CB-03-01 - new antiandrogenic

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  • StayThick
    Senior Member
    • Oct 2012
    • 624

    #46
    I've heard some rumblings about CB but yet to speak to anyone that has actually used it at this point. I would definitely like try this, but there is too many unknown variables at the moment. Like where to buy it, is the source legit, side effects, vehicle to use?

    Unfortunately I'm not a chemist, I wouldn't trust myself mixing potions in my house and applying products from China, but I feel this has a ton of upside yet nobody talks about it.

    Anybody trying CB at the moment? Where are you buying it? How are you applying it?? Etc..

    Comment

    • mpbsucks
      Senior Member
      • Oct 2012
      • 101

      #47
      Originally posted by Knockin on NW4
      And we have PICS of a member who used cb + minox for a whole year, he has had good regrowth using a cream vehicle at 1% . PM lilpauly aka mark if u want to join our community and get in on our Group Buys. We can get CB for $105 per g if we get a large enough order. Everything gets tested. 1 gram will last 100 days @ 1% in a 1ml application. 2% would even be affordable at $105 per gram. We can get any research chem. SABA Gel, vitamin D analogue, RU, ect. We are even working on getting BNP and CNP, plus a HSC alternative. We have a super organized forum with full text libraries on the latest hairloss advancements (not misleading abstracts and bro science). There are no fees, nor requirements to buy products, just rules and etiquette to keep us sufferers civilized. PM Lilpauly, you will regret not joining us.
      hey man, tell me how to join your forum please. I will be a good contributor...

      Comment

      • unwheel
        Junior Member
        • Feb 2013
        • 5

        #48
        Does anyone know how cost effective cb is? I'm aware it's more expensive per gram than ru but can we use a lower dose to get the same effect? Perhaps use it every two days instead of every day? Right now I'm using about 1.5ml of 5% ru a day and this would be far too expensive for me at current cb prices, even at group buy prices

        Comment

        • hellouser
          Senior Member
          • May 2012
          • 4419

          #49
          Originally posted by unwheel
          Does anyone know how cost effective cb is? I'm aware it's more expensive per gram than ru but can we use a lower dose to get the same effect? Perhaps use it every two days instead of every day? Right now I'm using about 1.5ml of 5% ru a day and this would be far too expensive for me at current cb prices, even at group buy prices
          CB is 2-4X as effective as Finasteride. Per 1ml application, you only need 1% mix as even Cosmo's trials showed a very small difference at 5% from 1%.

          Comparing it to RU is difficult since its not as thoroughly tested.

          Comment

          • clandestine
            Senior Member
            • Aug 2011
            • 2002

            #50
            Originally posted by hellouser
            CB is 2-4X as effective as Finasteride. Per 1ml application, you only need 1% mix as even Cosmo's trials showed a very small difference at 5% from 1%.

            Comparing it to RU is difficult since its not as thoroughly tested.
            Have they found an appropriate vehicle yet? Does Cosmo Cream work? Oleum Alcohol?

            Comment

            • Cob984
              Senior Member
              • Sep 2012
              • 526

              #51
              And CB comes with no sides inspite of being so effective? this is just too good to be true, i cant believe cosmo isnt spending every waking minute trying to get a hairloss product out, just doesnt make sense

              Comment

              • clandestine
                Senior Member
                • Aug 2011
                • 2002

                #52
                Originally posted by Cob984
                And CB comes with no sides inspite of being so effective? this is just too good to be true, i cant believe cosmo isnt spending every waking minute trying to get a hairloss product out, just doesnt make sense
                Pretty sure t will be released for acne first.

                Comment

                • hellouser
                  Senior Member
                  • May 2012
                  • 4419

                  #53
                  Originally posted by clandestine
                  Have they found an appropriate vehicle yet? Does Cosmo Cream work? Oleum Alcohol?
                  The vehicle they were using was only stated as 'OL/PG'

                  PG should be pretty obvious as 'polypropylene glycol' but OL could mean oleum (though isnt that an acid???) or Oleyl.

                  Comment

                  • hellouser
                    Senior Member
                    • May 2012
                    • 4419

                    #54
                    Originally posted by Cob984
                    And CB comes with no sides inspite of being so effective? this is just too good to be true, i cant believe cosmo isnt spending every waking minute trying to get a hairloss product out, just doesnt make sense
                    Its crazy too, I think I read somewhere that their results with CB against acne were mediocre but from what I've seen with CB against hairloss has been ridiculously impressive.

                    Comment

                    • Cob984
                      Senior Member
                      • Sep 2012
                      • 526

                      #55
                      WTF? surely a hair loss breakthrough is more media/news worthy than acne trials?
                      this is just flat out illogical

                      Comment

                      • hellouser
                        Senior Member
                        • May 2012
                        • 4419

                        #56
                        Originally posted by Cob984
                        WTF? surely a hair loss breakthrough is more media/news worthy than acne trials?
                        this is just flat out illogical
                        Well, not exactly. We still don't know what the vehicle should be for maximum efficacy and we dont know if it works for everyone as well as it did for Cosmo's own patients.

                        But, from baseline to 4 weeks of application the follicle count went up from 71 to 109 per cm/2 using only a 1% solution. At 5% the density rose from 73 to 111 grafts per cm/2, so its easy to see that not a lot of CB is needed to get the same results (kind of like finasteride).

