member
          • Sep 2010
          • 1476

          Originally posted by yeahyeahyeah
          Whatever.

          You always find an answer to everything.

          You do know the scientists at histogen aren't exactly amatures.
          He is just trying to find ways to make Gho seem viable.

          Comment

          • Pate
            Senior Member
            • Sep 2011
            • 417

            Originally posted by 534623
            So, who plays the dice?
            I think guys like Sir Evans play the dice ...
            This has absolutely nothing to do with hair loss but I have a degree in astrophysics so I can't let this BS go unchallenged.

            It wasn't chaos theory that Einstein was referring to by "God does not play dice" but the probabilistic interpretation of quantum mechanics.

            We now know that Einstein was wrong and the probabilistic interpretation has been proven since the 1960s.

            Chaos is a non-quantum theory. It's a different thing entirely.

            So yeahyeahyeah is correct in both fact and in what he was trying to say - scientists do get it wrong, even the greatest of them all.

            Also, Sir Martin's comments do not apply to Histogen for two reasons:

            1) He's talking about full-on stem cell therapy, not the use of growth factors
            2) Histogen have already proven they can turn vellus hairs to terminal

            Comment

            • Whair
              Junior Member
              • Mar 2012
              • 7

              was Sir Martin knighted by the same person that knighted Jimmy Savile . Did Bill Gates once say the internet wouldn't catch on......

              Comment

              • CAlex
                Senior Member
                • Feb 2011
                • 112

                I hate to point this out but Histogen, Replicel and Aderans dont need any of the current hair loss sufferers/forum people like us to use their products to make gazillions of dollars when they hit the market.

                Take histogen for example. if their 85% success rate stays that high and all they end up being able to do is increase density by 20% or hell even no density increases at all, a long as they are able to strengthen weakening hairs and halt further hairloss in the injection site for the 2 year period which I believe they have proven up to this point.

                All they need to do is come to market in 2016 or whenever and they will be such a good no side effect preventative measure that they will be as good as a cure as long as the young men and women get follow up treatments every 2-3 years until a true treatment is created.

                example.

                its 2016 and a 17 teen year old guy begins to fear he might be losing some density he could go to his doctor..have some testing done (density testing in temple and then retest every 6 months for comparison, doc looks for weakening hairs etc) if he looks to be at the very very early stages of hair loss he could just get some histogen injections and repeat every 3 years. problem solved.

                over the next 15 years he spends 10-20k on injections and never goes through what we have.

                I think that is why ironman and some others on here are so hate on at histogen because it doesnt suit their needs of addressing extreme regrowth.

                I think if you objectively and not selfishly look at histogen, they definitely are making great progress at saving people in currently ages 10 -15 yrs old from having to go through what people on here have.

                thats just my thoughts on the subject. I hope histogen and the likes can help everyone reading this one day. Hopefully all those reading this can take some comfort knowing others wont have it as bad as we did, fingers crossed.

                Comment

                • clarence
                  Senior Member
                  • Sep 2012
                  • 278

                  Originally posted by CAlex
                  Hopefully all those reading this can take some comfort knowing others wont have it as bad as we did, fingers crossed.
                  not gonna help me get laid more often, on the contrary, yeah and phuck those brats

                  Comment

                  • 534623
                    Senior Member
                    • Oct 2011
                    • 1854

                    Originally posted by Pate

                    Histogen have already proven they can turn vellus hairs to terminal
                    No. The only fact they have proven so far is this well-known fact:


                    Read more ...

                    btw - in the left pic, where can you see a "vellus hair" ?
                    Typical vellus hairs are NOT pigmented!!

                    Comment

                    • Kiwi
                      Senior Member
                      • Mar 2011
                      • 1087

                      Originally posted by clarence
                      not gonna help me get laid more often, on the contrary, yeah and phuck those brats
                      Yeah phuck em!

                      Comment

                      • yeahyeahyeah
                        Senior Member
                        • Nov 2011
                        • 1776

                        Originally posted by 25 going on 65
                        He is just trying to find ways to make Gho seem viable.
                        The irony is , I felt a glimmer of hope until these cowboys started posting downplaying the treatment.

                        I honestly think that histogen had good intentions with their press release, in other words they are saying:

                        'look guys - we are working on something, so dont lose hope'

                        Irrespective on if they are right or wrong, negative assholes like iron man and 2020 have brought the whole forum down. In the process getting balding people in a depressed state. Sometimes guys 'ignorance is bliss'

                        I guess it's true what they say 'misery loves company'

                        Comment

                        • yeahyeahyeah
                          Senior Member
                          • Nov 2011
                          • 1776

                          Originally posted by CAlex
                          I hate to point this out but Histogen, Replicel and Aderans dont need any of the current hair loss sufferers/forum people like us to use their products to make gazillions of dollars when they hit the market.

