Clinical trial starting using Jahoda's method !

[TravisB]

How do we even know that thay are going to start trials soon?

They are recruiting participants since 2006 so it takes them quite a long time. Why would they all of sudden be starting a trial?

Besides why didn't anyone competent contact dr. Sung Jan-Lin yet?

This is his e-mail

jsjl2000tw@yahoo.com.tw

EDIT:

Ok, I've wrote him this e-mail:

Hello doctor.

Recently there are rumors that you will be starting the study soon.

I'm talking about that study - http://clinicaltrials.gov/ct2/show/study/NCT00506636

Can you confirm this?

Also how long do you estimate the trial will take?

Regards.

I'm curious if I will even get the response

[Dazza]

When they find a preventative cure there will be NO NEED to find a regrowth cure

Business wise what would you rather bring to market

A pill to stop all baldness that can be sold relatively cheap

Or

A cell based procedure that can be sold at a high price

[TravisB]

I just found another study lead by dr. Sung-Jan Lin

http://clinicaltrials.gov/show/NCT00509314

It's about vitiligo or something

Weirdly enough it has the exact same target number of participants (400) as the hairloss study, is also recruting, and all the dates are similar to the hairloss study

IMO it's not a good sign that it's another study that didn't start since 2006

[ytterligare]

However, something must have triggered the media's response two weeks ago.

[southern]

Desmond,
I made some screen shots of the "Scalable production of controllable dermal papilla spheroids on PVA surfaces and the effects of spheroid size on hair follicle regeneration" study. I'll type them here as soon as I can.

[nasazl1]

Forgot to add, it will be Follica (at any time) or Taiwan hair cloning and if one works I honestly believe within 3 years it will somehow be available, if not I'll live with what I've got.

Now I'll leave this thread for the experts to interpret the success or failure of the Taiwan study but I'll silently wait for 3=4 months to see if cloning works. Have to admit at least it is finally a real possibility of a real solution, possibly finally.

Good luck.

[TravisB]

Forgot to add, it will be Follica (at any time) or Taiwan hair cloning and if one works I honestly believe within 3 years it will somehow be available, if not I'll live with what I've got.

Now I'll leave this thread for the experts to interpret the success or failure of the Taiwan study but I'll silently wait for 3=4 months to see if cloning works. Have to admit at least it is finally a real possibility of a real solution, possibly finally.

Good luck.

No way any of these stem cell/cloning techniques will be available in 3 years

10-15 years - maybe

But not 3 years

Things progress with snail's pace in this business, you know

The best thing that can come to us before 2020 is CB-03-01

[hellouser]

No way any of these stem cell/cloning techniques will be available in 3 years

10-15 years - maybe

But not 3 years

Things progress with snail's pace in this business, you know

The best thing that can come to us before 2020 is CB-03-01

3 years? LOL, ARI spent around a decade squeezing money out of Aderans only to show anything but a full cure and fold. They even showed off timelines that had them released a product this year... actually, right about NOW; Q1 2014. God damn pathetic.

We had Dr. Roland Lauster come out with a working solution 3+ years ago already... I don't see anyone bothered by that but I do see a lot of people running around saying there's going to be a solution within the NEXT three years... what the f*ck?! It's like some members are actually part of the society that loves to continually humiliate bald guys by giving us false hope.

3 years, seriously? Based on what merit?

[huawei]

Hey brother yeah I managed to get my hands on ine of the papers but not all of them. Uploading them would be fantastic

Btw southern just posted some more studies. Is anyone able to maybe just copy paste the studies on here? This way we can have a great database of everything to do with this technique

Hi, sorry for getting back to you so late.

If you can post a compiled list of exactly what you're after I'll track them down tomorrow for you.

Edit: Positive things will happen for hair loss suffers sooner than later, as time goes on the half life of knowledge decreases.

[hellouser]

No way any of these stem cell/cloning techniques will be available in 3 years

10-15 years - maybe

But not 3 years

Things progress with snail's pace in this business, you know

The best thing that can come to us before 2020 is CB-03-01

Just to touch up on this...

https://www.youtube.com/watch?v=l7BApbu_YJ0

'It will be many years'. Also pay attention to her remark about the FDA (effing gatekeepers).

So uh... what needs to be done in order to go from Point A to Point B in LESS than many years? I'm sure all of us would vomit the next we heard '3-5 years'... what do we do?

[locke999]

Just to touch up on this...

https://www.youtube.com/watch?v=l7BApbu_YJ0

'It will be many years'. Also pay attention to her remark about the FDA (effing gatekeepers).

So uh... what needs to be done in order to go from Point A to Point B in LESS than many years? I'm sure all of us would vomit the next we heard '3-5 years'... what do we do?

This is a much more productive post than the ones you usually spew.

ASKING, how we can solve a problem. Instead of complaining about a problem. That is a good first step, and if you want to take it a step further, do your own research and resist complaining when noone does it for you.

[southern]

Hi, sorry for getting back to you so late.

If you can post a compiled list of exactly what you're after I'll track them down tomorrow for you.

Edit: Positive things will happen for hair loss suffers sooner than later, as time goes on the half life of knowledge decreases.

Great!

[ytterligare]

3 months? 30 years? both seems equally unrealistic to me. we have never been so close and never had such a promising perspective. Of course things will look different if they fail totally, but till that day, we have no reason to talk about another 30-50 years to wait.

[southern]

The treatment to create more hair comes down to Follica or Taiwan National University Hospital (TNUH) hair cloning. Seriously doubt anyone else is close and I would tend to believe it is TNUH hair cloning or litterally not anything else within the next decade.

The good thing given the patience size of TNUH Hair Loss treatment that if information is not overtly provided to the public it will be found invertly through a few of the 400 participants telling what there results are and probably with photos too.

