Article on piloscopy...

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  • Trenblastoise
    Senior Member
    • Jul 2014
    • 142

    Originally posted by Hairismylife
    Donor regeneration is one of the advantage of Pilofocus we concern.
    Scarless is indeed a big step forward tho.
    Okay. I'll believe it when I get it demonstrated before me. It sounds extraordinary that you can take out all the dermal papilla, move it somewhere else to plant, and then the body will create new dermal papilla by itself in the spot you took it from.


    I am aware some FuE has regeneration, and I suggest a lot of this is caused by actually missing the follicle and taking half of it, or at least enough dermal papilla to create hair. I haven't been presented with any evidence of regeneration in a spot where all the dermal papilla got taken out, it sounds extraordinary, but when if it gets demonstrated that is good news for us.

    I'll in the meantime doubt it and hope the procedure will be scar less without causing significant nerve damage or a higher chance of infections.

    Comment

    • Hairismylife
      Senior Member
      • Jun 2012
      • 383

      Originally posted by Trenblastoise
      Okay. I'll believe it when I get it demonstrated before me. It sounds extraordinary that you can take out all the dermal papilla, move it somewhere else to plant, and then the body will create new dermal papilla by itself in the spot you took it from.


      I am aware some FuE has regeneration, and I suggest a lot of this is caused by actually missing the follicle and taking half of it, or at least enough dermal papilla to create hair. I haven't been presented with any evidence of regeneration in a spot where all the dermal papilla got taken out, it sounds extraordinary, but when if it gets demonstrated that is good news for us.

      I'll in the meantime doubt it and hope the procedure will be scar less without causing significant nerve damage or a higher chance of infections.
      And a higher survival rate as well.

      Comment

      • FearTheLoss
        Senior Member
        • Dec 2012
        • 1581

        Originally posted by Trenblastoise
        Okay. I'll believe it when I get it demonstrated before me. It sounds extraordinary that you can take out all the dermal papilla, move it somewhere else to plant, and then the body will create new dermal papilla by itself in the spot you took it from.


        I am aware some FuE has regeneration, and I suggest a lot of this is caused by actually missing the follicle and taking half of it, or at least enough dermal papilla to create hair. I haven't been presented with any evidence of regeneration in a spot where all the dermal papilla got taken out, it sounds extraordinary, but when if it gets demonstrated that is good news for us.

        I'll in the meantime doubt it and hope the procedure will be scar less without causing significant nerve damage or a higher chance of infections.
        Duplicative surgery might represent a successful alternative for hair transplantation, because both portions are capable of regenerating a healthy hair. Moreover, our results suggest the possible presence of stem cells in both halves of the follicle.

        Comment

        • Trenblastoise
          Senior Member
          • Jul 2014
          • 142

          Originally posted by Hairismylife
          And a higher survival rate as well.
          Yes, and I suspect if will have very marginally better than FuT as well (some follicles on the edges will probably be damaged), and significantly better than FuE.

          Originally posted by FearTheLoss
          The study you proved states what I thought. I quote from the abstract:

          "BACKGROUND:

          The use of bisected hair follicles in hair transplantation has been previously reported, but the capacity of each half to regenerate the entire hair has not been clarified."

          Piloscopy does not bisect hair follicles, it captures the entire hair follicle, with some surrounding protective tissue. Based on this, I am not convinced there will be any regeneration will occur in the donor area, as all of the dermal papilla will be taken with some surrounding protective tissue.


          I would also like to note, that I think I read some other users study on hair follicle that the hair becomes greater propositional to the active dermal papilla. That is. if you do bisect the hair follicle, those two will individually produce weaker hairs than a full follicle. Your article states that the bisected hair follicles grow equal to each other, unless I misread it. thanks for the info however

          Comment

          • FearTheLoss
            Senior Member
            • Dec 2012
            • 1581

            Think outside the box for a second. If you are coming up from below, you can capture the whole follicle and surrounding tissue. However, like this study states, if you bisect the follicle HORIZONTALLY, both halves are capable of producing a hair. So, if you adjust the depth the follicle is cut off at, you'd essentially be "halving" the follicle during extraction.

            In this study, they bisected the follicles horizontally and got 70%+ growth from each half when reimplanted.

            Comment

            • Trenblastoise
              Senior Member
              • Jul 2014
              • 142

              Originally posted by FearTheLoss
              Think outside the box for a second. If you are coming up from below, you can capture the whole follicle and surrounding tissue. However, like this study states, if you bisect the follicle HORIZONTALLY, both halves are capable of producing a hair. So, if you adjust the depth the follicle is cut off at, you'd essentially be "halving" the follicle during extraction.

              In this study, they bisected the follicles horizontally and got 70%+ growth from each half when reimplanted.
              Okay, you want to bisect the follicles with the method. And there is evidence suggesting it can result in two follicles growing at ~70%. I wonder if this will make the hair follicle degenerate quicker, do you know?

              Comment

              • FearTheLoss
                Senior Member
                • Dec 2012
                • 1581

                Originally posted by Trenblastoise
                Okay, you want to bisect the follicles with the method. And there is evidence suggesting it can result in two follicles growing at ~70%. I wonder if this will make the hair follicle degenerate quicker, do you know?
                I don't see why it would. My understanding is, with this method, in the study, they bisected the follicle under a microscope and implanted both halves into a balding area of the scalp and still got 70%+ growth in both halves. However, Dr. Wesley's method, in theory, would be superior to the method used in the study as one half of the follicle would be staying in its original environment surrounded with fatty tissue and growth factors.

                Comment

                • hairy
                  Member
                  • Jun 2011
                  • 63

                  What part of the video does he discuss regeneration?

