adipose-derived stem cell protein extract

[hellouser]

Pls elaborate with details? I was unaware that he has done things to garner a reputation like this.

He's on television selling all sorts of crappy treatments. Even tried to sell the laser helmet;

https://www.youtube.com/watch?v=CQF8--8hRTo

You'd never see Dr. Jahoda, Lauster, Cotsarelis or Christiano selling this kind of shit.

Also, why does Spencer vouch for him then ?

$$$$$$$$$$$$$$$$$$$

[hgs1989]

Intresting

http://www.ncbi.nlm.nih.gov/pubmed/20956069

Application of mesenchymal stem cells(MSC) derived from bone marrow and umbilical cord in human hair multiplication.

they took MSC cultured then in a special medium (hydrocortisone and HGF) and injected them in mice and the result is that they induced hair follicle formation on nued mice. keep in mind that MSC can also be obtained from fat tissue (another name is adipose derived stem cells). opens the Idea of hair growth and new hair formation if Fat stem cells combined with prp and hydrocortisone(already used for Alopecia areata) rather than Acell+prp. since it can be done using the patient's own cells , it is achievable now.
Alias123 if you are going for your next treatment , you can combine both.

[nameless]

I believe that Ziering UK have been conducting clinical trials on Adipose stem cell this year, and are looking to start providing this treatment following a successful trial.

Could you please provide a source to prove this?

[hellouser]

http://www.ncbi.nlm.nih.gov/pubmed/20956069

Application of mesenchymal stem cells(MSC) derived from bone marrow and umbilical cord in human hair multiplication.

they took MSC cultured then in a special medium (hydrocortisone and HGF) and injected them in mice and the result is that they induced hair follicle formation on nued mice. keep in mind that MSC can also be obtained from fat tissue (another name is adipose derived stem cells). opens the Idea of hair growth and new hair formation if Fat stem cells combined with prp and hydrocortisone(already used for Alopecia areata) rather than Acell+prp. since it can be done using the patient's own cells , it is achievable now.
Alias123 if you are going for your next treatment , you can combine both.

That study was done on mice.

Would be nice if these 'compassionate' researchers did something meaningful... you know, like do research on humans rather than ****ing mice?

[nameless]

I have a phone consultation scheduled tomorrow with the clinic in Greece, anyone have any questions you want me to ask?

Alias I have questions for you to ask but I can't figure out who you're going to see. You said there were two clinics. You said one is in Vienna and the other is Swiss. Now you're saying the one is in Greece. So it looks like maybe now you are talking about 3 clinics (one is Vienna, one in Greece, and one in Switzerland) but I can't tell. You're not making your statements clear.

Is the ARS clinic and the Dr. Heinrich clinic the same clinic or are they different?

At the top of the ARS website it says they are in Switzerland. Are you saying that they aren't really in Switzerland?

Could you please clear some things up because you appear to be talking about 3 different clinics (Switzerland, Vienna, and Greece), and the different clinics have different names (ARS clinic & Dr. Heinrich clinic) but you also say they are both the same clinic just in different locations. If they're both Dr. Heinrich clinics then why are you saying that one of the clinics is called ARS? If they're both Dr. Heinrich clinics then they should both be called Dr. Heinrich clinics.

Would you please stop and think before you post and clear up where these clinics are and the names of the clinic.

[nameless]

Just to Make things clear with laws etc, the Swiss clinic you are all talking about is located in Greece, not Switzerland

Why are you saying that the Swiss clinic is in Greece? Are you saying that there is no ADSC clinic in Switzerland?

[hairandthere]

I don't take Zeiring seriously at all. This dude has his name slapped on every hair treatment known to man. Nothing he's done has been better than a simple stone aged hair transplant.

Are you implying that he lied about testing Histogen on humans? AFAIK, he claimed this on the show with Spencer and said that he hoped to be able to share some results in the future.

While a lot of the stuff you say is accurate, some of it is emotional and truth gets lost when that happens.

Let's try to stay positive and constructive.

