It's not a cure in any case, it will probably require daily applications. Plus the patented MPB Prostaglandin treatment is a mix of growth stimulating 'glandins and PGD2 inhibitor(s) and not just the latter. I'm assuming it could be marketed as a daily use shampoo. We also know that androgenic receptors can mutate when inhibited too much, who can tell that won't happen with the PGD2 receptor as well?
I think the most realistic expectation is, as usual, a mix of the best and the worst: a pretty good treatment which requires daily application and can lose effectiveness after a few years, being somewhat expensive as well. Something to look forward too? Definitely, but "the cure"? I seriously doubt it.
Then again, i would be incredibly glad to be proven wrong.
OC000459? (Yes that's its name)
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You keep saying that it has nothing to do with the immune system, you do realize that PGD2 is intimately connected with the immune system don't you? PGD2 is produced by mast cells (involved in the immune system), it then recruits helper t cells, eosinophils and basophils (all white blood cells & part of the immune system). So saying PGD2 is the problem and at the same time saying it has nothing to do with the immune system makes you sound extremely ignorant and uninformed. PGD2 may very well be a critical component to solving hair loss, but to say that's it we have found it, NW7---> NW1 is very irresponsible. Remember how exited everyone got during the lead up to replicel's results and then the crash when their expectations where smashed to shit? There are still many unknown mechanisms and as I have learned through my studies usually when you target or eliminate one variable many unexpected outcomes arise. I like your optimism but I believe it is extremely premature.Leave a comment:
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You keep saying that it has nothing to do with the immune system, you do realize that PGD2 is intimately connected with the immune system don't you? PGD2 is produced by mast cells (involved in the immune system), it then recruits helper t cells, eosinophils and basophils (all white blood cells & part of the immune system). So saying PGD2 is the problem and at the same time saying it has nothing to do with the immune system makes you sound extremely ignorant and uninformed. PGD2 may very well be a critical component to solving hair loss, but to say that's it we have found it, NW7---> NW1 is very irresponsible. Remember how exited everyone got during the lead up to replicel's results and then the crash when their expectations where smashed to shit? There are still many unknown mechanisms and as I have learned through my studies usually when you target or eliminate one variable many unexpected outcomes arise. I like your optimism but I believe it is extremely premature.Leave a comment:
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not really a theory....
We know that some prostaglandins GROW HAIR and some prostaglandins INHIBIT HAIR GROWTH.
Bald people have more of the prostaglandin that inhibits hair growth.
What do you think will happen once you block that protein? Why wouldn't it start growing? What's stopping it?
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~ NW2
regimen:
toco-8
nizoral 2%
revivogen
about to start OC0459 that's why I dropped fin in order to measure my real results
A really relevant and recent example of how theory doesn't always support reality - REPLICEL. The theory is great but it's not as rosy in reality (hopefully they improve on their treatment in their next clinical trials).
A reason why the Replicel boards were full of shit was because there were loads of people like you expecting a black or white answer to a black and white question - Does it work or doesn't it? But you must understand it's not as simple as that. But I see you reacting in a similar way to this finding.
Lets slow the pace down and stop suggesting this is the cure to baldness. As far as I'm aware nothing has been found that PDG2 is an isolated cause of hair loss.
How are you finding your regimen, what results have you had?Leave a comment:
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I really really hope you do :-).
But then again, I'm not saying it won't. The theory sounds brilliant. I just think it's irresponsible to go around making wild accusations that this is the cure to baldness. It is all theory at the moment after all.
By the way what stage of loss are you at and what treatments are you using if any?
not really a theory....
We know that some prostaglandins GROW HAIR and some prostaglandins INHIBIT HAIR GROWTH.
Bald people have more of the prostaglandin that inhibits hair growth.
What do you think will happen once you block that protein? Why wouldn't it start growing? What's stopping it?
----------------
~ NW2
regimen:
toco-8
nizoral 2%
revivogen
about to start OC0459 that's why I dropped fin in order to measure my real resultsLeave a comment:
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I really really hope you do :-).
But then again, I'm not saying it won't. The theory sounds brilliant. I just think it's irresponsible to go around making wild accusations that this is the cure to baldness. It is all theory at the moment after all.
By the way what stage of loss are you at and what treatments are you using if any?Leave a comment:
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I think you have been brain washed by the guys at the other forums 2020?Leave a comment:
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Well then my body is lame.
Another question I've thought of... how does PGD2 tie in to DHT? For a long time we thought DHT was the main culprit in genetic hair loss, and there's no doubt that reducing it stops, slows or reverses the process. What's up with that?Leave a comment:
Leave a comment: