OC000459? (Yes that's its name)

[2020]

Be careful guys, no one on this forum actually knows what they are talking about. 2020, why say "it will work". Are you trained in medicine and conducted the studies?

Current drugs that are on the market will not be forumated for baldness so results could be very disappointing at best.

I'm really excited by PGD2 findings but is it the cause? Not necessarily. It could be a bi product once follicles are destroyed anyway?

yes it will work because up to this point we have never looked at prostaglandins and instead just blamed it all on DHT.

minoxidil works at growing hair. Why? Because it apparently increases PGE2 levels(good prostaglandins). So much for the "circulation" theory....
latisse works too. Why? increases PGF2alpha.

emu oil, with which some people regrew hair lines, contains Omega 3 which is a WEAK PGD2 INHIBITOR which is also ANTI-INFLAMMATORY! Inflammation and MPB link comes back again!

some guy on HLH has completely regrown his hairline using sulfasalazine. Well guess what: it's an anti-inflammatory and it also reduces levels of PGD2.... coincidence that it helped him?


This is all too perfect for this to not work. Correcting prostaglandin levels will cure MPB 100%

[gutted]

i really do believe there is a reasonable amount of evidence to suggest this may allow the scarred hair follicles to regenerate, whethere this goes anywhere though is anyones guess. The molecule in question may not get into the deeper layers of the dermis.

http://www.nature.com/jid/journal/v132/n1s/full/jid201291a.html

[clandestine]

We shouldn't by any means jump to conclusions.

That said, I understand 2020 frequents a variety of hairloss forums, so his observations may indeed have some credence to them.

[Kirby_]

2020 is hairloss forums.

[WillhasWill]

minoxidil works at growing hair.

It's no where near a cure.

latisse works too.

Currently produced for eyelashes, show me the picture it's an effective treatment for hair loss. It may be one day but they are working on this aren't they.

emu oil, with which some people regrew hair lines

Great! Where are the pics, send us the links

some guy on HLH has completely regrown his hairline using sulfasalazine.

Great! Where are the pics, send us the links

[Tacola]

Can anyone name any food or drugs where one can find this PGE2 stuff?

[2020]

It's no where near a cure.

of course not.... because it's not addressing the MAIN cause of hair thinning - EXCESSIVE PGD2.

minimize bad prostaglandins = cure.

Currently produced for eyelashes, show me the picture it's an effective treatment for hair loss. It may be one day but they are working on this aren't they.

check out all these women who are reporting thicker hair when applied to scalp:

http://www.nytimes.com/2011/05/05/fashion/05SKIN.html

http://today.msnbc.msn.com/id/45259102/ns/today-today_health/t/latisse-your-dome-eyelash-enhancer-also-thickens-thin-hair/

also: the company that makes latisse is currently conducting a study on its hair effects:

http://clinicaltrials.gov/ct2/show/NCT01325337

^ obviously something is happening....

Great! Where are the pics, send us the links

here's one:

http://www.hairlosshelp.com/forums/messageview.cfm?catid=10&threadid=96765

check out youtube: lots of women with positive feedback from emu oil.

Great! Where are the pics, send us the links

he never showed any pics but I see no reason why he would lie about it....
the guy was diagnosed with arthritis. He took sulfasalazine and unexpectedly regrew his hairline. He simply reported his unexpected side effects. No reason to lie since most of us won't even bother trying that drug due to its side effects.

Also: check out this study:

"Sulfasalazine may be effective in alopecia areata treatment"

http://www.modernmedicine.com/modernmedicine/Dermatology/Sulfasalazine-may-be-effective-in-alopecia-areata-/ArticleStandard/Article/detail/666211

Twenty-two of 26 patients completed the study. Overall, results showed that 68.2 percent (15 of 22) of patients responded to therapy with 27.3 percent (six of 22 patients) and 40.9 percent (nine of 22 patients) demonstrating a complete hair re-growth and a partial hair re-growth, respectively.

[2020]

Can anyone name any food or drugs where one can find this PGE2 stuff?

your PGE2 levels are fine. It's PGD2 that's off the charts. Minimizing PGD2 is the key and that's where this drug comes in....

[WillhasWill]

Most of those are not even related to MALE PATTERN BALDNESS. And you sound so sure that you know the cure a few posts back.....

[Tacola]

And this is done by taking this drug? There is no other things that can lower this other PG?

[2020]

Most of those are not even related to MALE PATTERN BALDNESS. And you sound so sure that you know the cure a few posts back.....

it doesn't matter what your condition is.... All that these examples prove is that obviously there is a clear connection between hair growth and the levels of certain prostaglandins.
People with normal levels of prostaglandins don't go bald while us baldies with excessive PGD2 do.... that's what that study was about!
Why wouldn't blocking the protein that's responsible for hair thinning actually STOP hair from thinning?

[2020]

And this is done by taking this drug? There is no other things that can lower this other PG?

yes... diet and exercise won't do jack in this case either

[2020]

what the hell.... a patent by Cotsarelis filed in 2007 describes a way to treat MPB by reducing PGD2 levels:

A method of treating an androgenetic alopecia (AGA) in a scalp of a subject, comprising the step of contacting said subject with a compound or composition capable of inhibiting or decreasing the activity, level, signaling downstream receptor pathway activity of prostaglandin D2, or their combination in said scalp, thereby treating an AGA in a scalp of a subject.

http://www.google.com/patents/US20110021599

He knew about this 5 years ago???

[sausage]

Is this stuff not licensed or whatever checks etc it has to go through?

Surely it is illegal to send over a sample of this stuff to some random guy on a forum to try it out?

This stuff hasn't been approved so surely it can't be sent out willy nilly.

[2020]

Is this stuff not licensed or whatever checks etc it has to go through?

Surely it is illegal to send over a sample of this stuff to some random guy on a forum to try it out?

This stuff hasn't been approved so surely it can't be sent out willy nilly.

what are you talking about?