2015- Make or Break Future Treatments

[Illusion]

Who knows how much time they will need? 5 years? 10 years? I certainly hope it's been done before 10 years.

Don't be delusional.

[bananana]

You know whats funny. When I first saw this website sometime in 2009, and I saw a guy with nickname "2020", I thought - we'd have teleporters by then, let alone full head of hair. Now not even 2020 looks realistic.

All jokes aside, I'm really glad there is some great progress lately with understanding MPB, and that is 80% of work, right there. So, high hopes for 2020!
(and 2015 )

[burtandernie]

Are any other countries going to approve CB for hair loss before the US that you could just buy from there instead sooner? Getting the chemical from a real certified manufacturer is the hard part.

[Notcoolanymore]

Are any other countries going to approve CB for hair loss before the US that you could just buy from there instead sooner? Getting the chemical from a real certified manufacturer is the hard part.

Isn't hellouser already using this shit?

[hellouser]

Isn't hellouser already using this shit?

I'm not the only one...

[DepressedByHairLoss]

You know whats funny. When I first saw this website sometime in 2009, and I saw a guy with nickname "2020", I thought - we'd have teleporters by then, let alone full head of hair. Now not even 2020 looks realistic.

All jokes aside, I'm really glad there is some great progress lately with understanding MPB, and that is 80% of work, right there. So, high hopes for 2020!
(and 2015 )

It doesn't really surprise me at all because barely anyone is even TRYING to cure baldness? All we hear about is "hair transplant this and hair transplant that" with absolutely no commitment to innovation to trying to find a treatment that actually serves more than a small sliver of hair loss community.

[hellouser]

It doesn't really surprise me at all because barely anyone is even TRYING to cure baldness? All we hear about is "hair transplant this and hair transplant that" with absolutely no commitment to innovation to trying to find a treatment that actually serves more than a small sliver of hair loss community.

If I said this, I'd get chastised. But you're on the money... there's... what, 3 or 4 teams working on a solution? That's crap. Every few weeks there's a new paper published... and all of them on mice, but never a single case study on ONE human. WTF???

[Hairismylife]

I'm not the only one...

Any result????
I think RU gives me a little bit side on my dick, but tolerable.

[jacobus]

I'm not the only one...

Could you please share your experience with it? I've read almost every single post on CB-01-03 on the forums here, but understood that (at the moment) CB-01-03 was unusable as it needed a 'wetting agent' in addition to VERSAPRO. I noticed that you dismissed your 7-month trial (as the vehicle probably was not working), is this time different?

PS: Sorry for my English and lack of posts (usually on the Dutch forums).

[brocktherock]

[QUOTE=hellouser;194942]If I said this, I'd get chastised. But you're on the money... there's... what, 3 or 4 teams working on a solution? That's crap. Every few weeks there's a new paper published... and all of them on mice, but never a single case study on ONE human. WTF???[/QUOTE
There is a lot of money being thrown at it though. I started on these forums in mid 2012 and I wasn't sure if I'd live to see a cure. Now Im confident we will have a cure or something damn close within 5 years (I know, 5 years away hahaha). Hellouser, you gotta admit that we are on the verge of seeing big things. Plus these new laws in japan has been a huge step forward for all fields of medicine.

[Trenblastoise]

I have the most confidence in stem cell research. I don't care about pills that mess up hormone levels or give you temporarily results, I care about an actual cure. And this is a field that can cure it.

The first step:
They have managed to convert human skin cells into induced pluripotent stem cells (iPSCs) by adding three genes, these can change into any cell types in the body.

The Second step:
I'd say is to create the complete follicles.
So far they haven't managed to create all the different cells to do this, tho they have managed to create epithelial stem cells, which are found in part of hair follicles.
They have also managed to turn the iPSC into keratinocytes, which is the main cells in the top layer of the skin.

The Third step:
They haven't figured to make dermal papillae, which is the second type of cells part of the hair follicle as far as I understood Dr. Xu.

The Fourth step:
Successfully carry it out in practice.

If anyone got more information on this, please link me to it, I'd like to read it to understand the position better. Who knows how much time they will need? 5 years? 10 years? I certainly hope it's been done before 10 years. In the meantime I suppose I should continue looking into FUE transplant so I got something in the gap. My hair loss is rather slow, I think FUE can help me out for 10-15 years.

Just quoting my own post, as it is too late for me to edit it. I suppose I should left my optimism out of it.

However, I figured out that they have managed to make Dermal Papillae cells - tho it is not from skin cells, but from copying existing dermal Papillae. I read upon one study where they had managed to copy thousands. As Arashi pointed out; They haven't worked out everything just yet. The Dermal Papillae cells they copy are inconsistent in quality.

I really do not think this will take 35 years to figure out. That remains to see, given I still consider myself ignorant on this field it seems to be that most of the ground work is already done. Stem Cell research from other branches can also effect.

I'll continue to read on this, it's exciting

[Tenma]

But if you're specifically interested in the iPSC route -> yeah they need to figure out how to induce iPSC cells to become DP cells.

Well, a very fresh study published 21/1 showed for the first time that it is possible to obtain dp cells from pluripotent cells:

http://www.ncbi.nlm.nih.gov/pubmed/25607935

Very exciting news!

[Trenblastoise]

Well, a very fresh study published 21/1 showed for the first time that it is possible to obtain dp cells from pluripotent cells:

http://www.ncbi.nlm.nih.gov/pubmed/25607935

Very exciting news!

I also read we can copy dp cells thousands of times with dp cells. However not all of them are perfectly function-able.

[balding1983]

This thread made me laugh!
Brief history lesson:
Only two effective treatments so far are Minoxidil and Finasteride.
Minoxidil was discovered by accident by doctors who were using Minoxidil to treat hypertension.
Finasteride was discovered by accident in the process of treating BPH.

Possible future treatments:
Bimatoprost was discovered accidentally through the treatment of glaucoma. Even after its discovery the pharma companies thought it was more important for women to have longer, fuller eye lashes. That in itself shows how little regard they have for MPB sufferers.

What you need to understand is that MPB research doesn't exactly attract the cream of the crop of medical researchers. The talented ones will be drawn to other more academically fulfilling fields, eg. Cancer.

Seriously, what have the 'researchers' who are only concerned with MPB achieved in terms of bringing anything viable to the market with decades of study - Nothing!

People shouldn't be waiting for the MPB researchers to have a break through but instead they should be praying that some doctor or researcher working in another field stumbles onto something relevant. These guys are our only hope.

Rant over!

[Trenblastoise]

I am glad the thread made you laugh balding1983.

I don't think the way to go is through drugs at all. And what matters is for those that do care about them that they get discovered, not how. And that they do get tested.

I am surprised you don't mention stem cell as possible future treatments, tho it will not be ready this year, or the next. It is the most promising field and a lot of research is put into it. Most of the resources are not to make hair, but it is stem cell research never the less and it has been moving forward quicker and quicker.

It goes disappointing slow, or it has over the decades. I haven't felt that too much myself as I am quite young and with rather slow receding. I just hope they continue to make breakthroughs with stem cells and that it will be complete or near completion in ~15 years tops.