OC000459? (Yes that's its name)

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  • Kirby_
    Senior Member
    • Jan 2012
    • 439

    #16
    ^ rev and cur aren't effective, surely? I can't recall any actual scientific evidence being cited anywhere...

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    • 2020
      Senior Member
      • Jan 2012
      • 1513

      #17
      Originally posted by Davey Jones
      Ohhhhhhh, seems a lot less shady without that. Well, I'm interested to see how that turns out. Someone who frequents both forums should keep us updated. 2020_2 wouldn't happen to be you, would it 2020?
      yup, that's me

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      • Johny.track131
        Senior Member
        • Feb 2012
        • 100

        #18
        Originally posted by Kirby_
        ^ rev and cur aren't effective, surely? I can't recall any actual scientific evidence being cited anywhere...
        Here you go my man http://www.hairlosshelp.com/forums/m...threadid=80854

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        • 2020
          Senior Member
          • Jan 2012
          • 1513

          #19
          Attention All Balding Males: Resveratrol To Your Rescue



          ^ supposedly it's helpful....I still think you should stick with "proven" treatments....

          Comment

          • Johny.track131
            Senior Member
            • Feb 2012
            • 100

            #20
            also isnt it generally helpful to your health? what would be any downside in taking it daily? Unless it's really expensive, i dont see any problem with something that's gonna make you live longer AND supposedly good for your hair! And add circ too for best results, i mean if there's no loss then where's the harm? Also i read in one forum of a dude that used to eat a garlic clove a day (Full of Res from what i can figure) and he lost the shedding and itching, it only came back when he stopped (probably cause the suppressed effects werent suppressed anymore)

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            • Kirby_
              Senior Member
              • Jan 2012
              • 439

              #21
              Originally posted by 2020
              ^ supposedly it's helpful....I still think you should stick with "proven" treatments....
              Yeah, I'm quite open about dabbling in SOME supplements here or there, but not at the expense of fin, no way.

              Comment

              • clandestine
                Senior Member
                • Aug 2011
                • 2002

                #22
                bump

                10char

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                • 2020
                  Senior Member
                  • Jan 2012
                  • 1513

                  #23
                  lol not a single post since I took a break for two weeks.... this thread should be booming

                  anyways, apparently this drug has already finished phase 2 and it was proven to be very effective:



                  ^ I wonder if any of those people in those studies noticed any improvement to their hair....

                  Comment

                  • gutted
                    Senior Member
                    • Jan 2011
                    • 1397

                    #24
                    for all those experimenters out there try this internally -> http://www.ncbi.nlm.nih.gov/pubmed/10457118

                    its better known as omega 3.
                    fatty acids may be the key to hair regeneration.

                    Comment

                    • greatjob!
                      Senior Member
                      • Aug 2011
                      • 909

                      #25
                      Originally posted by gutted
                      for all those experimenters out there try this internally -> http://www.ncbi.nlm.nih.gov/pubmed/10457118

                      its better known as omega 3.
                      fatty acids may be the key to hair regeneration.
                      Studies like this dealing with immune response are what I'm putting my money on for the end game cure.

                      Comment

                      • clandestine
                        Senior Member
                        • Aug 2011
                        • 2002

                        #26
                        Anyone with a knowledge of this (OC000459) know what it's side effect profile is (if any)?

                        Comment

                        • 2020
                          Senior Member
                          • Jan 2012
                          • 1513

                          #27
                          Originally posted by clandestine
                          Anyone with a knowledge of this (OC000459) know what it's side effect profile is (if any)?
                          oh that's on the first page on their site:

                          Its lead drug candidate OC000459 is a once-daily oral CRTH2 antagonist in Phase IIb clinical trials that has demonstrated efficacy in asthma, allergic rhinitis and allergic conjunctivitis along with an excellent safety profile.
                          even when taken ORALLY at high doses (100mg+/daily), it still was shown to be very safe.

                          I've actually contacted the company to ask if any of the subjects reported an increase of hair growth... awaiting their reply

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                          • gutted
                            Senior Member
                            • Jan 2011
                            • 1397

                            #28
                            Originally posted by greatjob!
                            Studies like this dealing with immune response are what I'm putting my money on for the end game cure.
                            no not really.
                            the immune response is there for a reason, it doesnt just happen to start attacking itslelf. something is provoking it. the end game cure is figuring out what that something is.

                            Comment

                            • Davey Jones
                              Senior Member
                              • Apr 2012
                              • 356

                              #29
                              Originally posted by gutted
                              no not really.
                              the immune response is there for a reason, it doesnt just happen to start attacking itslelf. something is provoking it. the end game cure is figuring out what that something is.
                              Often times, that "something" provoking an immune response is totally innocuous. Think allergies to dust, pet hair, etc. It is an immune overreaction that needs controlled.

                              I'm not saying that I agree that the immune response is the end game to hairloss treatments; I'm just saying that the immune system itself (and not the cause) is the problem in some cases.

                              Comment

                              • gutted
                                Senior Member
                                • Jan 2011
                                • 1397

                                #30
                                Originally posted by Davey Jones
                                Often times, that "something" provoking an immune response is totally innocuous. Think allergies to dust, pet hair, etc. It is an immune overreaction that needs controlled.

                                I'm not saying that I agree that the immune response is the end game to hairloss treatments; I'm just saying that the immune system itself (and not the cause) is the problem in some cases.
                                its possible that its bacteria, that lives on your scalp, but overgrows beyond control, provoking the immune reaction and thus scarring of the follcile.

                                MPB is not so much different from alopecia areata, alopecia areata is also thought to be the body attacking its only follicles, (bacteria have also been implicated) causing hair to shed prematureley this is what is know in MPB as "DHT causing early entry into telogen phase" when truely it is not dht but the body.

                                your imune system is only doing its job and protecting the body, dont blame the immune system, blame yourself.

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