adipose-derived stem cell protein extract

[moleular]

With regard to adipose extraction method, it isn't a straightforward process.
It will be something like the following;

http://www.adistem.com/technology/adipose-derived-adult-stem-cells/

It seems adistem have chosen to use PRP as the sort of 'carrier'. I don't know whether they use that at the clinic, but it would need some sort of liquid carrier to make the most of the harvested stem cells from the adipose tissue, and probably simply provide enough liquid for injection.

Interestingly, when PRP comes into contact with collagen, it is then activated and the growth factors present within it, increase in their potency.
This is a good and bad thing, as TGF-ß1 is also increased, which is in fact a hinderer of hair growth. It's part of the reason why standard PRP isn't very effective when injected standalone.
Using ACell or other extracellular matrix helps to combat this to some degree by giving the stem cells present in the plasma a scaffold to grow.

I should also note this isn't something you'd want to do at home. I have actually tried to inject things into my scalp and it hurts A LOT.
Typically such therapies are provided using mesotherapy techniques such as nappage or other shallow intradermal injections.
It takes a little skill to get it down properly.

[bananana]

Great man. What is their method then? They extract it, seperate it and immediately inject it or what? Btw, how hard is it do yourself? Is there anyone here with lab experience, obviously you would need the equipment etc. But seems like it is rather easy? 5000 euro is alot, very curious what it will cost through this swiss lab.

Yeah.
5k euro is a huge price, how long can there results last?

[Swooping]

http://ddrheinrich.com/en/treatments...ir/stem-cells/

I've been in contact with them. They offer ADSC's and their respective growth factors.
They aren't cultured in hypoxic conditions, as they were in the research at the start of this thread.
Culturing stem cells for therapy (according to them) is currently not allowed under EU law, although they have mentioned that it is possible via their Swiss lab.
Their basic ADSC procedure is €5000.
I'm awaiting some answers to various things, but will keep you posted.

Great man. What is their method then? They extract it, seperate it and immediately inject it or what? Btw, how hard is it do yourself? Is there anyone here with lab experience, obviously you would need the equipment etc. But seems like it is rather easy? 5000 euro is alot, very curious what it will cost through this swiss lab.

[nliyan25]

good point

I saw it and contacted the guy.
He offered very little information in response to my questions, and pointed me to a really poor wix site for answers.
I should imagine it's either not the real thing, or he gets it through back door channels.
Having bought real growth factors from life science companies, I know that they can't just be kept refrigerated as he suggested, and if they are, they need to be used rapidly to maintain a biological response. They also need to be shipped in icepacks and with a rapid shipping service.

Having said that, I think it needs probing more, and really pin him down on the source. It could well come from the korean company which make it, but he's probably going to be reluctant to say much, given that it won't be fda approved

Good point, let's hope it's the real thing.

[moleular]

I saw it and contacted the guy.
He offered very little information in response to my questions, and pointed me to a really poor wix site for answers.
I should imagine it's either not the real thing, or he gets it through back door channels.
Having bought real growth factors from life science companies, I know that they can't just be kept refrigerated as he suggested, and if they are, they need to be used rapidly to maintain a biological response. They also need to be shipped in icepacks and with a rapid shipping service.

Having said that, I think it needs probing more, and really pin him down on the source. It could well come from the korean company which make it, but he's probably going to be reluctant to say much, given that it won't be fda approved