adipose-derived stem cell protein extract

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  • JZA70
    Member
    • May 2014
    • 71

    Originally posted by hellouser
    Yeah at least they're not making wild promises like Nigam did.
    What's sad is that he's still going strong at it.

    Comment

    • 158nikka
      Junior Member
      • Jul 2014
      • 4

      Hellouser, are you still using minoxidil and what is your current regimen?

      Comment

      • downandout
        Junior Member
        • Mar 2014
        • 25

        maybe a bigger company bought out the patent for this method that was used in the studies. Therefore, the reason it was so low key and unheard of. Another treatment swept under the rug..

        Comment

        • Xabi
          Junior Member
          • Jan 2013
          • 8

          Hey guys,

          This is Xabi from the north of Spain, just I want to share with you the feedback that I've had with ARS clinical. Feel free to comment, suggest, whatever, all the best n keep in touch :-)

          "Dear Mr. ,

          Thank you for your photos.

          For your case we propose to perform a FUE with 2.500 hair follicles or Stem Cell treatment with excellent results.

          The cost for each treatment, separetaly, will be 8.000 EUROS.

          Thank you and looking forward to your feedback.

          Sincerely yours,
          --
          Apostolos Karoutis, MSc, MBA
          Global Commercial Director
          ARSMEDICAL GmbH
          Health & Beauty Treatments
          Alpenstrasse 1, ZUG 6300 Switzerland
          +41 76 769 65 26 (Switzerland)
          +30 69 42 555 330 (Greece)
          akaroutis@arsmedical.info / www.arsmedical.info

          My response:

          "Good morning Apostolos,

          Thanks a lot for your time, my idea is to prove this new Stem Cell treatment (Adipose derived stem cell protein extract, right? or is there another one?), due to my business I don't have so much time. Next year will be the best time for me, I want to wait a little bit and read forum members' experiences about this treatment.

          I've been in London 3 years ago for example asking in person to Dr Raghu Reddy about PRP Acell and that treatment isn't appropriate.

          As I told you, I'm veteran and I've a big knowledge about this "hair" subject.

          One of my main doubts are:

          - Results, I know that no much clear proof already: http://news.yale.edu/2011/09/01/yale...-its-time-grow, http://www.balancehairrestoration.co...stem-cells.pdf, but, what can you show me to trust you?.

          - How many times do I have to go?, which is the time line of the treatment?, there're 12 hours driving from my house to your clinic in Switzerland and I could go more than 1-2 times.

          - Side effects?, SHOCK LOSS?, as I told you, I've been in Vancouver during my post surgery for one month in January 2010 and I know how hard is that one.

          Keep in touch, thanks a lot and I look forward to your answer.
          X "

          Comment

          • nameless
            Senior Member
            • Feb 2013
            • 965

            Originally posted by Xabi
            Hey guys,

            This is Xabi from the north of Spain, just I want to share with you the feedback that I've had with ARS clinical. Feel free to comment, suggest, whatever, all the best n keep in touch :-)

            "Dear Mr. ,

            Thank you for your photos.

            For your case we propose to perform a FUE with 2.500 hair follicles or Stem Cell treatment with excellent results.

            The cost for each treatment, separetaly, will be 8.000 EUROS.

            Thank you and looking forward to your feedback.

            Sincerely yours,
            --
            Apostolos Karoutis, MSc, MBA
            Global Commercial Director
            ARSMEDICAL GmbH
            Health & Beauty Treatments
            Alpenstrasse 1, ZUG 6300 Switzerland
            +41 76 769 65 26 (Switzerland)
            +30 69 42 555 330 (Greece)
            akaroutis@arsmedical.info / www.arsmedical.info

            My response:

            "Good morning Apostolos,

            Thanks a lot for your time, my idea is to prove this new Stem Cell treatment (Adipose derived stem cell protein extract, right? or is there another one?), due to my business I don't have so much time. Next year will be the best time for me, I want to wait a little bit and read forum members' experiences about this treatment.

            I've been in London 3 years ago for example asking in person to Dr Raghu Reddy about PRP Acell and that treatment isn't appropriate.

            As I told you, I'm veteran and I've a big knowledge about this "hair" subject.

            One of my main doubts are:

            - Results, I know that no much clear proof already: http://news.yale.edu/2011/09/01/yale...-its-time-grow, http://www.balancehairrestoration.co...stem-cells.pdf, but, what can you show me to trust you?.

            - How many times do I have to go?, which is the time line of the treatment?, there're 12 hours driving from my house to your clinic in Switzerland and I could go more than 1-2 times.

