How close are we? Really?

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  • Occulus
    Senior Member
    • Dec 2013
    • 109

    #16
    15 years, minimum. Nothing in the pipeline is promising enough to suggest it will produce marketable results, and even if one of them did, none of them are close to market under the best of circumstances. Don't kid yourself - Histogen, Replicel et. al are failures; if any of them had shown real promise, they would have been bought out by a major pharma a long, long time ago.

    If a cure happens within that timeframe, it will be from a protocol that has yet to be announced. The next treatment - not cure, not game-changer - to make it to market (IF it makes it to market) will be a bimatoprost topica that will have results slightly better than minoxidil.

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    • 534623
      Senior Member
      • Oct 2011
      • 1854

      #17
      Originally posted by Occulus
      15 years, minimum. Nothing in the pipeline is promising enough to suggest it will produce marketable results, and even if one of them did, none of them are close to market under the best of circumstances. Don't kid yourself - Histogen, Replicel et. al are failures; if any of them had shown real promise, they would have been bought out by a major pharma a long, long time ago.

      If a cure happens within that timeframe, it will be from a protocol that has yet to be announced. The next treatment - not cure, not game-changer - to make it to market (IF it makes it to market) will be a bimatoprost topica that will have results slightly better than minoxidil.
      +1

      Unfortunately, you're right. Especially when it comes to the bold parts of your post.

      Personally, I think real working/improved (but unfortunatly pricy) hair doubling procedures will dominate during the coming 10-15 years as "cure" for many guys out there. Such procedures shouldn't (normally aren't) much more dramatic than doing dermarolling procedures, but far more effective and, of course, PERMANENT.

      Comment

      • UK_
        Senior Member
        • Feb 2011
        • 2691

        #18
        Originally posted by Occulus
        15 years, minimum. Nothing in the pipeline is promising enough to suggest it will produce marketable results, and even if one of them did, none of them are close to market under the best of circumstances. Don't kid yourself - Histogen, Replicel et. al are failures; if any of them had shown real promise, they would have been bought out by a major pharma a long, long time ago.

        If a cure happens within that timeframe, it will be from a protocol that has yet to be announced. The next treatment - not cure, not game-changer - to make it to market (IF it makes it to market) will be a bimatoprost topica that will have results slightly better than minoxidil.
        If you're going to say "15 years" then I'm going to say "5000 years" - because both estimations are as accurate as each other being as though they've been literally pulled out of our asses.

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        • Scientalk56
          Senior Member
          • Nov 2012
          • 280

          #19
          Originally posted by Desmond84
          I think this is a safe estimate to make assuming all listed treatments come to fruition:

          2013-2016: Finasteride & Minoxidil

          2017-2020: CB-03-01, Histogen's HSC, Replicel, Follica

          2021-2025: Tsuji Lab (True Hair multiplication)

          2025 & Beyond: Luminescent hair
          Sadly I think its an "optimistic timeline".
          This is the best case scenario.
          The problem is, no one is proven to reverse baldness.. maybe grow some hair.. and untill then i will be norwood 7..

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          • Kiwi
            Senior Member
            • Mar 2011
            • 1087

            #20
            Originally posted by Scientalk56
            Sadly I think its an "optimistic timeline".
            This is the best case scenario.
            The problem is, no one is proven to reverse baldness.. maybe grow some hair.. and untill then i will be norwood 7..
            Of course something none of us know about might get released tomorrow. None of us know :P

            Comment

            • 25 going on 65
              Senior Member
              • Sep 2010
              • 1476

              #21
              To anyone who really cares about their hair. The smart approach is to plan the next 10 years of treatment as if NOTHING new will come out

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              • burtandernie
                Senior Member
                • Nov 2012
                • 1563

                #22
                True but there are other lesser knowns like this that could mimic CB 03 01 and maybe come out sooner or later so there are chances for things people never mention or didnt know about.


                Local Antiandrogen Therapy for the Treatment of Male Pattern Baldness

                A couple months ago i run into a study about a safe topical antiandrogen being developed by Novan Therapeutics:



                The hamster flank organ test results were very similar to RU58831: 55% of growth inhibition. Pretty exciting stuff, I think.

                They plan to finish phase II for acne in early 2014 testing the 3% concentration, which hopefully will work for MPB too, as it was the one exhibiting more powerful antiandrogenic activity during the study.

