Histogen - Documents and Presentations

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  • Scientalk56
    Senior Member
    • Nov 2012
    • 280

    Histogen - Documents and Presentations

    An Open Access Publisher & Scientific Events Organizer and other Open Access Resources


    This document summarizes clinical trial results for a treatment using conditioned media containing human proteins and growth factors secreted by embryonic-like cells to stimulate hair growth. A Phase I/II trial in 56 men found the treatment was safe and increased total hair count by 10.45% and terminal hair count by 19.5% at 12 weeks. A U.S. physician-sponsored trial also found the treatment was well-tolerated and increased hair growth in subjects by 6 weeks. Overall, the treatment shows promise for treating hair loss and expanding treatment options for older patients.


  • Artha
    Member
    • Jun 2013
    • 73

    #2
    It's only a matter of time before Histogen it hit the shelves now...

    Comment

    • NeedHairASAP
      Senior Member
      • Jul 2011
      • 1408

      #3
      Looks good. Not jaw dropping, but I would rather injections every 6 months than minox or fin every single day.

      Comment

      • cp9
        Member
        • Jun 2013
        • 86

        #4
        When will this be available? Asia 2015? I don't mind travelling, just take my money already.

        Comment

        • CAlex
          Senior Member
          • Feb 2011
          • 112

          #5
          The numbers from follica are all over the place and changing in some many peoples threads. These links are basically saying the average recipient of histogen so far can expect an

          Increase of 10% hair count?(please correct me if I misunderstood)

          As long as histogen strengthens current hair from dht damage and increases injected areas life expectancy they should definitely still come to market as a preventable treatment.

          BUT 10% as a growth treatment wouldn't even be noticeable. The numbers need to get to @ least a 40% increase in total hair count in the treatment area for this to be a success.

          the only way the 10% increase works is if its definitely compoundable.

          Comment

          • James7
            Member
            • Oct 2013
            • 93

            #6
            Originally posted by CAlex
            The numbers from follica are all over the place and changing in some many peoples threads. These links are basically saying the average recipient of histogen so far can expect an

            Increase of 10% hair count?(please correct me if I misunderstood)

            As long as histogen strengthens current hair from dht damage and increases injected areas life expectancy they should definitely still come to market as a preventable treatment.

            BUT 10% as a growth treatment wouldn't even be noticeable. The numbers need to get to @ least a 40% increase in total hair count in the treatment area for this to be a success.

            the only way the 10% increase works is if its definitely compoundable.
            You just need to watch the video i posted

            It is measured with a computer, as Dr naughton explains.

            As I understand it the 10% increase is in vellus hairs (which can also then eventually becomes terminal hair at a later time point).
            Presumably it either revives vellus hair (the ones smaller than visible by computer), to the point where the computer can now see it. Or possibly it encourages de-novo vellus hair, it's one of the two.

            The 20% increase are current vellus hairs that have been converted to terminal hairs.

            So looking at it that way, it makes perfect sense to me.

            'Hair count increase ranges from the 20s to the 60s', Dr Naughton explains.

            So that is from +20% to +60% increase! (with an actual terminal hair count increase around 45%-55% in the pictures shown)

            Also remember this is just the Primary Efficacy stage, so more studies will be done I expect, hopefully to further increase efficacy. Probably by doing more injections.

            Comment

            • rdawg
              Senior Member
              • Jun 2012
              • 996

              #7
              Very very good news, as expected this is a product that works but doesn't cure us fully.

              This is the next generation of products(Histogen, BIM, Replicel) in which we can get 20-60% recovery of our hair.

              The key question IMO that we need to answer next is what happens when combined with FIN?

              EDIT: and we have to recognize that they will be raising the dose in the next trial!! Could get even better results.

              Comment

              • Scientalk56
                Senior Member
                • Nov 2012
                • 280

                #8
                Originally posted by James7
                You just need to watch the video i posted

                It is measured with a computer, as Dr naughton explains.

