Updated Research and Knowledge - Cutting Edge

[potato1987]

Sorry what does this mean?

[SriHanuman]

F****** double post

[SriHanuman]

The mice study seems great! I am going to go ahead and use

http://www.amazon.co.uk/Herb-Pharm-Extract-Liquid-29-6ml/dp/B001E0X2EG/ref=sr_1_1?ie=UTF8&qid=1449612675&sr=8-1&keywords=herb+pharm+olive+leaf+extract+liquid+29.6ml+1floz

with tretinoid as it increases absorption. If it works similar on humans I can expect great results...

[potato1987]

Thanks for the response,
Would it do any good without minox? minox (and I know there are doubters, gave me puffy eyes and reduced collagen). I wouldn't lie about it and nor would others. I didn't know it was a symptom I just thought it was lack of sleep but the bags got darker and my skin got thinner the longer the weeks went on.

[InBeforeTheCure]

This may interest you.

Hair follicles have characteristic sizes corresponding to their cycle specific stage. However, how the anagen hair follicle specifies its size remains elusive. Here, we show that in response to prolonged ectopic Wnt10b-mediated β-catenin activation, regenerating anagen hair follicles grow larger in size. In particular, the hair bulb, dermal papilla and hair shaft become enlarged. While the formation of different hair types (Guard, Awl, Auchene, and Zigzag) is unaffected. Interestingly, we found the effect of exogenous WNT10b was mainly on Zigzag and less on the other kinds of hairs. We observed dramatically enhanced proliferation within the matrix, DP and hair shaft of the enlarged AdWnt10b-treated hair follicles compared with those of normal hair follicles at P98. Furthermore, expression of CD34, a specific hair stem cell marker, was increased in its number to the bulge region after AdWnt10b treatment. Ectopic expression of CD34 throughout the ORS region was also observed. Many CD34 positive hair stem cells were actively proliferating in AdWnt10b-induced hair follicles. Importantly, subsequent co-treatment with the Wnt inhibitor, DKK1, reduced hair follicle enlargement, decreased proliferation and maintained proper hair stem cell localization. Moreover, injection of DKK1 during early anagen significantly reduced the width of prospective hairs. Together, these findings strongly suggest that a balance of Wnt10b/DKK1 governs reciprocal signaling between cutaneous epithelium and mesenchyme to regulate proper hair follicle size.

Link to paper: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4383245/