                Really sucks the company prioritize the acne version. Hate that… Are these pharma startups afraid of bringing something effective for hair loss sufferers? Always the same pattern…

                Anyway, plan to contact Novan soon and ask about the benefits of the acne formulation for hairloss.

                Comment

                • kobefan234
                  Senior Member
                  • Nov 2013
                  • 108

                  #23
                  I knew a dude was so fed up that he started injected Thymosin Beta 4 in his hairline...

                  Comment

                  • hellouser
                    Senior Member
                    • May 2012
                    • 4419

                    #24
                    Originally posted by kobefan234
                    I knew a dude was so fed up that he started injected Thymosin Beta 4 in his hairline...
                    And?

                    Comment

                    • Occulus
                      Senior Member
                      • Dec 2013
                      • 109

                      #25
                      Originally posted by UK_
                      If you're going to say "15 years" then I'm going to say "5000 years" - because both estimations are as accurate as each other being as though they've been literally pulled out of our asses.
                      No, it's not. 15 years is about the time a protocol goes from hypothesis to market. Since nothing in the current pipeline is going to work, then 15 years is the earliest something that COULD work would make it to market. Additionally, it would be surprising, given the current pace of biomedicine, if there wasn't a cure within 30 years. So, nothing's being puller out of anyone's asses - these are sensible timelines based on reality.

                      Comment

                      • kobefan234
                        Senior Member
                        • Nov 2013
                        • 108

                        #26
                        Originally posted by hellouser
                        And?
                        I have have not heard from him since. I am trying to convince an MD at my school to do it for me .. lol

                        I also talked with a guy from Australia who said TB4 worked "wonders" for him.

                        this was his protocol

                        "8mg week 1 (two shots @ 4mg Monday Thursday)
                        4mg week 2 (two shots @ 2mg Monday Thursday)
                        2mg week 3 (two shots @ 1mg Monday Thursday)
                        2mg week 4 (two shots @ 1mg Monday Thursday)
                        Then shots of .5mg twice a week for the following 4 weeks
                        Then maintenance dosages of .5mg-1mg every 2 weeks after that.

                        My hair is 100 times better than it was; thicker, healthier and new growth."

                        Comment

                        • Thinning87
                          Senior Member
                          • Dec 2012
                          • 839

                          #27
                          Well if it makes anyone feel better, replicel did get financing from a leading pharma to carry on. According to the logic used in earlier posts, this means they have a cure for sure

                          Comment

                          • Kiwi
                            Senior Member
                            • Mar 2011
                            • 1087

                            #28
                            Originally posted by Occulus
                            No, it's not. 15 years is about the time a protocol goes from hypothesis to market. Since nothing in the current pipeline is going to work, then 15 years is the earliest something that COULD work would make it to market. Additionally, it would be surprising, given the current pace of biomedicine, if there wasn't a cure within 30 years. So, nothing's being puller out of anyone's asses - these are sensible timelines based on reality.
                            Since none of them are going to work?

                            I've already seem photos if histogen results that work. Pilofocus will hopefully work.

                            So mr 4 post noob... Put a sock in it until you've done your research and take your whining elsewhere

                            Comment

                            • 534623
                              Senior Member
                              • Oct 2011
                              • 1854

                              #29
                              Originally posted by Thinning87
                              Well if it makes anyone feel better, replicel did get financing from a leading pharma to carry on. According to the logic used in earlier posts, this means they have a cure for sure
                              Yeah, but that happened BEFORE the ARI guys f...... up and faced the contrary.

                              I guess this "leading pharma" company regrets their action already...

                              Comment

                              • chimera
                                Senior Member
                                • Aug 2012
                                • 171

                                #30
                                Originally posted by Occulus
                                No, it's not. 15 years is about the time a protocol goes from hypothesis to market. Since nothing in the current pipeline is going to work, then 15 years is the earliest something that COULD work would make it to market. Additionally, it would be surprising, given the current pace of biomedicine, if there wasn't a cure within 30 years. So, nothing's being puller out of anyone's asses - these are sensible timelines based on reality.
                                I think In the next ten years (or less) we may have, not a cure, but a decent treatment...

                                As for a cure... I think is actually very close too, just not for any of us... I think the cure will be for the kids that right now are like 10 years or so...

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