follicept - what's this?

[Trouse5858]

Says on the website that you may need to discontinue minox for this to work since it is delivering molecules to the follicle. Like too much traffic on a highway I suppose? Anyone know if this would only be for days that you use Follicept, or you could you alternate days since the website says 3 times per week is likely an effective dosage. I really think a multi-layered approach works best for thinning.

[serenemoon]

Says on the website that you may need to discontinue minox for this to work since it is delivering molecules to the follicle. Like too much traffic on a highway I suppose? Anyone know if this would only be for days that you use Follicept, or you could you alternate days since the website says 3 times per week is likely an effective dosage. I really think a multi-layered approach works best for thinning.

I remember that Devon mentioned a while ago that they will be testing on "switching" (switching from Rogaine to Follicept etc.) as well as patients who have not taken any treatment before Follicept. I am definitely eager to see how subjects will respond to switching from Rogaine to Follicept. If there is a noticeable difference on Follicept alone compared to Rogaine alone, we may only need Follicept. I also wonder about the shed after stopping Minoxidil, though in the long run, if Follicept regrows that back and more, the shed can be handled. Maybe there won't even be a shed if IGF-1 acts fast enough. We will see. Only trials can give us the answers that we need. But yeah, I also wonder about the alternate approach too. Hopefully we will have answers in a few weeks. Best of luck to Devon, Dr. Hsu and the Follicept team! I really admire what you guys are doing!

[burtandernie]

Why is IGF considered natural verses say RU or something is it just because IGF-1 is found in the body somewhere even if the amounts they use are not natural?

[Jagger]

Why is IGF considered natural verses say RU or something is it just because IGF-1 is found in the body somewhere even if the amounts they use are not natural?

I think it just has to do with the amount being administered being orders of magnitude below what is required to classify as a drug.

[nameless]

Ha, first you offer a threat that you'll be looking out for "peculiarities" and then ask for discounted stock for looking for a supplier, only to follow up with a critique of the IGF-1 that they ordered...you sound a little delusional. Why don't you leave those types of evaluations to the medical professionals that are doing the research? You sound like the type of person that shows up to a lecture and argues with the professor the whole time.

LOL! Not the brightest bulb in the pack eh?

1. Firstly, you termed my statement that I would keep an eye open for peculiarities a "threat" not me. I never said I was threatening anyone. I just stated a simple fact that I would watch for more peculiarities. That means I'm keeping an open mind is all. It is not a threat. We have all seen many products fail and we've all seen many scams. I'm sure that Devon understands my point.

2. On the issue of the stock, I have a valid point. Not only is Devon asking us for help with the issue of locating the very therapeutic agent that he intends to use in the treatment but he himself also acknowledges that our support is beneficial to him. If Follicept succeeds we were part of the drive whether we get a chance to buy stock at a decent price or not. So why not ask for the opportunity? There's a famous quote that goes, "The only stupid question is the question not asked."

3. It's not that I'm delusional; it's that you're not savy enough to realize that the issues I'm raising are reasonable and even smart. The fact that Devon made a point of responding FIRST to one of the issues I raised shows that he appreciates the relevance of the issues I'm raising. And I do have a valid point that our efforts and support are beneficial to Follicept (whether you grasp that or not) and we know this because Devon himself has said so. And, the fact that our efforts and support have been beneficial to Follicept's cause does not eliminate the possibility that the entire Follicept theme is a bust. Devon himself has even stated that there is a real possibility that this is going to fail.

4. So what I'm doing is merely entertaining numerous points at the same time. It's easy if a person is smart.

[nameless]

just ignore that guy. he's a mess.

Dude you're rude, arrogant, and useless. In fact, there's nothing wrong with my posts. My points are valid even as they have gone over your head.

[DanWS]

Please US customers first, then our international friends, unless there is plenty to do both at once

Don't you think it's kind of obvious it's going to have a US release first? Don't worry, you're front of the queue. As one of your "international friends" from the UK, assuming all goes well I'd like to ask Devon and Follicept to please keep looking into getting a release in the EU and the rest of the world as quickly as possible. Thanks for the updates and good luck.

[joachim]

guys, please don't provoke and play with nameless (jarjarbinx).
because then he always feels the need to fight back with endless posts, useless explanations, pointing out how smart he is and how valid all his nonsense posts are. we all know him from other forums too, and it's always the same there. in most cases, the thread gets completely polluted with word fights and useless explanations. i'm tired of it. let's try to keep it at a minimum.

as a result to my post, you will see him counterattack me with another of his great answers and explanations. but i'm not gonna respond anymore. don't have the time for such games.

[Clion1995]

Second what joachim said. Nameless is a plebeian.

[Jagger]

LOL! Not the brightest bulb in the pack eh?

1. Firstly, you termed my statement that I would keep an eye open for peculiarities a "threat" not me. I never said I was threatening anyone. I just stated a simple fact that I would watch for more peculiarities. That means I'm keeping an open mind is all. It is not a threat. We have all seen many products fail and we've all seen many scams. I'm sure that Devon understands my point.

