Aderans

[534623]

"here later you can see the increase in hair follicles and obviously... countable... if you think of the balding circle... this is the edge of the balding circle so there are more hair follicles here whereas here towards the center fewer hair follicles... and you can see here the ability of these cells to turn on hair follicles that had been miniaturized and had been over time reduced, over and over, the length and duration of their anagen cycle"

Thanks StinkySmurf.
Could you please make a short transcript of the "skin sample thingy" I mentioned in my previous post? I think this part is pretty interesting ...

I'm talking about this thingy.

[StinkySmurf]

Do you guys understand what I mean/predict with that?
Perhaps this is just a paranoia - but I doubt I have paranoia...

They filed the patent below for the pre-screen, but I don't think the scenario is the same as the fox test. Yes, they will try to sell you a HT if you can't get HM, and honestly, at thats the point where they probably should, but in my mind the pre-screen is what prevented people from moving forward in the past because your need 10 happy customers for every 1 unhappy customer so think of how hard it will be to market something that only works half the time. Your customers are going to get pretty pissed when they give a 1cm biopsy, and it doesn't work. You can give them a refund when it doesn't work, but then that effects your profit model, and it still doesn't fix the problem that your negative responses outweigh the positive ones.

http://www.aderansresearch.com/pdfs/US_Patent_7985537.pdf

[534623]

Your customers are going to get pretty pissed when they give a 1cm² biopsy, and it doesn't work. You can give them a refund when it doesn't work, but then that effects your profit model, and it still doesn't fix the problem that your negative responses outweigh the positive ones.

Same thoughts here. And guess what:
They will get this on the market - for sure. And now guess how much just this TEST will cost a patient ... they will ALWAYS make a profit. But surely not always each and every patient.

[Desmond84]

Desmond, I have to ask again..

"Replicel, Aderans, Follica & Intercytex have all folded!"
"It's all over I think! Baldness will not be cured in this decade"
Based upon WHAT exactly Desmond?

Artista, I'm so sorry for being so negative last night! Finding out about Aderans giving up their DP protocol really got me down! It was confirmed both by Boldy & IronMan and Dr. Nigam & Lauster!!!!

If their DP model was coming out, we would get to keep our remaining hair forever! so you can imagine my frustration when you find out they cheaped out just so they can make more money quicker

So here's what I mean:
- Replicel: Achieved 6% regrowth in most trial subjects. Now although the regrowth rate was low (Minoxidil: 10% & Fin: 15-20%), Replicel has the potential to immunise your follicles against DHT! Now, here's the problems:
a) Replicel has minimal funding and after releasing their recent results, their shares dropped in price by 300%!
b) Assuming they will try and improve their formula, they will try to conduct another Phase 2 results. This will push their product launch date back to at least 2017-2018.

- Aderans: Ji gami will cost at least $10,000-15,000. And that's just being optimistic. Now, I was happy to pay that knowing I will get to keep my hair for a very long time to come since my DP cells will be immune to DHT! But what they're doing now is different. They seem to be rejuvenating your hairs so that they grow again. They will then be like you should jump on Finasteride to keep this hair or it will miniaturise again! In such a case, would you pay them that kind of money?

- Intercytex: this company which was really well funded by UK government reached great heights and produced considerable amount of hair! But in 2008, recession hit Europe and their funding got pulled! So they shut down. Then, Aderans bought this company in order to gain their patents and research. But instead of using them, Aderans simply kept it on their shelves to prevent future competition!

- Follica: a company that had probably the most proactive scientist involved in hair loss (Dr Costralis) associated with it. Unfortunately, Follica finished their Phase 2 results in 2010 and never went into Phase 3. Dr Costralis then moved on with his PGD2 adventures and no new information about Follica has been released ever since!

Now, all we're left with are:
- Hair transplants
- Histogen

I wanna be psyched up about Tsuji Lab and Dr. Lauster. But their technique is a mammoth of a task compared to Replicel and Aderans. So, based on what we've gone through with Aderans/Relicel,I really don't know if they'll be successful in bringing out a solution before most of the guys on this forum turn 45-50!

I had so much hope for Aderans.....so much. Unfortunately, when a company releases very limited information over 11 years, you find yourself searching in the dark for a power switch that was never there!

I really want to be optimistic but I don't know how! I've been down this whole weekend!

[534623]

I had so much hope for Aderans.....so much.

Not just you ...

But hey hey ...

- Aderans: J
They seem to be rejuvenating your hairs so that they grow again. They will then be like you should jump on Finasteride to keep this hair or it will miniaturise again!

Even so, and IF this works what you describe, this would be superb for lots of guys out there. Maybe there will be something similar to Propecia in the meanwhile, but not that "risky" or problematic for patients. So the point is - HOW MUCH of your still existing hair will they indeed be able to "rejuvenate".

If it works, but just for an uncertain time or if you still need additional meds OR consecutive procedures etc, then it will be rather a question about the involved costs all in all over a period of time. In this case, I would rather go for transplants.

[Jairus]

More great news...

This is a load of absolute bollox - seems they have let the dollar signs compromise the release of a genuine product.

What the f**k is the point in paying 10k for a product that will just rejuvinate and not immunize? The point of this was to do away with Fin.

Im not going near Fin and was really looking forward to Aderans.

Looks likw 4+ HT's for me now.