            - Side effects?, SHOCK LOSS?, as I told you, I've been in Vancouver during my post surgery for one month in January 2010 and I know how hard is that one.

            Keep in touch, thanks a lot and I look forward to your answer.
            X "

            You should use AAPE. That is the treatment that can really regrow your hair. AAPE is an extract from some very specific fat cells. That's the solution.

            Comment

            • Haircure
              Senior Member
              • May 2014
              • 126

              Originally posted by nameless
              You should use AAPE. That is the treatment that can really regrow your hair. AAPE is an extract from some very specific fat cells. That's the solution.
              There's a saying that a little knowledge is a dangerous thing, and this is exactly what applies to Nameless and his suggestions. AAPE is simply another POSSIBLE treatment, it is by no means a solution like the simple-minded fellow above chooses to believe.

              Comment

              • hellouser
                Senior Member
                • May 2012
                • 4419

                Originally posted by nameless
                You should use AAPE. That is the treatment that can really regrow your hair. AAPE is an extract from some very specific fat cells. That's the solution.
                How can you possibly say something like this without ever seeing VERIFIED results of AAPE on the scalp for hair loss? You are essentially lying to the hair loss community.

                Comment

                • hgs1989
                  Senior Member
                  • Mar 2014
                  • 164

                  Originally posted by hellouser
                  How can you possibly say something like this without ever seeing VERIFIED results of AAPE on the scalp for hair loss? You are essentially lying to the hair loss community.
                  Originally posted by Haircure
                  There's a saying that a little knowledge is a dangerous thing, and this is exactly what applies to Nameless and his suggestions. AAPE is simply another POSSIBLE treatment, it is by no means a solution like the simple-minded fellow above chooses to believe.
                  although I don't agree a lot with nameless posts, the science behind AAPE is solid. however my main concern is the product itself might be a scam i.e fancy water with no active ingredients and expensive one too. if not, then it should work. there is a lot of scientific evidence that supports it.I posted a lot of papers that supports it. the only thing that can stop it, is DHT. we can deal with this either orally or topically.the next generation in cosmetics is the use of growth factors to program our cells. not only cosmetics ,one day we might even skip the gym and still be in shape.its use will be widespread and all our concerns with cancer nonsense will be over.in fact the inhibition of some growth factors and activation of others might be used to treat cancer. I my self will try it but I need a skin injector to use. one that is called tappy tok tok or even jm turtle pin but I can't find a place to buy any of them.

                  Comment

                  • Haircure
                    Senior Member
                    • May 2014
                    • 126

                    Originally posted by hgs1989
                    although I don't agree a lot with nameless posts, the science behind AAPE is solid. however my main concern is the product itself might be a scam i.e fancy water with no active ingredients and expensive one too. if not, then it should work. there is a lot of scientific evidence that supports it.I posted a lot of papers that supports it. the only thing that can stop it, is DHT. we can deal with this either orally or topically.the next generation in cosmetics is the use of growth factors to program our cells. not only cosmetics ,one day we might even skip the gym and still be in shape.its use will be widespread and all our concerns with cancer nonsense will be over.in fact the inhibition of some growth factors and activation of others might be used to treat cancer. I my self will try it but I need a skin injector to use. one that is called tappy tok tok or even jm turtle pin but I can't find a place to buy any of them.
                    I stand by my statement that this is a POSSIBLE treatment and NOT a solution. I say this because in the study published in the American Journal of Cosmetic surgery, the results were mainly based on a VAG scale, meaning that hair growth was based on satisfaction and subjective visual interpretation by the patients. Also there were only 12 men involved in the study and from what I can recall, they made no mention of the results of all the men, rather they only displayed the results of 2. An objective approach involving the results of all the men, as well as increase in hair count in the treatment area might have been more useful in determining its effectiveness. From this study it seems that the treatment indeed works, but we don't know it's effectiveness and there are a few biases that need to be addressed, especially due to the subjective nature of the results.

                    If there are other articles, I'd be interested in knowing to what extent this treatment is useful, because as of now it is in my opinion not something significantly better than either Fin and Minox, because even though it's possibly a once every two years kind of treatment, it is highly likely to be much more expensive to be worth the benefit.

                    Comment

                    • nameless
                      Senior Member
                      • Feb 2013
                      • 965

                      Originally posted by hellouser
                      How can you possibly say something like this without ever seeing VERIFIED results of AAPE on the scalp for hair loss? You are essentially lying to the hair loss community.
                      I'm not lying.

