WCHR 2014 Presentations (Community-funded)

[FearTheLoss]

It's people such as yourself who keep the ACell discussion alive with incredible statements. For instance your statement; "No one here cares about Acell". Since only a very small percentage of forum visitors ever post, how in the world could you possibly know that no one here cares about ACell? You don't, so why do you even read my posts? I get a steady flow of emails from forum visitors interested in regenerative therapy. If you're not interested, then quit bringing it up.

35YrsAfter also posts as CITNews and works at Dr. Cole's office
forhair.com
Cole Hair Transplant
1070 Powers Place
Alpharetta, Georgia 30009
Phone 678-566-1011
email 35YrsAfter at chuck@forhair.com
The contents of my posts are my opinions and not medical advice
Please feel free to call or email me with any questions. Ask for Chuck

I personally am very interested in the possibilities of ACell. After reading a lot of literature on it, and previous posts, I can't wait to see how Dr. Wesley's next clinical trial results come out. Furthermore, I can't wait to see what the next few years will hold in terms of using PRP/Acell as a stand-alone treatment for prevention of hair loss. The science is there, that's undeniable. I'm failing to understand why forum members are so quick to shoot it down, but yet, they are also so quick to support snake oil with no scientific backing. It's baffling.

[walrus]

they are also so quick to support snake oil with no scientific backing. It's baffling.

What evidence is there for Acell working in this context? All I see are anecdotes which don't cut it.

[Thinning87]

Because every freaking thread in this forum is a chance for him to bring up something about Dr. Cole and what he does. If we had a thread on astronomy, he would find a way to link Dr. Cole to the conversation. This is not the Acell thread. There is an Acell thread so talk about Dr. Cole and Acell in there. If no one is posting in that thread, then that's probably a sign that no one cares.

I think the guy is trying to take advantage from the high increase in forum membership caused by Desmond's trip to publicize Dr. Cole. Like, who the hell needs to paste a 15 line signature at the end if every post??

[Hicks]

The ignore list is a very powerful tool on this forum. Some of you need to try it. It's great

[35YrsAfter]

Because every freaking thread in this forum is a chance for him to bring up something about Dr. Cole and what he does. If we had a thread on astronomy, he would find a way to link Dr. Cole to the conversation. This is not the Acell thread. There is an Acell thread so talk about Dr. Cole and Acell in there. If no one is posting in that thread, then that's probably a sign that no one cares.

I think the guy is trying to take advantage from the high increase in forum membership caused by Desmond's trip to publicize Dr. Cole. Like, who the hell needs to paste a 15 line signature at the end if every post??

I posted in this thread 25 times and mentioned Dr. Cole's name 2 times prior to this post.

My signature was nine lines. You make a good point though, it would look better if I didn't break it up into so many lines. Now can we please get back to discussing the research?

35YrsAfter also posts as CITNews and works at Dr. Cole's office
forhair.com - Cole Hair Transplant
1070 Powers Place Alpharetta, Georgia 30009 - Phone 678-566-1011
email 35YrsAfter at chuck@forhair.com
The contents of my posts are my opinions and not medical advice
Please feel free to call or email me with any questions. Ask for Chuck

[FearTheLoss]

Just took a look at this for the first time, VERY interesting stuff! Do you know if Dr. Cooley is continuing his studies? Is Dr. Cole continuing his ACell studies?

FTL

[hellouser]

Looks like wounding + Acell. Why not try to create a 4mm punch and pack it with acell into existing bald scalp?

In any case, those results look remarkable but then.... where the hell are REAL LIFE scenarios of this? Why hasn't a single person showed us their results?

[FearTheLoss]

Chuck,

Can you let us know if Dr. Cole and Dr. Cooley are, in fact, still working on ACell and regeneration? And what progress has been made?

[35YrsAfter]

Chuck,

Can you let us know if Dr. Cole and Dr. Cooley are, in fact, still working on ACell and regeneration? And what progress has been made?

