lilpauly when will the Kane gel be available???
(CB-03-01 Vehicle Research) PhD Student in Chemistry
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I don't know man... lilpauli keeps saying the acne cream is no good, as it carries minaral oils which supposedly can't go through the hair shaft, but some time ago, a guy in this foum (I forgot who) told me that a guy in the SAGA tried CB on a replica of the acne cream and got awesome results...Comment
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I don't know man... lilpauli keeps saying the acne cream is no good, as it carries minaral oils which supposedly can't go through the hair shaft, but some time ago, a guy in this foum (I forgot who) told me that a guy in the SAGA tried CB on a replica of the acne cream and got awesome results...Comment
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Why cant we just use this if it works and cosmo proved it worked? Im not a chemistry/biology person. So it uses propulsion and moves in electric field transdermally?
About iontophoresis
Iontophoresis is a non-invasive method of propelling high concentrations of a
charged substance, normally a medication or bioactive agent, transdermally by a repulsive electromotive force using a small electrical charge applied to an iontophoretic chamber containing a similarly charged active agent and its vehicle. One or two chambers are filled with a solution containing an active ingredient and its solvent, also called the vehicle. The positively charged chamber, called the anode, will repel a positively charged chemical,
whereas the negatively charged chamber, called the cathode , will repel a negatively charged chemical into the skin. Iontophoresis is well classified for use in transdermal drug delivery. Unlike transdermal patches, this method relies on ac
tive transportation within an electric
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Oleyl seems to be an important penetration enhancer for CB. But everyone who has tried 9:1 PG to Oleyl says its way way too harsh, causing instant shedding, plus its super greasy.
Oleyl is Fatty, so it wont mix with ethanol. A couple of peeps are trying oleyl in emu oil for their CB vehicle. here is some number from a 2010 cosmo study
2010 cosmo study, page 74.
CA in PG 12.3ug/g skin concentration and penetration of undetectable
CA in PG/OL 89.4 ug/g concentration and penetration of 141ng/ml/hr
CB in PG 36 skin conc and penetration of 7
CB in PG/OL 231 skin conc and penetration of 1410
CB in 9:1 PG OLEYL on human skin in vitroComment
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Might be dumb, Im pretty much a noob in hairlossworld, but couldnt you use some kind of dermaroller with epidural (hollow) needles to get the stuff directly to the area where it needs to be? Im sure some one smarter than me would be able to create such a device. Just a thought.Comment
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Might be dumb, Im pretty much a noob in hairlossworld, but couldnt you use some kind of dermaroller with epidural (hollow) needles to get the stuff directly to the area where it needs to be? Im sure some one smarter than me would be able to create such a device. Just a thought.Comment
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Has injecting growth factors ever been tried or is the chance of the drug becoming systemic just too high?
And if I understand you correctly the Israeli are allready using some sort of hollow needle dermaroller in the piloxil method?
edit: accidentally a wordComment
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I also dont understand why no one has tried oleyl with PG but thats just meComment
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