I think I've hacked it

[fred970]

It just might Fred, it just might. Sometimes the most intuitive minds and greatest discoveries come from outside the lab. How do you know FGF11 isn't like Matt Damon in, "a beautiful mind"?

You just mixed up Russel Crow with Matt Damon and A Beautiful Mind with Good Will Hunting.

[x4342]

You just mixed up Russel Crow with Matt Damon and A Beautiful Mind with Good Will Hunting.

Indeed, and the distinction is everything.

Is he saying that FGF11 is a brilliant scientist who could cure hair loss if only he had a good psychologist? -Or is he saying that FGF11 thinks he's cured hair loss and has a full head of hair while the rest of the world sees him as a schizophrenic Norwood 6?

[jamesst11]

You just mixed up Russel Crow with Matt Damon and A Beautiful Mind with Good Will Hunting.

hahaha... o.k. o.k. fair enough. I am just too bitter against all the NW1's that I confuse them.

[jamesst11]

You just mixed up Russel Crow with Matt Damon and A Beautiful Mind with Good Will Hunting.

hahaha... o.k. o.k. fair enough. I am just too bitter against all the NW1's that I confuse them.

[jjo]

Yeah, f-ck the qualified scientists who are on this. The cure for hair loss will be found in FGF11's basement!

+1

[pixels]

+1

Maybe Nigram and FGF11 could have a sleep over and solve all our problems.

If FGF11 just added acell to his basement solution we might be onto a winner.

Look out for the photographic evidence coming at you via a pixel art blog in India.

[fred970]

Maybe Nigram and FGF11 could have a sleep over and solve all our problems.

If FGF11 just added acell to his basement solution we might be onto a winner.

Look out for the photographic evidence coming at you via a pixel art blog in India.

It's funny how people never learn. How many pages was the Nigam thread?

[Hairmore]

Indeed, and the distinction is everything.

Is he saying that FGF11 is a brilliant scientist who could cure hair loss if only he had a good psychologist? -Or is he saying that FGF11 thinks he's cured hair loss and has a full head of hair while the rest of the world sees him as a schizophrenic Norwood 6?

A norwood 6 who still gets the nobel price in the end because his ideas were used by the entire industry and became the new standard for treating hair loss.

[FGF11]

look, my tolerance for stupidity is low. So please stop posting none sense here.

Also guess what?! if you stop posting to this thread, this thread won't grow in pages, and I will stop receiving emails telling me I have nonsense posted on this thread. Okay?

Meanwhile, you can read one of the examples of self-experimentation that actually led to Nobel Prize in Medicine:

http://blogs.scientificamerican.com/guest-blog/when-scientists-experiment-on-themselves-h-pylori-and-ulcers/

(if you can read two pages of something that is not related to wallowing in self-pity ofcoures) .

and stop comparing me with charlatans who try to sell you stuff.

I noticed in another thread, just above mine, people are referring others to products in amazon with next to zero scientific evidence and gaining commission through referrals. How lowly is that?!

so unless I try to sell you something, or refer you, or raise false hope, please stop being a downer and a dummy, and stop posting in this thread for fck's sake.

[pixels]

Here what you sell is hope. This site has teenage members suicidal and sad.

If what you're selling turns out to be mumbo jumbo you deserve to have your ass kicked

I hope you're right.

[jjo]

hey FGF11, we haven't heard from you in a while.. hows the study going?

[FGF11]

A vial of lentiviral vectors I have created is sitting somewhere close and I’m arguing to either intradermally inject them or not. I have not yet made the decision. This vial of lentiviral vectors can potentially (with a high probability) bring my hair back at the site of injection, but as of now, I don’t have the balls to do it. I already had AAV antigens, so couldn’t use them. I’ve developed a lentiviral system using a bi-cistronic expression of shRNA and a catalytically dead CRISPIR (CRISPRi) both targeting AR in a VSV-G-pseudotyped replication-deficient lentivirus. But I don’t know what can happen upon injection, I simply don’t have the balls. This can silence AR probably up to 99% for a couple of years or more but can also cause cancer, with a low probability, but that can happen. There is almost a zero chance for the virus to go systemic. My lentiviral genes are under strong promoters and these promoters can sit in wrong places when integration happen and purely out of murphy's law cause cancer. You guys probably have absolutely no idea what I wrote here but that's the current state of affairs.

[fred970]

Thanks Dr. Nigam!

[Link Mahboi]

Thanks Dr. Nigam!

Oh please, just shut up.

[Link Mahboi]

A vial of lentiviral vectors I have created is sitting somewhere close and I’m arguing to either intradermally inject them or not. I have not yet made the decision. This vial of lentiviral vectors can potentially (with a high probability) bring my hair back at the site of injection, but as of now, I don’t have the balls to do it. I already had AAV antigens, so couldn’t use them. I’ve developed a lentiviral system using a bi-cistronic expression of shRNA and a catalytically dead CRISPIR (CRISPRi) both targeting AR in a VSV-G-pseudotyped replication-deficient lentivirus. But I don’t know what can happen upon injection, I simply don’t have the balls. This can silence AR probably up to 99% for a couple of years or more but can also cause cancer, with a low probability, but that can happen. There is almost a zero chance for the virus to go systemic. My lentiviral genes are under strong promoters and these promoters can sit in wrong places when integration happen and purely out of murphy's law cause cancer. You guys probably have absolutely no idea what I wrote here but that's the current state of affairs.

FGF11, I understand the risks and can comprehend if you decide to not do it, but just think how this could change the game for us and for good if that works, I believe some things are worth a leap of faith.