2. On the issue of the stock, I have a valid point. Not only is Devon asking us for help with the issue of locating the very therapeutic agent that he intends to use in the treatment but he himself also acknowledges that our support is beneficial to him. If Follicept succeeds we were part of the drive whether we get a chance to buy stock at a decent price or not. So why not ask for the opportunity? There's a famous quote that goes, "The only stupid question is the question not asked."

3. It's not that I'm delusional; it's that you're not savy enough to realize that the issues I'm raising are reasonable and even smart. The fact that Devon made a point of responding FIRST to one of the issues I raised shows that he appreciates the relevance of the issues I'm raising. And I do have a valid point that our efforts and support are beneficial to Follicept (whether you grasp that or not) and we know this because Devon himself has said so. And, the fact that our efforts and support have been beneficial to Follicept's cause does not eliminate the possibility that the entire Follicept theme is a bust. Devon himself has even stated that there is a real possibility that this is going to fail.

4. So what I'm doing is merely entertaining numerous points at the same time. It's easy if a person is smart.

Remove the ad hominem attacks from your argument. You are undermining yourself by attacking the posters and not their arguments. I don't know what it is about this community that forces people to take sides against one another. We all have a common goal. Of course there will be disagreements. Present them logically.

[NeedHairASAP]

LOL! Not the brightest bulb in the pack eh?

1. Firstly, you termed my statement that I would keep an eye open for peculiarities a "threat" not me. I never said I was threatening anyone. I just stated a simple fact that I would watch for more peculiarities. That means I'm keeping an open mind is all. It is not a threat. We have all seen many products fail and we've all seen many scams. I'm sure that Devon understands my point.

2. On the issue of the stock, I have a valid point. Not only is Devon asking us for help with the issue of locating the very therapeutic agent that he intends to use in the treatment but he himself also acknowledges that our support is beneficial to him. If Follicept succeeds we were part of the drive whether we get a chance to buy stock at a decent price or not. So why not ask for the opportunity? There's a famous quote that goes, "The only stupid question is the question not asked."

3. It's not that I'm delusional; it's that you're not savy enough to realize that the issues I'm raising are reasonable and even smart. The fact that Devon made a point of responding FIRST to one of the issues I raised shows that he appreciates the relevance of the issues I'm raising. And I do have a valid point that our efforts and support are beneficial to Follicept (whether you grasp that or not) and we know this because Devon himself has said so. And, the fact that our efforts and support have been beneficial to Follicept's cause does not eliminate the possibility that the entire Follicept theme is a bust. Devon himself has even stated that there is a real possibility that this is going to fail.

4. So what I'm doing is merely entertaining numerous points at the same time. It's easy if a person is smart.

a few people on the forum googled "igf-1 for sale" so we're all suppose to get discounts on stock?

Besides being something that warren from something about mary would say, they probably aren't selling stock. At this early of a stage, it's more likely convertible debt.

[Hemo]

I'm actually pretty excited about this even if IGF-1 isn't effective. The fact that there's a new vehicle to deliver treatments in a way that hasn't been possible could be big if Promethon is potentially partnering with other companies. Waiting on clinical trials would suck (if dosages were non-cosmetic) but whatever.

[youngin]

I'm actually pretty excited about this even if IGF-1 isn't effective. The fact that there's a new vehicle to deliver treatments in a way that hasn't been possible could be big if Promethon is potentially partnering with other companies. Waiting on clinical trials would suck (if dosages were non-cosmetic) but whatever.

Where is the proof that this delivery system only saturates the follicles and doesn't go systemic? I have seen none. We have had delivery systems for years that will go deeper than the follicle for several drugs. The problem is getting them to stay at the follicle only. I don't see how this fixes that, it only allows for larger molecules. Everyone is raving with no proof.

[gainspotter]

Why is nameless known as jarjarbinx? Just curious lol

[NeedHairASAP]

Where is the proof that this delivery system only saturates the follicles and doesn't go systemic? I have seen none. We have had delivery systems for years that will go deeper than the follicle for several drugs. The problem is getting them to stay at the follicle only. I don't see how this fixes that, it only allows for larger molecules. Everyone is raving with no proof.

I think it's not so much that the vehicle directs the drug to the follicle as it is the vehicle can get large molecules like igf-1 through the dermis.

Previously, you injected igf-1 and hoped it circulated around in the blood stream and eventually got to dermal papilla.

Now, we can apply igf-1 topically right near the dermal papilla. So it's more likely we get igf-1 into the dermal papilla.


Injections = Through Dermis ----> into blood stream ---> around body --> to DPs

Follicept vehicle = Through Dermis ---> to DP Cells


i.e.

injections = Elmer Fudd with birdshot in a shotgun

follicept = navy seal with finely tuned sniper rifle and cool sun glasses

(allegedly/hopefully)