                      You're lying.

                      There is one study that shows that AAPE grows hair. Some people are saying there are two studies demonstrating that AAPE grows hair. This one study, and possibly two studies, are direct evidence that AAPE grows hair. The study information are in credible peer-reviewed journal)s). This means I not only have direct evidence that AAPE grows hair; it also means that the evidence I have is also credible.

                      You have not one shred of evidence that I'm wrong. That means you're the one lying.

                      There is also solid peripheral evidence supporting my truth and dispelling your lie. I will state some of that peripheral evidence now:

                      1. Yale University has established that fat cells send the signal to follicles to grow hair. These signals from the fat cells are purportedly growth factors and proteins and these growth factors and proteins are likely the same growth factors and proteins that are in AAPE. At minimum these AAPE contains at least some of these growth factors and proteins.

                      2. Histogen uses some of the same growth factors and proteins that are inside AAPE and Histogen grows some hair. Histogen studies did not yield results as good as AAPE but in the AAPE studies the treatment was injected more often than Histogen was injected in the Histogen studies. That alone could, and likely does, explain why Histogen did not get results comparable to AAPE.

                      3. Dr. Gardner, who is a research scientist working on the Jahoda team, stated right here at this website that the Jahoda team will be incorporating fat cells into their cellular mix, which means that Jahoda/Gardner accept that there's something about fat cells that promote hair growth. Most likely, Gardner/Jahoda accept the results published by Yale.

                      4. Dr. Gardner stated that they wanted to use fat cells rather than the actual growth factors because they posit that growth factors are unstable and expensive. They did not say that the growth factors in fat cells are irrelevant; they simply said that they would rather use the fat cells than the growth factors themselves. This does make sense because if you can get the fat cells into the right place then those cells would be continuously producing the desired signals for follicles to grow hair. But we do not know for sure yet that fat cells will be as effective as the growth factors extracted from fat cells are (AAPE). It is possible that the growth factors from fat cells might work but the fat cells themselves might not work. So the scientific community's effort to utilize fat cells rather than growth factors from those same fat cells might be a multi-year waste of time.

                      5. My last piece of peripheral evidence that AAPE is a highly promising therapy that would likely give us what we want is posts by a man who calls himself Hellouser. You. You have posted repeatedly expressing optimism about fat cells for hair growth. You the person who calls me a liar (regarding my optimism about AAPE) has expressed optimism that fat cells might work and of course AAPE is at least some of the stuff that's inside of fat cells that makes fat cells promising.

                      6. You are optimistic about fat cells even though there is no direct evidence that injecting fat cells will work and like I've said, it is possible that the cells themselves might not work even though the growth factors from the cells appear to work. The cells are a different size, shape, and substance. They might not be able to get into every location necessary to do what's required of them. But the AAPE extract is a liquid derived from the cells and that could make it easier for the AAPE extract to get into every necessary nook and cranny of the follicles.

                      Comment

                      • nameless
                        Senior Member
                        • Feb 2013
                        • 965

                        Originally posted by Haircure
                        I stand by my statement that this is a POSSIBLE treatment and NOT a solution. I say this because in the study published in the American Journal of Cosmetic surgery, the results were mainly based on a VAG scale, meaning that hair growth was based on satisfaction and subjective visual interpretation by the patients. Also there were only 12 men involved in the study and from what I can recall, they made no mention of the results of all the men, rather they only displayed the results of 2. An objective approach involving the results of all the men, as well as increase in hair count in the treatment area might have been more useful in determining its effectiveness. From this study it seems that the treatment indeed works, but we don't know it's effectiveness and there are a few biases that need to be addressed, especially due to the subjective nature of the results.

                        If there are other articles, I'd be interested in knowing to what extent this treatment is useful, because as of now it is in my opinion not something significantly better than either Fin and Minox, because even though it's possibly a once every two years kind of treatment, it is highly likely to be much more expensive to be worth the benefit.
                        Here is what they said about the ALL of the test patients:

                        Results: All patients experienced increased hair growth
                        from the treatments with ADSC-CM. Four treatment sessions
                        performed within 3 to 4 months provided especially good
                        results. Scores on the visual analog scale increased with
                        treatment frequency. Statistical signifi cance was determined
                        by Friedman’s 2-way analysis of variance (P < .01) and
                        Wilcoxon’s signed rank test (P < .01).