Extracellular matrix plays two currently acknowledged roles in tissue remodeling/regeneration. It exists between the cells of all soft tissue in the body and serves as a "scaffolding" similar to how the stud framing on a house supports the sheetrock and siding. The newer discovery relates to extracellular matrix serving as a cell communication medium. Our most recent study demonstrated to us that ACell powder, mixed with hyaluronic acid (forming a gel) is far more effective than ACell powder alone, stuffed in an extraction site. ACell is a piece of the puzzle which may or may not endure as new research reveals more of the unknowns. We are currently using AmnioFix in hopes that this true biologic has more effective regenerative properties. In our most recent ACell study, we trimmed the hair and tattooed a 1cm square on the right and left side of our patient's head. We extracted an equal number of grafts from both sides. One side we treated with ACell powder alone and we didn't treat the opposite side with ACell powder. Without mixing the ACell powder with hyaluronic acid, the follicle regeneration in this case was disappointing. On the side we didn't use ACell at all, there were visible extraction sites. The side where the ACell powder was used, had far less hypopigmentation, but as I mentioned, without the hyaluronic acid, regeneration was disappointing with 2 out of 17 extraction sites growing hair. On the side where ACell was not used at all, zero extraction sites regrew hair.

On the same patient in a previous study, we extracted 12 grafts and treated the extraction sites with ACell + hyaluronic acid, forming a gel. 6 of the 12 extraction sites grew hairs.

Our most recent study included both ACell and AmnioFix made from donated human amniotic tissue. This is the tissue that is commonly discarded after childbirth and can now be donated because of its value in regenerative applications.

35YrsAfter also posts as CITNews and works at Dr. Cole's office - forhair.com - Cole Hair Transplant
1070 Powers Place Alpharetta, Georgia 30009 - Phone 678-566-1011 - email 35YrsAfter at chuck@forhair.com
The contents of my posts are my opinions and not medical advice
Please feel free to call or email me with any questions. Ask for Chuck

[35YrsAfter]

Looks like wounding + Acell. Why not try to create a 4mm punch and pack it with acell into existing bald scalp?

In any case, those results look remarkable but then.... where the hell are REAL LIFE scenarios of this? Why hasn't a single person showed us their results?

ACell which is an extracellular matrix product made from pig's bladder serves as only a piece of the tissue regeneration puzzle. We use ACell primarily in our FUE extraction sites but we also use it to improve the yield when beard hair is transplanted to balding areas on the scalp. Most men don't get excited about their donor density. They are of course happy to preserve as much of it as possible. When beard hair is blended properly with scalp hair it's often very difficult to locate the hairs. So a guy that got a 90% yield as opposed to 60% would have a difficult time showing that extra 30% off because there's nothing to compare that 90% with.

Hopefully/possibly with a boost from current regenerative research, ACell or perhaps AmnioFix will play an important role in improved follicle regeneration that will create the wow factor everyone is hoping for.

35YrsAfter also posts as CITNews and works at Dr. Cole's office - forhair.com - Cole Hair Transplant
1070 Powers Place Alpharetta, Georgia 30009 - Phone 678-566-1011 - email 35YrsAfter at chuck@forhair.com
The contents of my posts are my opinions and not medical advice
Please feel free to call or email me with any questions. Ask for Chuck

[FearTheLoss]

Extracellular matrix plays two currently acknowledged roles in tissue remodeling/regeneration. It exists between the cells of all soft tissue in the body and serves as a "scaffolding" similar to how the stud framing on a house supports the sheetrock and siding. The newer discovery relates to extracellular matrix serving as a cell communication medium. Our most recent study demonstrated to us that ACell powder, mixed with hyaluronic acid (forming a gel) is far more effective than ACell powder alone, stuffed in an extraction site. ACell is a piece of the puzzle which may or may not endure as new research reveals more of the unknowns. We are currently using AmnioFix in hopes that this true biologic has more effective regenerative properties. In our most recent ACell study, we trimmed the hair and tattooed a 1cm square on the right and left side of our patient's head. We extracted an equal number of grafts from both sides. One side we treated with ACell powder alone and we didn't treat the opposite side with ACell powder. Without mixing the ACell powder with hyaluronic acid, the follicle regeneration in this case was disappointing. On the side we didn't use ACell at all, there were visible extraction sites. The side where the ACell powder was used, had far less hypopigmentation, but as I mentioned, without the hyaluronic acid, regeneration was disappointing with 2 out of 17 extraction sites growing hair. On the side where ACell was not used at all, zero extraction sites regrew hair.

