(CB-03-01 Vehicle Research) PhD Student in Chemistry

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  • Hairismylife
    Senior Member
    • Jun 2012
    • 383

    lilpauly when will the Kane gel be available???

    Comment

    • lilpauly
      Senior Member
      • Feb 2012
      • 1084

      Originally posted by Hairismylife
      lilpauly when will the Kane gel be available???
      I don't know man Kane doesn't tell me much cause I tell forums. , when cb nano failed Kane got lots of emails regarding nano. I love nano products

      Comment

      • deuce
        Senior Member
        • May 2013
        • 209

        If cosmo puts out CB on the market for acne will it work for hair loss? Or will they have to find an effective vehicle or will the vehicle be effective for hair loss because it is effective for acne?

        Comment

        • chimera
          Senior Member
          • Aug 2012
          • 171

          Originally posted by deuce
          If cosmo puts out CB on the market for acne will it work for hair loss? Or will they have to find an effective vehicle or will the vehicle be effective for hair loss because it is effective for acne?
          I don't know man... lilpauli keeps saying the acne cream is no good, as it carries minaral oils which supposedly can't go through the hair shaft, but some time ago, a guy in this foum (I forgot who) told me that a guy in the SAGA tried CB on a replica of the acne cream and got awesome results...

          Comment

          • lilpauly
            Senior Member
            • Feb 2012
            • 1084

            Originally posted by chimera
            I don't know man... lilpauli keeps saying the acne cream is no good, as it carries minaral oils which supposedly can't go through the hair shaft, but some time ago, a guy in this foum (I forgot who) told me that a guy in the SAGA tried CB on a replica of the acne cream and got awesome results...
            Gk is the only person who got good results with the Cosmo cream. At least 50 reported no rests

            Comment

            • lothar99
              Member
              • Jul 2011
              • 36

              Originally posted by deuce
              If cosmo puts out CB on the market for acne will it work for hair loss? Or will they have to find an effective vehicle or will the vehicle be effective for hair loss because it is effective for acne?
              The "cosmo cream" everyone used a few years ago was made wrong

              Comment

              • lilpauly
                Senior Member
                • Feb 2012
                • 1084

                Lothar gk got results on the wrong version lol anyways cb right now is not worth it until a vehicle can be found

                Comment

                • chimera
                  Senior Member
                  • Aug 2012
                  • 171

                  Originally posted by lilpauly
                  Gk is the only person who got good results with the Cosmo cream. At least 50 reported no rests
                  Ouch, that sucks

                  Comment

                  • burtandernie
                    Senior Member
                    • Nov 2012
                    • 1563

                    Why cant we just use this if it works and cosmo proved it worked? Im not a chemistry/biology person. So it uses propulsion and moves in electric field transdermally?

                    About iontophoresis
                    Iontophoresis is a non-invasive method of propelling high concentrations of a
                    charged substance, normally a medication or bioactive agent, transdermally by a repulsive electromotive force using a small electrical charge applied to an iontophoretic chamber containing a similarly charged active agent and its vehicle. One or two chambers are filled with a solution containing an active ingredient and its solvent, also called the vehicle. The positively charged chamber, called the anode, will repel a positively charged chemical,
                    whereas the negatively charged chamber, called the cathode , will repel a negatively charged chemical into the skin. Iontophoresis is well classified for use in transdermal drug delivery. Unlike transdermal patches, this method relies on ac
                    tive transportation within an electric
                    field

                    Comment

                    • Knockin on NW4
                      Member
                      • Jul 2012
                      • 81

                      Oleyl seems to be an important penetration enhancer for CB. But everyone who has tried 9:1 PG to Oleyl says its way way too harsh, causing instant shedding, plus its super greasy.


                      Oleyl is Fatty, so it wont mix with ethanol. A couple of peeps are trying oleyl in emu oil for their CB vehicle. here is some number from a 2010 cosmo study


                      2010 cosmo study, page 74.

                      CA in PG 12.3ug/g skin concentration and penetration of undetectable
                      CA in PG/OL 89.4 ug/g concentration and penetration of 141ng/ml/hr
                      CB in PG 36 skin conc and penetration of 7
                      CB in PG/OL 231 skin conc and penetration of 1410

                      CB in 9:1 PG OLEYL on human skin in vitro

                      Comment

                      • Difthin
                        Junior Member
                        • Aug 2013
                        • 22

                        Originally posted by lilpauly
                        Lothar gk got results on the wrong version lol anyways cb right now is not worth it until a vehicle can be found
                        Might be dumb, Im pretty much a noob in hairlossworld, but couldnt you use some kind of dermaroller with epidural (hollow) needles to get the stuff directly to the area where it needs to be? Im sure some one smarter than me would be able to create such a device. Just a thought.

                        Comment

                        • lilpauly
                          Senior Member
                          • Feb 2012
                          • 1084

                          Originally posted by Difthin
                          Might be dumb, Im pretty much a noob in hairlossworld, but couldnt you use some kind of dermaroller with epidural (hollow) needles to get the stuff directly to the area where it needs to be? Im sure some one smarter than me would be able to create such a device. Just a thought.
                          I think the new israel device would be great .

                          Comment

                          • lilpauly
                            Senior Member
                            • Feb 2012
                            • 1084

                            2 people reported results from using emu on the Korean forum . I think drap was only usi g emu . This was September

                            Comment

                            • Difthin
                              Junior Member
                              • Aug 2013
                              • 22

                              Originally posted by lilpauly
                              I think the new israel device would be great .
                              Has injecting growth factors ever been tried or is the chance of the drug becoming systemic just too high?

                              And if I understand you correctly the Israeli are allready using some sort of hollow needle dermaroller in the piloxil method?

                              edit: accidentally a word

                              Comment

                              • simba
                                Senior Member
                                • Jul 2013
                                • 103

                                Originally posted by burtandernie
                                Why cant we just use this if it works and cosmo proved it worked? Im not a chemistry/biology person. So it uses propulsion and moves in electric field transdermally?
                                We couldnt figure out what to buy or how to use it, if you have any ideas that would be appreciated.

                                I also dont understand why no one has tried oleyl with PG but thats just me

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