                          Take histogen for example. if their 85% success rate stays that high and all they end up being able to do is increase density by 20% or hell even no density increases at all, a long as they are able to strengthen weakening hairs and halt further hairloss in the injection site for the 2 year period which I believe they have proven up to this point.

                          All they need to do is come to market in 2016 or whenever and they will be such a good no side effect preventative measure that they will be as good as a cure as long as the young men and women get follow up treatments every 2-3 years until a true treatment is created.

                          example.

                          its 2016 and a 17 teen year old guy begins to fear he might be losing some density he could go to his doctor..have some testing done (density testing in temple and then retest every 6 months for comparison, doc looks for weakening hairs etc) if he looks to be at the very very early stages of hair loss he could just get some histogen injections and repeat every 3 years. problem solved.

                          over the next 15 years he spends 10-20k on injections and never goes through what we have.

                          I think that is why ironman and some others on here are so hate on at histogen because it doesnt suit their needs of addressing extreme regrowth.

                          I think if you objectively and not selfishly look at histogen, they definitely are making great progress at saving people in currently ages 10 -15 yrs old from having to go through what people on here have.

                          thats just my thoughts on the subject. I hope histogen and the likes can help everyone reading this one day. Hopefully all those reading this can take some comfort knowing others wont have it as bad as we did, fingers crossed.
                          Sure.

                          But you seem to forget that with other companies working on this, whoever releases first will make the most amount of money. As they will develop a monopoly.

                          And for anyone that releases later on they will also be under more pressure to upstage the guy who releases first in order to take the market share away from them, which means more time will be spent investing during the development phase. Unless of course it is a different treatment, by that addresses different norwood scales.

                          Finally, a company like histogen is a 'bio startup', where your argument falls flat is simply down to the fact that they don't have unlimited funds during the clinical phases. Eventually they will need to make a return of investment to stay afloat and keep private investors happy. Who I don't think will be happy if the product stays in vaporware for 20 more years. If they ignore this, potential investors will lose confidence in histogen and its treatment, causing them to lose funding.

                          Comment

                          • Smiley
                            Member
                            • Oct 2011
                            • 65

                            Originally posted by yeahyeahyeah
                            Sure.

                            But you seem to forget that with other companies working on this, whoever releases first will make the most amount of money. As they will develop a monopoly.
                            .
                            Yes your right in a sense. That the first one to release a viable treatment will make a lot of money. But the first one to give us a 'Cure', or turn a nw7 to a nw1 will make the most money no matter when they release.

                            Comment

                            • yeahyeahyeah
                              Senior Member
                              • Nov 2011
                              • 1776

                              Originally posted by Smiley
                              Yes your right in a sense. That the first one to release a viable treatment will make a lot of money. But the first one to give us a 'Cure', or turn a nw7 to a nw1 will make the most money no matter when they release.
                              This is the BIG point:

                              Finally, a company like histogen is a 'bio startup', where your argument falls flat is simply down to the fact that they don't have unlimited funds during the clinical phases. Eventually they will need to make a return of investment to stay afloat and keep private investors happy. Who I don't think will be happy if the product stays in vaporware for 20 more years. If they ignore this, potential investors will lose confidence in histogen and its treatment, causing them to lose funding.
                              And you boys need to be realistic, there WILL be no cure. Just an improved treatment using stemcells, overtime as the treatment is perfected than a cure will be created.

                              Stemcell research is in its infancy.

                              Comment

                              • The Alchemist
                                Senior Member
                                • Mar 2011
                                • 261

                                A "cure" would be great. But, honestly, i would be happy if they came out with something that could arrest the balding process and provide some mild regrowth - maybe upgrade you a norwood level. That, plus what we have available with hair transplant technology and Gho's HST would be enough to save most from having to suffer the fate of the everlasting horsehoe.

                                For guys NW4 or lower, that would practically be a cure. Use the treatment to get to a NW3 and stop further loss. Then you could go to Rahal/Feller/H&W or whomever and feel perfectly ok saying lower that mother-f'er and make it straight and dense.

                                I don't think this type of approach is out of reach, and could be available within next 5 years from Histogen. Maybe Aderans is having luck - they certainly are putting a lot of money into it and that they're moving to phase III is very, very encouraging.

                                Comment

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