Dr Lauster's Team (Berlin University of Technology)

[Swooping]

Well let's look at the facts:

Replicel began their Phase I clinical trials not that long ago, essentially in 2011. They stalled for about a year or so and they may go commercial in 2016 thanks to Japan's the new legislation. That's a 5 year span WITH slacking. It would be pretty ridiculous to say 'there's no chance in hell Dr. Lauster's team is going to match that.' Of course they can. It's being done RIGHT NOW. Aderan's took forever... but I blame that largely on incompetence with finding investors. Imagine, we could have had a legit treatment that at least permanently stops further hair loss with better results than finasteride/minox albeit not full reversal. I'd pay for that.

Fingers crossed for speedy trials with both Lauster and Replicel. I do wonder what that team in Taiwan is doing with the 400 man trials and DP cells.

Forget about replicel dude. They only use DSC cells right?

:")... Ask Alvi Armani why he stopped research. Not only did he try DSC cells but also ORS, EMS and DPC. Yes, he did that + injected it in human subjects. Something like replicel albeit minor beneficial will never be a permanent solution too. Give him a call he'll explain you why he ceased research.

[hellouser]

Forget about replicel dude. They only use DSC cells right?

:")... Ask Alvi Armani why he stopped research. Not only did he try DSC cells but also ORS, EMS and DPC. Yes, he did that + injected it in human subjects. Something like replicel albeit minor beneficial will never be a permanent solution too. Give him a call he'll explain you why he ceased research.

I put Alvi Armani in the same category as Craig Zeiring. I wouldn't take him too seriously.

[efedrez]

Forget about replicel dude. They only use DSC cells right?

:")... Ask Alvi Armani why he stopped research. Not only did he try DSC cells but also ORS, EMS and DPC. Yes, he did that + injected it in human subjects. Something like replicel albeit minor beneficial will never be a permanent solution too. Give him a call he'll explain you why he ceased research.

I find hard to believe that a company like Shiseido is backing up a dead end research

For sure cracking this is is complicated and someone like Armany might have ran out of ideas and founds pretty quickly but I'm very optimistic, yet realistic, about Replicel

[Swooping]

I find hard to believe that a company like Shiseido is backing up a dead end research

For sure cracking this is is complicated and someone like Armany might have ran out of ideas and founds pretty quickly but I'm very optimistic, yet realistic, about Replicel

Well, yes maybe it depends on their method. Does anyone know what (new) patent is related to these clinical trials? Is it this one; https://www.google.com/patents/EP2623106A1?cl=en ?? Thanks!

[sdsurfin]

Do you have any other inside information you'd like to share? You seem to have all the answers.

Don't really have any answers, just guesses like everyone else, and knowledge of how long these things take.

I think Lauster's team and others like Tsuji labs are working on some really revolutionary stuff, way more groundbreaking and leaps ahead of anything done in medicine let alone hair loss research. Making new organs can and will be the solution to a lot of issues, and I find it pretty remarkable that we get to see at least the start of it. If it's true that they are planning trials then that's awesome, but they said that a few years ago too. The presentations that desmond showed us didn't give any indication that they are close to trialling a real treatment, but I would be surprised if some kind of injectable follicle booster doesnt pan out within the next 8 yrs or so, which is cool. I think replicel is on track to be marketed, financially and resource-wise, I don't see shiseido just giving up, if it doesnt work i would imagine they would keep researching stem cells and growth factors until they got something useable. Aderans may have failed but they were still a stepping stone.

Realistically I just want a treatment that is as good as propecia but safer, and hopefully that will come in the not too distant future. finasteride already makes balding a moot point for most of the guys who can tolerate it, which is pretty miraculous. Just want something as decent. and I'm happy to see where stem cell stuff goes, but not under any illusions that it'll pan out into a miracle cure while i'm still young.

[nameless]

I don't get how they can even be considering trials when there's still so much work left to be done.

+1

The German team is hoping that they're follicles are ready, but I don't think that they have total confidence. I think they know there are issues that should be resolved before starting trials, but they are hoping that if they implant their lab-grown follicles into human scalps the implanted follicles will signal the skin to make necessary skin adjustments in order to work with the follicles.

Could that happen? Yes. Will it? I don't know. If it doesn't happen then they will learn that they have to prepare the skin before implanting their lab-grown follicles, and they will try again after prepping the scalp skin.

[sascha]

Don't really have any answers, just guesses like everyone else, and knowledge of how long these things take.

