Approved drug that could save our dermal papilla cells! 'Troxerutin'

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  • noisette
    Senior Member
    • Jun 2013
    • 259

    #16
    Originally posted by lacazette
    Hey seuxin t'es Français du coup?
    c'est pas fait pour la perte de cheveux a la base, c'est un medicament deja sur le marché depuis des années, mais l'etude que j'ai posté date de ya 2 mois, et ils disent que ca serait une approche efficace pour lutter contre la chute de cheveux
    donc oui c'est deja dans nos pharmacies, j'ai chercher en France ils vendent troxerutin en poudre, 3500g dans 10 sachets, a melanger dans l'eau
    le probleme c'est qu'on sait pas a quel dose en prendre, j'hesite entre 50/100mg par jour ou 400/500
    Hey Lacazette
    I found this, on a gel form... Perhaps we can test it directly on hairs.

    Comment

    • noisette
      Senior Member
      • Jun 2013
      • 259

      #17
      I found a product with Troxerutin for hair loss. Use this product with a dermaroller.

      source : http://www.laser-ipl-brighton.co.uk/hair-table.html

      "Hair ****tail Plus

      Product
      Toskani's specially designed composition for hair loss treatment combined with the knowledge and experience of Mesotherapy practitioners provides the ultimate formula for hair loss treatment.

      Indications

      Clean the surface to be treated
      Divide the zone in small sub-areas
      Apply the derma roller in different directions (vertical, horizontal and transverse) while dripping on the surface
      Repeat the same steps in other sub-areas

      Composition

      Dexpanthenol
      Taurine
      Glutathion
      Biotine
      Fe-Gluconat
      Thiamine
      Troxerutine
      Sabal serrulata (anti-androgenous action)
      "

      Comment

      • lacazette
        Senior Member
        • May 2015
        • 394

        #18
        Good find noisette, that confirms that it can be good to add this drug with our current regimen. Still wondering if take it orally or topically, well maybe I'll do bought

        @Furious maybe, even if the idea sounds weird to put hemorroids gel on our head x) but well it seems to have potential if we believe those researchers, so why not hehe

        Comment

        • noisette
          Senior Member
          • Jun 2013
          • 259

          #19
          Originally posted by lacazette
          Good find noisette, that confirms that it can be good to add this drug with our current regimen. Still wondering if take it orally or topically, well maybe I'll do bought

          @Furious maybe, even if the idea sounds weird to put hemorroids gel on our head x) but well it seems to have potential if we believe those researchers, so why not hehe
          You're welcome bro

          I find this patent called Active mixtures comprising acylated oligopeptides and troxerutin(the authors seems to be french like us ) useful for increasing hair growth and in particular density of eyelashes and eyebrows.
          This a solution, a topical for eyelashes, hair growth.
          Suggested is an active mixture comprising (a) acylated oligopeptides and (b) troxerutin, useful for increasing hair growth and in particular density of eyelashes and eyebrows.


          A quote from this patent :

          "The preparations can also contain water in a quantity of up to 99 % b.w., preferably 5 to 80 % b.w., based on the total weight of the preparation.
          Industrial application
          [0064]
          Another object of the present invention refers to a non-therapeutic method for increasing hair growth in general, and increasing hair shaft elongation and density of eyelashes and eyebrows in particular, by topical administration of the mixture of components (a) and (b) or the composition comprising said mixture to human scarp or skin.
          [0065]
          Finally, the invention encompasses the use of the mixture of components (a) and (b) or the composition comprising said mixture for increasing hair growth, in particular for increasing hair shaft elongation and density of eyelashes and eyebrows.
          Examples
          Examples 1 to 3, Comparative Examples C1 to C4
          [0066]
          In-vivo studies were conducted with a panel of 10 subjects. Serum comprising the actives in different concentrations was applied once a day in the evening using an eyelash brush at the roots of the lashes. The duration of the study was 6 weeks; evaluation took place after 14, 28 and 42 days. Eyelash density and eyelash volume, distal length and width were evaluated using high resolution reverse photo engineering. The results as the average of values from the left and the right eyelash are reported in Table 1. Examples 1 to 3 are according to the invention, examples C1 to C4 serve for comparison. Table 1
          Improvement in eyelash drensity compared to baseline at day 0
          Ex. Serum 14 d 28 d 42 d
          C1 2 % Sympeptide® XLash1) + 2.3 % + 4.5 % + 9.0 %
          1 2 % Sympeptide® XLash + 0.1 % Troxerutin + 9.5 % + 15.1 % + 22.2 %
          C2 5 % Sympeptide® XLash + 8.5 % + 34.4 % + 42.5 %
          2 5 % Sympeptide® XLash + 0.1 % Troxerutin + 16.5 % + 42.6 % + 49.7 %
          C3 10 % Sympeptide® XLash + 31.2 % + 52.5 % + 64.5 %
          3 10 % Sympeptide® XLash + 0.1 % Troxerutin + 35.7 % + 59.8 % + 71.0 %
          C4 2 % Widelash® 2) + 6.0 % + 12.2 % + 16.1 %
          4 2 % Widelash® + 0.1 % Troxerutin + 9.5 % + 14.2 % + 20.2 % "