                        They ALL grew hair. All of them. Did some grow more hair than others? It would appear so, but it would also appear that the ones who got lesser results are the ones who got less treatments. That just goes to show that you should use it at least once a month but I would use it once every 2 weeks for the first 4 months and then after that I would use it once every 4 to 6 months for maintenance. I think it is the best potential solution we have for the near-term, and I also think that if it turns out that injecting fat cells will not work even though injecting the growth factors from fat cells appears to work then it will take science years to figure that out and then years from now they will say "Well, the fat cells won't work, it's back to the drawing board." Is it possible that the fat cells could work? Yes. But we don't know that yet. And there's something else to keep in mind: it is not just any fat cells. it's a very specific group of fat cells that are needed.

                        Comment

                        • nameless
                          Senior Member
                          • Feb 2013
                          • 965

                          Originally posted by hgs1989
                          although I don't agree a lot with nameless posts, the science behind AAPE is solid. however my main concern is the product itself might be a scam i.e fancy water with no active ingredients and expensive one too. if not, then it should work. there is a lot of scientific evidence that supports it.I posted a lot of papers that supports it. the only thing that can stop it, is DHT. we can deal with this either orally or topically.the next generation in cosmetics is the use of growth factors to program our cells. not only cosmetics ,one day we might even skip the gym and still be in shape.its use will be widespread and all our concerns with cancer nonsense will be over.in fact the inhibition of some growth factors and activation of others might be used to treat cancer. I my self will try it but I need a skin injector to use. one that is called tappy tok tok or even jm turtle pin but I can't find a place to buy any of them.
                          I, and a few others, have tried to contact the scientists who worked with the one AAPE study we have all seen. We have tried to contact them at their stated email address and at the company whe3re some of them work. They do not respond. They are not trying to sell anything. It's pretty obvious that they did that study because they wanted to see something. But they are not selling the treatment. I do not believe this is a scam at all. I think it's Histogen only better because AAPE is produced by the body. It's the hair growing extract produced inside the fat cells in our bodies. It's what nature uses to grow hair on our heads.

                          Comment

                          • hgs1989
                            Senior Member
                            • Mar 2014
                            • 164

                            Originally posted by Haircure
                            I stand by my statement that this is a POSSIBLE treatment and NOT a solution. I say this because in the study published in the American Journal of Cosmetic surgery, the results were mainly based on a VAG scale, meaning that hair growth was based on satisfaction and subjective visual interpretation by the patients. Also there were only 12 men involved in the study and from what I can recall, they made no mention of the results of all the men, rather they only displayed the results of 2. An objective approach involving the results of all the men, as well as increase in hair count in the treatment area might have been more useful in determining its effectiveness. From this study it seems that the treatment indeed works, but we don't know it's effectiveness and there are a few biases that need to be addressed, especially due to the subjective nature of the results.


                            If there are other articles, I'd be interested in knowing to what extent this treatment is useful, because as of now it is in my opinion not something significantly better than either Fin and Minox, because even though it's possibly a once every two years kind of treatment, it is highly likely to be much more expensive to be worth the benefit.
                            When I say that there is a lot of studies and articles that support it, I mean the use of growth factors. any product that is based on a ****tail of signaling proteins should help with hair regrowth. the concentration and the frequency of the treatment is what need to be determined. this treatment(AAPE) is but one of those treatment based on growth factors. the study results is so good for me. I would be satisfied with these results. and there is another study posted by someone here http://www.haargroeispecialist.nl/re...ilot-study.pdf . this study was based on women and topical application of growth factors after micro needling. keep in mind that those results can be improved with further sessions; say every two weeks or one month. the down side is that it is a life time commitment. nothing will stop DHT from telling your follicle to shrink. so we need something to keep telling them to grow hair. I want more clinics to adopt the injection of growth factors. it will happen once we are comfortable with them.

                            Comment

                            • zeos
                              Member
                              • Oct 2013
                              • 54

                              @hgs1989

                              what do you(and others) think about this treatment?

                              Comment

                              • Haircure
                                Senior Member
                                • May 2014
                                • 126

                                Originally posted by zeos
                                @hgs1989

                                what do you(and others) think about this treatment?

                                http://integratedskincare.net/files/63390656.pdf
                                Seems sketchy to me, even though they have all those fancy diagrams, a few photos and simple explanations how it supposedly works, there any real evidence. By this I mean, any formal study done to explain and provide proof of their treatment as well as information regarding the details of their patient trials and results.

                                With that all being said, the results look pretty week in the photos, and by no means do they seem to indicate a more effective treatment than what we have unfortunately.

                                Comment

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