[Desmond84]

If it works, but just for an uncertain time or if you still need additional meds etc, then it will be rather a question about the involved costs all in all over a period of time. In this case, I would rather go for transplants.

Exactly right!

What's the point of getting a 1cm2 bald patch just to find out there's 40% chance there's nothing they can do for you! On top of it, they will charge $500-$600 for this genetic test!

Then if you are a responder, you have to pay them $15000 just to rejuvenate hairs that only miniturised over the last 18 months!

Furthermore, you will still have to take Fin untill CB comes out! which wont be at least till 2017-2018

So, all in all is $15000 worth what they can achieve? that's definitely something that we should discuss!

[534623]

So, all in all is $15000 worth what they can achieve? that's definitely something that we should discuss!

No, we shouldn't discuss this - otherwise the kids in this forum will create threads like "F***Off Desmond84 ..." or something ...

[StinkySmurf]

I was told by a person who I believed the results were very good so I'd like to know what exactly are they doing if they aren't doing DP. Anyone have a guess?

[john2399]

15 grand? who the f would spend that shitload of money on this crappy treatment? Aderans is done.

[UK Boy]

No, we shouldn't discuss this - otherwise the kids in this forum will create threads like "F***Off Desmond84 ..." or something ...

To be honest I don't think they would, people tend to like Desmond on this forum. He has always been a postitive contributor to the forum. You contribute A LOT of stuff Ironman but you do it in a horrible, patronising way and you just have an answer for everything, you may be a very intelligent guy but a little tact and modesty goes a long way rather than just saying "I'm right and you're all idiots, this is why...."

I haven't been following this properly, I tend to just drift over your posts that go on and on, obviously Desmond has bothered to look into what you've said and has found it to be true. I also haven't seen where Dr's Lauster and Nigam back it up but again I'll trust Desmond on that one. Although when did Nigam become an authority on this stuff?! Last I heard everyone was saying he was a big fraud! And is Lauster posting on the forum now or something then? I thought we tend to never here anything from him anywhere.

Anywayz I agree that if all Aderans can do is rejunvinate recently miniturised follicles for an unknown period of time then they are useless. Their tests have all been on the crown as well haven't they? so there's a good chance that they'll do nothing on the frontal area at all, so def not worth the cost of losing a patch of scalp (I was never keen on this anyway and always prefered Histogen for this reason) or the cost in money. I wouldn't pay £1,000 for it let alone £15,000 hopefully the general consencious will be the same and they'll lose out big in the long run. Just so annoying that so much time and money was wasted on this.

[Desmond84]

Iron_Man I really hope you're right about Aderans is still using DP!

As long as DP cells are used and it actually aggregates around the hair follicle structure, immunity to DHT may be possible!

We just have to wait till June and hear their official media release! God I'm so tired of waiting...

[UK Boy]

I was told by a person who I believed the results were very good so I'd like to know what exactly are they doing if they aren't doing DP. Anyone have a guess?

Can you say who told you that? How would they know what the results were like? Were they a trial patient? or involved in Aderans? or were they just someone who saw a presentation?

[Desmond84]

To be honest I don't think they would, people tend to like Desmond on this forum. He has always been a postitive contributor to the forum. You contribute A LOT of stuff Ironman but you do it in a horrible, patronising way and you just have an answer for everything, you may be a very intelligent guy but a little tact and modesty goes a long way rather than just saying "I'm right and you're all idiots, this is why...."

I haven't been following this properly, I tend to just drift over your posts that go on and on, obviously Desmond has bothered to look into what you've said and has found it to be true. I also haven't seen where Dr's Lauster and Nigam back it up but again I'll trust Desmond on that one. Although when did Nigam become an authority on this stuff?! Last I heard everyone was saying he was a big fraud! And is Lauster posting on the forum now or something then? I thought we tend to never here anything from him anywhere.

Anywayz I agree that if all Aderans can do is rejunvinate recently miniturised follicles for an unknown period of time then they are useless. Their tests have all been on the crown as well haven't they? so there's a good chance that they'll do nothing on the frontal area at all, so def not worth the cost of losing a patch of scalp (I was never keen on this anyway and always prefered Histogen for this reason) or the cost in money. I wouldn't pay £1,000 for it let alone £15,000 hopefully the general consencious will be the same and they'll lose out big in the long run. Just so annoying that so much time and money was wasted on this.

Thx Brother

I try to be positive! But there seems to be some truth behind what Iron_Man is saying! I don't know how I missed it! When you listen carefully, what they're using is a soup of dermal and epidermal cells without any indication as to what these cells might be!

Washenik also specifically points out that there has been definitely no new hair follicles forming!

With regards to Dr Lauster, that's something Dr. Nigam claimed he told him regarding Aderans! So who knows if he's making it up or not!

I'm not a big fan of Nigam either btw

[UK Boy]

Iron_Man I really hope you're right about Aderans is still using DP!

As long as DP cells are used and it actually aggregates around the hair follicle structure, immunity to DHT may be possible!

We just have to wait till June and hear their official media release! God I'm so tired of waiting...

!!!????? I've been on here too much today - too many ups and downs it's like a roller coaster! Desmond (Mr.Optimistic) you were on this major downer - I thought you had definite proof of what you were saying and it was all over, now just because of what Ironman has said you've done a full reversal, taken it back and gone back to "We'll have to wait and see what they say the..." WTF!?