          Comment

          • Seuxin
            Senior Member
            • Jan 2014
            • 223

            #20
            Good find....but maybe like Follicept, only effective on the paper.
            Is there a trial ? Or only a simple theorical study ?

            Comment

            • Furious
              Junior Member
              • Mar 2015
              • 24

              #21
              Can you buy the Hair ****tail Plus though? If so I cant find out how.

              Comment

              • noisette
                Senior Member
                • Jun 2013
                • 259

                #22
                Originally posted by Furious
                Can you buy the Hair ****tail Plus though? If so I cant find out how.
                Be careful bro, we don't know if this product is a snake oil or not. I give you this information, but don't buy it without evidences that it works

                Comment

                • lacazette
                  Senior Member
                  • May 2015
                  • 394

                  #23
                  and maybe as it's a coktail there's not as much troxerutin in it as we would need to really help the dermal papilla cells like in the study.
                  I personnaly will begin to try the oral treatment of the drug, as it's more easy ( just powder in water to drink)

                  Merci Noisette, l'etude que t'a posté ca confirme bien que ca pourra au minimum nous aidé un peu pour nos cheveux, ca fera pas de mal en tout cas. Et on sait jamais on pourrait avoir une bonne surprise avec un bon ralentissement de la chute

                  Comment

                  • BBay
                    Member
                    • Jun 2013
                    • 53

                    #24
                    Oral ?? Long term effects always needs to be questioned. Topical if it penetrates the dermis has to be safer.

                    Comment

                    • lacazette
                      Senior Member
                      • May 2015
                      • 394

                      #25
                      Originally posted by BBay
                      Oral ?? Long term effects always needs to be questioned. Topical if it penetrates the dermis has to be safer.
                      Yeah I know dude. But I saw many clinical trials of this trug

                      Some of them were taking 600-1200mg per day during 6months/1 year, and had any side effects
                      Even saw trial who they were taking really high dose 5G/DAY during two months without side effects ,except little grasto problems for few of them

                      So I think it is safe if I take just 100/200 mg per day during 6/12 months, and see how it goes

                      I would like to try topical but im not the sure if the vehicule to treat hemorroids,etc is as good to penetrate and have impact on the follicles, and maybe there's not enough troxerutin concentration on those gels to have any real effects.
                      the oral seems stronger to me to have impact on all the cells oxygen. If I take 1/6 of the normal dose , I think it won't hurt me. But I'll do little more research though before . I keep update

                      Comment

                      • snowie
                        Member
                        • Dec 2014
                        • 38

                        #26
                        Is it this ?

                        Comment

                        • Furious
                          Junior Member
                          • Mar 2015
                          • 24

                          #27
                          This seems to be pils with 300 mg. http://www.ebay.com/itm/252016176621...3AMEBIDX%3AIT#

                          Comment

                          • lacazette
                            Senior Member
                            • May 2015
                            • 394

                            #28
                            Yes its that guys, in France they only sell it in powder sachets. 3500mg in 10 sachets. So i think I'll take 1/2 of a sachet per day

                            Comment

                            • Seuxin
                              Senior Member
                              • Jan 2014
                              • 223

                              #29
                              Hello,

                              I gave this link to some professionnals guys about hairloss.
                              He tolds me that is just fancy words to say that is an anti-oxydant...

                              So, totally bullshit in their opinion.

                              Comment

                              • Dench57
                                Senior Member
                                • Sep 2014
                                • 176

                                #30
                                Is anybody going to give this a try? I may try and get that stuff off eBay

                                Comment

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