                  Comment

                  • Artista
                    Senior Member
                    • Apr 2010
                    • 2070

                    Hello everyone!!

                    My wife and I had recently arrived back home from our vacation out in Manhattan, NYC.

                    Our meeting with Dr. Wesley (at the upper east side of Manhattan) was a very good meeting!
                    We finally had a conversation in person and it was very positive!!
                    Dr. Wesley will be restarting his Phase-Testing POSSIBLY at the 1st or second week of this coming May 2015.
                    Now keep in mind that the restart time-frame I mentioned isn't 'written in stone' as yet.
                    As I have said many times before, He is a VERY BUSY Doctor. SINCERE in what he is doing as well.

                    Dr. Wesley did of course medically review my hair.
                    He said that my donor hair area is in superb shape and very full, very healthy.
                    So it has now been confirmed/verified that I am definitely a patient of his Phase-Testing (later on in the testing)
                    It will be an exciting time once I am scheduled.

                    I have no problem with the waiting time.
                    After all , Finasteride has been doing a good job at improving my hairs density by decent percentages.

                    We LOVED our Manhattan vacation!

                    Comment

                    • Hairismylife
                      Senior Member
                      • Jun 2012
                      • 383

                      Originally posted by Artista
                      Hello everyone!!

                      My wife and I had recently arrived back home from our vacation out in Manhattan, NYC.

                      Our meeting with Dr. Wesley (at the upper east side of Manhattan) was a very good meeting!
                      We finally had a conversation in person and it was very positive!!
                      Dr. Wesley will be restarting his Phase-Testing POSSIBLY at the 1st or second week of this coming May 2015.
                      Now keep in mind that the restart time-frame I mentioned isn't 'written in stone' as yet.
                      As I have said many times before, He is a VERY BUSY Doctor. SINCERE in what he is doing as well.

                      Dr. Wesley did of course medically review my hair.
                      He said that my donor hair area is in superb shape and very full, very healthy.
                      So it has now been confirmed/verified that I am definitely a patient of his Phase-Testing (later on in the testing)
                      It will be an exciting time once I am scheduled.

                      I have no problem with the waiting time.
                      After all , Finasteride has been doing a good job at improving my hairs density by decent percentages.

                      We LOVED our Manhattan vacation!
                      Nohing exciting if he doesnt has confidence in donor regeneration.

                      Comment

                      • tedwuji
                        Senior Member
                        • Jun 2014
                        • 474

                        Originally posted by Artista
                        Hello everyone!!

                        My wife and I had recently arrived back home from our vacation out in Manhattan, NYC.

                        Our meeting with Dr. Wesley (at the upper east side of Manhattan) was a very good meeting!
                        We finally had a conversation in person and it was very positive!!
                        Dr. Wesley will be restarting his Phase-Testing POSSIBLY at the 1st or second week of this coming May 2015.
                        Now keep in mind that the restart time-frame I mentioned isn't 'written in stone' as yet.
                        As I have said many times before, He is a VERY BUSY Doctor. SINCERE in what he is doing as well.

                        Dr. Wesley did of course medically review my hair.
                        He said that my donor hair area is in superb shape and very full, very healthy.
                        So it has now been confirmed/verified that I am definitely a patient of his Phase-Testing (later on in the testing)
                        It will be an exciting time once I am scheduled.

                        I have no problem with the waiting time.
                        After all , Finasteride has been doing a good job at improving my hairs density by decent percentages.

                        We LOVED our Manhattan vacation!
                        We knew you were gonna be a patient already. Can you talk more about the phase-testing? when will you be a patient? what are the details with this? do you need to take time off of work?

                        Comment

                        • Trenblastoise
                          Senior Member
                          • Jul 2014
                          • 142

                          Originally posted by Hairismylife
                          Nohing exciting if he doesnt has confidence in donor regeneration.
                          I'd still have this over FuE, assuming equal quality doctors, as piloscopy will be quicker and leave no scars other than a half an inch one. Tho, it doubt this method will be widely out and perfected by skilled doctors any time soon, maybe 5 years or 10 years :/

                          Time will tell. Donor regeneration would be something I guess.

                          Comment

                          • FearTheLoss
                            Senior Member
                            • Dec 2012
                            • 1581

                            Originally posted by Hairismylife
                            Nohing exciting if he doesnt has confidence in donor regeneration.
                            Dr. Wesley does have confidence in donor regeneration. However, you all have to realize these things don't happen over night. Dr. Wesley is not purposely delaying the progression and commercialization of pilofocus to spite you, I can promise you that.

                            Furthermore, while Dr. Wesley has said he believes in the regeneration aspect and has confidence in it, he's not going to start promising things he isn't 100% sure about (like some doctors do). Let him do his work, stay positive and wait for him to provide more clear evidence for his instrument's benefits like he has thus far.

                            Good to hear your trip to NYC was fun Artista!

                            Comment

                            • Artista
                              Senior Member
                              • Apr 2010
                              • 2070

                              First of all thank you Fear'!
                              We certainly did have a good time out there....
                              To everyone else,
                              FearTheLoss' response just now was so true!
                              He explained perfectly how the basic process is going via a very sincere Dr Wesley ...
                              We all must be patient on this.

                              Comment

                              • Javert
                                Member
                                • Jun 2013
                                • 99

                                Originally posted by Artista
                                First of all thank you Fear'!
                                We certainly did have a good time out there....
                                To everyone else,
                                FearTheLoss' response just now was so true!
                                He explained perfectly how the basic process is going via a very sincere Dr Wesley ...
                                We all must be patient on this.

                                Comment

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