Follica

[mnhair]

@hellouser, I really like you math approach.
I really do, your every post seems quite reasonable.

I just have one question for you, and I want to ask it to you from a novice point of view.
I haven't been around here as you did, so..respect to who knows more than me.

Let's take minoxidil and finasteride, the only two FDA approved substances.
Correct the following sentence if it is wrong:
"They were found to be effective against MPB by pure chance"

Let's say companies like Follica are working on a cure.

From my perspective there is an "edge" here.
The more effort is put to find a cure to MPB which is DIRECTED TOWARD IT, with associated costs, the bigger is the TOTAL RISK* to fail in the human trials (be it phase I, II, does not matter now).

*TOTAL RISK = losing every single dollar you invested in it.

What do you think about that?

Ps Yes, you could answer me, "one day or another, somebody will succeed".

Astressin-B would found out by chance (full hair regrowth on mice), and yet there's been no progress on that.

[moore]

What is the percentage of men that actually do something about their hair loss? I know its a rather small number, but the 10 billion dollar mark could be even higher IF there was a legitimate treatment as more men/women would be willing to actually spend the money for it, as a vast majority dont.

Lets do some math!

There are 7 billion people in the world, half of which are male. 50% of the worlds population was under 30 years of in 2012. So, we have 1.75 billion men in the world over the age of 30. Let's assume about 50% of the 1.75B men are balding, thus: 875 million. (25-33% of men are balding before 30 years of age, and up to around 66% by around age 50). But now we need to know how many men are actually seeking hair loss treatments. In China its around 47%. Let's go with that figure seeing how china's population trumps everything else. So now we have about 437 million men worldwide battling hair loss, roughly. Lets be generous and bring it down to around HALF of that; 220 million.

Now, this isn't even taking into account women or men under 30 years of age (which is a gigantic number in its own right).

Follica needs to hurry the hell up, those many hundreds of millions of people seeking treatments will have to be divided with Histogen and Replicel and if Pilofocus/Dr. Nigams hair doubling do in fact give regeneration, Follica is going to get an even smaller piece of the pie.

They're wasting precious time.

@hellouser, I really like you math approach.
I really do, your every post seems quite reasonable.

I just have one question for you, and I want to ask it to you from a novice point of view.
I haven't been around here as you did, so..respect to who knows more than me.

Let's take minoxidil and finasteride, the only two FDA approved substances.
Correct the following sentence if it is wrong:
"They were found to be effective against MPB by pure chance"

Let's say companies like Follica are working on a cure.

From my perspective there is an "edge" here.
The more effort is put to find a cure to MPB which is DIRECTED TOWARD IT, with associated costs, the bigger is the TOTAL RISK* to fail in the human trials (be it phase I, II, does not matter now).

*TOTAL RISK = losing every single dollar you invested in it.

What do you think about that?

Ps Yes, you could answer me, "one day or another, somebody will succeed".

[greatjob!]

There definitely will be a transitional period of time before proper treatments are widely accepted. But, I, and I'm sure you yourself will feel somewhat similar, would rather be first in line than have the rest of the world benefit from it. Obviously guys on the forums have been more progressive in finding treatments and we'll be the first to know. I hope all of us on the forums are amongst the first to get cured. I really don't want to any more time on these damn forums.

Oh yeah I was just speculating on the revenue figures you were posting, as I'm sure the general pubic will be behind the curve when a cure comes out. But I really could give a shit less because all of us in the forum communities will be first in line, and as selfish as it sounds I'll get my hair back and I could careless about anyone else or the company making money, F-it I just want hair!!

And I really would love to never spend one minute on this or any other hair loss forum!

[KJ1982]

That's histogen and replicel aiming for an Asia release, not Follica.

Ah, yes, of course. My mistake.

Still, here's hoping!

[hellouser]

That sounds about right and, so far as I'm concerned, would make the most sense; I can't remember where exactly I've seen or heard it, but I'm sure that a couple of sources close to those doing the research have said that they'd like to release in Asian territories in 2015 if possible.

If Phase IIb starts in 2014 then it's possible that such a projected date may be achievable.

That's histogen and replicel aiming for an Asia release, not Follica.

[SOTF]

I haven't looked into Follica in a while. Where are people getting this information from that they are in trials WITH Fgf9? When that xeconomy article came out people on this forum misinterpreted it as claiming they have regrown human hair with it IN trials already when the only trials they had undergone was wounding WITH LITHIUM.

[KJ1982]

My feelings tell me Follica have just finished phase IIA and are currently looking at going into Phase IIb/IIIa which have not started yet, so technically they are not conducting trials at the moment... I think Phase IIb/IIIa will start early - mid 2014.

That sounds about right and, so far as I'm concerned, would make the most sense; I can't remember where exactly I've seen or heard it, but I'm sure that a couple of sources close to those doing the research have said that they'd like to release in Asian territories in 2015 if possible.

If Phase IIb starts in 2014 then it's possible that such a projected date may be achievable.

[UK_]

My feelings tell me Follica have just finished phase IIA and are currently looking at going into Phase IIb/IIIa which have not started yet, so technically they are not conducting trials at the moment... I think Phase IIb/IIIa will start early - mid 2014.

[Artha]

Yeah and Puretech seem legit!

