If it were PGD2.....

[neversaynever]

Nice interview with Dr Cots....

http://www.aad.org/dermatology-world/monthly-archives/2012/june/can-blocking-pgd2-prevent-androgenetic-alopecia-

[gutted]

right, so I'm guessing 100% of people didn't know that actual follicle size changes from cycle to cycle... that makes Histogen and all other stimulants useless

http://www.hairdoc.com/book/Chapter_...ss_answers.pdf

dude you are misinterpreting what they are saying.

They miean minuturisation as the follcile starts to stop production and begins to "regress" or "minuturise".

When its time to regenerate during early anagen the hair follcile begins to grow back to normal size but in mpb individuals the size of the follicle develops/regenerates partially minuturised and not to full size.

histogen will last a decent length of time if inflamation is addressed. If not it will last probably 2/3 hair cycles, until it becomes dormant again.

[gutted]

exactly why the **** didn't Spencer ask this question during their 40 minute interview:

what makes you think a follicle will start a second cycle after growth factors for the first cycle stop working?

I changed my position from optimistic to we're all ****ed...

i think i know what you are trying to say with histogen.

Your saying that because histogen supplied the initial growth factors for the hairs to regrow/regenerate then we would need to continuously supply the hairs with those histogen growth factors for it to regenerate again?

[2020]

Your saying that because histogen supplied the initial growth factors for the hairs to regrow/regenerate then we would need to continuously supply the hairs with those histogen growth factors for it to regenerate again?

yes, because your body provides those growth factors naturally before hair enters anagen phase. For bald people that doesn't happen and that's why those hairs stay permanently in telogen phase.

Histogen CAN provide those growth factors to artificially simulate another anagen phase for you, but after that phase is over your body couldn't reproduce those growth factors again for another phase so you would need Histogen growth factors again....

Histogen == +1 extra hair cycle which actually sucks really bad I'm not sure if they know it themselves

[2020]

When its time to regenerate during early anagen the hair follcile begins to grow back to normal size but in mpb individuals the size of the follicle develops/regenerates partially minuturised and not to full size.

right so something went permanently wrong when your body can't reproduce follicles again at normal size....

histogen will last a decent length of time if inflamation is addressed. If not it will last probably 2/3 hair cycles, until it becomes dormant again.

now where did you get that number? Are you saying that Histogen's growth will wear off due to DHT/PGD2 or because they only last one phase?

[gutted]

right so something went permanently wrong when your body can't reproduce follicles again at normal size....



now where did you get that number? Are you saying that Histogen's growth will wear off due to DHT/PGD2 or because they only last one phase?

im confident histogen will last quite some time and not one cycle. It will stimulate the body to cycle dormant hairs again. Only time will tell though.

[ovoxo]

Histogen CAN provide those growth factors to artificially simulate another anagen phase for you, but after that phase is over your body couldn't reproduce those growth factors again for another phase so you would need Histogen growth factors again....

so you would need histogen injection like once a year or so?

[2020]

im confident histogen will last quite some time and not one cycle. It will stimulate the body to cycle dormant hairs again. Only time will tell though.

I'm not confident about that at all.... are you saying that Histogen hairs will last as long as it takes for DHT to shrink it or will it at last as long as when Histogen growth factors wear off?

[2020]

so you would need histogen injection like once a year or so?

one anagen phase so 2-3 years. Depending on how fast you shed, that fallen hair won't grow back...

[ovoxo]

and is it really a problem that you would get histogen treatment every 2-3 years?

[25 going on 65]

If I had to get re-injected every 24-36 months I would still do it.

Still a hell of a lot more convenient than twice-daily minox. Or getting a chunk of scalp sliced out the back of my head.

[gutted]

I'm not confident about that at all.... are you saying that Histogen hairs will last as long as it takes for DHT to shrink it or will it at last as long as when Histogen growth factors wear off?

dude, we dont know the details, all you can do is speculate, i personally think once the hair starts growing through histogens injection, the body will takeover and cycle the hairs normally.

If your unlucky and your adrogen levels havent balanced out through age, those hairs will minuturise again. So yes "dht" levels are still a factor with histogen.

[2020]

and is it really a problem that you would get histogen treatment every 2-3 years?

.... your MPB is still progressing though... more and more follicles will fail to enter anagen phase and you will need more and more injections and then you will become a NW6 and you won't be able to keep up with the injections it's going to be ridiculous.

yes this is a HUGE problem

[gutted]

one anagen phase so 2-3 years. Depending on how fast you shed, that fallen hair won't grow back...

dude you cant say that, when hairs are proliferating i.e growing, growth factors are continually being secreted every single day, theres no reason to think histogen will wear off unless you have not addressed your underlying problems.

Histogen probably works through stimulating wound regeneration, is it a coicidence that acell is used for wound regeneration too and grows at least some hair in some individuals...

[2020]

dude, we dont know the details, all you can do is speculate, i personally think once the hair starts growing through histogens injection, the body will takeover and cycle the hairs normally.

If your unlucky and your adrogen levels havent balanced out through age, those hairs will minuturise again. So yes "dht" levels are still a factor with histogen.

ok let's say you get a 1000 histogen injections and now you're a thick NW1. Then you get castrated. Will Histogen's hair fall off eventually? Yes or No?
My guess is that it will since they should only last one phase due to your follicles not being able to control cycling....