I think Lauster's team and others like Tsuji labs are working on some really revolutionary stuff, way more groundbreaking and leaps ahead of anything done in medicine let alone hair loss research. Making new organs can and will be the solution to a lot of issues, and I find it pretty remarkable that we get to see at least the start of it. If it's true that they are planning trials then that's awesome, but they said that a few years ago too. The presentations that desmond showed us didn't give any indication that they are close to trialling a real treatment, but I would be surprised if some kind of injectable follicle booster doesnt pan out within the next 8 yrs or so, which is cool. I think replicel is on track to be marketed, financially and resource-wise, I don't see shiseido just giving up, if it doesnt work i would imagine they would keep researching stem cells and growth factors until they got something useable. Aderans may have failed but they were still a stepping stone.

Realistically I just want a treatment that is as good as propecia but safer, and hopefully that will come in the not too distant future. finasteride already makes balding a moot point for most of the guys who can tolerate it, which is pretty miraculous. Just want something as decent. and I'm happy to see where stem cell stuff goes, but not under any illusions that it'll pan out into a miracle cure while i'm still young.

We are not talking about the cure. We talk about the treatment the germans will bring to market, or Replicel/Shiseido will bring to market and they already showed some kind of results, so do not dare to tell people that under the right circumstances this stuff can't work. The degree is not that important for the moment. I bet you anything you want that the more they try on real patients under real circumstances the faster this technologies will advance.
Enough with all the negativity. And for your case: Are you that sceptical about CB 03 01 and PGD2 blockers? sorry if off-topic

[Jasari]

Realistically I just want a treatment that is as good as propecia but safer, and hopefully that will come in the not too distant future. finasteride already makes balding a moot point for most of the guys who can tolerate it, which is pretty miraculous.

What sort of Fin do you use? I get zero sides [That I'm aware of] but it only marginally slows the loss. Of all the years I've been on various forums I haven't seen too many success stories [And I deem success as maintenance].

[stan]

What sort of Fin do you use? I get zero sides [That I'm aware of] but it only marginally slows the loss. Of all the years I've been on various forums I haven't seen too many success stories [And I deem success as maintenance].

Well because not everybody is gonna report to you if they get success.

[Tenma]

What sort of Fin do you use? I get zero sides [That I'm aware of] but it only marginally slows the loss. Of all the years I've been on various forums I haven't seen too many success stories [And I deem success as maintenance].

http://www.bernsteinmedical.com/research/10-year-finasteride-study-first-to-investigate-long-term-effects-and-safety/

This study confirms that fin works very well for maintenance.

More than 90% were at or above baseline after 10 years

[JZA70]

This study confirms that fin works very well for maintenance.

More than 90% were at or above baseline after 10 years

So does castration, doesn't mean it's a viable option.

[sdsurfin]

What sort of Fin do you use? I get zero sides [That I'm aware of] but it only marginally slows the loss. Of all the years I've been on various forums I haven't seen too many success stories [And I deem success as maintenance].

I don't use fin due to sides. But I know guys who have held onto their hair for a long time on it. I even know guys who stopped balding for years just on minox. I think the forums prob give you a skewed perspective, the guys who have success on these drugs aren't looking for other answers.

If fin really doesn't due much but slightly slow balding, then CB isn't going to be much better. I'm hoping a combination of something like CB and something like replicel will be a good ticket in the next decade though. Complete stem cell regeneration of full baldness will be incredible but is very far off in terms of mareketable cosmetics even though the science is at the doorstep.

[nameless]

This thread started out as a discussion about the German team and their bio-reactor hair follicles and now it has morphed into a conversation about minoxidil and propecia. What a disaster.

Can we please get back on point?

[Jasari]

I don't use fin due to sides. But I know guys who have held onto their hair for a long time on it. I even know guys who stopped balding for years just on minox. I think the forums prob give you a skewed perspective, the guys who have success on these drugs aren't looking for other answers.

If fin really doesn't due much but slightly slow balding, then CB isn't going to be much better. I'm hoping a combination of something like CB and something like replicel will be a good ticket in the next decade though. Complete stem cell regeneration of full baldness will be incredible but is very far off in terms of mareketable cosmetics even though the science is at the doorstep.

In my experience the fin/minox combo I've been on for the past five years slows the loss - but you still progress down the Norwood scale [If you are destined to do so].

Hopefully something comes out in the future which provides regrowth; but if they do get something that guarantees safe maintenance that will essentially be a cure.

Every person would just pop a pill the moment hair loss appears. From a business perspective; if something like that existed would there really be any value in a regrowth treatment? This generation & up would be the last people to suffer the problem & that doesn't ensure any long term profits.

[Jasari]

Well because not everybody is gonna report to you if they get success.

No need to be a troll.

If Fin guaranteed maintenance you would only have two camps:
- People that don't suffer hair loss due to fin.
- And the rest i.e: I'm losing my hair because I can't/won't take fin.

The reality is that fin works for small percentage of people. Something that guarantees maintenance is a cure.