As Wu-Tang puts it, C.R.E.A.M. In the end, money rules all and there are huge profits to be made in hairloss. If a treatment existed with the confidence that it would provide a good ROI, you can bet your ass it would be fast-tracked by those with the money and the connections! We're only getting closer...

[Jasari]

Pls elaborate with details? I was unaware that he has done things to garner a reputation like this.

Also, why does Spencer vouch for him then ?

I don't extensively know all the ins & outs of the hair loss industry but I've been on & off these boards for the better part of 5-6 years & I've even noticed Zeiring advertising/supporting some bogus bs.

I've also got the impression that Spencer is more about money than progress, especially after listening to a few radio podcasts.

[nameless]

you are right. I personally asked Dr.Gardner about the use of Gf for hair and he said they would work but stability and adjacent cells effects might be a concern.

HGS1989 check this out: since Jahoda is now using a construct that let's him add these same adipose derived stem cells to DP cells to create and enlarge follicles this means that if we get these adipose derived stem cells injections (Swiss clinic or greece clinic or Vienna clinic) we would be doing the same thing that Jahoda is doing, except that we would be doing it in our scalps whereas Jahoda is doing it in a petri-dish.

Let me say it again. Check this out:

* Jahoda is adding these cells to dp cells so he can grow and enlarge follicles.

* We would be putting these cells into our scalps to enlarge the existing follicles that are already in our scalps.

* This means we would be doing the same thing that Jahoda is doing except we would be doing it in the skin of our scalps instead of inside a petri-dish.



Also, an important note is that the Yale scientists discovered that the adipose precursor cells excrete 100 times as much of some growth factors as regular fat cells excrete. By injecting pure precursor cells (adipose derived stem cells) you are injecting 100 times more growth factors as you would if you just injected regular fat cells. So the key to this is to add the precursor fat cells, aka adipose derived stem cells so that you can bomb the follicles with the growth factors.

[hgs1989]

That study was done on mice.

Would be nice if these 'compassionate' researchers did something meaningful... you know, like do research on humans rather than ****ing mice?

yes but the hair was a human one. every thing was derived from human source and implanted on a nude mouse.

[nameless]

Dr. Gardner works for Dr. Jahoda. Dr. Gardner explained to us the following:

* Jahoda is now starting to add ADSCs to his cell culturing with hair cells so that the growth factors in ADSC will help the follicles form and enlarge.

Now think about this:

* The Swiss company is adding ADSCs to our hair cells so in our scalps and to the follicles in our scalps so that the growth factors in ADSC will help new follicles form and enlarge the already existing follicles in our scalps.

If you stop to think about it what the Swiss are doing, adding these adipose derived stem cells to our scalps, is the same thing that Jahoda is doing except that Jahoda is doing it in a petri-dish whereas the Swiss would do it in our scalps. The Swiss are bypassing the need to create follicles in a pertri-dish outside the person's body.

And Jahoda's petri-dish method is going to be way more complicated and way more expensive because you are having to create follicles in a petri-dish whereas the Swiss way utilizes the follicles that are already present in your own scalp. And in Jahoda's petri-dish method you would have to rely on the artistry of the doctor who implants the petri-dish follicles into your scalp. If you do it the Swiss way instead then the already existing follicles in your scalp could enlarge and they would probably articulate (grow outward) the same way they did naturally before hair loss started.

[hgs1989]

yes but the hair was a human one. every thing was derived from human source and implanted on a nude mouse.

the good news about ADSC is that replicel posted awhile ago about the fda speeding the approval process. http://blogs.fda.gov/fdavoice/index....cine-products/

[Alias123]

Why are you saying that the Swiss clinic is in Greece? Are you saying that there is no ADSC clinic in Switzerland?

yes thats what im saying. the reason people confuse it with a swiss clinic is because the swiss clinic have a collabration with a greek clinic ( might be same owner, same ethics etc, ) but the treatment itself is in greece.