As we should begin to hear about the results starting in June, just a guess based they stated they are about to start and if they start March 1 it takes 3-4 weeks for them to grow millions of cloned cells then it takes 6 weeks for those cells to get hair to a point to break the skin level so to speak. Then hair grows at 1/2 inch a month. Thus in June or July we should begin to here reports about hair growing, if it works.

Then we need to know about thickness, density, texture, angle, color, quality and success rate on the different patient types. And, I believe since it does not involve new drugs that if it really does work expect to see it 3 years from now. Why so fast? It is just a person's own hair cells being injected, why they are calling it a medical procedure. And people like us are going to push hard to make them to allow this one medical procedure be allowed ASAP expediting the process.

Either way just get this perfected ASAP or let it be known it does not work as I will no longer follow this cr@p and do not care if they have a real cure 10 years from now I just will not care.

We can go to the moon, achieve Fusion, do heart transplants but apparently growing Normal hair again on top of a person's head is impossible at least in a time period I care about. You will be seeing more posts about me on the TNUH cloned hair thread over the coming months. For me this treatment works over the coming months which I know is a long shot or forget about this topic forever. Not trying to be negative just tired of Waiting.

Well at least we find out if this treatment works in 3-4 months then it is over either way. I am going to assume 34 1/2 more months and I think that is a real target date until it hits the market, I am an optimist. Or, I throw my new combs get tossed in the trash can and I forever forget this topic.

It all comes down to the next 3-4 months for me. Good lluck.

The treatment to create more hair comes down to Follica or Taiwan National University Hospital (TNUH) hair cloning. Seriously doubt anyone else is close and I would tend to believe it is TNUH hair cloning or litterally not anything else within the next decade.

Donīt forget Tsuji Lab. If the dp expansion problem is solved, their technique wouldn't be that far from testing and clinical application (quite similar to a hair transplant)
Besides, there might be other options we don't know about, as happened with this case.

[southern]

2013 -"Scalable production of controllable dermal papilla spheroids(...)

Current surgical treatment of hair loss mainly relies on transplanting the remaining HFs to hairless areas. With the advent of tissue engineering and regenerative biology, bioengineering for HF neogenesis is of promising potential for treating such disorders. Before this technology can be applied clinically, a number of properties of the regenerated hairs need to be controlled to restore the natural look of hair patterns, including the number, thickness, spacing, alignment, color, etc. Since hair shows a patterned variation in sizes among body regions and up to thousands of new hairs can be needs in a single patient, a desirable thickness (or the diameter of the regenerated hair) and a high regenerative efficiency are vital to favorable clinical outcome. Prior work has focused more on the preservation of trichogenic ability of cells or the regeneration of the HF with a proper architecture. Whether and how the size of the regenerated HF can be controlled is yet to be explored. To achieve a reproducible high regenerative efficiency by an engineering approach will also help to bring such technology closer to clinical application.
HF is an ectodermal organ composed of two main parts, including the epithelium of keratinocytes and the mesenchyme of dermal papilla (DP) cells. HF development is regulated through a sophisticated epithelial – mesenchymal interaction. In adult mammals spontaneous HF neogenesis after injury is rarely observed with only few exceptions, such as deer antler regeneration and a large wound of a younger mouse. In addition to such spontaneous neogenesis, it was also found that freshly isolated or low-passage cultured DP cells are able to induce HF neogenesis when they are associated with competent epithelial keratinocytes. We and other groups have shown that the HF inductivity of cultured DP cells is better maintained when they are cultured as multicellular aggregates, a structure similar to the natural intercellular organization in vivo. Compared with mouse or rat DP cells, human DP cells expanded without Wnt/ b-catenin signaling activation are unable to induce HF neogenesis when they are transplanted as dissociated cells. Even freshly isolated human DP cells are not efficient in regenerating new HFs when they were directly transplanted. How to enhance the HF induction efficiency of cultured human DP cells is among the priority issues to be solved in bioengineering for clinical HF regeneration.
To tackle the issue of numbers and to control the spacing of regenerated HFs, we have proposed a 3 step procedure for clinical HF regeneration: expansion of DP cells in vitro, mass production of injectable DP aggregates in a bioreactor, and transplantation of DP aggregates to skin with appropriate spacing and arrangement. We have developed methods for mass production of DP aggregates or HF organ gems through substratum-facilitated self-assembly. Though DP aggregates obtained are able to induce HF neogenesis, there is variation of the size of regenerated HFs. Due to the inhomogeneous sizes of the DP aggregates generated by our previous methods, it is unclear whether the variation of the size of regenerated HFs is caused by the size inhomogeneity of transplanted DP aggregates or is a stochastic nature during HF regeneration.
In adult human, the variation of the hair thickness is believed to be controlled by the volume of DP. A larger DP containing more DP cells supports the growth of a larger HF. Comparing the cell numbers of a DP and the diameter of the hair shafts of rat whiskers, we also found a positive correlation of the DP cell numbers with the diameter of hair shafts. Though not tested yet it is intriguing to speculate that inductive DP aggregates of a larger volume or higher cell numbers may be able to induce neogenesis of larger HFs. This issue has not been systemically been investigated, possibly due, at least in part, to the lack of a reliable method of scalable production of size-controllable injectable DP spheroids for reproducible experimental testing. Several methods have been developed to culture dense microtissues including rotation, two-step rotation and flotation and hanging drop. However this methods are not suitable for automated scalable production of highly inductive DP spheroids and the ability to tightly control the size and cell number in each spheroid has not yet been demonstrated. Here, we develop a method that can be automated for mass production of human and rat DP spheroids with wide-range controllable size and cell number. We also examined the effect of the size of DP spheroids on the inductive efficiency and thickness of regenerated hairs.