Where are the phase IIb results for Bimatoprost?

[champpy]

hey 2014, is that responder rate you mentioned on eyelashes? Or did you see a study of it helping here in other places?

[It's2014ComeOnAlready]

Well, it works better than minox, but it appears to have hit some snags.

info on page 16 of the PDF

http://ir.allergan.com/phoenix.zhtml?p=irol-eventDetails&c=65778&eventID=5206702

[Keki]

Not bad at all, now we need to know what are the sides, the hair shaft sincro like minox and his shedding, the blood pressure drop and the cost, i think it will be expensive as ****

[JayM]

Plus they have said re doing a phase right? Maybe they plan to add with Seti maybe? Those results aren't bad though for 1% and without reducing pgd2/DHT.

Good signs for the people doing group buys for pge2 for sure. Really solid.

[Swooping]

I think it's bad. It would be good 10-15 years ago though. Reason why is that it seems to be pretty much equal to minoxidil 5%. While bimatoprost 3% seems to win barely from minoxidil 5% in the expert panel review and global assesment the subject self assesment seems to favour minoxidil 5% (by almost nothing though).

HOWEVER minoxidil has to cope with the fact that many people don't respond to minoxidil at all because of the lack of sulfotransferase. Also if that is the best picture they have to show then that's not good.

Well up to another phase 2 clinical trial to see if the "enhanced" formulation can bring better results!

Do we have more data? Side effects and such?

SM04554 please surprise us.

[Swooping]

One question. They mention;

Ph 1 PK & Ph 2b studies planned Q1 2016

I don't understand the "Ph 1 PK" part. I assume "PK" stands for pharmacokinetics? Anyone know this?

[Occulus]

Not good - definitely not a major improvement over minoxodil, and several years away.

Back to the drawing board.

[Hairismylife]

The result is so far so good.
Anyone knows the timeframe of it?
This regrowth from 1 month or from 1 year usage has big different meaning.

[barfacan]

Phase 2 lasted a year.

Garbage. They still can't figure it out it seems.

[HelloVera]

'KYTH-105 for hair growth IND filed with FDA earlier this year; Allergan planning Phase 2 proof of concept study' ...Whats this? tried looking for BIM but no details. Don't help the pc crashing on links

[Tenma]

i wasnt expecting much from bimatoprost

im a bit surprised they will insist again with this "enhaced delivery" stuff though

[dus]

Well this sucks, only Sm04554 needs to fail now or under deliver to have no hope for another 3 some years.

[doinmyheadin]

Well, it works better than minox, but it appears to have hit some snags.

info on page 16 of the PDF

http://ir.allergan.com/phoenix.zhtml...ventID=5206702

To say im dissapointed is an understatement. As Swoops said its barely equal to Minox which we all know Minox is a joke. It needs to be at 2 to 3 times better to actually be slightly effective IMO.

[Keeper]

Maybe also the effect is not decreasing like with minox!

So it can have a value, if it works like discribed and its effect is not decreasing by time

[cocacola]

As an ex-minox 5% user, i would say this is fking great and im pissed they wont release it anytime soon. I had to stop minox cuz of annoying sides and its unconvenient (2x a day oily shit). Personally i had strong result on minox which started to lose effectiveness after a year and a half, but if the panel experts conclude that the 3% is similar to minox 5% i would be the first in line to try it.

The key questions are:

1) does it last?
2) how often you have to apply
3) price
4) sides
5) when??

Also seems as they did test 3% but didn't show results from 3% only from 1%. Wish we knew more, but this also makes me believe they could go forward with it. They present this segment as a growth one with a 33% CAGR through the next 5 years, so obviously they want to tap into it.

First time since a while i am actually happy about a development in anti balding treatments. We def need more info on this study and i would try to reach to IR soon, cuz this is not enough and given the relative size of their pipeline i think they underestimate how many people would want to buy this if it has no sides and actually works in line or better than 5% minox.