[TravisB]

Worse than your negativity is you spreading misinformation:



Notice that according to Follica's backing, they are about HALF WAY through human clinical trials.

Wow, this Puretech site is very good news indeed! I haven't seen it before.

So this basically confirms Follica are halfway through human trials (so they probably passed phase IIa).

But as far as I know they were injecting lithium since beginning of the trials, and they came up with injecting FGF-9 only recently.

So what we don't know is if they will continue the trials with FGF9 from Phase IIb, or will they have to start them from Phase I again?

Here, I found that FGF9 was only involved in preclinical trials so far. That's not the good news I think...

http://www.xconomy.com/boston/2013/06/03/hair-raising-follica-study-could-point-to-baldness-therapy/

[An earlier version of this story indicated that Follica used that protein, Fgf9, in its clinical trial. Olle later clarified that the protein, Fgf9, has only been involved in Follica's preclinical work so far].

[HairlossAt15]

Guys the clinical trials are ongoing and the science is sound (peer-reviewed and would not be published if was found to be inaccurate). Its pointless coming on here speculating 24/7 based off your made up opinions and putting down hard-working scientists far more important and better than you......... Not to mention 100s of 100s of 100s of times smarter.....

A simple google search can prove they are in clinical trials and a bit of time spent reading there peer-reviewed, painstakingly proved scientific papers(multiple tests on 100s of mice, tabulation and interpretation of data - which none of us would be able to make any sense of) is more than enough evidence they know what there doing. If you dont like it then perhaps you should get the correct qualifications and research it yourself.... But you would rather sit here moaning about how hard you're life is whilst they dedicate there lives to others.

Any confusion is generated by the media or your own inability to see the facts....

A harsh but real truth.

[Hair87]

Is well known that follica is not disclosing anything right now.

Excerpt from Xconomy

Few stories have struck a chord with Xconomy’s readership quite like that of Follica, the PureTech Ventures-incubated startup founded in 2006 with plans to combat male and female pattern baldness by using adult stem cells to grow new hair follicles. Unfortunately, details regarding Follica’s science—let alone its clinical progress—have been as tough to spot as a good toupee.

Link: http://www.xconomy.com/boston/2013/0...dness-therapy/

And there is a legit source which says Follica is indeed going through clinical trials

Excerpt from PR newswire

The company has run a series of human clinical trials, including a Phase IIa trial, which have demonstrated follicular neogenesis in humans for the first time.

Link: http://www.prnewswire.com/news-relea...209914441.html

[hellouser]

Oh ok I got ya. I did not realize what puretech was. Well that is good news. I do not remember either what Spencer and Joe said it was vague. I really hope this comes to fruition. I wish these companies would release updates every month instead of once or twice a year. I think I am going to try to stay off the site for at least a month, and just dermaroll. Its hard to stay off these sites though. Hellouser and everyone else I admire your drive and passion for curing this. I wish we could do more. If i hit the lottery tomorrow. I would hire a team of scientist and testters to find the right vehicle and safety of CB for everyone and make unlimited supplies of it and give it away, but hey its not going to happen. Good luck everyone. I will be back soon.

Good luck man! There's still plenty of room to experiment with! I'm still a firm believer that a combination of things may help and am on the lookout for injecting FGF-9 right after wounding. Just gotta see if its safe!

[deuce]

Oh ok I got ya. I did not realize what puretech was. Well that is good news. I do not remember either what Spencer and Joe said it was vague. I really hope this comes to fruition. I wish these companies would release updates every month instead of once or twice a year. I think I am going to try to stay off the site for at least a month, and just dermaroll. Its hard to stay off these sites though. Hellouser and everyone else I admire your drive and passion for curing this. I wish we could do more. If i hit the lottery tomorrow. I would hire a team of scientist and testters to find the right vehicle and safety of CB for everyone and make unlimited supplies of it and give it away, but hey its not going to happen. Good luck everyone. I will be back soon.

[hellouser]

Hellouser I hope you are right man. I am not arguing with you or trying to get in a pissing match. Hey if I was a prophet I sure would not be on this site. I am just a realist, and from lack of evidence there is nothing coming out soon. I hope it does, and what is a puretech venture. That site is not legit. You do not see anything on the clinicaltrials.gov about Follica. HEy I would agree with you, BUT THE PERSON ON FOLLICA"S RESEARCH TEAM TOLD ME THERE IS NOTHING IN TRIALS RIGHT NOW. Email them if you do not believe me. Best wishes people. I hope something does come out. I am just sick of false hopes.

Puretech Ventures is whats driving all of Follica's finances. Theyre the ones responsible for their funding. Without them, Follica wound need to have funding elsewhere. Looking at Puretech Ventures, looks like theyre involved in a lot of healthcare ventures, which is GOOD... unlike Aderans where they just sell f**king wigs! Anyway, the site is 100% legit. The information is there and absolutely verifies where Follica is.

Ignore what the PR person said to from Follica, I'd take their word with a grain of salt anyway. However, they could be just about to be starting Phase II trials, so maybe theyre not in trials RIGHT NOW, but we do know they finished Phase I. I can't remember, but did Spencer & Joe from Staten Island say they are IN phase II trials or WILL BE in Phase II trials?