[zeos]

don't think so,
i have just found a clinic in athens which is offering the ADSC treatment(maybe this is an annex of the Swiss clinic in athens-we have to find this out)and collaborates with that laboratory(http://theracell.eu/)

we should contact theracell to get all the addresses of clinics where we can get this treatment
with which clinic are you in contact?

it's translated from greek to english(from a medical site) but i think it's understandable
what are your thoughts?


Hair Loss Treatment with stem cells

A new medical technique for hair regeneration using stem cells solves in men and women with thin hair and thinning. Treatment is based on the isolation of a large number of proteins, which are released from the stem cells of fat. Innovative therapy has been developed and applied atin Greece in collaboration with the Centre for Plastic Surgery "Cosmetic Restoration" and pioneer biotechnology company regenerative «Theracell». The isolation of stem cells from fat is a revolutionary art, with impressive results and new perspectives in aesthetic medicine. Recent clinical studies show that the regenerative properties of stem cell derivatives have applications in aesthetic medicine and more specifically to regenerate skin and hair regeneration. The skilled and innovative way of making it rich in growth factors 'extract' activates the regeneration and growth of hair, without trichothylakeion and stem cell transplantation.
It is scientifically proven that up to 80% of the action of the stem due to the secretion of a large number of biomolecules, such as growth factors, primarily, cytokines and various enzymes. Very specifically, the fat stem cells secrete more than 700 such proteins, which play an important role in tissue remodeling and regeneration. These proteins act at the site of application:
• Enabling other skin cells (fibroblasts)
• Motivating other cells to migrate to the site of injury
• At the same time protect skin cells from oxidative stress
The treatment process comprises four steps:
1 Collection of a very small amount of fat,
2 Transfer the fat in the laboratory under specific conditions
3 Activation of stem cells,
4 Topical application of treatment in four monthly sessions
Derivatives of activated stem cells after their application to the scalp, promote the growth of hair follicles. Also activate the stem cells already present in the region, so that they start producing new hair and improve existing ones. This technique provides a good, and possibly unique, reliable, scientific alternative for patients who either do not want or are not suitable for hair transplantation. Particularly good results are shown in fine and short hair, which indicates to lengthen and thickens. The application of the new technique is easy, with local anesthesia by skilled, well-educated on the subject physician.

Source: www.ygeia360.gr

[35YrsAfter]

Also, an important note is that the Yale scientists discovered that the adipose precursor cells excrete 100 times as much of some growth factors as regular fat cells excrete. By injecting pure precursor cells (adipose derived stem cells) you are injecting 100 times more growth factors as you would if you just injected regular fat cells. So the key to this is to add the precursor fat cells, aka adipose derived stem cells so that you can bomb the follicles with the growth factors.

I'm sure a lot of you have already read this:

Valerie Horsley, Associate Professor of Molecular, Cellular, and Developmental Biology, hypothesized that adipocyte precursor cells were directly responsible for hair follicle growth by inducing the activation of follicular stem cells.

The team used various experimental methods, including histology and functional analysis, to visualize the interactions between the adipocyte lineage cells and the follicular stem cells. Several mouse models with genetic mutations at different stages of the adipogenesis pathway were used to see more specifically how adipocyte lineage cells contribute to the regulation of follicular stem cells. One mouse model with a defect in adipocyte precursor proliferation resulted in a significant decrease in hair growth levels. Transplanting wild-type adipocyte precursor cells into regions where such precursors were lacking in the mutant mice, however, prompted hair growth. Additional tests showed that adipocyte precursors drive platelet derived growth factor (PDGF) signaling, a process that induces the hair follicle’s initiation of the growth phase. The data collected from these experiments showed that adipocyte precursor cells are both necessary and sufficient to drive hair follicle growth.

35YrsAfter also posts as CITNews and works at Dr. Cole's office - forhair.com - Cole Hair Transplant, 1045 Powers Place, Alpharetta, Georgia 30009 - Phone 678-566-1011 - email 35YrsAfter at chuck@forhair.com
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