On the same patient in a previous study, we extracted 12 grafts and treated the extraction sites with ACell + hyaluronic acid, forming a gel. 6 of the 12 extraction sites grew hairs.

Our most recent study included both ACell and AmnioFix made from donated human amniotic tissue. This is the tissue that is commonly discarded after childbirth and can now be donated because of its value in regenerative applications.

35YrsAfter also posts as CITNews and works at Dr. Cole's office - forhair.com - Cole Hair Transplant
1070 Powers Place Alpharetta, Georgia 30009 - Phone 678-566-1011 - email 35YrsAfter at chuck@forhair.com
The contents of my posts are my opinions and not medical advice
Please feel free to call or email me with any questions. Ask for Chuck

What is Dr. Cole's future plans? To continue testing the ACell combined with hyaluronic acid? and do you see this is a procedure where he may get consistent results and eventually market regeneration?

[joachim]

6 of 12 extraction sites grew a hair, really? that would be fantastic already.
but was it only single hairs, or also 2, 3 and 4 hairs, depending on the extracted graft?

and was it a normal extraction or was it some kind of gho technique where follicles are only partly extracted and some cells left behind in the extraction site?

and also, when was this 12 graft test done? was it this year?
is it planned to do a larger session with 500 grafts or so?

if cole really can achieve about 50% regeneration consistently (average) and even make FUE scars invisible because healing is better with ACell, then this would be a game changer and make pilofocus obsolete.

i'm sure the 12 graft test was documented with pictures. why not share them here? (but a new thread should be created for it then)

[DeuceWillis]

Wow I sure do enjoy dropping by and getting a laugh at all these girls arguing all the time... Some one talked trash to me on here bc I said it was pointless to even send Desmond's ass to that conference bc once again we'll be in the same boat more info and nothing to do with it. And what do you know? It's nearly been a month and a half since that conference and nothing to show for it except for a bunch of "we're working on it" videos. They're still in the lab and were still going bald lol.. **** it I'm tired of caring

[hellouser]

6 of 12 extraction sites grew a hair, really? that would be fantastic already.
but was it only single hairs, or also 2, 3 and 4 hairs, depending on the extracted graft?

and was it a normal extraction or was it some kind of gho technique where follicles are only partly extracted and some cells left behind in the extraction site?

and also, when was this 12 graft test done? was it this year?
is it planned to do a larger session with 500 grafts or so?

if cole really can achieve about 50% regeneration consistently (average) and even make FUE scars invisible because healing is better with ACell, then this would be a game changer and make pilofocus obsolete.

i'm sure the 12 graft test was documented with pictures. why not share them here? (but a new thread should be created for it then)

Pilofocus is still scarless initially anyway, so no scarring whatsoever, not even a chance. But more importantly, graft survival and speed are far superior to FUE.

[35YrsAfter]

Pilofocus is still scarless initially anyway, so no scarring whatsoever, not even a chance. But more importantly, graft survival and speed are far superior to FUE.

Kudos to Dr. Wesley for taking on the Pilofocus project. I wish him great success.

For Hellouser:
1.) To make claims about what the Pilofocus can do while it's still in the development stage is premature.

2.) No visible scarring, perhaps. Scarring under the skin will occur whenever an instrument is inserted into the skin and moved about during the course of harvesting follicles.

3.) Faster than FUE? There is no FUE speed standard to base such a statement on. FUE tools and techniques are very different. Some doctors use needles while others use blunt punches while others use sharp punches. FUE extraction speed varies considerably from doctor to doctor. For instance some doctors extract grafts manually while others use a powered, doctor-controlled device. Manual extraction is slower and less accurate in experienced, capable hands. Patient's hair characteristics vary considerably and have a huge impact on extraction speed.


35YrsAfter also posts as CITNews and works at Dr. Cole's office - forhair.com - Cole Hair Transplant
1070 Powers Place Alpharetta, Georgia 30009 - Phone 678-566-1011 - email 35YrsAfter at chuck@forhair.com
The contents of my posts are my opinions and not medical advice
Please feel free to call or email me with any questions. Ask for Chuck