OC info+ use RU at your own risk

[sdsurfin]

I'll use as much as I can based on price. Hopefully if it's not enough it'll at least slow loss.

[KO1]

If you are in contact with Kythera. Did Actelion notice effects on hair during their trial? It would be curious to know whySeti and not TM/OC

[HairlossAt15]

I have 10k put into Kythera stock, and I've been in contact with them numerous times. The trial will start the beginning of 2016, and then they will have to collect data and then publish it. End of 2017 at the soonest, 2018 more likely. I didn't realize you were a doctor or researcher who knew everything about the drug and how it will affect everyone's hair. Why don't you enlighten us?


Proscar was in almost the same situation before propecia was released, people jumped on it early because of factual evidence and saved their hair.

We are talking about oc and RU here?

[It's2014ComeOnAlready]

I have 10k put into Kythera stock, and I've been in contact with them numerous times. The trial will start the beginning of 2016, and then they will have to collect data and then publish it. End of 2017 at the soonest, 2018 more likely. I didn't realize you were a doctor or researcher who knew everything about the drug and how it will affect everyone's hair. Why don't you enlighten us?


Proscar was in almost the same situation before propecia was released, people jumped on it early because of factual evidence and saved their hair.

Well, as you said they plan on doing a POC and based on that (if results are positive) they will immediately jump into a phase 3. During a phase 3 they can apply for an NDA with the FDA and hopefully a commercial release. Based on that, we should expect this product at around 2-2.5 years. Hopefully as time goes by we can figure out a homemade formula with a pgd2 blocker and people can jump off the fin if they want.

Great investment BTW

[FearTheLoss]

sorry he hasn't priced OC yet. he priced setipiprant at 300 for 15 grams. my mistake. but OC will prob be similar or cheaper because it is not licensed in the US.

SD, I'm slightly worried that taking 500mg a day won't be enough, especially since it was trialled at 2g a day for asthma. Maybe if we order like 60g at a time, or we do a group buy we can get it down even cheaper.

What do you plan on taking a day? I'd like to be taking at least 1g. I'd even consider applying OC topically as well, as cots actually recommended that a topical PDG2 inhibitor was the best way to go.

[FearTheLoss]

More like late 2016, early 2017....not that long. We all know it is backed by cots work,but it is not as simple as buying the raw product and living happily ever after

I have 10k put into Kythera stock, and I've been in contact with them numerous times. The trial will start the beginning of 2016, and then they will have to collect data and then publish it. End of 2017 at the soonest, 2018 more likely. I didn't realize you were a doctor or researcher who knew everything about the drug and how it will affect everyone's hair. Why don't you enlighten us?


Proscar was in almost the same situation before propecia was released, people jumped on it early because of factual evidence and saved their hair.

[unbalding]

More like late 2016, early 2017....not that long. We all know it is backed by cots work,but it is not as simple as buying the raw product and living happily ever after

Maybe you want to wait around and lose a couple norwoods by then, but I don't.

[HairlossAt15]

Because we won't know results until 2018. Furthermore, it's backed by cots work and doesnt have a dangerous side effect profile

More like late 2016, early 2017....not that long. We all know it is backed by cots work,but it is not as simple as buying the raw product and living happily ever after

[unbalding]

sorry he hasn't priced OC yet. he priced setipiprant at 300 for 15 grams. my mistake. but OC will prob be similar or cheaper because it is not licensed in the US.

That's a good price. Did you ask him about TM30089 too? I am currently using ramatroban, which should have similar results to OC, and I am shedding about the same as when I was using RU(50-100 hairs/day). I'm hoping TM can dramatically reduce that number.

[sdsurfin]

sorry he hasn't priced OC yet. he priced setipiprant at 300 for 15 grams. my mistake. but OC will prob be similar or cheaper because it is not licensed in the US.

[FearTheLoss]

Best bet is to work with the other guy and not cane. He cut the price to a tenth of what kane advertised. Only question left is to figure out which compound makes the most sense. That TM drug is looking pretty good if it dissolves in water. Maybe trade off one day on that topically and one day on setipip orally. I have high hopes.

He cut OC to a tenth? $27 a gram? What did he say about setipiprant

[sdsurfin]

Best bet is to work with the other guy and not cane. He cut the price to a tenth of what kane advertised. Only question left is to figure out which compound makes the most sense. That TM drug is looking pretty good if it dissolves in water. Maybe trade off one day on that topically and one day on setipip orally. I have high hopes.

[FearTheLoss]

Best option is to wait for the poc trial to be completed with Kythera. Then we will have concrete data on humans seeing how effective gpr44 blockers really are. Will also know correct dosage, safety and health risks etc

Because we won't know results until 2018. Furthermore, it's backed by cots work and doesnt have a dangerous side effect profile

[Hairismylife]

Swooping why are you keep posting negative comments on Pgd2 when their is solid science behind? Seems you only support RU but RU should only be a bridge of time considering it's safety profile. I would definitely lower my RU dosage to 2% if I get OC.
Plus, we are seeking regrowth treatment and Bim seems able to do something. Most of us would be happy if itcdan bring us back 1 norwood.

[Illusion]

Just got this email from Anagen:

"dear friend,

Our Head Manufacture kane in china is still on holiday. back at 27-2.

re setipiprant, once they're back.

1). they'll check if this chemical is patented in china.
2). they'll check if chemical is licensed by any drug distributor.
3). As if its licensed they'll,contact the company for agreement to produce and sell this research chemical strictly as for research purpose not for human use.in small quantities. there is no guarantee for grand production right at high quantity if drugs is licensed already.
4). price for small scale production for research purpose only. won't be economical.


as for OC000459, oc000459-ethanol and TM , both very selective CRTH2 antagonists, please tell them the quantity you're interested in, they'll give a great discount for volume deal. We have both products are in stock.
You can arrange a group buy if there is interest. please let me know the total quantity."

Also sent a mail to Kane re: OC and sep and got exactly the same reply as the one quoted above.