                        So, using the one example, density was 54% higher. Whats crazy is that this number is ridiculously higher than even Replicel's initial Phase I results using stem cells! How the hell could THAT be?

                        CB does look very promising though. Combine that with Minox and maybe even with Keratene/Fin and you should have a ridiculous arsenal against hair loss. I'd throw in RU into the mix, maybe using CB on its own but Minox/RU in a single solution and Keratene every 2nd day just to avoid any potential side effects. Of course, Nizoral and some Saw Palmetto based shampoos should help a little as well.

                        Comment

                        • StayThick
                          Senior Member
                          • Oct 2012
                          • 624

                          #57
                          Originally posted by hellouser
                          Well, not exactly. We still don't know what the vehicle should be for maximum efficacy and we dont know if it works for everyone as well as it did for Cosmo's own patients.

                          But, from baseline to 4 weeks of application the follicle count went up from 71 to 109 per cm/2 using only a 1% solution. At 5% the density rose from 73 to 111 grafts per cm/2, so its easy to see that not a lot of CB is needed to get the same results (kind of like finasteride).

                          So, using the one example, density was 54% higher. Whats crazy is that this number is ridiculously higher than even Replicel's initial Phase I results using stem cells! How the hell could THAT be?

                          CB does look very promising though. Combine that with Minox and maybe even with Keratene/Fin and you should have a ridiculous arsenal against hair loss. I'd throw in RU into the mix, maybe using CB on its own but Minox/RU in a single solution and Keratene every 2nd day just to avoid any potential side effects. Of course, Nizoral and some Saw Palmetto based shampoos should help a little as well.
                          Are you using CB personally? If so, through what vehicle and what source are you using to buy it from?

                          What are your results? I have yet to see anyone on this forum discuss applying this and discussing the results. Anyone? I ask because I'm very interested just clueless on where to buy and how to apply.

                          Comment

                          • hellouser
                            Senior Member
                            • May 2012
                            • 4419

                            #58
                            Originally posted by StayThick
                            Are you using CB personally? If so, through what vehicle and what source are you using to buy it from?

                            What are your results? I have yet to see anyone on this forum discuss applying this and discussing the results. Anyone? I ask because I'm very interested just clueless on where to buy and how to apply.
                            You can order CB from Kane. It's pricey though, but at 1% (10mg/1ml) will last you about 100 days if you buy 1gram @ $200.

                            As for vehicle, nobody knows whats best. I'll be trying a combination of Everclear/PG and Oleyl/PG. Others may be using the Cosmo cream, or something else. Right now its tough to say whats best, because nobody knows! I'll be getting CB sometime soon, probably within the next month.

                            I'll definitely make updates if I get good progress with it though. Hopefully I do, but my regiment will be:

                            1X Daily Before Bed (midnight): 1ml of CB at 1% (10mg)
                            1X Daily at 6pm: 1ml of Minoxidil 5% with 50-100mg of RU mixed in as well
                            2-4X Weekly: Nizoral
                            1X Daily: 160mg of Saw Palmetto

                            I may substitute Saw Palmetto with Keratene if I still don't get results. However, I'm still planning a consultation with Dr. Gho to fix my hairline. Hopefully this route will last me 2+ years without any loss, that way I can go for a procedure with Aderans when available (hopefully next year). This would ultimately cure me but lets remain hopeful! I'm currently about NW3 with thinning (though going through a really bad shed right now after switching to 5% Minox from 2% in December). I'm sure it will all grow back considering its most likely just a Minox shed, I cant see how I could lose so much density in 3 months when its taken me 10 years to get to NW3.

                            Comment

                            • UK Boy
                              Senior Member
                              • Apr 2011
                              • 240

                              #59
                              I'd love to get on CB but I'm sh*t scared of using untested chemical compounds from illegal labs. This is where the system is so crap - the FDA holds eveything up to make sure stuff is 100% but by holding it up so long they drive people to getting the stuff through dodgy foreignlabs. Surely the safest thing is to allow reputable companies going through clinical trials to start selling it after phase I safety trials. There would be no promises as too efficacy but it'd be up to the consumer, at least it'd be safe and the company could use the profits for continuing trials.

                              I really don't get why Cosmos are concentrating on acne, there's tonnes of acne treatments. If people are gonna be using 1% for hair does that mean we could use the acne version for hair loss? If so I guess I'll just have ta hold on til that comes.

                              How comes so many if you feel so safe using untested, illegal chemical compounds. I saw in the other thread Hellouser told someone to "try RU or CB" as if it were totally normal and it was just totally safe OTC stuff that he was talking about.

                              Comment

                              • burtandernie
                                Senior Member
                                • Nov 2012
                                • 1563

                                #60
                                If CB is actually a super powerful anti androgen that fights with not just DHT but also T and it has some anti inflammatory properties then it could have big results given the right vehicle. MPB is androgens and inflammation if you stop that your stopping MPB. I think CB has the potential to stop MPB forever if its strong enough and Im not sure that is an exaggeration time will tell though its a long uncertain road.
                                I do wish it works out for acne though because I wouldnt mind seeing acne and MPB both given much better treatments

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