                As I understand it the 10% increase is in vellus hairs (which can also then eventually becomes terminal hair at a later time point).
                Presumably it either revives vellus hair (the ones smaller than visible by computer), to the point where the computer can now see it. Or possibly it encourages de-novo vellus hair, it's one of the two.

                The 20% increase are current vellus hairs that have been converted to terminal hairs.

                So looking at it that way, it makes perfect sense to me.

                'Hair count increase ranges from the 20s to the 60s', Dr Naughton exp
                So that is from +20% to +60% increase! (with an actual terminal hair count increase around 45%-55% in the pictures shown)

                Also remember this is just the Primary Efficacy stage, so more studies will be done I expect, hopefully to further increase efficacy. Probably by doing more injections.

                total bullshit. Its 10 percent in hair count. Read again.

                Comment

                • Kiwi
                  Senior Member
                  • Mar 2011
                  • 1087

                  #9
                  Originally posted by Scientalk56
                  total bullshit. Its 10 percent in hair count. Read again.
                  Don't be a schmuck.

                  Even the pictures look better than 10%. Couple that with the information at hand I'd say Histogen 1. You 0.

                  Comment

                  • James7
                    Member
                    • Oct 2013
                    • 93

                    #10
                    Originally posted by Scientalk56
                    total bullshit. Its 10 percent in hair count. Read again.
                    Already read those links last year.

                    You need to watch the video of Dr Naughton speaking two weeks ago, here:



                    At 9mins 40 secs
                    '...a photograph and then measured with a computer, so we saw that patients had hair count increase as high as 61%, terminal hair great increase as well ...and so rangings from the 20s up to the 60s as well, so very,very strong efficacy'

                    quoted from Dr Gail Naughton in her own words, two weeks ago.

                    Also this is just the measurements at 3 months, it increases more at the 1 year time point

                    Comment

                    • Scientalk56
                      Senior Member
                      • Nov 2012
                      • 280

                      #11
                      Originally posted by Kiwi
                      Don't be a schmuck.

                      Even the pictures look better than 10%. Couple that with the information at hand I'd say Histogen 1. You 0.
                      You think i want histogen to fail?!

                      here's what Histogen presented:


                      and what pcitures are you talking about? male pictures or female pictures?

                      Comment

                      • rdawg
                        Senior Member
                        • Jun 2012
                        • 996

                        #12
                        When is this going into IIb!?

                        and even 10% at the worst is a great improvement over anything(it says 20% for terminal)

                        the video does say anywhere from 20-60% increase total though, Not sure if that was for the separate study she mentioned.

                        We also have to remember this is the I/IIa trial and they will definitely be testing higher doses or more frequent injections next time. Hopefully they also check the effects of Fin+Histogen.

                        Very very promising stuff IMO, You could say it could be better for sure, but it definitely works, I don't know how anyone can deny this.

                        Comment

                        • hellouser
                          Senior Member
                          • May 2012
                          • 4419

                          #13
                          Originally posted by rdawg
                          When is this going into IIb!?

                          and even 10% at the worst is a great improvement over anything(it says 20% for terminal)

                          the video does say anywhere from 20-60% increase total though, Not sure if that was for the separate study she mentioned.

                          We also have to remember this is the I/IIa trial and they will definitely be testing higher doses or more frequent injections next time. Hopefully they also check the effects of Fin+Histogen.

                          Very very promising stuff IMO, You could say it could be better for sure, but it definitely works, I don't know how anyone can deny this.
                          The stuff already performs WAY better than Finasteride. That alone should be a WELCOME addition to our available treatments...

                          Comment

                          • cp9
                            Member
                            • Jun 2013
                            • 86

                            #14
                            Oh man this is a game changer, I'm dropping fin for good.

                            Comment

                            • greatjob!
                              Senior Member
                              • Aug 2011
                              • 909

                              #15
                              Originally posted by Scientalk56
                              You think i want histogen to fail?!

                              here's what Histogen presented:


                              and what pcitures are you talking about? male pictures or female pictures?
                              Do you really expect to see crazy regrowth at 12 weeks? That's only at the 3 month mark...

                              Comment

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