Histogen - Documents and Presentations

[HairBane]

See greatjobs! response. I'd much rather pay for maintenance than butcher the back of my head leaving scars, thinner areas and limited donor that can only be done 1-3 times (depending on amount per session) where each time a procedure can cost upwards of $10,000.

Besides, the $1,000 figure is nothing more than my own example of a price point, its not even a prediction.

Apparently CB is an sebaceous gland inhibitor - do you think that could negatively impact neogenesis from treatments like HSC?

[inbrugge]

I'm down for this. I'm considering a minox+Cb+dermarolling treatment. That should last me about 2 years (hopefully). By then, it looks like we will actually have reasonable treatments by then.

I'm curious as you HairBane about CB possibly affecting this treatment. but I assume even in that case if you stopped using CB you should be ok (in a matter of time if not immediately)?

[hellouser]

Apparently CB is an sebaceous gland inhibitor - do you think that could negatively impact neogenesis from treatments like HSC?

This is the first time I've read anywhere that CB inhibits the sebaceous gland. Do you have a source for this?

[HairBane]

I remember reading it on here somewhere.. let me find the quote. Well apparently it reduces the size of the sebaceous gland. I'm not 100% sure what he means by that, but I thought that's one of the reasons it works for acne, by inhibiting the sebaceous gland so a spot can't develop.

Just a small summary for people who ask why CB should be better than fin, ru or similar products.

- an impressive reduction of sebacious gland size, observed in about 85% of treated subjects.
- a decrease in dermal fibrosis, indicator of inflammatory process, after treatment mainly with CB-03-01
- a reduction of vessel diameter of peribulbar microvasculature
- a reduction of inflammatory cells after treatment with CB-03-01

You can`t simply argue with "even castrated men dont see much regrow", because CB acts on more layers.

This is old news, but still, a lot don`t know those facts.
http://files.investis.com/csm/presen.../RDday2010.pdf - page 81 - 86

[youngin]

I remember reading it on here somewhere.. let me find the quote. Well apparently it reduces the size of the sebaceous gland. I'm not 100% sure what he means by that, but I thought that's one of the reasons it works for acne, by inhibiting the sebaceous gland so a spot can't develop.

I remember reading this in one of their presentations too. Sebaceous gland decreased in size.

[Kalio]

See greatjobs! response. I'd much rather pay for maintenance than butcher the back of my head leaving scars, thinner areas and limited donor that can only be done 1-3 times (depending on amount per session) where each time a procedure can cost upwards of $10,000.

Besides, the $1,000 figure is nothing more than my own example of a price point, its not even a prediction.

Histogen mentioned in one of their presentations that the cost per treatment would be something like $5k.

http://www.histogen.com/downloads/hisotgenforinvestor.pdf

[hellouser]

Perhaps we could reach out to Dr. Gail Naughton? She actually responds to many of her emails.

[mnhair]

maybe it's just me but the before and after photos are pretty underwhelming--it's probably a good supplement and that's about it. hopefully it'll be priced like that and not a full on solution.

[HairBane]

Perhaps we could reach out to Dr. Gail Naughton? She actually responds to many of her emails.

To ask her what?

[Javert]

"It would make no sense to expect that your existing follicles would no longer be effected by DHT."

Obviously. That doesn't mean Histogen won't be able to counteract the effects of DHT.

I guess if you continually received injections you could negate the effects of DHT by continually stimulating growth, but you're not going to change DHT levels or androgen receptors so DHT will still be attacking your hair. If that is the case then it will all come down to price. I would gladly stop taking fin if you could achieve this with a couple treatments a year as long as it's not too expensive.

Next time lead with this.

[Artha]

Histogen use cells from the back of the head (they are immune to DHT effect) so it would make sense if the new follicle made from those cells are immune to the DHT effect as well!

[HairBane]

Histogen use cells from the back of the head (they are immune to DHT effect) so it would make sense if the new follicle made from those cells are immune to the DHT effect as well!

No, they don't

[hellouser]

Histogen use cells from the back of the head (they are immune to DHT effect) so it would make sense if the new follicle made from those cells are immune to the DHT effect as well!

No, thats the Aderans and Replicel procedure (more or less).

[greatjob!]

"It would make no sense to expect that your existing follicles would no longer be effected by DHT."

Obviously. That doesn't mean Histogen won't be able to counteract the effects of DHT.

I guess if you continually received injections you could negate the effects of DHT by continually stimulating growth, but you're not going to change DHT levels or androgen receptors so DHT will still be attacking your hair. If that is the case then it will all come down to price. I would gladly stop taking fin if you could achieve this with a couple treatments a year as long as it's not too expensive.

Next time lead with this.

Nothing I said was incorrect.

Histogen is not going to effect the hair follicles susceptibility to DHT. True as far as anyone knows.

You could possibly maybe in theory use maintenance treatments to continue to induce growth to negate the effects of DHT. Maybe, but there is no proof of this and no proof that the treatment is compoundable or will continue to stimulate growth at the same rate.



Next time you should lead with this: silence or maybe STFU

[hellouser]

To ask her what?

'Apparently CB is an sebaceous gland inhibitor - do you think that could negatively impact neogenesis from treatments like HSC?'